The Marketing Services & Solutions ProviderPlanning your attack against coccidiosisAuthored by: Dr. Sekhar Basak, Innovist...
The Marketing Services & Solutions Providerproducts to use and which ones to rest, as long as you keep in mind that they o...
The Marketing Services & Solutions ProviderAmprolium is a good anticoccidial for the control of cecal coccidiosis, but is ...
The Marketing Services & Solutions Providerof the resistant Eimeria strain into a more sensitive population, and to enable...
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Planning your attack against coccidiosis

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Planning your attack against coccidiosis

  1. 1. The Marketing Services & Solutions ProviderPlanning your attack against coccidiosisAuthored by: Dr. Sekhar Basak, Innovista Consulting, New DelhiThe battle against coccidiosis requires caref step-by- carefulstep planning. The first thing to do is to define preciselywhat you are up against. Having used lesion scoringand oocyst counting to determine that coccidio coccidiosis isthe most probable cause of your broilerperformance, there are still many ques questions thathave to be addressed.1. Is the primary cause of the problem a coccidiosis challenge which is simply too high for the birds to tolerate?2. Or is the outbreak caused by interinter-current (immuno- compromising) diseases?3. Is the level of anticoccidial in th feed too low? the4. Are poor management standards a factor?5. Is the problem localized or is it wide wide-spread?6. Is there a ‘real’ problem or are you looking at ‘normal’ seasonal fluctuations?Only by finding answers to these and other questions can you identify andimplement best possible solutions.However, the problem often lies in the area of product selection. A good place tostart is to evaluate the available products and ensure the best ones for yourparticular requirements are used in the most effective way.Studying the historical surveys of programmes and products used in the broilerintegration will teach a lot. It will give a very good indication of which productsneed to be rested for a while, and which products can be used again. The efficacy ofanticoccidials, or in other words the sensitivity of the parasite to the drugs, is very s, vitystrongly related to the intensity with which these products have been used in theintegration over the past few years. Find out how long a specific product wasincluded in the feed, and for how long it was rested each time.Sometimes a sensitivity test can be of help. With a sensitivity test, the performanceof a whole range of products can be evaluated at the same time and comparisonscan be made. These so-called called ‘anticoccidiograms’ will once again tell which Off: A-602, Vasundhra CGHS, Plot no. 16, Sector 6, Dwarka, New Delhi 110075 602, Phone: +91-9871203111 Email: md@innovistaconsulting.com 9871203111 .com
  2. 2. The Marketing Services & Solutions Providerproducts to use and which ones to rest, as long as you keep in mind that they onlyindicate what is going on in lab conditions. They don’t reflect the dynamic changesin coccidial populations, nor the interactions with many other influencing fieldfactors. Indeed, anticoccidiograms on their own are unsuitable for predicting specificanticoccidial performances in the medium and longer term.IonophoresThe main group of poultry feed additives is the polyether antibiotics – commonlycalled ionophores. These products are obtained through fermentation and, so far,six compounds have become available:Monensin, lasalocid, salinomycin, narasin, maduramycin and semduramicin.The mechanism of action of all ionophores is very similar, since they mediatetransport of mono-and divalent cations through the membrane of the parasite,resulting in disturbance of its osmotic balance. According to the precise method ofaction and the chemical structure of the product, ionophores can be divided intothree groups: monovalent (monensin, narasin, salinomycin), monovalent glycoside(maduramycin, semduramicin) and divalent (lasalocid). Each ionophore has itsspecific strengths and weaknesses with regard to its action spectrum and potency.Monensin, narasin and salinomycin are intrinsically more efficacious against Eimeriaacervulina.Synthetic productsThe second group is the synthetic anticoccidials. These are synthesized drugs whichinclude various groups of completely different chemical classes. DOT, Clopidol,Diclazuril and Robenidine have been very useful for shuttle programs.Each synthetic product must be evaluated in order to determine its specificstrengths and weaknesses with regard to the control of coccidiosis, particularlystrains of Eimeria and the potential development of resistance.Nicarbazine marketed in combination with ionophore maduramycin, the brand nameMEGACOX by Innovista Consulting is a potent, broad-spectrum anticoccidialeffective in all Eimeria species causing coccidiosis with a low potential for resistancedevelopment. Megacox can be ideally used during summers and monsoons duringhigh coccidial challenges. The Brand Megacox has been recently launched byInnovista Consulting in the Indian market. Off: A-602, Vasundhra CGHS, Plot no. 16, Sector 6, Dwarka, New Delhi 110075 Phone: +91-9871203111 Email: md@innovistaconsulting.com
  3. 3. The Marketing Services & Solutions ProviderAmprolium is a good anticoccidial for the control of cecal coccidiosis, but is not veryeffective against intestinal species. The product has been on the market for about35 years and is now mainly used as a therapeutic.ROBIDON (Robenidine 10%) is yet another synthetic compound launched byInnovista Consulting in India. ROBIDON is a safe, broad-spectrum anticoccidial, veryuseful during high coccidial challenges and an ideal product for starter programs.Diclazuril, which has been used for long, has potent broad spectrum activity againstall Eimeria spp. Specific resistance induction tests have shown that resistanceagainst E. acervulina strains developed faster than resistance against E. tenella orE. maxima.Choose the right programHaving gained an understanding of the products available, the next step is tocombine the selected and preferred products into the right anticoccidial program. Todo this effectively, one must have enough information about the efficacy profile ofthe various anticoccidials used in his integration/company.In general, it can be said that a more balanced use of ionophores and syntheticproducts is needed for your future anticoccidial programs. These programs shouldnot be built on just a few products. All the available anticoccidials are useful in thecontrol of coccidiosis. You simply have to know which product to use and when touse it. The first rule is to reserve the strongest product for the periods of highestrisk of coccidiosis.The sheer number of available products allows broiler producers to achieve bestresults from the use of product combinations and shuttle programs. The wide choiceof chemical entities also allows you to rest certain anticoccidials while still usingother products.Plan periods of restThe secret here is to plan a long rest period for each product used. Management ofanticoccidial resistance development means that the use of each product iscontrolled and that, at the same time, sufficiently long rest periods are respected forall products. The objectives of such planning exercise are to obtain a certain dilution Off: A-602, Vasundhra CGHS, Plot no. 16, Sector 6, Dwarka, New Delhi 110075 Phone: +91-9871203111 Email: md@innovistaconsulting.com
  4. 4. The Marketing Services & Solutions Providerof the resistant Eimeria strain into a more sensitive population, and to enable eachproduct to regain at least part of its overall efficacy.Remember that anticoccidial shuttle programs are almost always targeted at the‘average’ farm within a particular integration. For some farms they will workextremely well, but for a few they may be less effective. A rational shuttle programshould be based on the following: Low challenge Early infection Early immunity stimulation Optional protection Compensatory growth No damageBattle and warsCoccidiosis will never be eradicated, but important progress has been made incontrolling the damage resulting from coccidiosis infection in poultry. The strengthof the anticoccidial program and the speed and level of protective immunity seem tobe the most important ones, but the quality of broiler management on the farmshould not be underestimated.Please send your queries to:Dr. Sekhar Basak,Managing Director,Innovista ConsultingEmail: md@innovistaconsulting.com Off: A-602, Vasundhra CGHS, Plot no. 16, Sector 6, Dwarka, New Delhi 110075 Phone: +91-9871203111 Email: md@innovistaconsulting.com

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