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  • Biosketch Training Brenda Mickley Business Development Associate Lead, Federal Projects DCRI March 30, 2009
  • Objective
    • Review the reasons the NIH requires a biosketch
    • Review each section of a biosketch
    • Review why it’s important to understand the grants focus when creating a biosketch (i.e.-one biosketch does not fit all)
    • Review differences when we are submitting the grant electronically
  • Why is a Biosketch Important
    • It conveys to the NIH grant reviewer the experience that the investigator has in his professional career
      • Education
      • Positions held
      • Peer-reviewed publications
      • Funded research projects over last three years
    • Biosketch is a mini CV
  •  
  • Why is the Biosketch so Important
    • Recent Reviewers Comments when the biosketch isn’t personalized for the opportunity:
    • “ Why did this investigator not apply for new investigator on this grant”
      • Investigator did not list a current R01 in section C
    • “ This investigator does not have experience in this area”
      • Investigator did not include publications in research area
    • “ This investigator has not published in the last 2 years”
      • Investigator did not update biosketch
    Grants have become more competitive and reviewers are looking closely at the biosketch
  • The Basics
    • NIH Form:  http://grants.nih.gov/grants/funding/phs398/phs398.html
    • One-half inch margins (top, bottom, left, and right) for all pages, including continuation pages. 
    • eRA Commons ID 
    • NIH requires the use of one of four approved fonts and a font size of 11 points or larger . 
    • The approved font options include Palatino, Georgia, Arial, and Helvetica . 
    • The Biographical Sketch may not exceed four pages. 
  • Starting the Biosketch Christopher O’connor OCONN002  Professor of Medicine University of Maryland, College Park, MD B.S. 1979 Chemistry University of Maryland, Baltimore, MD M.D. 1983 Medicine Duke University, Durham, NC Intern 1984 Medicine Duke University, Durham, NC Resident 1988 Medicine Duke University, Durham, NC Fellow 1989 Cardiology
  • Three Additional Sections
    • A: Positions and Honors
    • B: Selected Peer-reviewed Publications
    • C: Research Support
  • A. Positions and Honors
    • List in chronological order previous positions, concluding the investigators present position.
    • List any honors.
    • Include present membership on any Federal Government public advisory committee.
  • Chronological Order Definition
    • : of, relating to, or arranged in or according to the order of time
    • Just be consistent!!
    • 1977 Predoctoral Fellow to Jackson Laboratory, National Institutes of Health
    • 1979 - 1981 Biologist, National Institutes of Health
    • 1983 - 1984 Intern in Medicine, Duke University Medical Center
    • 1984 - 1985 Junior Assistant Resident, Duke University Medical Center
    • 1985 - 1986 Senior Assistant Resident, Duke University Medical Center
    • 1986 - 1987 Assistant Medical Resident, Duke University Medical Center
    • 1987 - 1988 Chief Medical Resident, Durham Veterans Administration Hospital
    • 1988 - 1989 Fellow, Duke University Medical Center
    • 1989 - 1990 Associate in Medicine, Duke University Medical Center
    • 1990 - 1991 Co-Director, Coronary Care Unit, Duke University Medical Center
    • 1990 - 1996. Assistant Professor of Medicine, Duke University Medical Center
    • 1996 - Pres. Associate Professor of Medicine
    • 1991 - 1996 Co-Director, DUCCS Organization, Duke University Medical Center
    • 1996 - 1997 Executive Director, DUCCS Organization, Duke University Medical Center
    • 1997-Present Associate Director, Duke Clinical Research Institute
    • 1999-Present Director, Duke University Cooperative Cardiovascular Studies Organization, Duke University
    • 2000-Present Director, Heart Failure Program, Duke University Medical Center
    • 2001-Present Chief, Division of Clinical Pharmacology, Duke University Medical Center
    • 2003-Present Professor of Medicine, Duke University Medical Center
    • 2003-Present Associate Professor in Psychiatry and Behavioral Sciences
    Professional Experience:  2007-Present Director, Heart Center
  • Honors (selected):
    • American College of Cardiology/Bristol Fellow Achievement Award
    • American College of Physicians Clinical Vignette Award, Marion Labs, 3/4/88
    • Alpha Omega Alpha Medical Honor Society, University of Maryland, 1983
    • Epidemiology Award, University of Maryland School of Medicine, 1983
    • Upjohn Achievement Award (Excellence in Preventive Medicine) Univ. of Maryland School of Med. 1983
    • Phi Beta Kappa National Honor Society, University of Maryland, 1979
    • Goodard Medal (Outstanding Male Graduate UMCP), Univ. of Maryland, College Park, 1979
    • General Honors Program University of Maryland, College Park, 1979Magna Cum Laude, University of Maryland, College Park, 1979
    • Cum Laude, University of Maryland School of Medicine 1983
    • Miller Warner Newcomb Scholarship for Cancer Research
    • Any new Honors 
  • Honors (selected): What does this tell us?
    • Honors
    • 1986-88 Varsity letterman, ACC University, football
    • 1986-88 Academic All-Atlantic Coast Conference football team
    • 1990 Alpha Epsilon Delta (pre-medical honor society), ACC University
    • 1991 Phi Beta Kappa
    • 1991 Magna cum laude, ACC University
    • 1992 Senior Scholarship recipient, Duke University School of Medicine
    • 1995 Alpha Omega Alpha
    • 1998 Drug Company award for excellence in basic scientific research
  • B: Selected peer-reviewed publications
    • Selected peer-reviewed publications or manuscripts in press ( in chronological order ).
    • Do not include manuscripts submitted or in preparation.
    • For publicly available citations, URLs or PMC submission identification numbers should accompany the full reference.
    • Copies of publicly available publications are not accepted as appendix material.
  • PebMed Central ID (PMCID)-NOT PMID
    • The National Institutes of Health (NIH) Public Access Policy became effective April 7, 2008.
    • Under federal law, NIH now requires that the author’s final version of any peer-reviewed journal article resulting from NIH-funded activities must be submitted to the PubMed Central (PMC) repository
    • The publication will be made available to the public within 12 months after the journal article is published.
    • This new policy has several compliance issues that Duke authors need to address.
    • Update (March 12, 2009): President Obama has signed into law the 2009 Consolidated Appropriations Act, which includes a provision making the NIH Public Access Policy permanent.
  • Pub Med Central (PMC) Helpful Links
    • Pubmed Central: http:// www.pubmedcentral.nih.gov /
    • NIH Public Access Policy FAQ: http:// publicaccess.nih.gov/FAQ.htm
    • Journals that systematically submit articles to PubMed Central: http:// publicaccess.nih.gov/submit_process_journals.htm
    • Tutorial on the NIHMS System: http://www.nihms.nih.gov/web-help/index.html
    • Information and services provided by Duke Medical Center Library: http:// www.mclibrary.duke.edu/nihpolicy
  • Example
    • Podgoreanu MV, White WD, Morris RW, Matthew JP, Stafford-Smith M, Welsby IJ, Grocott HP, Milano CA, Newman MF, Schwinn DA. “Inflammatory Gene Polymorphisms and Risk of Postoperative Myocardial Infarction after Cardiac Surgery”. Circulation 2006;114 (suppl I): I-275-I-281. PMC1945056
  • B: Selected peer-reviewed publications
    • What does the Publications tell you about the investigators career?
    • Hlatky MA, Cotugno H, O'Connor C , Mark DB, Pryor DB, Califf RM. Adoption of thrombolytic therapy in the management of acute myocardial infarction. Am J Cardiol 1988;61(8):510-4.
    • O'Connor CM , Califf RM, Massey EW, Mark DB, Kereiakes DJ, Candela RJ, Abbottsmith C, George B, Stack RS, Aronson L, et al. Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. J Am Coll Cardiol 1990;16(3):533-40.
    • Whellan DJ, Shaw LK, Bart BA, Kraus WE, Califf RM, O'Connor CM. Cardiac rehabilitation and survival in patients with left ventricular systolic dysfunction. Am Heart J 2001; 142 (1) : 160-6.
    Third Author: part of research team First Author, his research project, counts towards tenure Senior Author, mentored first author, counts towards tenure
  • QUESTION??
    • What do you do when you have over 166 publications and only have 2 pages worth of space?
  • B: Selected peer-reviewed publications
    • Grant focus
    • Authorship position
    • NIH funded manuscript
    • Journal “impact rating”
  • B: Selected peer-reviewed publications
    • Grant focus: Heart Failure
      • 74 Publications
    • Authorship
      • First Author: 19
      • Senior Author: 35
    • NIH Funded Publication
      • 43
    • Journal “Impact Factor”
  • Copyright restrictions may apply. Garfield, E. JAMA 2006;295:90-93. Selected Biomedical Journals Ranked by Impact Factor
  • B: Selected peer-reviewed publications
    • Journal “Impact Factor”
      • JAMA-5 publications
          • O’Connor is first author on two
      • Lancet-1 publication
          • O’Connor is senior author
      • Ann Intern Med-1 publication
      • Arch Intern Med-8 publications
          • O’Connor is senior author on five
  • Research Support
    • List both selected ongoing and completed research projects
    • Past three years (Federal or non-Federally-supported). 
    • Begin with the projects that are most relevant to the research proposed in the application.
    • Briefly indicate the overall goals of the projects and responsibilities of the key person identified on the Biographical Sketch.
    • Do not include number of person months or direct costs.
  • Research Support
    • 5U01-HL063747-05 O’Connor (PI) 9/30/02 – 6/30/2009
    • NHLBI
    • ACTION: A CHF Trial Investigating Outcomes of Exercise Training
    • The DCRI is the Coordinating center for this multi-center randomized trial whose goal is to assess if exercise training improves clinical outcomes for heart failure.
    • Role: PI
  • Research Support
    • Do not confuse "Research Support" with "Other Support."
    • "Research Support" highlights the investigators accomplishments
    • This information will be used by the reviewers in the assessment of each individual's qualifications for a specific role in the proposed project, as well as to evaluate the overall qualifications of the research team.
    • "Other Support" information is required for all applications that are selected to receive grant awards and includes detailed financial information
  • Why a biosketch isn’t a “one size fits all”
    • Type of grant: research grant vs. a mentoring grant
    • Grant Focus
    • Role on Grant
  • NIH Biosketch for Electronic Submission
    • Just delete the header and footer!!
  • QUESTIONS???