Hudson Zen Bev

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  • 1. Restful Nights and Cheerful Days from Food Sourced Tryptophan
  • 2. Tryptophan Isolated in 1901 Sir Frederick Hopkins
  • 3. Tryptophan & Serotonin Tryptophan Step 1 + OH Step 2 -COOH Serotonin
  • 4. Tryptophan Metabolism Is Light Dependent Tryptophan Serotonin Melatonin
  • 5. Control Mechanisms in Melatonin Synthesis Pineal Gland
    • Pineal Cells
    • Similar in structure to retinal cells
    • Secrete melatonin at night
    • Secrete serotonin in the day
  • 6. Julius Axelrod
  • 7. Melatonin-Serotonin & Light Serotonin Superiour Cervical Ganglion Melatonin Supra Chiasmatic Nucleus
  • 8. Melatonin-Serotonin & Light Serotonin Superiour Cervical Ganglion Melatonin Supra Chiasmatic Nucleus
  • 9. 5-HydroxyTryptophan 5-HTP Tryptophan Step 1 + OH Step 2 -COOH Serotonin
  • 10. Tryptophan Usage/ 100,000 population (NEJM 1990)
    • Prior to FDA ban 2% of American Households used tryptophan in a regular basis
    • The sales growth curve was exponential
  • 11. Tryptophan Ban
    • FDA based on cases of EMS
    • Before and after Showa Denka product
    • Genetics play a role?
    • Contamination plays a role?
    • Most likely some combination of genetics & contamination
  • 12. Tryptophan Available From Natural Sources But...
    • Protein Sources Rich in Tryptophan decrease brain tryptophan levels.
  • 13. BBB (Blood Brain Barrier)
  • 14. Transport Sites
  • 15. Transport Sites
  • 16. Transport Sites (Sites occupied)
  • 17.
    • In fact a high protein meal increases blood levels of tryptophan but lowers brain levels
    Tryptophan level Serotonin level
  • 18.
    • Carbohydrates prompt the pancreas to create insulin
    • Insulin reduces the blood level of all amino acids except for tryptophan
    • Tryptophan levels rise relative to other amino acids
    Carbohydrate
  • 19. = Insulin
  • 20.
    • Carbohydrates reduce blood levels of all amino acids except for tryptophan
  • 21. Finding the right protein
  • 22. + =
  • 23.
      • Zenbev increases the serotonin level in the brain
      • With Zenbev, brain levels of tryptophan go up as blood levels go up
    Zenbev Tryptophan = Anxiety level Serotonin level
  • 24. At night, serotonin turns into melatonin Increase in serotonin Melatonin =
  • 25. Sleep Study Nutritional Neuroscience Chronic Insomnia RestBites Tryptophan + Carbohydrate Carbohydrate
  • 26. Protein Source Tryptophan versus Pharmaceutical Grade Tryptophan as an Efficacious Treatment for Chronic Insomnia
  • 27. Anxiety Study Canadian Journal Of Physiology & Pharmacology Social Phobia RestBites Carbohydrate
  • 28. Protein-source tryptophan as an efficacious treatment for social anxiety disorder: a pilot study
  • 29. Eat 1 chocolate ½ hour before bedtime. Try this for three nights and if required, increase by 1 chocolate until the desired effect is achieved.
    • 90 calories per square
    • Low Fat (2.5 g)
    • 0 Trans Fats
    • Caffeine Free
    • Low Sodium
  • 30. Ingredients: Partially Defatted Deoiled Organic Pumpkinseed Flour, Organic Agave Nectar, Sugar, Chocolate Coating, Caramel, Sunflower Oil, Water, Agar, Soybean Oil, Soy Lecithin – Caffeine Free
  • 31. FAQ’s
    • What if I take Zenbev during the day, will I get sleepy?
    • Can’t I just eat some pumpkin seeds?
    • Why does this have Dextrose in it?
    • I took some Zenbev last night and I did not sleep any differently. Why?
    • What is the difference between this and l-tryptophan?
    • Is this different than the tryptophan that was banned a couple of years ago?
  • 32. Amide Form Amine Form
  • 33. Benefits
    • Promotes Deep, Restful Sleep and Daytime Calm
    • No Hangover effect in the morning
    • Return to sleep easily after waking up in the night
    • No risk of dependence or tolerance
    • Replace Daytime Stress with a sense of calm control
    • Organic Ingredients
    • Clinically Proven effective
    • Patented product