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William Wijns, MD.doc.doc William Wijns, MD.doc.doc Document Transcript

  • William WIJNS, MD, FESC Born September 26, 1951, Molenbeek (Belgium) Present position and address Co-Director, Cardiovascular Centre, O.L.V.Z. Aalst Moorselbaan 164, B 9300 Aalst, Belgium Education July 1976: Medical Doctor, U.C.L. (Grande Distinction) 1976 - 1981: Fellowship in Internal Medicine and Cardiology, St Luc University Hospitals, University of Louvain Medical School July 1981: Certified Specialist in Internal Medicine 1981 - 1984: Thoraxcenter and Erasmus University, Rotterdam, The Netherlands Feb 1983: Specialisten Registratie Commissie, The Netherlands 1984 - 1985: Research Fellowship, Division of Nuclear Medicine and Biophysics, University of California at Los Angeles (U.S.A.). 1986 - 1987: Social Service, Cardio-Pulmonary Physiopathology Unit, University of Louvain Medical School ESC and other professional organisations 1992 - 1994: Secretary of the Working Group on Coronary Circulation of the European Society of Cardiology (ESC) 1994 - 1996: Vice-Chairman of the ESC Working Group on Coronary Circulation 1996 - 1998: Chairman of the ESC Working Group on Coronary Circulation 1996 - 2000: Member of the Executive Scientific Committee of the ESC Chairman of the FOCUS sub-committee (1999-2000) 2000 - 2003: Chairman of the ESC Euro Heart Survey on Myocardial Revascularization 2002 - 2004: Chairman ESC Congress Programme Committee and Member of the ESC Board 2004 - 2006: Vice-President, External Relations, ESC 2006 – 2009 President, European Association of Percutaneous Cardiovascular Interventions (EAPCI) 2006 - 2010: Board Member and Chair EU Relations Committee, European Society of Cardiology 2006 – 2010: Board Member, World Heart Federation Membership Scientific Societies: Belgian Society of Cardiology, American Heart Association (Fellow Circulation Council), Belgian Working Group on Interventional Cardiology, French Society of Cardiology (Membre Etranger), Euro PCR (member of Board Directors) Membership Legal Authorities: Belgian Peer Review Council for Cardiology (2000 - 2006) 1
  • Editorial Boards Editorial Board Member for European Heart Journal, EuroIntervention Journal, Dialogues in Cardiovascular Medicine, International Journal of Cardiac Imaging, International Journal of Cardiac Interventions, Italian Heart Journal. Reviewer for American Journal of Cardiology, American Journal of Physiology, Circulation, Circulation Research, EuroIntervention Journal, European Heart Journal, Heart, Heart Drug, International Journal of Cardiac Imaging, International Journal of Cardiac Interventions, Journal of the American College of Cardiology, Journal of Nuclear Cardiology, Journal of Nuclear Medicine, The Lancet. Publications More than 300 publications in peer reviewed journals. Reseach interest Research efforts focus on the development and validation of innovative techniques in interventional cardiology such as intracoronary physiological measurements, drug-eluting stents and more recently, cell therapy and applications of multi-detector CT angiography. Steering committees 1989 - ongoing: Steering Committee, Critical Event Committee member/chairman/principal investigator of various international multicenter clinical trials 1989 - 1995: Coordinator of the Cardiology Branch of the Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration", sponsored by the European Community 2004: Member of the ESC Study Group on Stem Cells and Regeneration of the Heart 2006: Co-Chair ESC Task Force on drug-eluting stent safety 2
  • William Wijns, MD. PhD. FESC, FAHA List of Publications Manuscripts Book chapters 3 View slide
  • Lack of adaptation of pancreatic colipase in rats and mice. Vandermeers-Piret MC, Vandermeers A, Wijns W, Rathé J, Christophe J. Am J Physiol. 1977 Feb;232(2):E131-5. Contrasting effect on cardiac output of digoxin and gitoxin in humans during congestive heart failure. Col J, Wijns W, Brasseur L, Lesne M. Int J Clin Pharmacol Ther Toxicol. 1981 Jul;19(7):314-8. The effect of intracoronary thrombolysis with streptokinase on myocardial thallium distribution and left ventricular function assessed by blood-pool scintigraphy. Simoons ML, Wijns W, Balakumaran K, Serruys PW, van den Brand M, Fioretti P, Reiber JH, Lie P, Hugenholtz PG. Eur Heart J. 1982 Oct;3(5):433-40. No abstract available. Clinical validation of fully automated computation of ejection fraction from gated equilibrium blood-pool scintigrams. Reiber JH, Lie SP, Simoons ML, Hoek C, Gerbrands JJ, Wijns W, Bakker WH, Kooij PP. J Nucl Med. 1983 Dec;24(12):1099-107. Is transluminal coronary angioplasty mandatory after successful thrombolysis? Quantitative coronary angiographic study Serruys PW, Wijns W, van den Brand M, Ribeiro V, Fioretti P, Simoons ML, Kooijman CJ, Reiber JH, Hugenholtz PG. Br Heart J. 1983 Sep;50(3):257-65. No abstract available. Pulmonary vascular tone is a determinant of basal lung perfusion in normal seated subjects. Nemery B, Wijns W, Piret L, Caùwe F, Brasseur L, Frans A. J Appl Physiol. 1983 Jan;54(1):262-6. Prediction of mortality in hospital survivors of myocardial infarction. Comparison of predischarge exercise testing and radionuclide ventriculography at rest. Fioretti P, Brower RW, Simoons ML, Das SK, Bos RJ, Wijns W, Reiber JH, Lubsen J, Hugenholtz PG. Br Heart J. 1984 Sep;52(3):292-8. Assessment of percutaneous transluminal coronary angioplasty by quantitative coronary angiography: diameter versus densitometric area measurements. Serruys PW, Reiber JH, Wijns W, van den Brand M, Kooijman CJ, ten Katen HJ, Hugenholtz PG. Am J Cardiol. 1984 Sep 1;54(6):482-8. Left ventricular performance, regional blood flow, wall motion, and lactate metabolism during transluminal angioplasty. 4 View slide
  • Serruys PW, Wijns W, van den Brand M, Meij S, Slager C, Schuurbiers JC, Hugenholtz PG, Brower RW. Circulation. 1984 Jul;70(1):25-36. The exercise response in idiopathic dilated cardiomyopathy. Kirlin PC, Das S, Zijnen P, Wijns W, Domenicucci S, Roelandt J, Pitt B. Clin Cardiol. 1984 Apr;7(4):205-10. Coronary artery dimensions from cineangiograms methodology and validation of a computer-assisted analysis procedure. Reiber JH, Kooijman CJ, Slager CJ, Gerbrands JJ, Schuurbiers JC, Den Boer A, Wijns W, Serruys PW, Hugenholtz PG. IEEE Trans Med Imaging. 1984;3(3):131-41. Validation of radionuclide cardiac output measurements during exercise. Melin JA, Wijns W, Robert A, Nannan M, De Coster P, Beckers C, Detry JM. J Nucl Med. 1985 Dec;26(12):1386-93. Erratum in: J Nucl Med 1987 Mar;28(3):401-2. Values and limitations of transstenotic pressure gradients measured during percutaneous coronary angioplasty. Serruys PW, Wijns W, Reiber JH, de Feyter P, van den Brand M, Piscione F, Hugenholtz PG. Herz. 1985 Dec;10(6):337-42. Coronary angioplasty in myocardial infarction. Wijns W, Serruys PW. Am J Cardiol. 1985 Dec 1;56(15):1004. No abstract available. Effects of short-term intravenous administration of diltiazem on left ventricular function and coronary hemodynamics in patients with coronary artery disease. Serruys PW, Suryapranata H, Planellas J, Wijns W, Vanhaleweyk G, Jaski BE, Hugenholtz PG. J Cardiovasc Pharmacol. 1985 Nov-Dec;7(6):1138-48. Acute effects of intravenous nisoldipine on left ventricular function and coronary hemodynamics. Serruys PW, Suryapranata H, Planellas J, Wijns W, Vanhaleweyk GL, Soward A, Jaski BE, Hugenholtz PG. Am J Cardiol. 1985 Jul 1;56(1):140-6. Alternative diagnostic strategies for coronary artery disease in women: demonstration of the usefulness and efficiency of probability analysis. Melin JA, Wijns W, Vanbutsele RJ, Robert A, De Coster P, Brasseur LA, Beckers C, Detry JM. Circulation. 1985 Mar;71(3):535-42. 5
  • Limitations of a QRS scoring system to assess left ventricular function and prognosis at hospital discharge after myocardial infarction. Fioretti P, Brower RW, Lazzeroni E, Simoons ML, Wijns W, Reiber JH, Bos RJ, Hugenholtz PG. Br Heart J. 1985 Mar;53(3):248-52. Ventricular volumes during upright exercise. Wijns W, Melin JA, Younis L, Detry JM. Eur Heart J. 1985 Feb;6(2):185. No abstract available. Assessment of short-, medium-, and long-term variations in arterial dimensions from computer-assisted quantitation of coronary cineangiograms. Reiber JH, Serruys PW, Kooijman CJ, Wijns W, Slager CJ, Gerbrands JJ, Schuurbiers JC, den Boer A, Hugenholtz PG. Circulation. 1985 Feb;71(2):280-8. Quantitative angiography of the left anterior descending coronary artery: correlations with pressure gradient and results of exercise thallium scintigraphy. Wijns W, Serruys PW, Reiber JH, van den Brand M, Simoons ML, Kooijman CJ, Balakumaran K, Hugenholtz PG. Circulation. 1985 Feb;71(2):273-9. Early detection of restenosis after successful percutaneous transluminal coronary angioplasty by exercise-redistribution thallium scintigraphy. Wijns W, Serruys PW, Reiber JH, de Feyter PJ, van den Brand M, Simoons ML, Hugenholtz PG. Am J Cardiol. 1985 Feb 1;55(4):357-61. Predictive value of early maximal exercise test and thallium scintigraphy after successful percutaneous transluminal coronary angioplasty. Wijns W, Serruys PW, Simoons ML, van den Brand M, de Feijter PJ, Reiber JH, Hugenholtz PG. Br Heart J. 1985 Feb;53(2):194-200. Radionuclide absolute left ventricular volumes during upright exercise: validation in normal subjects by simultaneous hemodynamic measurements. Wijns W, Melin JA, Decoster PM, Piret LJ, Beckers C, Detry JM. Eur J Nucl Med. 1985;10(3-4):111-7. Early angiography after myocardial infarction: what have we learned? de Feyter PJ, van den Brand M, Serruys PW, Wijns W. Am Heart J. 1985 Jan;109(1):194-9. No abstract available. Effect of intracoronary thrombolytic therapy on global and regional left ventricular function. A three year experience with randomization. 6
  • Serruys PW, Simoons ML, de Feyter PJ, Suryapranata H, Wijns W, van den Brand M, Planellas J, van Domburg R, Hugenholtz PG. Z Kardiol. 1985;74 Suppl 6:117-27. Elective PTCA of totally occluded coronary arteries not associated with acute myocardial infarction; short-term and long-term results. Serruys PW, Umans V, Heyndrickx GR, van den Brand M, de Feyter PJ, Wijns W, Jaski B, Hugenholtz PG. Eur Heart J. 1985 Jan;6(1):2-12. Left ventricular function during transluminal angioplasty: a haemodynamic and angiographic study. Serruys PW, Wijns W, van den Brand M, Mey S, Slager C, Schuurbiers JC, Hugenholtz PG, Brower RW. Acta Med Scand Suppl. 1985;694:197-206. Review. Long term improvement in global left ventricular function after early thrombolytic treatment in acute myocardial infarction. Report of a randomised multicentre trial of intracoronary streptokinase in acute myocardial infarction. Res JC, Simoons ML, van der Wall EE, van Eenige MJ, Vermeer F, Verheugt FW, Wijns W, Braat S, Remme WJ, Serruys PW, et al. Br Heart J. 1986 Nov;56(5):414-21. Early changes in wall motion and wall thickness during percutaneous transluminal coronary angioplasty in man. Serruys PW, Jaski B, Wijns W, Piscione F, ten Kate F, de Feyter P, van den Brand M, Hugenholtz PG. Can J Cardiol. 1986 Jul;Suppl A:221A-232A. Coronary angioplasty of the unstable angina related vessel in patients with multivessel disease. de Feyter PJ, Serruys PW, Arnold A, Simoons ML, Wijns W, Geuskens R, Soward A, van den Brand M, Hugenholtz PG. Eur Heart J. 1986 Jun;7(6):460-7. Effects of intracoronary thrombolysis on global left ventricular function assessed by an automated edge detection technique. van der Wall EE, Res JC, van Eenige MJ, Verheugt FW, Wijns W, Braat S, de Zwaan C, Remme WJ, Vermeer F, Reiber JH, et al. J Nucl Med. 1986 Apr;27(4):478-83. Preservation of global and regional left ventricular function after early thrombolysis in acute myocardial infarction. Serruys PW, Simoons ML, Suryapranata H, Vermeer F, Wijns W, van den Brand M, Bär F, Zwaan C, Krauss XH, Remme WJ, et al. J Am Coll Cardiol. 1986 Apr;7(4):729-42. 7
  • The haemodynamic and myocardial effects of dopexamine: a new beta 2-adrenoceptor and dopaminergic agonist. Jaski BE, Wijns W, Foulds R, Serruys PW. Br J Clin Pharmacol. 1986 Apr;21(4):393-400. Effect of coronary occlusion during percutaneous transluminal angioplasty in humans on left ventricular chamber stiffness and regional diastolic pressure-radius relations. Wijns W, Serruys PW, Slager CJ, Grimm J, Krayenbuehl HP, Hugenholtz PG, Hess OM. J Am Coll Cardiol. 1986 Mar;7(3):455-63. Ejection fraction response to upright exercise in hypertension: relation to loading conditions and to contractility. Melin JA, Wijns W, Pouleur H, Robert A, Nannan M, De Coster PM, Beckers C, Detry JM. Int J Cardiol. 1987 Oct;17(1):37-49. Metabolic and ultrastructural abnormalities during ischemia in canine myocardium: noninvasive assessment by positron emission tomography. Schwaiger M, Fishbein MC, Block M, Wijns W, Selin C, Phelps ME, Schelbert HR. J Mol Cell Cardiol. 1987 Mar;19(3):259-69. [Does a thrombocytopathy really exist in dominant exudative vitreoretinopathy?] Cordonnier M, Wijns W, Bartik M, Verougstraete C. Bull Soc Belge Ophtalmol. 1987;225 Pt 2:79-88. French. No abstract available. Accumulation of polymorphonuclear leukocytes in reperfused ischemic canine myocardium: relation with tissue viability assessed by fluorine-18-2-deoxyglucose uptake. Wijns W, Melin JA, Leners N, Ferrant A, Keyeux A, Rahier J, Cogneau M, Michel C, Bol A, Robert A, et al. J Nucl Med. 1988 Nov;29(11):1826-32. Assessment of thallium-201 redistribution versus glucose uptake as predictors of viability after coronary occlusion and reperfusion. Melin JA, Wijns W, Keyeux A, Gurné O, Cogneau M, Michel C, Bol A, Robert A, Charlier A, Pouleur H. Circulation. 1988 Apr;77(4):927-34. Area-at-risk determination by technetium-99m-hexakis-2-methoxyisobutyl isonitrile in experimental reperfused myocardial infarction. De Coster PM, Wijns W, Cauwe F, Robert A, Beckers C, Melin JA. Circulation. 1990 Dec;82(6):2152-62. Detection of restenosis after successful coronary angioplasty: improved clinical decision making with use of a logistic model combining procedural and follow-up variables. 8
  • Renkin J, Melin J, Robert A, Richelle F, Bachy JL, Col J, Detry JM, Wijns W. J Am Coll Cardiol. 1990 Nov;16(6):1333-40. Reversal of segmental hypokinesis by coronary angioplasty in patients with unstable angina, persistent T wave inversion, and left anterior descending coronary artery stenosis. Additional evidence for myocardial stunning in humans. Renkin J, Wijns W, Ladha Z, Col J. Circulation. 1990 Sep;82(3):913-21. Angiographic evaluation of vasomotor properties of internal mammary arteries before and after coronary artery bypass grafting in men. Hanet C, Wijns W, Decoster P, Pouleur H, Dion R, Rousseau MF. Am J Cardiol. 1990 Apr 1;65(13):918-21. No abstract available. Flow-induced vasomotor response to tachycardia of the human internal mammary artery and saphenous vein grafts late following bypass surgery. Hanet C, Schroeder E, Michel X, Cosyns J, Dion R, Verhelst R, Wijns W. Circulation. 1991 Nov;84(5 Suppl):III268-74. Asynchronous (segmental early) relaxation impairs left ventricular filling in patients with coronary artery disease and normal systolic function. Vanoverschelde JL, Wijns W, Michel X, Cosyns J, Detry JM. J Am Coll Cardiol. 1991 Nov 1;18(5):1251-8. Prevention of restenosis after percutaneous transluminal coronary angioplasty with thromboxane A2-receptor blockade. A randomized, double-blind, placebo-controlled trial. Coronary Artery Restenosis Prevention on Repeated Thromboxane-Antagonism Study (CARPORT). Serruys PW, Rutsch W, Heyndrickx GR, Danchin N, Mast EG, Wijns W, Rensing BJ, Vos J, Stibbe J. Circulation. 1991 Oct;84(4):1568-80. Percutaneous transluminal coronary angioplasty of the left coronary artery in patients with chronic occlusion of the right coronary artery: clinical and functional results. De Bruyne B, Renkin J, Col J, Wijns W. Am Heart J. 1991 Aug;122(2):415-22. Influence of balloon size and stenosis morphology on immediate and delayed elastic recoil after percutaneous transluminal coronary angioplasty. Hanet C, Wijns W, Michel X, Schroeder E. J Am Coll Cardiol. 1991 Aug;18(2):506-11. Dominant exudative vitreoretinopathy: a sporadic case with a normal platelet aggregation study. Cordonnier M, Wijns W, Bartik M, Van Nechel C, Verougstraete C. Int Ophthalmol. 1991 Jul;15(4):223-7. 9
  • Angioplasty of coronary bifurcation stenoses: immediate and long-term results of the protecting branch technique. Renkin J, Wijns W, Hanet C, Michel X, Cosyns J, Col J. Cathet Cardiovasc Diagn. 1991 Mar;22(3):167-73. Impaired left ventricular function in chronic coronary artery disease: distinction between necrotic and viable myocardium. Depré C, Melin J, Wijns W. Acta Clin Belg. 1991;46(1):1-6. No abstract available. Vasomotor response to ergometrine and nitrates of saphenous vein grafts, internal mammary artery grafts, and grafted coronary arteries late after bypass surgery. Hanet C, Robert A, Wijns W. Circulation. 1992 Nov;86(5 Suppl):II210-6. [Minimal hemorrhagic diathesis] Huc N, Wijns W, Droeshout I, Capel P. Rev Med Brux. 1992 Oct;13(8):307-8. French. No abstract available. Hemodynamic and volume correlates of left ventricular diastolic relaxation and filling in patients with aortic stenosis. Vanoverschelde JL, Essamri B, Michel X, Hanet C, Cosyns JR, Detry JM, Wijns W. J Am Coll Cardiol. 1992 Oct;20(4):813-21. Therapeutic dissection after successful coronary balloon angioplasty: no influence on restenosis or on clinical outcome in 693 patients. The MERCATOR Study Group (Multicenter European Research Trial with Cilazapril after Angioplasty to prevent Transluminal Coronary Obstruction and Restenosis). Hermans WR, Rensing BJ, Foley DP, Deckers JW, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW. J Am Coll Cardiol. 1992 Oct;20(4):767-80. One hundred and thirteen attempts at directional coronary atherectomy: the early and combined experience of two European centres using quantitative angiography to assess their results. Umans V, Haine E, Renkin J, de Feyter P, Wijns W, Serruys PW. Eur Heart J. 1992 Jul;13(7):918-24. [Anti-phospholipid antibodies and recurrent miscarriage] Capel P, Lambrechts A, Wijns W, Collard C. Rev Med Brux. 1992 Apr;13(4):113-6. French. 10
  • Stenting of venous bypass grafts: a new treatment modality for patients who are poor candidates for reintervention. de Scheerder IK, Strauss BH, de Feyter PJ, Beatt KJ, Baur LH, Wijns W, Heyndrix GR, Suryapranata H, van den Brand M, Buis B, et al. Am Heart J. 1992 Apr;123(4 Pt 1):1046-54. Regional oxidative metabolism in patients after recovery from reperfused anterior myocardial infarction. Relation to regional blood flow and glucose uptake. Vanoverschelde JL, Melin JA, Bol A, Vanbutsele R, Cogneau M, Labar D, Robert A, Michel C, Wijns W. Circulation. 1992 Jan;85(1):9-21. Hemodynamic and mechanical determinants of myocardial O2 consumption in normal human heart: effects of dobutamine. Vanoverschelde JL, Wijns W, Essamri B, Bol A, Robert A, Labar D, Cogneau M, Michel C, Melin JA. Am J Physiol. 1993 Dec;265(6 Pt 2):H1884-92. Luminal narrowing after percutaneous transluminal coronary angioplasty. A study of clinical, procedural, and lesional factors related to long-term angiographic outcome. Coronary Artery Restenosis Prevention on Repeated Thromboxane Antagonism (CARPORT) Study Group. Rensing BJ, Hermans WR, Vos J, Tijssen JG, Rutch W, Danchin N, Heyndrickx GR, Mast EG, Wijns W, Serruys PW. Circulation. 1993 Sep;88(3):975-85. Effects of D-nebivolol and L-nebivolol on left ventricular systolic and diastolic function: comparison with D-L-nebivolol and atenolol. Stoleru L, Wijns W, van Eyll C, Bouvy T, Van Nueten L, Pouleur H. J Cardiovasc Pharmacol. 1993 Aug;22(2):183-90. Optimal use of dobutamine stress for the detection and evaluation of coronary artery disease: combination with echocardiography or scintigraphy, or both? Marwick T, D'Hondt AM, Baudhuin T, Willemart B, Wijns W, Detry JM, Melin J. J Am Coll Cardiol. 1993 Jul;22(1):159-67. Regional wall motion abnormalities in stunned and hibernating myocardium. Heyndrickx GR, Wijns W, Melin JA. Eur Heart J. 1993 Jul;14 Suppl A:8-13. Review. Absence of detectable delayed elastic recoil 24 hours after percutaneous transluminal coronary angioplasty. Hanet C, Michel X, Schroeder E, Wijns W. Am J Cardiol. 1993 Jun 15;71(16):1433-6. No abstract available. 11
  • Diagnosis of coronary artery disease in elderly patients: safety and efficacy of dobutamine echocardiography. Baudhuin T, Marwick T, Melin J, Wijns W, D'Hondt AM, Detry JM. Eur Heart J. 1993 Jun;14(6):799-803. Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium. Vanoverschelde JL, Wijns W, Depré C, Essamri B, Heyndrickx GR, Borgers M, Bol A, Melin JA. Circulation. 1993 May;87(5):1513-23. The mechanism of directional coronary atherectomy. Umans VA, Haine E, Renkin J, de Feyter PJ, Wijns W, Serruys PW. Eur Heart J. 1993 Apr;14(4):505-10. Recovery of regional contractile function and oxidative metabolism in stunned myocardium induced by 1-hour circumflex coronary artery stenosis in chronically instrumented dogs. Heyndrickx GR, Wijns W, Vogelaers D, Degrieck Y, Bol A, Vandeplassche G, Melin JA. Circ Res. 1993 Apr;72(4):901-13. Competition between palmitate and ketone bodies as fuels for the heart: study with positron emission tomography. Vanoverschelde JL, Wijns W, Kolanowski J, Bol A, Decoster PM, Michel C, Cogneau M, Heyndrickx GR, Essamri B, Melin JA. Am J Physiol. 1993 Mar;264(3 Pt 2):H701-7. Selection of the optimal nonexercise stress for the evaluation of ischemic regional myocardial dysfunction and malperfusion. Comparison of dobutamine and adenosine using echocardiography and 99mTc-MIBI single photon emission computed tomography. Marwick T, Willemart B, D'Hondt AM, Baudhuin T, Wijns W, Detry JM, Melin J. Circulation. 1993 Feb;87(2):345-54. Patient, lesion, and procedural variables as risk factors for luminal re-narrowing after successful coronary angioplasty: a quantitative analysis in 653 patients with 778 lesions. Multicenter European Research Trial with Cilazapril after Angioplasty to prevent Transluminal Coronary Obstruction and Restenosis (MERCATOR) Study Group. Hermans WR, Rensing BJ, Foley DP, Tijssen JG, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW. J Cardiovasc Pharmacol. 1993;22 Suppl 4:S45-57. How accurate is dobutamine stress electrocardiography for detection of coronary artery disease? Comparison with two-dimensional echocardiography and technetium-99m methoxyl isobutyl isonitrile (mibi) perfusion scintigraphy. 12
  • Mairesse GH, Marwick TH, Vanoverschelde JL, Baudhuin T, Wijns W, Melin JA, Detry JM. J Am Coll Cardiol. 1994 Oct;24(4):920-7. On-line quantification of left ventricular volumes and ejection fraction by automated backscatter imaging-assisted boundary detection: comparison with contrast cineventriculography. Vanoverschelde JL, Hanet C, Wijns W, Detry JM. Am J Cardiol. 1994 Sep 15;74(6):633-5. No abstract available. Comparative ability of dobutamine and exercise stress in inducing myocardial ischaemia in active patients. Marwick TH, D'Hondt AM, Mairesse GH, Baudhuin T, Wijns W, Detry JM, Melin JA. Br Heart J. 1994 Jul;72(1):31-8. Erratum in: Br Heart J 1994 Dec;72(6):590. Relation between myocardial blood flow and the severity of coronary-artery stenosis. Uren NG, Melin JA, De Bruyne B, Wijns W, Baudhuin T, Camici PG. N Engl J Med. 1994 Jun 23;330(25):1782-8. Assessment of left ventricular dysfunction by nuclear cardiology. Melin JA, Wijns W, Vanoverschelde JL, Heyndrickx GR. Cardiovasc Drugs Ther. 1994 May;8 Suppl 2:381-92. Review. The use of carbon 11-labeled acetate for assessment of aerobic metabolism. Melin JA, Vanoverschelde JL, Bol A, Heyndrickx G, Wijns W. J Nucl Cardiol. 1994 Mar-Apr;1(2 Pt 2):S48-57. Review. Coronary flow reserve calculated from pressure measurements in humans. Validation with positron emission tomography. De Bruyne B, Baudhuin T, Melin JA, Pijls NH, Sys SU, Bol A, Paulus WJ, Heyndrickx GR, Wijns W. Circulation. 1994 Mar;89(3):1013-22. Clinical, histologic and quantitative angiographic predictors of restenosis after directional coronary atherectomy: a multivariate analysis of the renarrowing process and late outcome. Umans VA, Robert A, Foley D, Wijns W, Haine E, de Feyter PJ, Serruys PW. J Am Coll Cardiol. 1994 Jan;23(1):49-58. Preoperative selection of patients with severely impaired left ventricular function for coronary revascularization. Role of low-dose dobutamine echocardiography and exercise- redistribution-reinjection thallium SPECT. Vanoverschelde JL, Gerber BL, D'Hondt AM, De Kock M, Dion R, Wijns W, Melin JA. Circulation. 1995 Nov 1;92(9 Suppl):II37-44. 13
  • Effect of aging on myocardial perfusion reserve. Uren NG, Camici PG, Melin JA, Bol A, de Bruyne B, Radvan J, Olivotto I, Rosen SD, Impallomeni M, Wijns W. J Nucl Med. 1995 Nov;36(11):2032-6. Restenosis after coronary interventions and device specificity. Wijns W. Eur Heart J. 1995 Oct;16(10):1307-8. No abstract available. Delineation of myocardial viability with PET. Grandin C, Wijns W, Melin JA, Bol A, Robert AR, Heyndrickx GR, Michel C, Vanoverschelde JL. J Nucl Med. 1995 Sep;36(9):1543-52. Structural and metabolic correlates of the reversibility of chronic left ventricular ischemic dysfunction in humans. Depré C, Vanoverschelde JL, Melin JA, Borgers M, Bol A, Ausma J, Dion R, Wijns W. Am J Physiol. 1995 Mar;268(3 Pt 2):H1265-75. Noninvasive estimation of pulmonary arterial wedge pressure with Doppler transmitral flow velocity pattern in patients with known heart disease. Vanoverschelde JL, Robert AR, Gerbaux A, Michel X, Hanet C, Wijns W. Am J Cardiol. 1995 Feb 15;75(5):383-9. Exercise gated planar myocardial perfusion imaging using technetium-99m sestamibi for the diagnosis of coronary artery disease: an alternative to exercise tomographic imaging. Jamar F, Topcuoglu R, Cauwe F, De Coster P, Roelants V, Beckers C, Wijns W, Melin JA. Eur J Nucl Med. 1995 Jan;22(1):40-8. Neovascularization in human coronary atherosclerotic lesions. Depré C, Havaux X, Wijns W. Cathet Cardiovasc Diagn. 1996 Nov;39(3):215-20. Simultaneous coronary pressure and flow velocity measurements in humans. Feasibility, reproducibility, and hemodynamic dependence of coronary flow velocity reserve, hyperemic flow versus pressure slope index, and fractional flow reserve. de Bruyne B, Bartunek J, Sys SU, Pijls NH, Heyndrickx GR, Wijns W. Circulation. 1996 Oct 15;94(8):1842-9. Interventional cardiology in Europe 1993. Working Group on Coronary Circulation of the European Society of Cardiology. Meyer BJ, Meier B, Bonzel T, Fabian J, Heyndrickx G, Morice MC, Mühlberger V, Piscione F, Rothman M, Wijns W, van den Brand M. Eur Heart J. 1996 Sep;17(9):1318-28. 14
  • Myocardial blood flow, glucose uptake, and recruitment of inotropic reserve in chronic left ventricular ischemic dysfunction. Implications for the pathophysiology of chronic myocardial hibernation. Gerber BL, Vanoverschelde JL, Bol A, Michel C, Labar D, Wijns W, Melin JA. Circulation. 1996 Aug 15;94(4):651-9. Head-to-head comparison of exercise-redistribution-reinjection thallium single-photon emission computed tomography and low dose dobutamine echocardiography for prediction of reversibility of chronic left ventricular ischemic dysfunction. Vanoverschelde JL, D'Hondt AM, Marwick T, Gerber BL, De Kock M, Dion R, Wijns W, Melin JA. J Am Coll Cardiol. 1996 Aug;28(2):432-42. Continued benefit of coronary stenting versus balloon angioplasty: one-year clinical follow-up of Benestent trial. Benestent Study Group. Macaya C, Serruys PW, Ruygrok P, Suryapranata H, Mast G, Klugmann S, Urban P, den Heijer P, Koch K, Simon R, Morice MC, Crean P, Bonnier H, Wijns W, Danchin N, Bourdonnec C, Morel MA. J Am Coll Cardiol. 1996 Feb;27(2):255-61. Tachycardiomyopathy: mechanisms and clinical implications. Fenelon G, Wijns W, Andries E, Brugada P. Pacing Clin Electrophysiol. 1996 Jan;19(1):95-106. Review. No abstract available. The impact of myocardial blood flow quantitation with PET on the understanding of cardiac diseases. Camici PG, Gropler RJ, Jones T, L'Abbate A, Maseri A, Melin JA, Merlet P, Parodi O, Schelbert HR, Schwaiger M, Wijns W. Eur Heart J. 1996 Jan;17(1):25-34. Review. No abstract available. Pathophysiological mechanisms of chronic reversible left ventricular dysfunction due to coronary artery disease (hibernating myocardium). Camici PG, Wijns W, Borgers M, De Silva R, Ferrari R, Knuuti J, Lammertsma AA, Liedtke AJ, Paternostro G, Vatner SF. Circulation. 1997 Nov 4;96(9):3205-14. Review. No abstract available. Clinical and Angiographic Results with the Multi-Linkª Coronary Stent System Ñ The West European Stent Trial (WEST). Emanuelsson H, Serruys PW, van Der Giessen WJ, Dawkins K, Rutsch W, Katus H, Morel MA, Veldhof S, Wijns W, Sigwart U. J Invasive Cardiol. 1997 Nov;9(9):561-568. Accuracy of currently available techniques for prediction of functional recovery after revascularization in patients with left ventricular dysfunction due to chronic coronary artery disease: comparison of pooled data. Bax JJ, Wijns W, Cornel JH, Visser FC, Boersma E, Fioretti PM. 15
  • J Am Coll Cardiol. 1997 Nov 15;30(6):1451-60. Recommendations on stent manufacture, implantation and utilization. Study Group of the Working Group on Coronary Circulation. Balcon R, Beyar R, Chierchia S, De Scheerder I, Hugenholtz PG, Kiemeneij F, Meier B, Meyer J, Monassier JP, Wijns W. Eur Heart J. 1997 Oct;18(10):1536-47. Review. No abstract available. Pathology of unstable plaque: correlation with the clinical severity of acute coronary syndromes. Depré C, Wijns W, Robert AM, Renkin JP, Havaux X. J Am Coll Cardiol. 1997 Sep;30(3):694-702. The value of quantitative myocardial perfusion imaging with positron emission tomography in coronary artery disease. Wijns W, Camici PG. Herz. 1997 Apr;22(2):87-95. Review. Chronic myocardial hibernation in humans. From bedside to bench. Vanoverschelde JL, Wijns W, Borgers M, Heyndrickx G, Depré C, Flameng W, Melin JA. Circulation. 1997 Apr 1;95(7):1961-71. Review. No abstract available. BWGIC guidelines for training and quality control in adult interventional cardiology. Belgian Working Group of Invasive Cardiology. Legrand V, Vrolix M, De Bruyne B, Wijns W, Heyndrickx G, De Scheerder I, Taeymans Y, Vrints C, Materne P, Benit E, Col J, Boland J, De Keyser JM, Lafontaine P, Renkin J. Acta Cardiol. 1997;52(6):507-14. No abstract available. Fluorine-18-fluorodeoxyglucose cardiac imaging using a modified scintillation camera. Sandler MP, Bax JJ, Patton JA, Visser FC, Martin WH, Wijns W. J Nucl Med. 1998 Dec;39(12):2035-43. Review. Evaluation of two D-Dimer assays in the diagnosis of venous thromboembolism. Wijns W, Daoud N, Droeshout I, Pradier O, Wautrecht JC, Golzarian J, Capel P. Acta Clin Belg. 1998 Aug;53(4):270-4. Pathology of restenosis in saphenous bypass grafts after long-term stent implantation. Depre C, Havaux X, Wijns W. Am J Clin Pathol. 1998 Sep;110(3):378-84. Hibernating myocardium. Wijns W, Vatner SF, Camici PG. N Engl J Med. 1998 Jul 16;339(3):173-81. Review. No abstract available. 16
  • Long-term follow-up after deferral of percutaneous transluminal coronary angioplasty of intermediate stenosis on the basis of coronary pressure measurement. Bech GJ, De Bruyne B, Bonnier HJ, Bartunek J, Wijns W, Peels K, Heyndrickx GR, Koolen JJ, Pijls NH. J Am Coll Cardiol. 1998 Mar 15;31(4):841-7. Interventional cardiology in Europe 1994. Working Group Coronary Circulation of the European Society of Cardiology. Windecker S, Meyer BJ, Bonzel T, Fabian J, Heyndrickx G, Morice MC, Mühlberger V, Piscione F, Rothman M, Wijns W, van den Brand M, Meier B. Eur Heart J. 1998 Jan;19(1):40-54. Clinical and Angiographic Results with the Multi-Linkª Coronary Stent System Ñ The West European Stent Trial (WEST). Emanuelsson H, Serruys PW, van Der Giessen WJ, Dawkins K, Rutsch W, Katus H, Morel MA, Veldhof S, Wijns W, Sigwart U. J Invasive Cardiol. 1998 Apr;10 Suppl B:12B-19B. Myocardial perfusion and oxygen consumption in reperfused noninfarcted dysfunctional myocardium after unstable angina: direct evidence for myocardial stunning in humans. Gerber BL, Wijns W, Vanoverschelde JL, Heyndrickx GR, De Bruyne B, Bartunek J, Melin JA. J Am Coll Cardiol. 1999 Dec;34(7):1939-46. Fluorodeoxyglucose imaging to assess myocardial viability: PET, SPECT or gamma camera coincidence imaging? Bax JJ, Wijns W. J Nucl Med. 1999 Nov;40(11):1893-5. No abstract available. Effects of dobutamine on coronary stenosis physiology and morphology: comparison with intracoronary adenosine. Bartunek J, Wijns W, Heyndrickx GR, de Bruyne B. Circulation. 1999 Jul 20;100(3):243-9. Indications for intracoronary stent placement: the european view. Working Group on Coronary Circulation of the European Society of Cardiology. Eeckhout E, Wijns W, Meier B, Goy JJ. Eur Heart J. 1999 Jul;20(14):1014-9. Interventional cardiology in Europe 1995. Working Group Coronary Circulation of the European Society of Cardiology. Windecker S, Maier-Rudolph W, Bonzel T, Heyndrickx G, Lablanche JM, Morice MC, Mühlberger V, Neuhaus KL, Piscione F, van den Brand M, Wijns W, Meier B. Eur Heart J. 1999 Apr;20(7):484-95. No abstract available. 17
  • Expression of inducible nitric oxide synthase in human coronary atherosclerotic plaque. Depre C, Havaux X, Renkin J, Vanoverschelde JL, Wijns W. Cardiovasc Res. 1999 Feb;41(2):465-72. Carvedilol for prevention of restenosis after directional coronary atherectomy : final results of the European carvedilol atherectomy restenosis (EUROCARE) trial. Serruys PW, Foley DP, Höfling B, Puel J, Glogar HD, Seabra-Gomes R, Goicolea J, Coste P, Rutsch W, Katus H, Bonnier H, Wijns W, Betriu A, Hauf-Zachariou U, van Swijndregt EM, Melkert R, Simon R. Circulation. 2000 Apr 4;101(13):1512-8. Morphological analysis of atherosclerotic plaque retrieved by coronary atherectomy. Depré C, Ribichini F, Wijns W. Semin Interv Cardiol. 2000 Dec;5(4):175-84. Review. Methodological and clinical implications of the relocation of the minimal luminal diameter after intracoronary radiation therapy. Dose Finding Study Group. Sabaté M, Costa MA, Kozuma K, Kay IP, van der Wiel CJ, Verin V, Wijns W, Serruys PW. J Am Coll Cardiol. 2000 Nov 1;36(5):1536-41. CRP: does it stand for C oronary R estenosis P rediction? Wijns W, Ribichini F. Eur Heart J. 2000 Jul;21(14):1121-3. Review. No abstract available. Time course of functional recovery after coronary artery bypass graft surgery in patients with chronic left ventricular ischemic dysfunction. Vanoverschelde JL, Depré C, Gerber BL, Borgers M, Wijns W, Robert A, Dion R, Melin JA. Am J Cardiol. 2000 Jun 15;85(12):1432-9. Multicenter evaluation of the phosphorylcholine-coated biodivYsio stent in short de novo coronary lesions: The SOPHOS study. Boland JL, Corbeij HA, Van Der Giessen W, Seabra-Gomes R, Suryapranata H, Wijns W, Hanet C, Suttorp MJ, Buller C, Bonnier JJ, Colombo A, Van Birgelen C, Pieper M, Mangioni JA, Londero H, Carere RG, Hamm CW, Bonan R, Bartorelli A, Kyriakides ZS, Chauhan A, Rothman M, Grinfeld L, Oosterwijk C, Serruys PW, Cumberland DC. Int J Cardiovasc Intervent. 2000 Dec;3(4):215-225. Endoluminal beta-radiation therapy for the prevention of coronary restenosis after balloon angioplasty. The Dose-Finding Study Group. Verin V, Popowski Y, de Bruyne B, Baumgart D, Sauerwein W, Lins M, Kovacs G, Thomas M, Calman F, Disco C, Serruys PW, Wijns W; Dose-Finding Study Group. N Engl J Med. 2001 Jan 25;344(4):243-9. 18
  • Angiographic and clinical one-year follow-up of the Cordis tantalum coil stent in a multicenter international study demonstrating improved restenosis rates when compared to pooled PTCA and BENESTENT-I data: the European Antiplatelet Stent Investigation (EASI). Rothman M, Serruys P, Grollier G, Hoorntje J, van Den Bos A, Wijns W, Gershlick A, Van Es G, Melkert R, Eijgelshoven M, Lenderink T, Richardson G, Dille-Amo C; European Antiplatelet Stent Investigation. Catheter Cardiovasc Interv. 2001 Feb;52(2):249-59. Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but "Normal" coronary angiography. De Bruyne B, Hersbach F, Pijls NH, Bartunek J, Bech JW, Heyndrickx GR, Gould KL, Wijns W. Circulation. 2001 Nov 13;104(20):2401-6. Clinical and quantitative coronary angiographic predictors of coronary restenosis: a comparative analysis from the balloon-to-stent era. Mercado N, Boersma E, Wijns W, Gersh BJ, Morillo CA, de Valk V, van Es GA, Grobbee DE, Serruys PW. J Am Coll Cardiol. 2001 Sep;38(3):645-52. Positron emission tomography using(18)F-fluoro-deoxyglucose and euglycaemic hyperinsulinaemic glucose clamp: optimal criteria for the prediction of recovery of post- ischaemic left ventricular dysfunction. Results from the European Community Concerted Action Multicenter study on use of(18)F-fluoro-deoxyglucose Positron Emission Tomography for the Detection of Myocardial Viability. Gerber BL, Ordoubadi FF, Wijns W, Vanoverschelde JL, Knuuti MJ, Janier M, Melon P, Blanksma PK, Bol A, Bax JJ, Melin JA, Camici PG. Eur Heart J. 2001 Sep;22(18):1691-701. The influence of stent length on clinical and angiographic outcome in patients undergoing elective stenting for native coronary artery lesions; final results of the Magic 5L Study. Foley DP, Pieper M, Wijns W, Suryapranata H, Grollier G, Legrand V, de Scheerder I, Hanet C, Puel J, Mudra H, Bonnier HJ, Colombo A, Thomas M, Probst P, Morice M, Kleijne J, Serruys PW; MAGIC 5L investigators. Eur Heart J. 2001 Sep;22(17):1585-93. Fractional flow reserve in patients with prior myocardial infarction. De Bruyne B, Pijls NH, Bartunek J, Kulecki K, Bech JW, De Winter H, Van Crombrugge P, Heyndrickx GR, Wijns W. Circulation. 2001 Jul 10;104(2):157-62. Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: a randomized trial. Bech GJ, De Bruyne B, Pijls NH, de Muinck ED, Hoorntje JC, Escaned J, Stella PR, Boersma E, Bartunek J, Koolen JJ, Wijns W. 19
  • Circulation. 2001 Jun 19;103(24):2928-34. The European registry of cardiac catheter interventions 1996. Maier W, Windecker S, Lablanche JM, Mühlberger V, Wijns W, Meier B; Working group Coronary Circulation of the European Society of Cardiology. Eur Heart J. 2001 Mar;22(5):373-7. No abstract available. Occurrence of the Asn45Ser mutation in the GPIX gene in a Belgian patient with Bernard Soulier syndrome. Vanhoorelbeke K, Schlammadinger A, Delville JP, Handsaeme J, Vandecasteele G, Vauterin S, Pradier O, Wijns W, Deckmyn H. Platelets. 2001 Mar;12(2):114-20. Angiographic analysis of the angioplasty versus rotational atherectomy for the treatment of diffuse in-stent restenosis trial (ARTIST). Dietz U, Rupprecht HJ, de Belder MA, Wijns W, Quarles van Ufford MA, Klues HG, vom Dahl J. Am J Cardiol. 2002 Oct 15;90(8):843-7. Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): sirolimus-eluting stents inhibit restenosis irrespective of the vessel size. Regar E, Serruys PW, Bode C, Holubarsch C, Guermonprez JL, Wijns W, Bartorelli A, Constantini C, Degertekin M, Tanabe K, Disco C, Wuelfert E, Morice MC; RAVEL Study Group. Circulation. 2002 Oct 8;106(15):1949-56. Can ACE Inhibitors Promote Detrimental Vascular Effects After Percutaneous Injury? Ribichini F, Ferrero V, Wijns W, Matullo G, Piazza A, Uslenghi E. Hypertension. 2002 Oct;40(4):e5-6; author reply e5-6. No abstract available. Intracoronary beta-radiation to reduce restenosis after balloon angioplasty and stenting; the Beta Radiation In Europe (BRIE) study. Serruys PW, Sianos G, van der Giessen W, Bonnier HJ, Urban P, Wijns W, Benit E, Vandormael M, Dörr R, Disco C, Debbas N, Silber S; BRIE study group. Eur Heart J. 2002 Sep;23(17):1351-9. Acute myocardial infarction: reperfusion treatment. Ribichini F, Wijns W. Heart. 2002 Sep;88(3):298-305. Review. No abstract available. Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial. Serruys PW, Degertekin M, Tanabe K, Abizaid A, Sousa JE, Colombo A, Guagliumi G, Wijns W, Lindeboom WK, Ligthart J, de Feyter PJ, Morice MC; RAVEL Study Group. 20
  • Circulation. 2002 Aug 13;106(7):798-803. Dose distributions for 90Y intravascular brachytherapy sources used with balloon catheters. Piessens M, Reynaert N, Potempa J, Thierens H, Wijns W, Verbeke L. Med Phys. 2002 Jul;29(7):1562-71. Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction. Bax JJ, Fath-Ordoubadi F, Boersma E, Wijns W, Camici PG. Eur J Nucl Med Mol Imaging. 2002 Jun;29(6):721-7. Epub 2002 Apr 10. Haptoglobin phenotype and the risk of restenosis after coronary artery stent implantation. Roguin A, Ribichini F, Ferrero V, Matullo G, Herer P, Wijns W, Levy AP. Am J Cardiol. 2002 Apr 1;89(7):806-10. The effect of completeness of revascularization on event-free survival at one year in the ARTS trial. van den Brand MJ, Rensing BJ, Morel MA, Foley DP, de Valk V, Breeman A, Suryapranata H, Haalebos MM, Wijns W, Wellens F, Balcon R, Magee P, Ribeiro E, Buffolo E, Unger F, Serruys PW. J Am Coll Cardiol. 2002 Feb 20;39(4):559-64. Angiographical follow-up after radioactive "Cold Ends" stent implantation: a multicenter trial. Wardeh AJ, Albiero R, Kay IP, Knook AH, Wijns W, Kozuma K, Nishida T, Ferrero V, Levendag PC, van Der Giessen WJ, Colombo A, Serruys PW. Circulation. 2002 Feb 5;105(5):550-3. A randomized comparison of the value of additional stenting after optimal balloon angioplasty for long coronary lesions: final results of the additional value of NIR stents for treatment of long coronary lesions (ADVANCE) study. Serruys PW, Foley DP, Suttorp MJ, Rensing BJ, Suryapranata H, Materne P, van den Bos A, Benit E, Anzuini A, Rutsch W, Legrand V, Dawkins K, Cobaugh M, Bressers M, Backx B, Wijns W, Colombo A. J Am Coll Cardiol. 2002 Feb 6;39(3):393-9. The European Registry of Cardiac Catheter Interventions 1997. Maier W, Camici P, Windecker S, Pfiffner D, Wijns W, Meier B; Working Group Coronary Circulation of the European Society of Cardiology. Eur Heart J. 2002 Dec;23(24):1903-7. No abstract available. Geographical miss and restenosis during catheter-based intracoronary beta-radiation for de novo lesions. Sianos G, Wijns W, de Feyter PJ, van Domburg R, Serruys PW. 21
  • Cardiovasc Radiat Med. 2002 Jul-Dec;3(3-4):138-46. [The immunology-hematology-transfusion department] Goldman M, Andrien M, Delville JP, Dupont E, Kornreich A, Lambermont M, Ocmant A, Schandené L, Mascart F, Pradier O, Stordeur P, Toungouz M, Wijns W. Rev Med Brux. 2002;23 Suppl 2:87-91. Review. French. Management of acute myocardial infarction in patients presenting with ST-segment elevation. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Van de Werf F, Ardissino D, Betriu A, Cokkinos DV, Falk E, Fox KA, Julian D, Lengyel M, Neumann FJ, Ruzyllo W, Thygesen C, Underwood SR, Vahanian A, Verheugt FW, Wijns W; Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J. 2003 Jan;24(1):28-66. No abstract available. Effect of angiotensin-converting enzyme inhibition on restenosis after coronary stenting. Ribichini F, Wijns W, Ferrero V, Matullo G, Camilla T, Feola M, Guarrera S, Vado A, Piazza A, Uslenghi E. Am J Cardiol. 2003 Jan 15;91(2):154-8. Direct stent implantation using the EXPRESS Coronary Stent System: results of a multi- center feasibility study. Silber S, Grube E, Marco J, Grollier G, Morice MC, Serruys P, Cobaugh M, Wijns W. J Interv Cardiol. 2003 Dec;16(6):491-7. Geographical miss during centered intracoronary beta-radiation with 90Yttrium: incidence and implications for recurrence rates after vascular brachytherapy for de novo lesions. Sianos G, Wijns W, de Feyter PJ, Serruys PW. Int J Cardiovasc Intervent. 2003;5(4):181-9. Effects of intravenous dobutamine on coronary vasomotion in humans. Barbato E, Bartunek J, Wyffels E, Wijns W, Heyndrickx GR, De Bruyne B. J Am Coll Cardiol. 2003 Nov 5;42(9):1596-601. Estrogen receptor-alpha polymorphisms and angiographic outcome after coronary artery stenting. Ferrero V, Ribichini F, Matullo G, Guarrera S, Carturan S, Vado A, Vassanelli C, Piazza A, Uslenghi E, Wijns W. Arterioscler Thromb Vasc Biol. 2003 Dec;23(12):2223-8. Epub 2003 Oct 16. Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS). Schofer J, Schlüter M, Gershlick AH, Wijns W, Garcia E, Schampaert E, Breithardt G; E-SIRIUS Investigators. 22
  • Lancet. 2003 Oct 4;362(9390):1093-9. Guidelines for percutaneous coronary intervention by the Belgian Working Group on Invasive Cardiology. Legrand V, Wijns W, Vandenbranden F, Benit E, Boland J, Claeys M, De Scheerder I, Eemans T, Hanet C, Heyndrickx G, Lafontaine P, Materne P, Taeymans Y, Vrints C, Vrolix M; Belgian Working Group on Invasive Cardiology. Acta Cardiol. 2003 Aug;58(4):341-8. No abstract available. Clinical and angiographic acute and follow up results of intracoronary beta brachytherapy in saphenous vein bypass grafts: a subgroup analysis of the multicentre European registry of intraluminal coronary beta brachytherapy (RENO). Schiele TM, Regar E, Silber S, Eeckhout E, Baumgart D, Wijns W, Colombo A, Rutsch W, Meerkin D, Gershlick A, Bonan R, Urban P; RENO Investigators. Heart. 2003 Jun;89(6):640-4. Erratum in: Heart. 2003 Jul;89(7):792. Intracoronary and intravenous adenosine 5'-triphosphate, adenosine, papaverine, and contrast medium to assess fractional flow reserve in humans. De Bruyne B, Pijls NH, Barbato E, Bartunek J, Bech JW, Wijns W, Heyndrickx GR. Circulation. 2003 Apr 15;107(14):1877-83. Epub 2003 Mar 31. Images in cardiovascular medicine. Non-life-threatening leaflet escape. Casselman F, Heyndrickx G, Wijns W, Hendrickx J, Vanermen H. Circulation. 2003 Mar 25;107(11):e72. No abstract available. Clinical and angiographic outcome of patients with mild coronary lesions treated with balloon angioplasty or coronary stenting. Implications for mechanical plaque sealing. Mercado N, Maier W, Boersma E, Bucher C, de Valk V, O'Neill WW, Gersh BJ, Meier B, Serruys PW, Wijns W. Eur Heart J. 2003 Mar;24(6):541-51. Direct stenting. Barbato E, Marco J, Wijns W. Eur Heart J. 2003 Mar;24(5):394-403. Review. DECOPI (DEsobstruction COronaire en Post-Infarctus): a randomized multi-centre trial of occluded artery angioplasty after acute myocardial infarction. Steg PG, Thuaire C, Himbert D, Carrié D, Champagne S, Coisne D, Khalifé K, Cazaux P, Logeart D, Slama M, Spaulding C, Cohen A, Tirouvanziam A, Montély JM, Rodriguez RM, Garbarz E, Wijns W, Durand-Zaleski I, Porcher R, Brucker L, Chevret S, Chastang C; DECOPI Investigators. Eur Heart J. 2004 Dec;25(24):2187-94. Reperfusion treatment of ST-elevation acute myocardial infarction. Ribichini F, Ferrero V, Wijns W. 23
  • Prog Cardiovasc Dis. 2004 Sep-Oct;47(2):131-57. Review. Alpha-adrenergic receptor blockade and hyperaemic response in patients with intermediate coronary stenoses. Barbato E, Bartunek J, Aarnoudse W, Vanderheyden M, Staelens F, Wijns W, Heyndrickx GR, Pijls NH, De Bruyne B. Eur Heart J. 2004 Nov;25(22):2034-9. Angiographic and three-dimensional intravascular ultrasound analysis of combined intracoronary beta radiation and self-expanding stent implantation in human coronary arteries. Ferrero V, Ribichini F, Heyndrickx GR, De Bruyne B, Piessens M, Carlier S, Büchi M, Matullo G, Vassanelli C, Wijns W. Am J Cardiol. 2004 Nov 15;94(10):1237-42. Long-term patency of internal mammary artery bypass grafts: relationship with preoperative severity of the native coronary artery stenosis. Berger A, MacCarthy PA, Siebert U, Carlier S, Wijns W, Heyndrickx G, Bartunek J, Vanermen H, De Bruyne B. Circulation. 2004 Sep 14;110(11 Suppl 1):II36-40. Direct stenting versus direct stenting followed by centered beta-radiation with intravascular ultrasound-guided dosimetry and long-term anti-platelet treatment: results of a randomized trial: Beta-Radiation Investigation with Direct Stenting and Galileo in Europe (BRIDGE). Serruys PW, Wijns W, Sianos G, de Scheerder I, van den Heuvel PA, Rutsch W, Glogar HD, Macaya C, Materne PH, Veldhof S, Vonhausen H, Otto-Terlouw PC, van der Giessen WJ. J Am Coll Cardiol. 2004 Aug 4;44(3):528-37. [The e-Cypher registry: objectives and organization] Urban P, Gerschlick AH, Guagliumi G, Guyon P, Lotan C, Schofer J, Seth A, Sousa JE, Wijns W; Investigateurs de e-Cypher. Ann Cardiol Angeiol (Paris). 2004 May;53 Suppl 1:18s-21s. French. No abstract available. Identification of hibernating myocardium by acoustic microscopy. Ng DW, Sathish S, Khan A, Chandrasoma P, Wijns W, Chandraratna PA. Ultrasound Med Biol. 2004 May;30(5):693-6. Imaging techniques for the assessment of myocardial hibernation. Report of a Study Group of the European Society of Cardiology. Underwood SR, Bax JJ, vom Dahl J, Henein MY, Knuuti J, van Rossum AC, Schwarz ER, Vanoverschelde JL, van der Wall EE, Wijns W; Study Group of the European Society of Cardiology. 24
  • Eur Heart J. 2004 May;25(10):815-36. Review. Erratum in: Eur Heart J. 2004 Dec;25(23):2176. Tissue doppler imaging predicts recovery of left ventricular function after recanalization of an occluded coronary artery. Penicka M, Bartunek J, Wijns W, De Wolf I, Heyndrickx GR, De Raedt H, Barbato E, De Bruyne B. J Am Coll Cardiol. 2004 Jan 7;43(1):85-91. Incidence of stent under-deployment as a cause of in-stent restenosis in long stents: take your lesson! Wijns W. Int J Cardiovasc Imaging. 2004 Dec;20(6):529-30. No abstract available. Management and outcome of patients with established coronary artery disease: the Euro Heart Survey on coronary revascularization. Lenzen MJ, Boersma E, Bertrand ME, Maier W, Moris C, Piscione F, Sechtem U, Stahle E, Widimsky P, de Jaegere P, Scholte op Reimer WJ, Mercado N, Wijns W; European Society of Cardiology. Eur Heart J. 2005 Jun;26(12):1169-79. Epub 2005 Mar 31. Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Silber S, Albertsson P, Avilés FF, Camici PG, Colombo A, Hamm C, Jørgensen E, Marco J, Nordrehaug JE, Ruzyllo W, Urban P, Stone GW, Wijns W; Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Eur Heart J. 2005 Apr;26(8):804-47. Epub 2005 Mar 15. Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three- year results of the RAVEL trial. Fajadet J, Morice MC, Bode C, Barragan P, Serruys PW, Wijns W, Constantini CR, Guermonprez JL, Eltchaninoff H, Blanchard D, Bartorelli A, Laarman GJ, Perin M, Sousa JE, Schuler G, Molnar F, Guagliumi G, Colombo A, Ban Hayashi E, Wülfert E. Circulation. 2005 Mar 1;111(8):1040-4. Epub 2005 Feb 21. Impact of body mass index on the outcome of patients with multivessel disease randomized to either coronary artery bypass grafting or stenting in the ARTS trial: The obesity paradox II? Gruberg L, Mercado N, Milo S, Boersma E, Disco C, van Es GA, Lemos PA, Ben Tzvi M, Wijns W, Unger F, Beyar R, Serruys PW; Arterial Revascularization Therapies Study Investigators. Am J Cardiol. 2005 Feb 15;95(4):439-44. Pressure-derived measurement of coronary flow reserve. 25
  • MacCarthy P, Berger A, Manoharan G, Bartunek J, Barbato E, Wijns W, Heyndrickx GR, Pijls NH, De Bruyne B. J Am Coll Cardiol. 2005 Jan 18;45(2):216-20. Role of beta2 adrenergic receptors in human atherosclerotic coronary arteries. Barbato E, Piscione F, Bartunek J, Galasso G, Cirillo P, De Luca G, Iaccarino G, De Bruyne B, Chiariello M, Wijns W. Circulation. 2005 Jan 25;111(3):288-94. Epub 2005 Jan 10. Direct stenting of native de novo coronary artery lesions with the sirolimus-eluting stent: a post hoc subanalysis of the pooled E- and C-SIRIUS trials. Schlüter M, Schofer J, Gershlick AH, Schampaert E, Wijns W, Breithardt G; E- and C- SIRIUS Investigators. J Am Coll Cardiol. 2005 Jan 4;45(1):10-3. Association of plaque characterization by intravascular ultrasound virtual histology and arterial remodeling. Fujii K, Carlier SG, Mintz GS, Wijns W, Colombo A, Böse D, Erbel R, de Ribamar Costa J Jr, Kimura M, Sano K, Costa RA, Lui J, Stone GW, Moses JW, Leon MB. Am J Cardiol. 2005 Dec 1;96(11):1476-83. Epub 2005 Oct 12. Clinical efficacy of polymer-based paclitaxel-eluting stents in the treatment of complex, long coronary artery lesions from a multicenter, randomized trial: support for the use of drug-eluting stents in contemporary clinical practice. Dawkins KD, Grube E, Guagliumi G, Banning AP, Zmudka K, Colombo A, Thuesen L, Hauptman K, Marco J, Wijns W, Popma JJ, Koglin J, Russell ME; TAXUS VI Investigators. Circulation. 2005 Nov 22;112(21):3306-13. Epub 2005 Nov 14. Intracoronary beta-irradiation prevents excessive in-stent neointimal proliferation in de novo lesions of patients with high plasma ACE levels. The BetAce randomized trial. Ribichini F, Ferrero V, Piessens M, Heyndrickx GR, de Bruyne B, Verbeke L, Matullo G, Büchi M, Piazza A, Guarrera S, Lüscher TF, Wijns W. Cardiovasc Revasc Med. 2005 Jan-Mar;6(1):7-13. [Current concepts of the physiopathology of coronary beta-adrenergic receptors, and their clinical applications] Barbato E, Wijns W, De Bruyne B, Mascia G, Piscione F. Recenti Prog Med. 2005 Sep;96(9):411-5. Review. Italian. Hyperdynamic myocardial response to beta-adrenergic stimulation in patients with chest pain and normal coronary arteries. Madaric J, Bartunek J, Verhamme K, Penicka M, Van Schuerbeeck E, Nellens P, Heyndrickx GR, Wijns W, Vanderheyden M, De Bruyne B. J Am Coll Cardiol. 2005 Oct 4;46(7):1270-5. 26
  • [Percutaneous coronary interventions. Guidelines of the European Society of Cardiology- ESC.] Silber S, Albertsson P, Aviles FF, Camici PG, Colombo A, Hamm C, Jorgensen E, Marco J, Nordrehaug JE, Ruzyłło W, Urban P, Stone GW, Wijns W; European Society of Cardiology. Kardiol Pol. 2005 Sep;63(3):265-320; discussion 321-3. Review. Polish. No abstract available. Hybrid revascularization strategy: a pilot study on the association of robotically enhanced minimally invasive direct coronary artery bypass surgery and fractional-flow-reserve- guided percutaneous coronary intervention. Davidavicius G, Van Praet F, Mansour S, Casselman F, Bartunek J, Degrieck I, Wellens F, De Geest R, Vanermen H, Wijns W, De Bruyne B. Circulation. 2005 Aug 30;112(9 Suppl):I317-22. Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety. Bartunek J, Vanderheyden M, Vandekerckhove B, Mansour S, De Bruyne B, De Bondt P, Van Haute I, Lootens N, Heyndrickx G, Wijns W. Circulation. 2005 Aug 30;112(9 Suppl):I178-83. The Frontier stent registry: safety and feasibility of a novel dedicated stent for the treatment of bifurcation coronary artery lesions. Lefèvre T, Ormiston J, Guagliumi G, Schultheiss HP, Quilliet L, Reimers B, Brunel P, Wijns W, Buettner HJ, Hartmann F, Veldhof S, Miquel K, Su X, van der Giessen WJ. J Am Coll Cardiol. 2005 Aug 16;46(4):592-8. [Guidelines for percutaneous coronary interventions] Silber S, Albertsson P, Avilés FF, Camici PG, Colombo A, Hamm C, Jørgensen E, Marco J, Nordrehaug JE, Ruzyllo W, Urban P, Stone GW, Wijns W; Task Force per le Procedure Coronariche Percutanee della Società Europea di Cardiologia. Ital Heart J Suppl. 2005 Jul;6(7):427-74. Review. Italian. No abstract available. One-year outcomes of coronary artery bypass graft surgery versus percutaneous coronary intervention with multiple stenting for multisystem disease: a meta-analysis of individual patient data from randomized clinical trials. Mercado N, Wijns W, Serruys PW, Sigwart U, Flather MD, Stables RH, O'Neill WW, Rodriguez A, Lemos PA, Hueb WA, Gersh BJ, Booth J, Boersma E. J Thorac Cardiovasc Surg. 2005 Aug;130(2):512-9. Long-term clinical outcome after fractional flow reserve-guided percutaneous coronary intervention in patients with multivessel disease. Berger A, Botman KJ, MacCarthy PA, Wijns W, Bartunek J, Heyndrickx GR, Pijls NH, De Bruyne B. J Am Coll Cardiol. 2005 Aug 2;46(3):438-42. 27
  • Cardiac imaging in coronary artery disease: differing modalities. Schuijf JD, Shaw LJ, Wijns W, Lamb HJ, Poldermans D, de Roos A, van der Wall EE, Bax JJ. Heart. 2005 Aug;91(8):1110-7. Review. No abstract available. [Guidelines for percutaneous coronary interventions] Silber S, Albertsson P, Avilés FF, Camici PG, Colombo A, Hamm C, Jørgensen E, Marco J, Nordrehaug JE, Ruzyllo W, Urban P, Stone GW, Wijns W; Grupo de Trabajo de la Sociedad Europea de Cardiologia de intervención coronaria percutánia. Rev Esp Cardiol. 2005 Jun;58(6):679-728. Spanish. No abstract available. The diagnosis of coronary artery disease: in search of a "one-stop shop"? Wijns W. J Nucl Med. 2005 Jun;46(6):904-5. No abstract available. Angiographic, intravascular ultrasound, and fractional flow reserve evaluation of direct stenting vs. conventional stenting using BeStent2 in a multicentre randomized trial. Wijns W, Verheye S, Manoharan G, Werner GS, Grube E, De Bruyne B, Koolen J, Hamm CW, Medina A, Bech JW, De Feyter PJ; CONVERTIBLE investigators. Eur Heart J. 2005 Sep;26(18):1852-9. Epub 2005 May 11. Association of chronic kidney disease with clinical outcomes after coronary revascularization: the Arterial Revascularization Therapies Study (ARTS). Ix JH, Mercado N, Shlipak MG, Lemos PA, Boersma E, Lindeboom W, O'Neill WW, Wijns W, Serruys PW. Am Heart J. 2005 Mar;149(3):512-9. Diabetes does not influence treatment decisions regarding revascularization in patients with stable coronary artery disease. Breeman A, Bertrand ME, Ottervanger JP, Hoeks S, Lenzen M, Sechtem U, Legrand V, de Boer MJ, Wijns W, Boersma E. Diabetes Care. 2006 Sep;29(9):2003-11. Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial. Fajadet J, Wijns W, Laarman GJ, Kuck KH, Ormiston J, Münzel T, Popma JJ, Fitzgerald PJ, Bonan R, Kuntz RE; ENDEAVOR II Investigators. Circulation. 2006 Aug 22;114(8):798-806. Epub 2006 Aug 14. Sirolimus-eluting stent in chronic total occlusion: the SICTO study. Lotan C, Almagor Y, Kuiper K, Suttorp MJ, Wijns W. J Interv Cardiol. 2006 Aug;19(4):307-12. FX MiniRAIL catheter usage for treatment of de novo complex coronary lesions: results from the "OFFAR". 28
  • Vitrella G, Sangiorgi G, Kornowski R, Mosseri M, Almagor Y, Ischinger T, Pavlidis G, Rodermann J, Bartorelli A, Wijns W, Grube E, Colombo A; OFFAR Investigators. J Interv Cardiol. 2006 Jun;19(3):250-7. Intracoronary delivery of hematopoietic bone marrow stem cells and luminal loss of the infarct-related artery in patients with recent myocardial infarction. Mansour S, Vanderheyden M, De Bruyne B, Vandekerckhove B, Delrue L, Van Haute I, Heyndrickx G, Carlier S, Rodriguez-Granillo G, Wijns W, Bartunek J. J Am Coll Cardiol. 2006 Apr 18;47(8):1727-30. Epub 2006 Mar 27. No abstract available. Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation. Ickx BE, van der Linden PJ, Melot C, Wijns W, de Pauw L, Vandestadt J, Hut F, Pradier O. Transfusion. 2006 Apr;46(4):595-605. The consensus of the task force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for repair of the heart. Bartunek J, Dimmeler S, Drexler H, Fernández-Avilés F, Galinanes M, Janssens S, Martin J, Mathur A, Menasche P, Priori S, Strauer B, Tendera M, Wijns W, Zeiher A; task force of the European Society of Cardiology. Eur Heart J. 2006 Jun;27(11):1338-40. Epub 2006 Mar 16. Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry. Urban P, Gershlick AH, Guagliumi G, Guyon P, Lotan C, Schofer J, Seth A, Sousa JE, Wijns W, Berge C, Deme M, Stoll HP; e-Cypher Investigators. Circulation. 2006 Mar 21;113(11):1434-41. Epub 2006 Mar 13. Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from the Euro Heart Survey on Coronary Revascularization. Lenzen M, Scholte op Reimer W, Norekvål TM, De Geest S, Fridlund B, Heikkilä J, Jaarsma T, Mårtensson J, Moons P, Smith K, Stewart S, Strömberg A, Thompson DR, Wijns W. Eur J Cardiovasc Nurs. 2006 Jun;5(2):115-21. Epub 2006 Mar 10. Timing of intracoronary bone-marrow-derived stem cell transplantation after ST- elevation myocardial infarction. Bartunek J, Wijns W, Heyndrickx GR, Vanderheyden M. Nat Clin Pract Cardiovasc Med. 2006 Mar;3 Suppl 1:S52-6. Assessment of renal flow and flow reserve in humans. Manoharan G, Pijls NH, Lameire N, Verhamme K, Heyndrickx GR, Barbato E, Wijns W, Madaric J, Tielbeele X, Bartunek J, De Bruyne B. 29
  • J Am Coll Cardiol. 2006 Feb 7;47(3):620-5. Epub 2006 Jan 18. Meta-analysis of comparative diagnostic performance of magnetic resonance imaging and multislice computed tomography for noninvasive coronary angiography. Schuijf JD, Bax JJ, Shaw LJ, de Roos A, Lamb HJ, van der Wall EE, Wijns W. Am Heart J. 2006 Feb;151(2):404-11. Review. Relationship between noninvasive coronary angiography with multi-slice computed tomography and myocardial perfusion imaging. Schuijf JD, Wijns W, Jukema JW, Atsma DE, de Roos A, Lamb HJ, Stokkel MP, Dibbets-Schneider P, Decramer I, De Bondt P, van der Wall EE, Vanhoenacker PK, Bax JJ. J Am Coll Cardiol. 2006 Dec 19;48(12):2508-14. Epub 2006 Nov 28. Increased mortality after implantation of first generation drug-eluting stents: seeing the smoke, where is the fire? Wijns WC, Krucoff MW. Eur Heart J. 2006 Dec;27(23):2737-9. Epub 2006 Nov 15. No abstract available. Patients enrolled in coronary intervention trials are not representative of patients in clinical practice: results from the Euro Heart Survey on Coronary Revascularization. Hordijk-Trion M, Lenzen M, Wijns W, de Jaegere P, Simoons ML, Scholte op Reimer WJ, Bertrand ME, Mercado N, Boersma E; EHS-CR Investigators. Eur Heart J. 2006 Mar;27(6):671-8. Epub 2006 Jan 19. A comparative regional analysis of coronary atherosclerosis and calcium score on multislice CT versus myocardial perfusion on SPECT. Schuijf JD, Wijns W, Jukema JW, Decramer I, Atsma DE, de Roos A, Stokkel MP, Dibbets-Schneider P, van der Wall EE, Bax JJ. J Nucl Med. 2006 Nov;47(11):1749-55. Treatment decisions in stable coronary artery disease: insights from the Euro Heart Survey on Coronary Revascularization. Breeman A, Hordijk-Trion M, Lenzen M, Hoeks S, Ottervanger JP, Bertrand ME, Sechtem U, Zaliunas R, Legrand V, de Boer MJ, Stahle E, Mercado N, Wijns W, Boersma E; Euro Heart Survey on Coronary Revascularization. J Thorac Cardiovasc Surg. 2006 Nov;132(5):1001-9. Diagnostic and prognostic value of non-invasive imaging in known or suspected coronary artery disease. Schuijf JD, Poldermans D, Shaw LJ, Jukema JW, Lamb HJ, de Roos A, Wijns W, van der Wall EE, Bax JJ. Eur J Nucl Med Mol Imaging. 2006 Jan;33(1):93-104. Review. Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium. 30
  • Bartunek J, Croissant JD, Wijns W, Gofflot S, de Lavareille A, Vanderheyden M, Kaluzhny Y, Mazouz N, Willemsen P, Penicka M, Mathieu M, Homsy C, De Bruyne B, McEntee K, Lee IW, Heyndrickx GR. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1095-104. Epub 2006 Oct 20. The additional value of patient-reported health status in predicting 1-year mortality after invasive coronary procedures: a report from the Euro Heart Survey on Coronary Revascularisation. Lenzen MJ, Scholte op Reimer WJ, Pedersen SS, Boersma E, Maier W, Widimsky P, Simoons ML, Mercado NF, Wijns W; Euro Heart Survey on Coronary Revascularization. Heart. 2007 Mar;93(3):339-44. Epub 2006 Sep 15. Detailed intravascular ultrasound analysis of Zotarolimus-eluting phosphorylcholine- coated cobalt-chromium alloy stent in de novo coronary lesions (results from the ENDEAVOR II trial). Sakurai R, Hongo Y, Yamasaki M, Honda Y, Bonneau HN, Yock PG, Cutlip D, Popma JJ, Zimetbaum P, Fajadet J, Kuntz RE, Wijns W, Fitzgerald PJ; ENDEAVOR II Trial Investigators. Am J Cardiol. 2007 Sep 1;100(5):818-23. Epub 2007 Jun 14. Diagnostic performance of multidetector CT angiography for assessment of coronary artery disease: meta-analysis. Vanhoenacker PK, Heijenbrok-Kal MH, Van Heste R, Decramer I, Van Hoe LR, Wijns W, Hunink MG. Radiology. 2007 Aug;244(2):419-28. Effect of mitral valve repair on exercise tolerance in asymptomatic patients with organic mitral regurgitation. Madaric J, Watripont P, Bartunek J, Casselman F, Vanderheyden M, Van Praet F, Wijns W, Feys A, Vanermen H, De Bruyne B. Am Heart J. 2007 Jul;154(1):180-5. Thr164Ile polymorphism of beta2-adrenergic receptor negatively modulates cardiac contractility: implications for prognosis in patients with idiopathic dilated cardiomyopathy. Barbato E, Penicka M, Delrue L, Van Durme F, De Bruyne B, Goethals M, Wijns W, Vanderheyden M, Bartunek J. Heart. 2007 Jul;93(7):856-61. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Task Force for Diagnosis and Treatment of Non-ST-Segment Elevation Acute Coronary Syndromes of European Society of Cardiology, Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernández-Avilés F, Fox KA, Hasdai D, Ohman EM, Wallentin L, Wijns W. 31
  • Eur Heart J. 2007 Jul;28(13):1598-660. Epub 2007 Jun 14. No abstract available. What does the clinical cardiologist need from noninvasive cardiac imaging: is it time to adjust practices to meet evolving demands? Wijns W, De Bruyne B, Vanhoenacker PK. J Nucl Cardiol. 2007 May-Jun;14(3):366-70. Review. Multi-detector CT of the coronary arteries. Potential use of CT angiography and coronary artery calcium scoring in screening. Vanhoenacker R, Wijns W, Sarno G. JBR-BTR. 2007 Mar-Apr;90(2):80-3. Review. No abstract available. Percutaneous coronary intervention of functionally nonsignificant stenosis: 5-year follow-up of the DEFER Study. Pijls NH, van Schaardenburgh P, Manoharan G, Boersma E, Bech JW, van't Veer M, Bär F, Hoorntje J, Koolen J, Wijns W, de Bruyne B. J Am Coll Cardiol. 2007 May 29;49(21):2105-11. Epub 2007 May 17. Differences in plaque composition and distribution in stable coronary artery disease versus acute coronary syndromes; non-invasive evaluation with multi-slice computed tomography. Schuijf JD, Beck T, Burgstahler C, Jukema JW, Dirksen MS, de Roos A, van der Wall EE, Schroeder S, Wijns W, Bax JJ. Acute Card Care. 2007;9(1):48-53. The Cobalt chromium STent with Antiproliferative for Restenosis II (COSTAR II) trial study design: advancing the active-control evaluation of second-generation drug-eluting stents. Wang TY, Hasselblad V, Peterson JL, Wijns W, Parhizgar A, Kereiakes DJ, Krucoff MW. Am Heart J. 2007 May;153(5):743-8. The European Association of Percutaneous Cardiovascular Interventions. Interview with Dr. William Wijns by Emma Baines. Wijns W. Circulation. 2007 Apr 3;115(13):f57-8. No abstract available Tissue factor-dependent procoagulant activity of isolated human hepatocytes: relevance to liver cell transplantation. Stéphenne X, Vosters O, Najimi M, Beuneu C, Dung KN, Wijns W, Goldman M, Sokal EM. Liver Transpl. 2007 Apr;13(4):599-606. Erratum in: Liver Transpl. 2007 Jul;13(7):1070. Role of imaging in cardiac stem cell therapy. Beeres SL, Bengel FM, Bartunek J, Atsma DE, Hill JM, Vanderheyden M, Penicka M, Schalij MJ, Wijns W, Bax JJ. 32
  • J Am Coll Cardiol. 2007 Mar 20;49(11):1137-48. Epub 2007 Mar 6. Review. Anatomic-functional imaging by single-photon emission computed tomography/computed tomography as the cornerstone of diagnosis and treatment for coronary patients: a glimpse into the (near) future? Wijns W. J Am Coll Cardiol. 2007 Mar 13;49(10):1068-70. Epub 2007 Feb 26. No abstract available. Stent thrombosis late after implantation of first-generation drug-eluting stents: a cause for concern. Camenzind E, Steg PG, Wijns W. Circulation. 2007 Mar 20;115(11):1440-55; discussion 1455. Epub 2007 Mar 7. Review. No abstract available. Intracoronary beta-irradiation for the treatment of de novo lesions: 5-year clinical follow- up of the BetAce randomized trial. Ferrero V, Ribichini F, Piessens M, Heyndrickx GR, Verbeke L, de Bruyne B, Feola M, Vassanelli C, Wijns W. Am Heart J. 2007 Mar;153(3):398-402. Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial. Fajadet J, Wijns W, Laarman GJ, Kuck KH, Ormiston J, Münzel T, Popma JJ, Fitzgerald PJ, Bonan R, Kuntz RE; ENDEAVOR II Investigators. Minerva Cardioangiol. 2007 Feb;55(1):1-18. English, Italian. Bone-marrow-derived cells for cardiac stem cell therapy: safe or still under scrutiny? Bartunek J, Vanderheyden M, Wijns W, Timmermans F, Vandekerkhove B, Villa A, Sánchez PL, Arnold R, San Román JA, Heyndrickx G, Fernandez-Aviles F. Nat Clin Pract Cardiovasc Med. 2007 Feb;4 Suppl 1:S100-5. Cold cardioplegia for acute infarction a viable adjunct to reperfusion therapy? Wijns W, Heyndrickx GR. J Am Coll Cardiol. 2007 Jan 16;49(2):261-2. Epub 2006 Dec 29. No abstract available. Myocardial positive pre-ejection velocity accurately detects presence of viable myocardium, predicts recovery of left ventricular function and bears a prognostic value after surgical revascularization. Penicka M, Tousek P, De Bruyne B, Wijns W, Lang O, Madaric J, Vanderheyden M, Tintera J, Malý M, Widimsky P, Bartunek J. Eur Heart J. 2007 Jun;28(11):1366-73. Epub 2007 Jan 5. GLU-27 variant of beta2-adrenergic receptor polymorphisms is an independent risk factor for coronary atherosclerotic disease. 33
  • Barbato E, Berger A, Delrue L, Van Durme F, Manoharan G, Boussy T, Heyndrickx GR, De Bruyne B, Ciampi Q, Vanderheyden M, Wijns W, Bartunek J. Atherosclerosis. 2007 Oct;194(2):e80-6. Epub 2006 Nov 13. Time-dependent effects on coronary remodeling and epicardial conductance after intracoronary injection of enriched hematopoietic bone marrow stem cells in patients with previous myocardial infarction. Vanderheyden M, Vercauteren S, Mansour S, Delrue L, Vandekerckhove B, Heyndrickx GR, Van Haute I, De Bruyne B, Timmermans F, Wijns W, Bartunek J. Cell Transplant. 2007;16(9):919-25. Detection of non-ST-elevation myocardial infarction and unstable angina in the acute setting: meta-analysis of diagnostic performance of multi-detector computed tomographic angiography. Vanhoenacker PK, Decramer I, Bladt O, Sarno G, Bevernage C, Wijns W. BMC Cardiovasc Disord. 2007 Dec 19;7:39. Review. Zotarolimus-eluting stents in patients with native coronary artery disease: clinical and angiographic outcomes in 1,317 patients. Gershlick A, Kandzari DE, Leon MB, Wijns W, Meredith IT, Fajadet J, Popma JJ, Fitzgerald PJ, Kuntz RE; ENDEAVOR Investigators. Am J Cardiol. 2007 Oct 22;100(8B):45M-55M. Review. Universal definition of myocardial infarction. Thygesen K, Alpert JS, White HD; Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarction, Jaffe AS, Apple FS, Galvani M, Katus HA, Newby LK, Ravkilde J, Chaitman B, Clemmensen PM, Dellborg M, Hod H, Porela P, Underwood R, Bax JJ, Beller GA, Bonow R, Van der Wall EE, Bassand JP, Wijns W, Ferguson TB, Steg PG, Uretsky BF, Williams DO, Armstrong PW, Antman EM, Fox KA, Hamm CW, Ohman EM, Simoons ML, Poole-Wilson PA, Gurfinkel EP, Lopez- Sendon JL, Pais P, Mendis S, Zhu JR, Wallentin LC, Fernández-Avilés F, Fox KM, Parkhomenko AN, Priori SG, Tendera M, Voipio-Pulkki LM, Vahanian A, Camm AJ, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Morais J, Brener S, Harrington R, Morrow D, Lim M, Martinez-Rios MA, Steinhubl S, Levine GN, Gibler WB, Goff D, Tubaro M, Dudek D, Al-Attar N. Circulation. 2007 Nov 27;116(22):2634-53. Epub 2007 Oct 19. No abstract available. TAXUS VI 2-year follow-up: randomized comparison of polymer-based paclitaxel- eluting with bare metal stents for treatment of long, complex lesions. Grube E, Dawkins KD, Guagliumi G, Banning AP, Zmudka K, Colombo A, Thuesen L, Hauptman K, Marco J, Wijns W, Popma JJ, Buellesfeld L, Koglin J, Russell ME. Eur Heart J. 2007 Nov;28(21):2578-82. Epub 2007 Oct 14. Thrombin generation in plasma of healthy adults and children: chromogenic versus fluorogenic thrombogram analysis. 34
  • Devreese K, Wijns W, Combes I, Van kerckhoven S, Hoylaerts MF. Thromb Haemost. 2007 Sep;98(3):600-13. Advancing the knowledge base on the efficacy-safety ratio with drug-eluting stents contributions from the European Society of Cardiology Congress, Vienna, Austria, September 1-5, 2007. Wijns W, Braunwald E; European Society of Cardiology. J Am Coll Cardiol. 2007 Dec 18;50(25):2431-3. No abstract available. Multicenter assessment of coronary allograft vasculopathy by intravascular ultrasound- derived analysis of plaque composition. Sarno G, Lerman A, Bae JH, Schukro C, Glogar D, Margolis PM, Goethals M, Verstreken S, Bartunek J, Koenig A, Wijns W, Vanderheyden M. Nat Clin Pract Cardiovasc Med. 2008 Dec 2. [Epub ahead of print] [Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes] Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernandez-Aviles F, Fox KA, Hasdai D, Ohman EM, Wallentin L, Wijns W; Grupo de Trabalho para o Diagnóstico e Tratamento de Síndromes Coronárias Agudas sem Elevação do Segmento ST da European Society of Cardiology. Rev Port Cardiol. 2008 Sep;27(9):1063-143. Portuguese. No abstract available. Meeting Report * ESC Forum on Drug Eluting Stents * European Heart House, Nice, 27-28 September 2007. Authors/writing members, Daemen J, Simoons ML, Wijns W, Bagust A, Bos G, Bowen JM, Braunwald E, Camenzind E, Chevalier B, Dimario C, Fajadet J, Gitt A, Guagliumi G, Hillege HL, James S, Jüni P, Kastrati A, Kloth S, Kristensen SD, Krucoff M, Legrand V, Pfisterer M, Rothman M, Serruys PW, Silber S, Steg PG, Tariah I, Wallentin L, Windecker SW; Participants in the Forum, Aimonetti A, Allocco D, Baczynska A, Bagust A, Berenger M, Bos G, Boam A, Bowen JM, Braunwald E, Calle JP, Camenzind E, Campo G, Carlier S, Chevalier B, Daemen J, de Schepper J, Di Bisceglie G, Dimario C, Dobbels H, Fajadet J, Farb A, Ghislain JC, Gitt A, Guagliumi G, Hellbardt S, Hillege HL, Ten Hoedt R, Isaia C, James S, de Jong P, Jüni P, Kastrati A, Klasen E, Kloth S, Kristensen SD, Krucoff M, Legrand V, Lekehal M, Lenarz L, Ni Mhullain F, Nagai H, Patteet A, Paunovic D, Pfisterer M, Potgieter A, Purdy I, Raveau-Landon C, Rothman M, Serruys PW, Silber S, Simoons ML, Steg PG, Tariah I, Ternstrom S, Van Wuytswinkel J, Waliszewski M, Wallentin L, Wijns W, Windecker SW. Eur Heart J. 2008 Nov 26. [Epub ahead of print] No abstract available. Usefulness of proteinuria as a prognostic marker of mortality and cardiovascular events among patients undergoing percutaneous coronary intervention (data from the Evaluation of Oral Xemilofiban in Controlling Thrombotic Events [EXCITE] trial). Mercado N, Brugts JJ, Ix JH, Shlipak MG, Dixon SR, Gersh BJ, Lemos PA, Guarneri M, Teirstein PS, Wijns W, Serruys PW, Boersma E, O'Neill WW. Am J Cardiol. 2008 Nov 1;102(9):1151-5. Epub 2008 Aug 9. 35
  • Impact of atherosclerotic plaque composition on coronary microembolization during percutaneous coronary interventions. Böse D, von Birgelen C, Zhou XY, Schmermund A, Philipp S, Sack S, Konorza T, Möhlenkamp S, Leineweber K, Kleinbongard P, Wijns W, Heusch G, Erbel R. Basic Res Cardiol. 2008 Nov;103(6):587-97. Epub 2008 Sep 11. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Serruys PW, García-García HM, Buszman P, Erne P, Verheye S, Aschermann M, Duckers H, Bleie O, Dudek D, Bøtker HE, von Birgelen C, D'Amico D, Hutchinson T, Zambanini A, Mastik F, van Es GA, van der Steen AF, Vince DG, Ganz P, Hamm CW, Wijns W, Zalewski A; Integrated Biomarker and Imaging Study-2 Investigators. Circulation. 2008 Sep 9;118(11):1172-82. Epub 2008 Sep 1. Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non- inferiority trial. Windecker S, Serruys PW, Wandel S, Buszman P, Trznadel S, Linke A, Lenk K, Ischinger T, Klauss V, Eberli F, Corti R, Wijns W, Morice MC, di Mario C, Davies S, van Geuns RJ, Eerdmans P, van Es GA, Meier B, Jüni P. Lancet. 2008 Sep 27;372(9644):1163-73. Epub 2008 Aug 31. Evaluation of plaque characteristics in acute coronary syndromes: non-invasive assessment with multi-slice computed tomography and invasive evaluation with intravascular ultrasound radiofrequency data analysis. Pundziute G, Schuijf JD, Jukema JW, Decramer I, Sarno G, Vanhoenacker PK, Boersma E, Reiber JH, Schalij MJ, Wijns W, Bax JJ. Eur Heart J. 2008 Oct;29(19):2373-81. Epub 2008 Aug 5. Multidetector computed tomography angiography for assessment of in-stent restenosis: meta-analysis of diagnostic performance. Vanhoenacker PK, Decramer I, Bladt O, Sarno G, Van Hul E, Wijns W, Dwamena BA. BMC Med Imaging. 2008 Jul 31;8:14. Clinical and angiographic outcomes in diabetic patients following single or multivessel stenting in the COSTAR II randomized trial. Kereiakes DJ, Petersen JL, Batchelor WB, Fitzgerald PJ, Mehran R, Lansky A, Tsujino I, Schofer J, Dubois C, Verheye S, Cristea E, Garg J, Wijns W, Krucoff MW. J Invasive Cardiol. 2008 Jul;20(7):335-41. Relation of low response to clopidogrel assessed with point-of-care assay to periprocedural myonecrosis in patients undergoing elective coronary stenting for stable angina pectoris. Cuisset T, Hamilos M, Sarma J, Sarno G, Wyffels E, Vanderheyden M, Barbato E, Bartunek J, De Bruyne B, Wijns W. 36
  • Am J Cardiol. 2008 Jun 15;101(12):1700-3. Epub 2008 Apr 18. Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion. Hamilos MI, Ostojic M, Beleslin B, Sagic D, Mangovski L, Stojkovic S, Nedeljkovic M, Orlic D, Milosavljevic B, Topic D, Karanovic N, Wijns W; NOBORI CORE Investigators. J Am Coll Cardiol. 2008 Jun 3;51(22):2123-9. Quantification of coronary plaque by 64-slice computed tomography: a comparison with quantitative intracoronary ultrasound. Otsuka M, Bruining N, Van Pelt NC, Mollet NR, Ligthart JM, Vourvouri E, Hamers R, De Jaegere P, Wijns W, Van Domburg RT, Stone GW, Veldhof S, Verheye S, Dudek D, Serruys PW, Krestin GP, De Feyter PJ. Invest Radiol. 2008 May;43(5):314-21. A novel bioresorbable polymer paclitaxel-eluting stent for the treatment of single and multivessel coronary disease: primary results of the COSTAR (Cobalt Chromium Stent With Antiproliferative for Restenosis) II study. Krucoff MW, Kereiakes DJ, Petersen JL, Mehran R, Hasselblad V, Lansky AJ, Fitzgerald PJ, Garg J, Turco MA, Simonton CA 3rd, Verheye S, Dubois CL, Gammon R, Batchelor WB, O'Shaughnessy CD, Hermiller JB Jr, Schofer J, Buchbinder M, Wijns W; COSTAR II Investigators Group. J Am Coll Cardiol. 2008 Apr 22;51(16):1543-52. [Universal definition of the myocardial infarction.] Thygesen K, Alpert JS, White HD. Kardiol Pol. 2008 Jan;66(1):47-62. Polish. No abstract available. Direct stenting for stable angina pectoris is associated with reduced periprocedural microcirculatory injury compared with stenting after pre-dilation. Cuisset T, Hamilos M, Melikian N, Wyffels E, Sarma J, Sarno G, Barbato E, Bartunek J, Wijns W, De Bruyne B. J Am Coll Cardiol. 2008 Mar 18;51(11):1060-5. Endomyocardial upregulation of beta1 adrenoreceptor gene expression and myocardial contractile reserve following cardiac resynchronization therapy. Vanderheyden M, Mullens W, Delrue L, Goethals M, Verstreken S, Wijns W, de Bruyne B, Bartunek J. J Card Fail. 2008 Mar;14(2):172-8. Clinical imaging for prevention: directed strategies for improved detection of presymptomatic patients with undetected atherosclerosis--Part I: Clinical imaging for prevention. 37
  • Shaw LJ, Berman DS, Blumenthal RS, Budoff MJ, Faber TL, Goraya T, Halliburton SS, Hecht H, Kiat H, Koenig W, Malik S, Merhige M, Nasir K, Min JK, O'Keefe J, Polk DM, Raggi P, Rosenblatt JA, Schwartz RG, Taylor AJ, Thomas GS, Wijns W. J Nucl Cardiol. 2008 Jan-Feb;15(1):e6-19. Review. No abstract available. Drug-eluting stents: a critique. Melikian N, Wijns W. Heart. 2008 Feb;94(2):145-52. Review. Myocardial gene expression in heart failure patients treated with cardiac resynchronization therapy responders versus nonresponders. Vanderheyden M, Mullens W, Delrue L, Goethals M, de Bruyne B, Wijns W, Geelen P, Verstreken S, Wellens F, Bartunek J. J Am Coll Cardiol. 2008 Jan 15;51(2):129-36. Effects of sublingual nitroglycerin on coronary lumen diameter and number of visualized septal branches on 64-MDCT angiography. Decramer I, Vanhoenacker PK, Sarno G, Van Hoe L, Bladt O, Wijns W, Parizel PM. AJR Am J Roentgenol. 2008 Jan;190(1):219-25. Long-term histological and immunohistochemical findings in human venous aorto- coronary bypass grafts. Ribichini F, Pugno F, Ferrero V, Wijns W, Vacca G, Vassanelli C, Virmani R. Clin Sci (Lond). 2008 Feb;114(3):211-20. 38