1. Elections to the
European Association of Percutaneous
Cardiovascular Interventions (EAPCI)
Application for the following position in the
EAPCI Board: (Treasurer)
Name: DUBOIS-RANDE Jean-Luc
Current Position: Professor of cardiolology, Head of the department of cardiology at
Henri Mondor Hospital
1 EAPCI Board elections 2009 - Applications
2. GENERAL CV (300 words max)
- FELLOWSHIP: 1981-1985
- CARDIOLOGIST degree: 1985
- ASSISTANT IN CARDIOLOGY IN THE CARDIOLOGY DEPARTMENT OF HENRI
MONDOR HOSPITAL, 1985-1989
- ASSOCIATE PROFESSOR IN THE CARDIOLOGY DEPARTMENT OF HENRI
MONDOR HOSPITAL, 1990-1994
- PHD IN 1990 (PhD): NEUROTRANSMISSION IN HEART FAILURE
- PROFESSOR OF CARDIOLOGY since 1994
- HEAD OF THE DEPARTMENT since 2000
I have been working as interventionist for more than 20 years and I participated in the
development of different tools in this field as laser with Pr Geshwind, left ventricular
assistance during high risk PCI and I am involved in the different main studies
concerning devices or drugs in this field. I participated with M Kern to the development
of coronary physiology in the setting of PCI by assessing stenosis with Doppler and
Besides clinical research, I participate to basic research in the field of endothelial
function, cardio protection and more recently cell therapy.
I am involved in the teaching of interventional cardiology. I launched the training
university program in interventional cardiology in France (Diplôme Interuniversitaire)
and I am still fully engaged in the teaching committee. More recently I participated to
the writing of the European teaching program (curriculum) with Pr Carlo Di Mario
published in Euro Intervention.
Reviewer in different journals: Interventional journal of Cardiology, European Heart
Journal, JACC, Circulation, European Journal of Heart Failure.
Besides interventional cardiology, I am involved in different heart failure groups
(national and European). Main field of expertise: ventricular assistance
Publications: more than 200 in Pubmed (Dubois-Rande JL and Rande JL)
Treasurer of 2 French associations and 1 foundation, previous treasurer of ESAC
(European group for aldosterone)
2 EAPCI Board elections 2009 - Applications
3. Previous experience in EAPCI, ESC or your National Bodies?
Writing of the curriculum in interventional cardiology
Speaker for the European Society of Cardiology, at EuroPCR, and for the European
Association of Echocardiography
Chairman in different European congresses and in different national congresses
Animal training program (labelled EBAC): for PFO closure, Coronary circulation
assessment (animal lab in Henri Mondor)
3 EAPCI Board elections 2009 - Applications
4. Publications (please list 10 max)
Loisance D, Dubois-Rande JL, Deleuze P, Okude J, Rosenval O, Geschwind H. Prophylactic intraventricular pumping in
high-risk coronary angioplasty. Lancet. 1990;335:438-40.
Merlet P, Delforge J, Syrota A, Angevin E, Maziere B, Crouzel C, Valette H, Loisance D, Castaigne A, Rande JL. Positron
emission tomography with 11C CGP-12177 to assess beta-adrenergic receptor concentration in idiopathic dilated
cardiomyopathy. Circulation. 1993;87:1169-78.
Larrazet FS, Dubois-Rande JL, Dupouy PJ, Hirosaka A, Kvasnicka J, Geschwind HJ. Angioscopy after laser and balloon
coronary angioplasty. J Am Coll Cardiol. 1994;23:1321-6.
Perchet H, Dupouy P, Duval-Moulin AM, Hittinger L, Pelle G, Brun P, Castaigne A, Geschwind H, Dubois-Rande JL.
Improvement of subendocardial myocardial perfusion after percutaneous transluminal coronary angioplasty. A myocardial
contrast echocardiography study with correlation between myocardial contrast reserve and Doppler coronary reserve.
Aptecar E, Dupouy P, Benvenuti C, Mazzucotelli JP, Teiger E, Geschwind H, Castaigne A, Loisance D, Dubois-Rande JL.
Sympathetic stimulation overrides flow-mediated endothelium-dependent epicardial coronary vasodilation in transplant
patients. Circulation. 1996;94:2542-50.
Kern MJ, Puri S, Bach RG, Donohue TJ, Dupouy P, Caracciolo EA, Craig WR, Aguirre F, Aptecar E, Wolford TL, Mechem
CJ, Dubois-Rande JL. Abnormal coronary flow velocity reserve after coronary artery stenting in patients: role of relative
coronary reserve to assess potential mechanisms. Circulation 1999; 100: 2491-8
Garot P, Pascal O, Simon M, Monin JL, Teiger E, Garot J, Gueret P, Dubois-Rande JL. Impact of microvascular integrity
and local viability on left ventricular remodelling after reperfused acute myocardial infarction. Heart 2003; 89: 393-7
Feldman LJ, Coste P, Furber A, Dupouy P, Slama MS, Monassier JP, Tron C, Lafont A, Faraggi M, Le Guludec D, Dubois-
Rande JL, Steg PG. Incomplete resolution of ST-segment elevation is a marker of transient microcirculatory dysfunction
after stenting for acute myocardial infarction. Circulation 2003 Jun 3 2003; 107: 2684-9.
Aptecar E, Lecorvoisier P, Teiger E, Garot P, Dupouy P, Sediame S, Vermes E, Loisance D, Hittinger L, Dubois-Rande JL.
Coronary vasomotor response to the selective B1-kinin-receptor agonist Des-Arg9-bradykinin in humans. J Heart Lung
Obame FN, Plin-Mercier C, Assaly R, Zini R, Dubois-Randé JL, Berdeaux A, Morin D. Cardioprotective effect of morphine
and a blocker of glycogen synthase kinase 3 beta, SB216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-
2,5-dione], via inhibition of the mitochondrial permeability transition pore. J Pharmacol Exp Ther. 2008 Jul;326(1):252-8.
Why should you be elected? (25 lines words max)?
I have an active experience as treasurer (national and International) so I can give time and
share this expertise for the EAPCI.
I would be honoured to participate to the different teaching programs since I am involved in
France and more recently in Europe. I think that a lot of work is necessary to homogenize
practice in the different EU countries.
While serving in a University, I can share my expertise with the different research programs of
4 EAPCI Board elections 2009 - Applications