Cozart Drug Of Abuse

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  • 1. DRUG OF ABUSE (DOA) SARVESH KAUSHIK Diagnostics Specialist Delhi City Pool - Cozart® Plc, UK
  • 2. What is DoA???
    • A drug that is taken for nonmedicinal reasons (usually for mind-altering effects); drug abuse can lead to physical and mental damage and (with some substances) dependence and addiction.
                                                         
  • 3. DOA: Main Product Line
    • Amphetamine
    • Barbiturates
    • Benzodiazepines
    • Cannabinoids
    • Cocaine metabolite
    • Fentanul
    • LSD
    • DL Methadone
    Morphine Opiates Pethidine Phencyclidine Promazine Tricyclics Cotinine - differentiates smokers & non-smoker
  • 4. DOA: Sample Types
    • Blood
    • Ocular fluid
    • Oral Fluid
    • Post-mortem blood
    • Serum
    • Sweat
    • Tissue homogenates
    • Urine
  • 5. Classification of Drugs
    • Stimulants - Cocaine,Amphetamines,Methcathinone,
    • Methylphenidate, Anorectic Drugs
    • Depressant - Benzodiazepines, Meprobamate, Gamma Hydroxybutyric -
    • Acid, Barbiturates, Flunitrazepam
    • Hallucinogens - LSD ,MDMA (Esctasy) , Peyote & Mescaline
    • Narcotics - Morphine, Heroin, Hydrocadome, oxycodone, codeine
    • Cannabis - Marijuana, Tetrahydro-cannabinol , Hashish
  • 6.
    • A specialist medical diagnostics company particularly active in the field of point of care and laboratory drug testing.
    • On Site Products
      • COZART DDS
      • COZART Rapid Solids
      • COZART Rapid Urine
    • Laboratory Testing
      • COZART MICROPLATE EIA
      • COZART SpinLab DOA liquid EIA reagents
    Cozart DOA: Brief introduction
  • 7. Drug Detection System - DDS
    • Cozart® DDS
    • The Cozart® Drug Detection System (DDS) is an enhanced on-site saliva drug detection system. With sampling taking approximately 30 seconds and results for the presence of up to 6 different drugs being displayed in under 5 minutes and 2 drugs in under 90 seconds, the Cozart® DDS system is the fastest most reliable drug testing instrument currently available worldwide.
    • All of the kits are manufactured by Cozart under BS EN ISO 9001:2000 and ISO 13485:2003 Quality Management Systems and are CE marked.
                                           .
  • 8. DDS – Features (On Site Saliva)
    • Sample Presence Indicator
    • Guarantee collection of sufficient sample volume.
    • Rapid
    • 2 drug Class in 90 seconds
    • 5 drug classes in 5 minutes
    • Accurate- In any drug testing environment.
    • Simple – sample collection in less than one minute.
    • Rapid detection of Five Drug classes, within five minutes, from a single oral fluid sample
  • 9. DoA Market Scenario: India
    • Market Size:
    • Market Growth:
    • Market Segments:
    • Traditional Clinical Diagnostic Market (Mkt to be served by Merck)
    • Non-Traditional Market: Traffic Police, Sports Authority of India, Customs Dept., Forensic Labs., Airports Authority of India.
  • 10. Cozart ® Rapid Solids
    • Cozart ® Rapid Solids tests offer you the opportunity to test for the presence of illicit drugs in powders, tablets, resins, liquids and on surfaces, without the costs or inconvenience of a laboratory submission.
    • Additional benefits of the Cozart ® Rapid Solids tests are:
    • Sensitive, able to detect the presence of drugs in a sample at levels of 1 part/million
    • Fast, visual results in 2 minutes
    • Improved health & safety as no hazardous chemicals or glass vials to break
    • Easy and straightforward to use
    • Highly cost effective in comparison to laboratory screening
    • As reliable and accurate as laboratory screening Tests are available for:
    • Opiates (Heroin)
    • Methamphetamine
    • Cannabis
    • Cocaine
    • Amphetamine
    • Benzodiazepine
  • 11. Cozart® Rapid Urine
    • Cozart® Rapid Cozart's on-site product portfolio now includes rapid on-site urine tests, applicable in a variety of drug testing situations including workplace, rehabilitation, criminal justice and health care environments .
    • Fully integrated test panel and cup
    • Simultaneous detection of multiple drug classes
    • Temperature label, to verify the sample is at body temperature
    • Key unlocks sample and initiates the test
    • Security Seal
    • Multiple Drug Test Panel
    • Detection of multiple drug classes from a single sample
    • Dip panel in urine then read results
  • 12. RUDT- Drug Panel
    • Multiple Drug Test Cup (includes integrated test panel, cup and key)
    Two-drug panel - Morphine (Opiates), Cocaine
    • Six-drug panel - Amphetamine, Benzodiazepines, Cocaine, Morphine (Opiates), MDMA, Methadone .
    • Amphetamine, Benzodiazepines, Cocaine, Morphine (Opiates), MDMA, THC
    • Amphetamine, Benzodiazepines, Cocaine, Morphine (Opiates), THC, Methadone.
    • Benzodiazepines, Cocaine, Morphine (Opiates), Methadone, THC, Buprenorphine . .
    Ten-drug panel - Amphetamine, Barbiturates, Benzodiazepines, Cocaine, Morphine (Opiates), Methamphetamine, Methadone, THC, Phenycyclidine, Tricyclic Antidepressants. Amphetamine, Barbiturates, Benzodiazepines, Cocaine, Morphine (Opiates), Methamphetamine, Methadone, THC, Phenycyclidine, Buprenorphine.
  • 13. Details of Drugs in RUDT Single Drug Test Strip or Cartridge Simple, Rapid, one step test Clear visible results. Built in procedural controls Product Configurations Multiple drug Test Panels Four-drug Panel – Amphetamine, Benzodiazepines, THC, Morphine (Opiates) Six-drug Panel - Amphetamine, Benzodiazepines, THC, Morphine (Opiates), MDMA, Cocaine Seven-drug Panel – Amphetamine, Benzodiazepines, THC, Morphine (Opiates), MDMA, Cocaine, Buprenorphine Ten-drug Panel - Amphetamine, Benzodiazepines, THC, Morphine (Opiates), MDMA, Cocaine, Buprenorphine, Methadone, Tricyclic Antidepressants, Propoxyphene Single Panel Tests Amphetamine Benzodiazepines Barbiturates Cocaine THC MDMA Opiates Methadone Phencyclidine MDMA Tricyclic Antidepressants Buprenorphine
  • 14. Cozart® Microplate EIA
    • Cozart® Microplate EIA kits provide excellent performance, reproducibility and sensitivity in a simple and standardised procedure. Kits use break-apart wells to allow variable work loads to be accommodated, whilst also offering users the flexibility to run multiple assays per plate. Kits can be run manually or can be fully automated to suit all laboratory requirements. Results are read at 450nm with a plate reader. Cozart Microplate EIA kits contain all reagents necessary to run the assay including a full set of calibrators / standards *.
    * Fentanyl, Pethidine, Promazine and Tricyclics Microplate EIA Kits do not contain calibrators. Detect a broad range of analytes
  • 15. Cozart® Drugs availiable for EIA
    • Amphetamine
    • Barbiturates
    • Benzodiazepines
    • Benzodiazepines specific (N45) Buprenorphine
    • Cannabinoids
    • Cocaine Metabolite
    • Cotinine
    • Fentanyl 7-Amino Flunitrazepam
    • Fluoxetine
    • LSD
    • Methadone
    • Methamphetamine / MDMA
    • Morphine Specific Opiates
    • PCP Pethidine
    • Promazine Tricyclics ………………… More are availiable on Request
  • 16. Cozart® Spinlab® DoA Liquid Reagents Automated homogenous liquid EIA reagents for drugs of abuse detection in oral fluid and urine samples. Oral Fluid and Urine Reagents Highly Sensitive Compatible with all Chemistry reagents No special Extraction required The new oral fluid test kits are optimized to measure in the parts per billion range and are the first homogenous kits to meet the low detection limits dictated by the sample type. A key component of the system is a new oral fluid collection device, the Cozart® Oral Swab that ensures these low levels of drug are not lost during collection. The Cozart® Oral Swab provides a quick and convenient method of obtaining a sample (average sample collection of 1mL in under one minute), and allows easy processing and testing at the laboratory.
  • 17. Drugs for DoA Liquid Reagents
    • Extensive Range of  Drug groups
    • Alcohol
    • Amphetamine*
    • Barbiturates
    • Benzodiazepines
    • Cocaine metabolite*
    • Cotinine*
    • Ecstasy*
    • Methadone*
    • Methadone metabolite
    • Opiates*
    • Oxycodone
    • PCP
    • Propoxyphene
    • THC (cannabis)*
  • 18. How the Market is Structured in India?
    • Dealer driven sales –
      • Rapid Diagnostics Pvt. Ltd. – Rapid urine tests from Acon, Aspen Labs, Alfa Scientific.
      • Mainly done by Private Pathology Labs., Hospitals and CROs.
    • No company focusing exclusively on DoA testing
    • No brand recall amongst customers for DoA
  • 19.
    • Private Laboratories – ‘A’ class labs mainly testing by Rapid Diagnostic tests, using urine as a specimen.
    • Corporate Hospitals – Fully Automated systems (Roche, Abbott, etc)
    • Govt. Hospitals – sending specimens to reference labs*. (*SRL Ranbaxy, Metropolis, Thyrocare, Dr. Lal Path Labs, Vimta etc.)
    • Police Forces – No independent testing at present, sending specimens to Premier Govt. Labs. Like Central Forensic Sciences Lab., New Delhi, Kolkata, Hyderabad (CFSL)
    • Workplace – No laws exist at present .
    Who is doing what?
  • 20. Future Expectation & Trends
    • Sports Authority of India – Compulsory DoA testing for all
    • Workplace – DoA testing becoming compulsory part of pre-employment screening
    • Workplace – DoA testing to be used as an aid in performance review in Corporate sector – particularly in fields where physical activity is involved – e.g. Services – Army, Navy, Air Force, Police, Healthcare sector, Sports etc .
    • Traffic Police - Stringent norms for driving - surprise checks on Traffic signals, highways (e.g. Breath Analyzers at J. J. Hospital Flyover in Mumbai to detect Alcohol)
    • To avoid accidents, Generating revenue for Traffic Dept.
    • Common Wealth Games—2010 , New Delhi
  • 21. Customer Mapping
    • EIA- Target Customer
    • Private Hospitals
    • Private Diagnostic Centers
    • Medical Colleges
    • Biotech Colleges & Toxicology Deptt.
    • CRO’S
    • Rapid Urine Test:-
    • Private Labs
    • Sports Authority of India
    • Forensic Labs
    • Narcotics Deptt.
    • Traffic Deptt.
    • More intrestingly………….Chemists & Physicians
  • 22. Customer Mapping
    • Drug Detection System :-
    • Forensic Labs
    • Corporate Hospitals
    • Sports Authority of India
    • Traffic Deptt.
    • Narcotics Deptt.
    • Clinical Research Organisations
    • Prsions Services
  • 23. Competitors: Companies, Prices & Pack Sizes.
  • 24. Launch Plan
  • 25. Market of Interest: Product-Market Mix
    • EIA, Urine Rapid Tests, EMIT - To start with traditional diagnostic market:
    • CROs
    • Reference labs. (WellSpring Diagnostics, SRL Ranbaxy, Metropolis, Thyrocare, Dr. Lal Path Labs, Vimta etc.)
    • Private Labs.
    • Private Hospitals (Escorts, Batra, DHLI etc…
    • Corporate Hospitals (Apollo, Max Healthcare, Fortis Healthcare, etc)
    • University — JNU,Hamdard,South Campus , PGIMS ,CDRI ,SMS Jaipur etc…
    • R&D Centres - Ranbaxy , Panacea , Dabur, NAPIER ….etc..
  • 26. Market of Interest: Product-Market Mix
    • DDS - Non-Traditional Markets like :
    • Traffic Police
    • Sports Authority of India
    • Govt. Customs Dept.
    • Govt. Forensics Depts.
    • Shipping Corporation of India
    • Airports Authority of India
  • 27. Any laws currently applied for DoA testing?
    • Sports Authority of India – Governed by Govt. laws, no specific information.
    • Road Testing – None
    • Workplace – None
  • 28. Business Collaboration with Cozart Group
    • Exclusivity for India.
    • MERCK has a best fit for COZART Products as it deals into similar market for last 18 years.
    • Focus on Immunology (already dealing into EIA)
    • Strategic Focus on DoA testing.
    • All India presence – Large Dealer Network (32 nos.) and complimentary sales force (6 zones, 1 Regional Sales Manager , 5 Area Managers, 34 Product Specialist / Diagnostic - Total 40 nos.)
  • 29. Any Questions? Or Any Answers?
  • 30.
    • ThAnK yOu