ToxinsBacterial Exotoxinsstaph                      can produce superantigenstrep                      ~lysins that lyse m...
VaccinesViruses• attenuated           polio, measles, mumps, rubella, yellow fever   (pathology makes me reallY feverish)•...
ZoonosesViruses• west nile• yellow fever• vaccinia• ebola• rabies• influenza A, avian flu• japanese encephalitis• lassa feve...
Propagated OutbreaksBacteriamnemonictuesday         - typhoidwednesday       - whooping coughthursday        - TBdays     ...
Upcoming SlideShare
Loading in...5
×

Popular Pathology MCQ Topics

3,096

Published on

A summary of very popular MCQ topics in 2nd year pathology of medical school in Cambridge.

0 Comments
2 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
3,096
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
68
Comments
0
Likes
2
Embeds 0
No embeds

No notes for slide

Popular Pathology MCQ Topics

  1. 1. ToxinsBacterial Exotoxinsstaph can produce superantigenstrep ~lysins that lyse membrane by pore formation, also superantigendiphtheria toxin inhibits EF-2 and thereby protein synthesisclostridium perfringens alpha toxin that degrades membrane phospholipids (PLC)clostridium tetani tetanus toxin inhibits vesicle release from inhibitory interneurons => spasmclostridium botulinum botox inhibits vesicle release at NMJ => paralysisclostridium difficile GLUCOSYLATES small ATPases, changes cytoskeleton, makes epi leakybacillus anthracis toxin is adenylate cyclaseshiga toxin glycosiDASE, modifies rRNA => stops protein synthesisE.coli labile toxin similar to cholera toxin, ribosylates Gs always ONE.coli stable toxin upregulates cGmpE.coli haemolysin lyses red cells by pore formationbordetella pertussis toxin ribosylates Gi always OFFcholera toxin ribosylates Gs always ONhelicobacter pylori VacA vacuolating toxin, CagA increases proliferation => link to canceryersinia pestis YopT changes cytoskeleton,YopP induces apoptosisOtherplasmodium falsiparum GPI (glycosylphosphotidyl inositol), activating TNFa and ICAMsfungi Ergotamine, aflatoxin...
  2. 2. VaccinesViruses• attenuated polio, measles, mumps, rubella, yellow fever (pathology makes me reallY feverish)• deletion mutant rabies• killed virus polio, influenza, rabies, f&m, hep A (pathology is rapidly found hell)• subunit hep BBacteria• live (aTTenuated) Typhoid, TB• inactivated whooping cough, cholera• ToxoiD tetanus, diphtheria• subunit pneumonia, meningitis
  3. 3. ZoonosesViruses• west nile• yellow fever• vaccinia• ebola• rabies• influenza A, avian flu• japanese encephalitis• lassa fever• SARS• HIV (?)Bacteria Zoonotic NOT Zoonotic EHEC 0157 MRSA• EHEC Salmonella Enteridis Salmonella TYPHUS• salmonella enteritidis and Typhinurium Shigella• yersinia pestis C. Difficile Cholera TB Dysentery Campylobacter Listeria Plague Anthrax Lyme Ricksettia
  4. 4. Propagated OutbreaksBacteriamnemonictuesday - typhoidwednesday - whooping coughthursday - TBdays - diphtheriagone - gonorrheadevising - dysenterycatchy - choleramnemonicsFood PoisoningCl. BotulismCl Perfingens (spores)Staph AureusSalmonella enteritidis NOT typhiE.Coli0157 (EHEC)ETEC (9/04Q30e)Listeria (yes)Campylobacteriacholera (9/04 Q 30A)HepA
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×