Ernest S . Siwik, MD
1980 - 1985 Michigan State University Microbiology
East Lansing, MI BS with Honors
1985 - 1989 Wayne State University Doctor of Medicine
1989 - 1992 Rhode Island Hospital
Brown University / Providence, RI Pediatrics
1993 - 1996 Rainbow Babies & Children’s Hospitals
Case Western Reserve University
Cleveland, OH Pediatric Cardiology
1999 (1/1-4/1) Duke University Medical Center
Duke University / Durham, NC Interventional Cardiology
2001 (2/1-4/1) Children’s Hospital Boston
Harvard University / Boston, MA Interventional Cardiology
Certiﬁcation / Licensure
Massachusetts Medical License # 158626 inactive
Rhode Island Medical License # 09955 inactive
State of Ohio Medical License # 35-06-3371 current
American Board of Pediatrics # 052171 1993
Pediatric Cardiology Sub-Specialty Boards # 001452 1998
National Board of Medical Examiners # 373898 1990
State of Michigan Medical License # 059720 1992-1996
Drug Enforcement Agency # BS 3363912 current
RI Controlled Substance # CMD 09955 inactive
MA Controlled Substance # MS0395916A 1999-2001
2001- present Assistant Professor of Pediatrics, Case Western Reserve University
1999 - 2001 Assistant Professor of Pediatrics, Brown University
1999 (1/99-4/99) Visiting Assistant Professor of Pediatrics, Duke University
1996 - 1998 Assistant Professor of Pediatrics, Case Western Reserve University
1994 ACC Heart House Scholarship, Interventional Catheterization Session
1995 Genentech/ACC/AHA Cardiovascular Meetings Grant Recipient
2001 – present University Hospitals of Cleveland-Cleveland, OH (active staff)
2002 – present St. Elizabeth’s Hospital – Youngstown, OH (courtesy staff)
1999 - present Rhode Island Hospital/Hasbro Children’s-Providence RI (active staff)
1999 - 2001 Women’s & Infants Hospital-Providence, RI (active staff, resigned)
1999 - 2001 Kent County Hospital-Warwick, RI (consulting staff, resigned)
1999 - 2001 St. Vincent’s Hospital-Worcester, MA, (courtesy staff)
1996 - 1999 University Hospitals of Cleveland-Cleveland, OH (active staff, resigned)
1998 - 1999 Southwest General Health Center-Cleveland, OH (consultant staff)
1997 – 2001 Tods Children’s Hospital-Youngstown, OH (reactivated, 11/01 )
1997 - 1999 Aultman Hospital-Canton-OH (courtesy staff, resigned)
1993 - 1999 St. Luke’s Medical Center-Cleveland, OH (courtesy staff, resigned)
1994 - 1997 Meridia Euclid Hospital, Euclid, OH (active staff, resigned)
1992 - 1993 Cottage Hospital-Grosse Pointe Farms, MI (active staff, resigned)
Clinical/Research Positions Held
2001-present Director, Pediatric Catheterization Lab, University Hospitals/CWRU
2001-present Pediatric Cardiology Fellowship Director, University Hospitals/CWRU
2000-2001 Clinical consultant-McKesson HBOC
1999-2001 Pediatric Cardiac Catheterization Program Director, Hasbro Children’s
1997-1998 Consulting cardiologist for RB&C regional Williams syndrome clinic.
1994-1997 Level II NICU pediatrician - Meridia Euclid Hospital, Euclid, OH.
1992-1993 Staff pediatrician - Cottage Hospital, Grosse Pointe Farms, MI.
1991-1992 Level III NICU transport physician, Women & Infant’s Hospital, RI.
1990-1991 Level II NICU physican, Kent County Hospital, Warwick, RI.
1989 Research externship, AHRI, Addis Ababa, Ethiopia (2 months)
1986 Community substance abuse externship, Detroit, MI (3 months)
1983-1984 Psychiatric externship, CB Wilson Center, Fairbault, MN (6 months)
Society for Cardiac Angiography and Interventions 2001 - present
American Heart Association
Section on Cardiovascular Disease in the Young 1996 - present
American Academy of Pediatrics 1989 - 2000
American College of Cardiology, Associate Fellow 1993 - present
American Medical Association 1988 - 1993
Scientiﬁc / Professional Meetings Attended
Pediatric Interventional Cardiology Symposium 2003
European Pediatric Interventional Symposium 2000
AHA Symposium on Congenital Heart Disease (9/26-10/1) 1999
American College of Cardiology 1995,1996, 2001, 2002
American Heart Association 1994,1996
Weinstein CV Development Conference 1997
AHA CV Development Conference 1994
ODICH Regional CV Meeting 1996,1998,1999
ACC Heart House 1994,1995, 2000
1997-1998 Rainbow Board of Trustees Research Grant Amount: $ 29,000
Region-speciﬁc gene expression in a transfected heart model.
2003 Medical Education Committee, Department of Pediatrics
2000 Physician Incentive Compensation Committeee, RI Hospital
1997-1998 Rainbow Babies and Children’s Hospital Pediatric Liaison Committee
Postgraduate / Invited Lectures
2002 Grand Rounds / Catheter-Based Therapy / University Hospitals/RBC (10/10)
1999 Pediatric Grand Rounds / Hasbro Children’s Hospital (7/16)
1999 Grand Rounds / Pawtucket Memorial Hospital (10/27)
1999 Pediatric/Neonatology CPC/Women & Infant’s Hospital (7/99, 8/99)
1998 Visiting professor, National University, Lao PDR (10/3-10/17)
1998 Pediatric Grand Rounds, Khon Kaen University, Thailand. (10/98)
1997 Cardiology in the Newborn/Update in Neonatology/CME Program, (4/29)
1997 Williams Syndrome Heart Disease, Regional Williams Syndrome Assoc. (10/18)
1996 GAX & Heart Development -CWRU Pediatric Clinical Biennial Conference(10/17)
Other / Informal Teaching
2002 Management Conference / Neonatal Shock (7/02)
2001 Children’s Miracle Network TV Interview
1999 - 2001 Question-writer, American Board of Pediatrics-Pediatric Cardiology Exam
1997-1998 Resident Pediatric Board Review - Syncope/Arrhythmias (5/97, 6/98)
1997-1998 Pediatric Physical Diagnosis Preceptor
1994-1998 Cardiovascular Pathology Lab Preceptor, CWRU School of Medicine
1998 Faculty Advisor, CWRU Ice Hockey Club
1998 SVT Management, Critical Care Transport Service (7/98)
1998 SIDS and Long QT, Morning Exchange TV Program (6/98)
1997 Management Conferences / Endocarditis / Cardiac Rhabdomyomas
1991 Pediatric Advanced Life Support Instructor, Providence, RI
1996-present Cardiology fellow, medical student, resident teaching, 150 hours/year.
1996-1998 Blue team in-patient cardiology lectures, 10 hours/year.
Facher J, Regier B, Siwik ES, Robin NH. Cardiomyopathy in Cofﬁn-Lowry Syndrome. Am J of Med Genetics (In
Siwik ES, Perry SB, Lock JE. Endovascular Stent Implantation in Patients with Stenotic Aorto-Arteriopathies: Early
and Medium-term Results. Catheter and Cardiovasc Intervention. 2003 Jul 59(3):380-386.
Siwik ES, Spector ML, Patel CR, Zahka KG. Costs and cost-effectiveness of routine transesophageal
echocardiography in congenital heart surgery. Am Heart J, 138:771-776, 1999
Lane J, Siwik ES, Preminger TJ, Stork E, Spector ML. Prospective diagnosis of alveolar-capillary dysplasia in
patients with congenital heart disease. Am J Card, 84(5):618-620,1999
Watanabe M, Choudry A, Berlan M, Singal A, Siwik ES, Mohr S, Fisher SA. Developmental re-modeling and
shortening of the myocardial outﬂow tract involves myocyte programmed cell death. Development, 125(19) 3809-
Siwik ES, Wiesner G, Limwongse C, Zahka G. Cardiac disease in Costello syndrome.
Pediatrics, 101(4):706-709, 1998.
Siwik ES, Van Hare G. Severe cyanosis in a newborn after placement of a transvenous pacing wire. Pediatric
Cardiology, 19:168-107, 1998.
Fisher S, Siwik ES, Branellec D, Walsh K, Watanabe M. Forced expression of the homeobox protein Gax inhibits
myocyte proliferation and perturbs heart morphogenesis. Development 124, 4405-4413, 1997.
Siwik ES, Preminger TJ, Patel CR. Association of systemic to pulmonary collateral arteries with tetralogy of Fallot
and absent pulmonary valve syndrome. American Journal of Cardiology, 77:547-549, 1996
Lefford MJ, Hunegnaw M, Siwik ES. The value of IgM antibodies to PGL-1 in the diagnosis of leprosy.
International Journal of Leprosy, Vol. 59, No. 3, 1991
Neonatal Cardiac ECMO; A Single Institution Experience. Cabrera A, Mason K, Stork E, Lowrie L, Cornell D, Siwik
E. (2003 International Conference on Heart Failure in Young Adults, Houston TX)
Initial Experience with the Palmaz-Genesis�Pre-Mounted stents in Infants Weighing Less Than 10 KG. Siwik ES.
Catheter and Cardiovasc Intervention. 2003 September 60(1):136.
Etiologies and Outcomes of Cardiac ECMO Support in Neonates with Non-surgically Amenable Cardiac Disease.
Mason KE, Stork E, Lowrie L, Cornell D, Siwik ES. (2003 19th CNMC ECMO Meeting, Denver CO)
Endovascular Stent Implantation in Patients with Stenotic Aorto-Arteriopathies: Early and Medium-term Results.
Siwik ES, Lock JE, Perry SB. (2002 AHA, Atlanta GA)
Alveolar-capillary dysplasia in patients with congenital heart disease. Lane JR, Siwik ES, Preminger TJ, Stork E,
Spector ML. 26th ODICH Conference, 1999, Toledo)
Myocardial enodthelin-1 expression following cardiac injury in children. Siwik ES, Fisher SA, Preminger TJ,
Simonson MS. (25th ODICH Conference, 1998, Cleveland)
Developmental shortening of the myocardial outﬂow tract involves myocyte programmed cell death. Watanabe M,
Choudry A, Berlan M, Siwik E, Fisher S. (Weinstein CV Development Conference, 1998, Nashville)
Role of the homeodomain protein GAX in heart development. Fisher SA, Siwik ES, Branellec D, Walsh K, and
Watanabe M. (Weinstein Cardiovascular Development Conference, 1997, Cincinnati)
Molecular and cellular mechanisms in the morphogenesis of the outﬂow tract. Watanabe M, Choudry A, Singal A,
Siwik ES, Fisher SA. (Weinstein CV Development Conference, 1997, Cincinnati)
Impact of pediatric intraoperative transesophageal echocardiography on subsequent utilization of
echocardiography in congenital heart surgery. Siwik ES, Patel CR and Zahka KG. (24th ODICH Conference, 1996,
Adenoviral-mediated overexpression of the homeobox protein Gax alters heart morphogenesis. Fisher SA, Siwik
ES, Scopicki HA, Branellec D,Walsh K, Watanabe M. (69th Scientiﬁc Sessions, AHA, 1996, New Orleans)
Zahka KG, Siwik ES. Tetralogy of Fallot in Allen, Gutgesell, Clark and Driscoll (eds) Moss and Adams’ Heart
Disease in Infants, Children and Adolescents-6 William & Wilkins (2001)
Siwik ES, Everman D, Morrison S. Images in Cardiology: Crossed Pulmonary Arteries, Ventricular Septal Defect,
and Chormosome 22q11 Deletion. Heart 2002 Jul;88(1): 88
Siwik ES, Fischer SA, Simonson M. Myocardial endothelin-1 expression following cardiac insult in children.
(manuscript in preparation)