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21    V S 223  The  Endocrine  System
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21 V S 223 The Endocrine System

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  • 1. The Endocrine System VS 223 Dr. Noland
  • 2. Endocrine Glands • Secrete their product directly into bloodstream • Known as “ductless” glands
  • 3. Hormones • Act on target organs due to specific receptors located on the target plasma membrane
  • 4. Neuroendocrine Reflex • Nerve input on the afferent end • Hormonal input on the efferent end • Suckling reflex • Induced ovulation in cats, rabbits
  • 5. Endocrine Glands • Discrete gland - Adrenal gland • Organ – Duodenum • Combo of Exocrine/Endocrine - Pancreas
  • 6. Classification of Hormones • Peptides – chains of amino acids –Most hormones • Amines – tyrosine derivatives –Catecholamines, T4 • Steroids – cholesterol derivatives –Gonadal hormones and adrenal cortical hormones
  • 7. Mechanisms of Action • Hormones circulate in the bloodstream and bind with target organ cell receptors to affect a change in the target cell
  • 8. Hydrophilic Hormones Peptides and Catecholamines
  • 9. Lipophilic Hormones Steroids and Thyroid
  • 10. Hormonal Action
  • 11. Feedback Regulation