Slideshow Transcript

1. Slide 1:Management of Sepsis Luca Bigatello, MD Director, Surgical ICU, Massachusetts General Hospital Associate Professor of Anesthesia, Harvard Medical School
2. Slide 2: Definitions q Sepsis: proven or suspected infection, with a systemic response (fever, tachycardia, tachypnea, leukocytosis) q Severe sepsis: sepsis, with organ dysfunction q Septic shock: severe sepsis, with hypotension despite adequate fluid resuscitation Bone et al., Crit Care Med ‘92 SCCM/etc., Crit Care Med ‘03
3. Slide 3: Sepsis & Septic Shock Hotchkiss & Karl, NEJM ‘03 q 750,000 septic ICU pts. per year q > 200,000 die, slightly more than all deaths from acute coronary syndromes q Leading cause of death in ICU pts.
4. Slide 4:q Early intervention: