Your SlideShare is downloading. ×
Dna
Upcoming SlideShare
Loading in...5
×

Thanks for flagging this SlideShare!

Oops! An error has occurred.

×
Saving this for later? Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime – even offline.
Text the download link to your phone
Standard text messaging rates apply

Dna

714
views

Published on

Published in: Technology, Business

0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
714
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
4
Comments
0
Likes
0
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
No notes for slide

Transcript

  • 1. DNA
  • 2. DNA is a nucleic acid• A nucleic acid is a polymer of nucleotides• A nucleotide is made from a phosphate, sugar and base.• www.chemsoc.org
  • 3. Phosphate• From phosphoric acid• http://bio.winona.edu/berg/ChemStructures/Phospha2.gif
  • 4. Sugar• Deoxyribose in DNA (Ribose in RNA)• http://www.mun.ca/biology/scarr/Deoxyribose_vs_Ribose.gif
  • 5. Nucleotide• Condensation between the phosphate and sugar (at C5) and between the sugar (at C1) and base• http://distancelearning.ksi.edu/demo/bio378/DNA_files/image002.gif
  • 6. Dinucleotide• Two nucelotides join by condensation• http://pages.towson.edu/jdrawn/Chapter_1_Intro_to_Bioinfo_files/image005.jpg• Condensation gives phosphodiester bridge
  • 7. Polynucleotide• Up to 5 x 106 nucleotides long• http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/oligo.gif• 5’ end• 3’ end
  • 8. DNA double helix• The bases of the DNA nucleic acid form H bonds to bases of a second molecule of DNA
  • 9. • A bonds to T with two hydrogen bonds• G bonds to C with three hydrogen bonds.• http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/B/BasePairing.gif
  • 10. • A is the ~same amount as T• G is the ~same amount as C• Amount of purines equals the amount of pyrimidines• A always bonds to T• G always bonds to C• Known as Chargaff’s Rule
  • 11. Table from Biological Science – Green, Stout, Taylor
  • 12. • The two nucleic acids wind into a double helix, with H bonds between polar groups of sugars keeping the shape of the helix.• (diagram from Bioligical Sciences, green, Stout & Taylor)
  • 13. • The two strands are ANTIPARALLEL• i.e. they are parallel, but run in opposite directions.
  • 14. http://www.accessexcellence.org/RC/VL/GG/images/dna2.gif
  • 15. Arrangement of DNA in chromosomeshttp://www.biology.emory.edu/research/Lucchesi/multimedia/images/insert2.jpg
  • 16. Histones in nucleosome• DNA is wrapped around a group of 8 histone proteins and held together by another histone molecule• http://employees.csbsju.edu/hjakubowski/classes/ch331/dna/nucleosome.gif
  • 17. • Nucleosomes:• Help in supercoiling of DNA• Help to regulate transcription
  • 18. DNA from a single skin cell, ifstraightened out, would be about six feet long but invisible. Half a gram of DNA, uncoiled, would stretch to the sun. Again, you couldnt see it.