Music from DNA strings Animesh Sharma

DNA strings? Word (sequence) Made out of 4 letters (nucleotides) Certain patterns more prevalent Hold information Coding Non Coding ...AGGGTTAGGGTTAGGGTTAGG...* ...AGGGTTAGGGTTAGGGTTAGG... ...AGGG TTAGGG TTAGGGTTAGG... * A Highly Conserved Repetitive DNA Sequence,(TTAGGG)n,Present at the Telomeres of Human Chromosomes Moyzis et al. PNAS | September 15, 1988 | vol. 85 | no. 18 | 6622-6626 Copyright © 1988 by the National Academy of Sciences ...UCCCAATCCCAAUCCCAAUCC...

Word (sequence)

Made out of 4 letters (nucleotides)

Certain patterns more prevalent

Hold information

Coding

Non Coding

Abstraction At nMers and repeat level ...AGGGTTAGGGTTAGGGTTAGG... AGG = 0 GTT = 1 ... 0 1 0 1 0 1 0 ... Frequency level ...AGGGTTAGGGTTAGGGTTAGG... G = 1 ...011100011100011100011... A = 1 ...100000100000100000100... T = 1 ...000011000011000011000... C = 1 ...000000000000000000000...

At nMers and repeat level

Frequency level

REF: Ab initio gene identification: prokaryote genome annotation with GeneScan and GLIMMER. Aggarwal G, Ramaswamy R. J Biosci. 2002 Feb;27(1 Suppl 1):7-14. G = 1 ...011100011100011100011... A = 1 ...100000100000100000100... T = 1 ...000011000011000011000... C = 1 ...000000000000000000000...

* MIDI-Perl , http://search.cpan.org/~sburke/MIDI-Perl-0.81/ OR http://interglacial.com/~sburke/midi-perl/ Sean M. Burke 30 Jan 2005. What about Music? Encode ^ MIDI::Perl * C – Channel O – Octave N – Note ^ The Musician's Guide to MIDI by Christian Braut

Thanks I hope I took less than 15 mts !

I hope I took less than 15 mts !