Parasites overview

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An overview on parasites

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Parasites overview

  1. 1. Eukaryotic Group Subgroup lifecycle detail size epidemiology infection pathology subtype falciparum vivax mosquito: malariae 1. microgamete 2. macrogamete 3. zygote * active * fever 4. ookinete * complex * headache 5. oocyst response and * spleno- 6. Bursting oocyst evasion megaly 7. sporozoites 250 million * evasion: * multiple Plasmodium indirect human: microscopic worldwide PfEMP organ failure 7. sporozoite ovale * CD8 in liver and cerebral (8. hypnozoite) * AB to sporo + malaria in 9. merozoite mero + proteins falsiparum due 10. trophozoite (inProtozoae * natural to sequestration ery) selection 11a. schizont-9. 11b. gametocyte to mosquito Leishmania Trypanosoma * mild * active * ocular invasion of * ingest (oo)cyst toxoplasmosis direct and 13% of world cells, but also Toxoplasma gondii * new cysts develop microscopic and fatal CNS indirect population phagocytosis * oocyst in faeces disorders if * vacuole immuno- protects compromised
  2. 2. Eukaryotic Group Subgroup lifecycle detail size epidemiology infection pathology subtype * ingest eggs * larvae in 1.5 billion * TH2 * GI symptoms bloodstream worldwide, * IgE * blockage/perf ascaris lumbricoides direct * via lung and 15-35cm! mainly africa * mastocytosis airway into GI tract and asia * eosinophilia * adult worms in small intestine * passive * larva into skin * AChE * worm in gut, most common Nematode necator americanus * superoxide * anaemia direct feeds on blood 1cm species in nippostrongylus brasiliensis dismutase * GI symptoms * eggs in faeces, humans * kills T-cells will form larva by apoptosis! fly: Metazoae * microfilariae * larvae * elephantiasis wucheria bancrofti Wb: 10cm * passive indirect human: * river onchocerca volvvulus OV: 40cm invasion * larvae blindness * microfilariae into lymphatic sys mansoni * immuno- * no japonicum pathology snail: multiplication * granuloma 1. miricadia(aq) in host around eggs 2. sporocysts * TH2 cerariae 200 million * fibrosis Trematodes schistosoma indirect 3. cercariae(aq) * IgE 200mm? infected * portal haematobium human: * worms hypertension in 4. schistosomulae immuno- m+j 5. miricadiae(aq) suppress host * haematuria in and alter IgE h. Cestode Hymenolepis diminuta

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