Your SlideShare is downloading. ×
Transport Of Oxygen 2
Upcoming SlideShare
Loading in...5

Thanks for flagging this SlideShare!

Oops! An error has occurred.


Saving this for later?

Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime - even offline.

Text the download link to your phone

Standard text messaging rates apply

Transport Of Oxygen 2


Published on

Published in: Technology, Business

1 Like
  • Be the first to comment

No Downloads
Total Views
On Slideshare
From Embeds
Number of Embeds
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

No notes for slide


  • 1. Transport of Oxygen 2 The Bohr effect Fetal haemoglobin Myoglobin
  • 2. Transport of Oxygen 2
    • Hb is even more efficient that suggested by the dissociation curve
    • The amount of O 2 carried by Hb depends not only on the p O 2 but also the partial pressure of carbon dioxide .
  • 3. Transport of Oxygen 2
    • At the tissues there is high [carbon dioxide] this reduces Hb affinity for oxygen so it gives it up.
    • Conversely at lungs there is low [carbon dioxide] so the Hb has a greater affinity for oxygen – so picks up more.
  • 4.  
  • 5.
    • The result is thus, that under the same blood pO 2 conditions, high levels of CO 2 (acidic conditions) will unload more O 2 from the Hb
    • Oxyhaemoglobin releases its oxygen where it is most needed: to the actively respiring tissues.
    Transport of Oxygen 2
  • 6. Transport of Oxygen 2
    • The further the dissociation curve moves to the right, the more readily Hb gives up its oxygen.
  • 7. Transport of Oxygen 2
    • The further the dissociation curve moves to the left, the more readily Hb picks up oxygen.
  • 8. Fetal haemoglobin
    • The developing fetus obtains oxygen from its mum
    • Fetal and maternal blood run close together but never mix
    • This allows materials to diffuse from the blood of mum into the fetus and vice versa. .
  • 9. Fetal haemoglobin
  • 10. Fetal haemoglobin
    • The dissociation curve of fetal Hb is to the left of adult Hb
    • This means fetal Hb combines with oxygen more readily than adult Hb
    • Fetal Hb has a higher affinity for oxygen.
  • 11. Fetal haemoglobin
    • At the placenta the fetal haemoglobin can ‘steal’ oxygen form the maternal haemoglobin.
  • 12. Myoglobin
    • In muscle there is another oxygen binding molecule called myoglobin .
    • Oxymyoglobin is much more stable than oxyhaemoglobin
  • 13. Myoglobin
    • Myoglobin will only give up its oxygen at very low oxygen partial pressures.
  • 14.  
  • 15. Myoglobin
    • The myoglobin dissociation curve is a long way to the left of Hb.
    • At each partial pressure of oxygen, myoglobin holds onto much more oxygen than Hb.
  • 16. Myoglobin
    • This enables myoglobin to act as an oxygen store.
    • Usually respiring muscle will get its oxygen from oxyhaemoglobin
    • Only if the partial pressure of oxygen falls very low will oxymyoglobin release its oxygen