Loading…

Flash Player 9 (or above) is needed to view presentations.
We have detected that you do not have it on your computer. To install it, go here.

Like this presentation? Why not share!

52684484 04-dra-nur-anisah-systema-genitalia-feminina

on

  • 881 views

 

Statistics

Views

Total Views
881
Slideshare-icon Views on SlideShare
881
Embed Views
0

Actions

Likes
0
Downloads
70
Comments
0

0 Embeds 0

No embeds

Accessibility

Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
Post Comment
Edit your comment

    52684484 04-dra-nur-anisah-systema-genitalia-feminina 52684484 04-dra-nur-anisah-systema-genitalia-feminina Presentation Transcript

    • NUR ANISAH BAGIAN HISTOLOGI & BIOLOGI SEL, FAKULTASKEDOKTERAN, UNIVERSITAS GADJAH MADA, YOGYAKARTA Blok Sistem Reproduksi, 9 Feb 2010 [04] SISTEM REPRODUKSI WANITA
    • Sistem reproduksi wanita memiliki enam fungsi utama:
      • Menghasilkan gamet betina, yaitu ovum,
      • melalui proses oogenesis
      • Menerima gamet jantan, yaitu spermatozoa
      • Menyediakan lingkungan yang sesuai untuk
      • pembuahan ovum oleh spermatozoa
      • Menyediakan lingkungan yang sesuai untuk
      • perkembangan janin
      • Merupakan alat untuk mengeluarkan janin
      • matang ke lingkungan luar
      • Nutrisi untuk bayi baru lahir
    • GAMBARAN UMUM SISTEM REPRODUKSI WANITA
      • █ KOMPONEN SISTEM
      • ■ Ovarium (indung telur)
      • ■ Tuba uterina (tuba Falopii/oviduct)
      • ■ Uterus (rahim)
      • ■ Vagina
      • ■ Apparatus genitalia externa
    • ORGANA GENITALIA FEMININA
      • ORGANA GENITALIA EXTERNA
      • ORGANA GENITALIA INTERNA
    • Organa genitalia feminina interna dan externa Ø lateral organa genitalia feminina
    • Figure . Internal organs of the female reproductive system.
    • 1. Ovarium
      • ● Organ ini merupakan gonade
      • ● Tersusun oleh:
      • - folikel-folikel -> perkembangan telur
      • (ovum)
      • - setelah folikel masak, ovum dilepaskan,
      • sedangkan folikel yg tertinggal
      • membentuk -> corpus luteum :
      • memproduksi hormon estrogen &
      • progesteron
    • Figure 23—2. Ovary of a woman of reproductive age showing its main components: germinal epithelium, tunica albuginea, cortical region, and medullary region.
    • Figure. Photomicrograph of part of an ovary showing the cortical and medullary regions. H&E stain. Low magnification. Ovary human, H&E
    • Folliculus ovarii
      • Folliculus primordialis
      • Pertumbuhan follikel:
      • a. Folliculi primarius:
      • i. Folliculus primarius unilaminarius
      • ii. Folliculus multilaminarius
      • b. Folliculus secundarius
      • Folliculus maturus = folliculus de Graaf
      • Folliculus atreticus
    • Fig. Types of ovarian follicles, from primordial to mature. The relative proportions of the follicles are not maintained in this drawing.
    • Perkembangan folikel
      • Folliculus ovarii
      • Epitel
      • Cortex
    • Figure 23—6. Cortical region of an ovary. Besides primordial follicles formed by an oocyte and flat follicular cells, a few follicles at the initial stage of growth (unilaminar primary follicles) are present. These are formed by an oocyte and one layer of cuboidal granulosa cells. Pararosaniline—toluidine blue (PT) stain. Low magnification.
    • Figure 23—7. Photomicrograph of a preantral ovarian follicle formed by an oocyte and several layers of granulosa cells. The oocyte is surrounded by the zona pellucida. Picrosirius-hematoxylin (PSH) stain. Medium magnification.
    • Folliculus secundarius Folliculus de Graaf
    • Figure 23—9. Photomicrograph of part of an antral follicle. Cavities (A) that appear in the granulosa layer will fuse and form one large cavity, the antrum. The oocyte is surrounded by the zona pellucida. Granulosa cells (G) surround the oocyte and cover the wall of the follicle. A theca can be seen around the follicle. H&E. Medium magnification.
    • Figure 23—10. Photomicrograph of an antral follicle showing the oocyte surrounded by the granulosa cells of the corona radiata and supported by the cells of the cumulus oophorus. The remaining granulosa cells form the wall of the follicle and surround the large antrum. A theca surrounds the whole follicle. PT stain. Medium magnification.
    • Figure 23—11. Photomicrograph of a small part of the wall of an antral follicle, showing the antrum, the layer of granulosa cells, and the thecas. The theca interna surrounds the follicle, and its cells appear lightly stained because their cytoplasm contains lipid droplets, a characteristic of steroid-producing cells. The theca interna is surrounded by the theca externa, which merges with the stroma of the ovary. A basement membrane separates the granulosa layer from the theca interna. PT stain. High magnification.
    • Figure 23—12. Photomicrograph of the atresia of a follicle characterized by: (1) the death of granulosa cells, many of which are seen loose in the antrum; (2) loss of the cells of the corona radiata; and (3) the oocyte floating free within the antrum. PT stain. Medium magnification.
    • Figure 23—13. Part of a corpus luteum. Granulosa lutein cells, which constitute the majority of the cells, derive from the granulosa layer. They are larger and stain more lightly than the theca lutein cells, which originate from the theca interna.
    • Figure 23—14. Photomicrograph of a small portion of a corpus luteum. Most cells present in the figure are granulosa lutein cells. PT stain. High magnification.
    • Figure 23—15. Pituitary hormones control most ovarian functions. Follicle-stimulating hormone (FSH) stimulates follicular growth and synthesis of estrogen by the granulosa cells. - Luteinizing hormone (LH) induces ovulation and transforms the granulosa layer and the theca interna into an actively secreting gland, the corpus luteum. - Estrogen and progesterone produced in the ovary act on the hypothalamus, stimulating or inhibiting the liberation of gonadotropin-releasing hormone (GnRH).
    • Figure 23—16. Corpus albicans, the scar of connective tissue that replaces a corpus luteum after its involution.
    • Corpus luteum
    • Corpus albicans
      • mrpk massa jar. fibrosa tidak aktif
      • Gamb. utama ovarium manusia, jumlahnya meningkat dng usia, sering tampak menempati hampir seluruh jar. stroma ovarium
    • 2. Tuba uterina (oviduct)
      • Terdapat sepasang, panjang ± 12 cm
      • Menjaring ovum yang telah lepas
      • Sebagai tempat utama fertilisasi
      • Membawa ovum ke uterus, baik yang sudah mengalami fertilisasi maupun yang belum mengalami fertilisasi, transportasi zygot ke uterus
    • Bagian-bagian tuba uterina
      • Pars interstitialis
      • Isthmus
      • Ampulla
      • Infundibulum, lanjutan lapisan mukosanya berbentuk seperti jari-jari -> fimbriae
    • Figure 23—17. Photomicrograph of part of the wall of an oviduct. The highly folded mucosa indicates that this region is close to the ovary. PT stain. Low magnification.
    • Figure 23—18. Photomicrograph of the epithelial lining of an oviduct. The epithelial lining is formed by ciliated and more darkly staining nonciliated secretory cells. Ciliated cells contribute to the movement of the oocyte or conceptus to the uterus. PT stain. High magnification.
    • Struktur dinding tuba uterina
      • 1. Tunika mukosa: Epithelium simplex columnare:
      • a. Kolumner bersilia
      • b. “Peg cells” -> berukuran rendah, diantara
      • sel-sel bersilia, mensekresi mukus:
      • - menolong transportasi ovum dan
      • menghalang-halangi masuknya bakteri
      • ke cavum peritonii
      • 2. Tunika muskularis: lamina circularis internus dan longitudinale externus -> kontraksi otot ini menggerakkan ovum menuju uterus
      • 3. Tunika serosa
    • Tuba uterina (tuba Fallopii)
    • Ampula & ismus tuba uterina
    • 3. Uterus
      • Dilapisi oleh mukosa (endometrium) yg mengalami perubahan-perubahan struktur berkala -> dikendalikan oleh hormon ovarium
      • Berperan sebagai tempat implantasi dan pemberian makanan ovum yg telah mengalami fertilisasi
    • Bagian-bagian uterus:
      • Badan = body atau corpus
      • Fundus
      • Cervix atau leher
    • Struktur dinding uterus:
      • Fundus dan corpus disusun oleh 3 lapisan:
      • - Myometrium: otot polos 4 lapis
      • - Endometrium: mukosa uterus t.d.:
      • selapis epitel kolumner, lamina propria,
      • gld. tubuler simplex.
      • Endometrium : - stratum fungsionale
      • - stratum basale
      • - Tunika serosa atau adventitia: Jar. ikat
    • Uterus
      • Fundus
      • Tumor otot /Leiomyoma
      • Body
      • Endocervix
      • Cervix
      • Ectocervix
    • Tipe leiomyoma kecil
    • Endoserviks
    • Serviks uteri
    • Carsinoma cervix
      • Sel epitel cervix
      • Sel epitel abnormal
      • Membana basalis
      • Stroma
    • Korpus uteri fase haid
      • Vagina
      • Mrpk organ serupa tabung ini membantu
      • mendorong sperma melalui cervix
      • Cairan di dalam lumen vagina menambah
      • motilitas sperma
      • Di bawah pengaruh estrogen, epitel vagina
      • menebal dan sel-selnya menimbun glikogen,
      • yg dilepaskan ke dalam lumen selama proses
      • pengelupasan.
    • Vagina
    • Vagina
    • 5. Apparatus genitalia externa
      • ● Terdiri atas : - Clitoris
      • - Labium mayus
      • - Labium minus
      • ● Mengandung sejumlah besar
      • ujung-ujung serabut saraf ->
      • berperan di dalam merangsang
      • gairah seksual
    •  
    • Siklus menstruasi
      • Uterus -> Lap. Mukosa: - endometrium
      • - miometrium
      • Perubahan siklis endometrium berlangsung melalui 2 fase:
      • * Fase proliferasi
      • * Fase sekresi
    •  
    •  
    • Endometrium proliferatif
    • Endometrium proliferatif
    • Endometrium
    • Endometrium
    • Endometrium: permulaan menstruasi
    • Permukaan endometrium
    • Endometrium: pasca menopause
    • Endometrium pasca menopause
    • Miometrium
    • Fertilisasi dan implantasi
    • Plasenta
    •  
    •  
    • Desidua
      • a. desidua -> hub. Perkembangan fetus&plasenta
      • b. desidua :
      • - parietalis(DP)
      • - capsularis (DC)
      • - basalis (DB)
      • c. sel desidua:
      • - poligonal
      • - nukleus tercat pucat
      • - granula sitoplasma
      • eosinofilik
    • Desidua
    • Plasenta tahap awal
    • Bagian tepi vilus
    • Plasenta muda
    • Plasenta tua
    • Plasenta tua
    • Membran janin
    • Funikulus umbilikalis
    • Funikulus umbilikalis (tali pusat)
    • GLANDULA MAMMAE
    • - Schematic drawing of the female breast showing inactive and active mammary glands. - Each lactiferous duct with its accompanying smaller ducts is a gland in itself and constitutes the lobes of the gland.
    • Figure 23—28. Changes in the mammary gland. A: In nonpregnant women, the gland is quiescent and undifferentiated, and its duct system is inactive. B: During pregnancy, alveoli proliferate at the ends of the ducts and prepare for the secretion of milk. C: During lactation, alveoli are fully differentiated, and milk secretion is abundant. Once lactation is completed, the gland reverts to the nonpregnant condition.
    • Glandula mammae
    • STRUKTUR MAMMAE
      • Terdiri dari : Jaringan alveolar (kelenjar susu) :
      • * lobus-lobus dipisahkan oleh j. ikat & j.
      • lemak
      • * setiap lobus bermuara ke ductus
      • lactiferus (saluran air susu)
      • * Saluran limfe sebagai plexus halus dalam
      • septum interlobularis jaringan kelenjar
      • -> membentuk saluran yang lebih besar
    • Photomicrograph of lactating mammary gland. Several alveoli are filled with milk, visible as granular material. The vacuoles in the lumen and in the alveolar cell cytoplasm represent the lipid portion of milk. PT stain. Medium magnificatio n.
    • Figure 23—30. Secreting cells from the mammary gland. From left to right, note the accumulation and extrusion of lipids and proteins. The proteins are released through exocytosis.
    • Glandula mammae
    • Kelenjar mamma non-aktif
    • Glandula mammae selama kehamilan
    • Glandula mammae dalam masa laktasi
    • Kelenjar mamma dalam masa laktasi
    • ORGANA GENITALIA FEMININA
      • ORGANA GENITALIA EXTERNA
      • ORGANA GENITALIA INTERNA
    • ORGANA GENITALIA EXTERNA
      • CLITORIS
      • VESTIBULUM
      • LABIUM MINUS
      • LABIUM MAYUS
      • KELENJAR DEWASA (SELAMA KEHAMILAN)
      • KELENJAR LAKTASI
      • INVOLUSI SENILIS
    • FUNGSI :
      • Sebagai jalan masuk sperma ke
      • dalam tubuh wanita
      • Sebagai pelindung organ kelamin
      • dalam dari organisme penyebab
      • infeksi
    •  
    • Klitoris
    • Labium minus
    • Labium mayus