Overview of pathogens and parasites

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An overview of the pathogens and parasites taught in pathology of the 2nd year medical course in Cambridge.

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Overview of pathogens and parasites

  1. 1. Christiane’s Parasite Overview Categorised overview of Parasites • subcellular: Viruses • prokaryotes – unicellular: Bacteria • eukaryotes: 1. Fungi Unicellular: yeasts Multicellular: molds o Yeasts:  Candida albicans  Cryptococcus neoformans  Pneumocystis carinii o Filamentous fungi:  Aspergillus fumigatus  Mucor o Dimorphic fungi:  Histoplasma capsulatum 2. Protozoae – unicellular with complex life cycle Reproduce directly in host 2.1. Plasmodium  Malaria 2.2. Leishmania  Leishmaniasis 2.3. Trypanosomes  Sleeping sickness 2.4. Toxoplasma gondii  Toxoplasmosis (birth defects) 3. Metazoae – multicellular, also with complex life cycle No direct replication in definite host (where sexual maturity is reached) 3.1. Nematodes different worms  Giant roundworm • Ascaris lumbricoides  Ascariasis  Hookworm  intestinal hook- • Necator americanis worm infection • Nippostrongylus brasiliensis  Filarial worm  Filiariasis • Wuchereria bancrofti  Elephantiasis • Onchocerca volvvulus  River blindness 3.2. Trematodes “flukes”, flatworms  Schistosoma, mansoni, japonicum, haematobium  schistosomiasis 3.3. Cestodes tapeworms  Hymenolepis diminuta  hymenolepiasis • Direct life cycle = single host • Indirect life cycle = multiple hosts

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