American Heart Association Funding Opportunities (Powerpoint)

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  • The AHA receives applications for a wide variety of research areas, including: Behavioral research Epidemiological research Mental health studies Nutrition Obesity Quality of Life The AHA is especially interested in receiving more Stroke applications. This is a research area in which we’d like to see more growth.

Transcript

  • 1. American Heart Association Funding Opportunities Annie Oliveto Director of Research
  • 2. Who We Are
    • AHA is the largest funding source for CVD/Stroke research other than the NIH.
    • Founded in 1924—close to $3 billion spent on research, $1 billion in the last 10 years alone.
    • Last year AHA spent $152 million in research, $11.8 was through the Western States Affiliate.
    • AHA spends more on research (by percentage) than any other non-profit health organization.
  • 3. Research Funding Donor Dollar 25% 75% National Center Western States Research Allocation 21% 15%
  • 4. Breakthroughs Funded by AHA
    • The first artificial heart valve.
    • Techniques and standards for CPR
    • Implantable pacemakers to
    • regulate irregular
    • heartbeats.
    • Heart-lung machine
    • C holesterol inhibitors
    • On top of research innovations, the AHA has created programs to implement science: Get With the Guidelines,
    • medical journals, conferences, professional and public education
  • 5. Breakthroughs Still Needed in CVD Research
    • Obesity and cholesterol reduction
    • Modify behaviors leading to CVD and Stroke
    • Diabetes and heart disease
    • Congenital heart defects
    • CVD/ Stroke in African Americans and other ethnic groups
    • Strategies to understand and treat
    • heart failure
    • Gene studies
    • Abnormal heart rhythms
  • 6. Breakthroughs Still Needed in Stroke Research
    • Stroke Treatments
    • Brain Imaging Techniques
    • Stroke Risk Factors, Education & Awareness
    • Stroke and Dementia
    • Recovery from Stroke
    • Gene and Protein Research
  • 7. AHA’s Research Focus
    • Training and career development of
    • beginning scientists
    • Support of cutting
    • edge basic and
    • clinical science
  • 8. What Kinds of Research Do We Support? The AHA supports research that is broadly related to the cardiovascular area and stroke.
  • 9. Life Cycle of a Research Application Idea Begins Assigned to Reviewers Peer Review Rank Ordered List Developed Reports Published Application submitted Research completed Findings translated Critique developed $ Funded
  • 10. Western Review Consortium Peer Review Committees Cell Transport and Metabolism, Cellular CV Physiology & Pharmacology, Molecular Signaling Lipoproteins & Lipid Metabolism, Thrombosis, Vascular Wall Biology CV Development, Immunology & Microbiology, Basic Cell & Molecular Biology Behavioral Science, Epidemiology & Prevention, CV Regulation, Cardiac (Patho) Physiology, Radiology & Imaging Brain, Cardiorenal, Lung, Respiration, Surgery
  • 11. Undergraduate Student Research Program Encourages research careers related to the cardiovascular or cerebrovascular areas. $4K – 10 weeks Medical Student Research Award Provides an opportunity to explore a research career related to the cardiovascular area or stroke. $600/wk – 8-12 weeks Western States Affiliate Promotes Careers in Research STUDENT RESEARCH PROGRAMS
  • 12. Western States Affiliate Promotes Careers in Research FELLOWSHIP AWARDS Predoctoral Fellowships - Undergraduate Students I nitiates careers in cardiovascular and stroke research and supports doctoral dissertation projects. $18,500/yr – 2-3 years Postdoctoral Fellowship - PhD and MD trainees Initiates careers in cardiovascular and stroke research, and furthers research training while obtaining significant research results. $30K-46K/yr – 2-3 years
  • 13. GRANTS Beginning-Grant-In-Aid – Beginning Scientists Promotes independent status and supports high quality research projects. $70K/yr – 2-4 years Grant-In-Aid -- Independent Investigators Supports the most innovative and meritorious research. $70K/yr – 2-4 years *AHA National offers Scientist Development Grants, Fellow to Faculty, Established Investigator Awards and Clinical Research Awards
  • 14. Did you know that the AHA Funds:
    • Behavior Studies
    • Biomedical Ethics
    • Cardiac Rehabilitation
    • Clinical Trials
    • Compliance
    • Coping Strategies / Stress Mgt
    • Depression
    • Epidemiology
    • Exercise / Physical Activity
    • Familial Aggregation / Genetic Epidemiology
    • Health Care Utilization/Cost Effectiveness
    • Health Promotion/Prevention
    • Human Nutrition (Behavioral and Preventive Aspects)
    • Obesity
    • Nutrition
    • Outcomes Research
    • Preventive Cardiology
    • Quality of Life
    • Social Support Systems
    • Stroke
    • Weight Control
  • 15. HUMAN EMBRYONIC or FETAL STEM CELLS AND HUMAN FETAL TISSUE or HUMAN CLONING
    • Ineligible for funding:
    • Cloning of humans as asexual reproduction or cloning of humans intended as sources of tissue or organs to harvest are not acceptable.
    • Ineligible for funding:
    • Derivation or use of human stem cells from in vitro fertilization (IVF) treatment embryos or fetal sources.
    • Use of human fetal tissue.
    Areas Ineligible for AHA Funding
  • 16. FATAL FLAWS Common Mistakes Made When Applying for Funding
  • 17. FATAL FLAWS by Investigators
    • No demonstration of expertise or publications in approaches, low productivity
    • No collaborators recruited or no letters from collaborators
    • Unnecessary experimental detail
    • Not enough detail on approaches, especially untested ones
    • Not enough preliminary data to establish feasibility, nor any correlative or descriptive data
    • Feasibility of each aim not shown
    • Little or no expertise with approach
    • Lack of appropriate controls
    • Not directly testing hypothesis
  • 18. FATAL FLAWS Significance
    • Not significant nor exciting nor new research
    • Lack of compelling rationale
    • Incremental and low impact research
    • Innovation is not always necessary, but the results should have compelling significance
    • Little demonstration of institutional support
    • Little or no start up package or necessary equipment
  • 19. FATAL FLAWS Resubmissions
    • Insulting the reviewers
    • Only responding to specific reviewer concerns and not other aspects that may be newly criticized
    • Just changing the name or submitting a previous project as new
    • Do not send the same or similar application for review without indicating that it is a resubmission
    • AHA allows 2 resubmssions + Original allowed
  • 20. DEADLINES Take them seriously!
    • ~5% are administratively withdrawn each year (NIH and AHA)
    • Technical problems? Call before the 5:00 pm deadline.
    • Applications received after 5:00pm are administratively withdrawn.
    • Acknowledgement of receipt should be received within 24 hours after electronic submission.
    • READ the acknowledgement for possible errors in electronic upload of your application.
  • 21. Late Applications
    • Contact AHA staff before deadline if experiencing problems with the electronic website.
    • Late paper copies may be accepted for genuine reasons and if electronic submission was on time.
  • 22. Administrative Withdrawal
    • Late electronic or paper copies
    • Modifications after deadline
    • Format issues:
      • type size
      • characters per inch (CPI)
      • lines per page
      • exceeding page limits
  • 23. Streamlined Review “Triage”
    • Removes noncompetitive applications from the review process
    • Applicants receive critiques, but not scores
    • Applies to fellowships and grants
    • 40% of consortia applications can be triaged
  • 24. PREDOCTORAL FELLOWSHIP APPLICANTS
    • Describe undergraduate/ graduate research activities:
      • research participation programs
      • student-originated study programs
      • research gained through summer or part-time employment
      • research within course work and/or outside of the classroom
      • Summarize, stating problems studied and conclusions reached
  • 25. Technical Support
    • Request technical assistance from AHA
    • Seek advice on administrative issues from your grants management specialist
  • 26. Questions and Answers Annie Oliveto 650-259-6715 [email_address]