Your SlideShare is downloading. ×
0
Papulosquamous dermatoses
<ul><li>1-psoriasis </li></ul><ul><li>Psoriasis is a chronic proliferative epidermal disease </li></ul><ul><li>Pathogenesi...
Histopathology 1-parakeratosis <ul><li>2-absent stratum granulosum </li></ul><ul><li>3-acanthosis </li></ul><ul><li>4-munr...
Clinical picture <ul><li>Red papules & plaques covered with silver scales </li></ul><ul><li>Sites: extensors, elbow, knee,...
 
 
Clinical forms: <ul><li>1-punctate </li></ul><ul><li>2-guttate </li></ul><ul><li>3-discoid </li></ul><ul><li>4-annular </l...
Types: <ul><li>1-flexural </li></ul><ul><li>2-psoriasis of palm & sole </li></ul><ul><li>3-erythrodermic </li></ul><ul><li...
 
Koebner phenomenon <ul><li>Appearance of isomorphic pathologic lesions in traumatized uninvolved skin in psoriatic patient...
Treatment: <ul><li>1-topical </li></ul><ul><li>Crude tar </li></ul><ul><li>Salicylic acid </li></ul><ul><li>Corticosteroid...
2-lichen planus <ul><li>Clinical picture </li></ul><ul><li>Itchy flat topped polygonal violaceous papules with white lines...
Varieties of LP: <ul><li>1-LP linearis </li></ul><ul><li>2-LP annularis </li></ul><ul><li>3-LP atrophicus </li></ul><ul><l...
 
 
Histopathology <ul><li>1-hyperkeratosis </li></ul><ul><li>2-focal hypergranulosis </li></ul><ul><li>3-acanthosis </li></ul...
Treatment <ul><li>1-topical </li></ul><ul><li>Corticosteroid </li></ul><ul><li>2-systemic </li></ul><ul><li>Antihistamines...
3-pityriasis rosea <ul><li>Clinical picture </li></ul><ul><li>Begins with bright red oval patch (herald patch) </li></ul><...
Etiology <ul><li>1-infective agent </li></ul><ul><li>2-drug induced </li></ul><ul><li>3-autoimmune </li></ul><ul><li>Treat...
 
4- pityriasis rubra pilaris(PRP) <ul><li>Chronic skin disease characterized by diffuse & follicular hyperkeratosis </li></...
Types: <ul><li>1-classical adult </li></ul><ul><li>2-atypical adult </li></ul><ul><li>3-classical juvenile </li></ul><ul><...
 
Upcoming SlideShare
Loading in...5
×

Papulosquamous dermatoses

3,707

Published on

0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
3,707
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
89
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

Transcript of "Papulosquamous dermatoses"

  1. 1. Papulosquamous dermatoses
  2. 2. <ul><li>1-psoriasis </li></ul><ul><li>Psoriasis is a chronic proliferative epidermal disease </li></ul><ul><li>Pathogenesis </li></ul><ul><li>1-biochemical abnormalities </li></ul><ul><li>2-immunologic abnormalities </li></ul><ul><li>3-abnormal leucocytic function </li></ul>
  3. 3. Histopathology 1-parakeratosis <ul><li>2-absent stratum granulosum </li></ul><ul><li>3-acanthosis </li></ul><ul><li>4-munro micro abscess </li></ul><ul><li>5-elongation and edema of dermal papillae </li></ul><ul><li>6-mononuclear infiltrate </li></ul>
  4. 4. Clinical picture <ul><li>Red papules & plaques covered with silver scales </li></ul><ul><li>Sites: extensors, elbow, knee, scalp & nails </li></ul><ul><li>Auspitz sign </li></ul><ul><li>Scraping of lesions with glass slide results in removal of scales until thin membrane appears its scraping shows pin point bleeding . </li></ul>
  5. 7. Clinical forms: <ul><li>1-punctate </li></ul><ul><li>2-guttate </li></ul><ul><li>3-discoid </li></ul><ul><li>4-annular </li></ul><ul><li>5-gyrate </li></ul>
  6. 8. Types: <ul><li>1-flexural </li></ul><ul><li>2-psoriasis of palm & sole </li></ul><ul><li>3-erythrodermic </li></ul><ul><li>4-psoriasis of nail </li></ul><ul><li>5-psoriasis of scalp </li></ul><ul><li>6-pustular psoriasis </li></ul><ul><li>7-arthropathic psoriasis </li></ul>
  7. 10. Koebner phenomenon <ul><li>Appearance of isomorphic pathologic lesions in traumatized uninvolved skin in psoriatic patient. </li></ul><ul><li>Other diseases with koebner: LP, PRP, vitiligo </li></ul>
  8. 11. Treatment: <ul><li>1-topical </li></ul><ul><li>Crude tar </li></ul><ul><li>Salicylic acid </li></ul><ul><li>Corticosteroid </li></ul><ul><li>Calcipotriol </li></ul><ul><li>2-systemic </li></ul><ul><li>Acitretin </li></ul><ul><li>Immunosuppressive as methotrexate </li></ul><ul><li>3-phototherapy </li></ul><ul><li>PUVA </li></ul>
  9. 12. 2-lichen planus <ul><li>Clinical picture </li></ul><ul><li>Itchy flat topped polygonal violaceous papules with white lines (Wickham's striae) </li></ul><ul><li>Sites: flexors, glans penis </li></ul>
  10. 13. Varieties of LP: <ul><li>1-LP linearis </li></ul><ul><li>2-LP annularis </li></ul><ul><li>3-LP atrophicus </li></ul><ul><li>4-LP hypertrophicus </li></ul><ul><li>5-LP of palm & sole </li></ul><ul><li>6-lichen plano-pilaris </li></ul><ul><li>7- LP actincus </li></ul><ul><li>8- LP of mucous membrane </li></ul><ul><li>A-white streaks c-ulcerative </li></ul><ul><li>B-white plaques </li></ul>
  11. 16. Histopathology <ul><li>1-hyperkeratosis </li></ul><ul><li>2-focal hypergranulosis </li></ul><ul><li>3-acanthosis </li></ul><ul><li>4-liquefactive degeneration of basal layer </li></ul><ul><li>5-band like infiltrate </li></ul>
  12. 17. Treatment <ul><li>1-topical </li></ul><ul><li>Corticosteroid </li></ul><ul><li>2-systemic </li></ul><ul><li>Antihistamines </li></ul><ul><li>Corticosteroid in 1-acute generalized cases </li></ul><ul><li>2-oral ulcerative </li></ul><ul><li>3-severe itching </li></ul>
  13. 18. 3-pityriasis rosea <ul><li>Clinical picture </li></ul><ul><li>Begins with bright red oval patch (herald patch) </li></ul><ul><li>After 5-15 days, discrete medallions oval patches appears ,usually in trunk, neck,& proximal extremities, covered with fine scales </li></ul><ul><li>Types: </li></ul><ul><li>1-classical </li></ul><ul><li>2-abortive </li></ul><ul><li>3-inverted </li></ul>
  14. 19. Etiology <ul><li>1-infective agent </li></ul><ul><li>2-drug induced </li></ul><ul><li>3-autoimmune </li></ul><ul><li>Treatment </li></ul><ul><li>1-antihistamines </li></ul><ul><li>2-calamine for pruritus </li></ul><ul><li>3-reassurance </li></ul>
  15. 21. 4- pityriasis rubra pilaris(PRP) <ul><li>Chronic skin disease characterized by diffuse & follicular hyperkeratosis </li></ul><ul><li>Clinical picture </li></ul><ul><li>1- scaly scalp </li></ul><ul><li>2-psoriatic-like patches </li></ul><ul><li>3-hyperkeratoses of palm & sole </li></ul><ul><li>4-follicular hyperkeratosis </li></ul><ul><li>5-nails are brittle, rough & dystrophic </li></ul><ul><li>6- erythroderma with islands of normal skin </li></ul>
  16. 22. Types: <ul><li>1-classical adult </li></ul><ul><li>2-atypical adult </li></ul><ul><li>3-classical juvenile </li></ul><ul><li>4-circumscribed juvenile </li></ul><ul><li>5-atypical juvenile </li></ul><ul><li>Treatment </li></ul><ul><li>Topical steroid </li></ul><ul><li>Salicylic acid </li></ul><ul><li>Methotrexate </li></ul>
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×