NIOH report on endosulfan - key issues

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The presentation states that the committees which reviewed the NIOH study on Endosulfan did not find any confirmation which states that endosulfan is harmful. In absence of confirmation the residues of Endosulfan reported by NIOH cannot be accepted. Besides the NIOH study has also reported Endosulfan residues far below the minimum limit of detection of GC-ECD. The call for a ban on Endosulfan is not justified on a scientific basis and endosulfan can be used on fruits and vegetables without fear of residues. They also stated that there is no health effect on exposure to Endosulfan…http://whybanendosulfan.org

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NIOH report on endosulfan - key issues

  1. 1. KEY ISSUES – NIOH REPORT ON  ENDOSULFAN
  2. 2. ENDOSULFAN REGISTRATION Endosulfan is a sulfurous acid ester of chlorinated  cyclic diol and was registered in India by Registration  Committee under the Insecticide Act after considering  all the data on chemistry, residues, bioefficacy and  toxicology data including acute oral and dermal  toxicity, skin irritation, carcinogenicity, mutageneicity,  tetragenecity in the country.
  3. 3. EXPERT COMMITTEESSeveral committees have been constituted by Ministry of Agriculture and Ministry of Health and Family Welfare of the Govt. of India to review the use of Endosulfan: Dr S N Banerjee Committee (ex‐plant protection advisor, Govt. of  India) Dr R B Singh Committee (Director IARI) Kerala Agricultural University Committee (appointed by Vice  Chancellor, KAU) Mr. Achyutan Committee (Noted Environmentalist) Dr O P Dubey Committee (ex‐Additional Director General, Plant  Protection, ICAR) Dr C D Mayee Committee (Agricultural Commissioner) Dr Y K Gupta Committee (Professor & Head of Pharmacology,  AIIMS)The various committees considered scientific data on chemistry, bioefficiacy, carcinogenecity, mutagenecity, tetragenecity, epidimological studies and reports from FAO, WHO, information from Agricultural Universities and from ICAR institutes
  4. 4. EXPERT COMMITTEE FINDINGS The expert committees noted that there is no  link established in the use of Endosulfan and  the health problems reported in Padre  village in Kerala and recommended the  continued use of Endosulfan as per the  provisions of the Insecticides Act.
  5. 5. COMMENTS ON NIOH STUDY The committees have reported that several studies were  conducted in establishing the levels of endosulfan and its  metabolites in biological samples, soil and water. The committees had observed that for detecting  low levels of  residue use of highly sophisticated instruments and high class  expertise is required.  The studies were not done using such instruments  The committee indicated that confirmation of Endosulfan  Residues by GCMS/LCMS is required as per international norms. It  is likely that different molecules with structural similarity may  appear in the same peak due to similar retention time. 
  6. 6. INTERNATIONAL PRACTICES In the meeting of CODEX committee of Pesticide  Residues held at The Hague, Netherlands in May 2002  Good Laboratory Practices on Pesticide Residue  Analysis it was emphasised that when analysis are  performed for monitoring on enforcement purposes it  is especially important that confirmation data should  be generated before reporting data on residues of  pesticides.
  7. 7. FLAWS OF NIOH REPORT The committees which reviewed the NIOH study on  Endosulfan did not find any reports where such  confirmation was done. In absence of confirmation the  residues of Endosulfan reported by NIOH cannot be  accepted. Besides the NIOH study has also reported Endosulfan  residues far below the minimum limit of detection of  GC‐ECD.
  8. 8. RECENT IMPORTANT STUDIES Recent Monitoring Study by National Project on  Monitoring of Ministry of Agriculture above 15,000  samples of fruits and vegetables have been analysed for  Endosulfan residues and in almost all the samples  residues of Endosulfan were well below the Maximum  Residue Limits (MRL) Endosulfan can be used on fruits and vegetables  without fear of residues
  9. 9. CONCLUSION• There is no health effect on exposure to  Endosulfan. • The call for a ban on Endosulfan is not justified  on a scientific basis.
  10. 10. PRESENTED BY: Rakesh Sethi – 09 Ankita Kapadia – 14 Maithili Prabhakar ‐ 24
  11. 11. THANK YOU

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