• Share
  • Email
  • Embed
  • Like
  • Save
  • Private Content
Blood Physiology 1
 

Blood Physiology 1

on

  • 49,429 views

Blood Physiology: General Consideration; Plasma; Cellular Elements of the Blood

Blood Physiology: General Consideration; Plasma; Cellular Elements of the Blood

Statistics

Views

Total Views
49,429
Views on SlideShare
46,800
Embed Views
2,629

Actions

Likes
69
Downloads
0
Comments
39

40 Embeds 2,629

http://nursinglectures.blogspot.com 1706
http://philippinenurses.blogspot.com 406
http://www.slideshare.net 109
http://pinoyrn.blogspot.com 102
http://www.nursinglectures.blogspot.com 49
http://www.pinoyrn.blogspot.com 47
http://www.ustudy.in 37
http://nursinglectures.blogspot.com.au 25
https://tasks.crowdflower.com 24
http://nursinglectures.blogspot.in 22
http://puff-teaching.blogspot.ca 15
http://nursinglectures.blogspot.ca 14
http://statichtmlapp.heroku.com 12
http://puff-teaching.blogspot.com 10
http://nursinglectures.blogspot.co.uk 7
http://www.nursinglectures.blogspot.in 5
http://translate.googleusercontent.com 5
http://nursinglectures.blogspot.co.il 4
http://nursinglectures.blogspot.sg 3
http://nursinglectures.blogspot.co.nz 3
https://learningedge.edgehill.ac.uk 2
http://nursinglectures.blogspot.it 2
http://blackboard.butte.edu 2
http://cbs-elearning.sixent.com 2
https://tusk.cotse.com 1
https://education.blackboard.com 1
http://ustudy.in 1
http://72.14.253.104 1
http://nursinglectures.blogspot.hu 1
https://learning.ulster.ac.uk 1
https://bransonschoolonline.blackboard.com 1
http://nursinglectures.blogspot.hk 1
http://wildfire.gigya.com 1
http://nursinglectures.blogspot.com.br 1
http://nursinglectures.blogspot.fi 1
http://www.clearspring.com 1
https://2hide.net 1
http://eduonline.mayo.edu 1
http://fronter.com 1
http://nursinglectures.blogspot.kr 1
More...

Accessibility

Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel

110 of 39 previous next Post a comment

  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
  • I am impressed in reading this power point. very well prepared, may i get this presentation as i am expecting at the earliest. Thank you!
    Are you sure you want to
    Your message goes here
    Processing…
  • Good. please send me this copy >> nookpawee@hotmail.com.
    thank you very much.
    Are you sure you want to
    Your message goes here
    Processing…
  • AMIR SHEHZAD AWESOME LACTURE FROM LIAQUAT NATIONAL MEDICAL COLLEGE KARACHI
    Are you sure you want to
    Your message goes here
    Processing…
  • oh sheet i need it ..............
    Are you sure you want to
    Your message goes here
    Processing…
  • hi how to get the file
    k-al3etra@hotmail.com
    ineed all about blood
    Are you sure you want to
    Your message goes here
    Processing…

110 of 39 previous next

Post Comment
Edit your comment

Blood Physiology 1 Blood Physiology 1 Presentation Transcript

  • Blood Physiology Rodolfo T. Rafael, M.D.,CFP http://clinical-updates.blogspot.com [email_address] +639212147558
  • Blood Physiology
    • General Consideration
    • Plasma
    • Cellular Elements of the Blood
  •  
  • General Consideration
    • unicellular organisms
      • nutrition and excretion
      • volume of the extracellular environment greatly exceeds that of the cell
    • multicellular organisms
      • specialized tissue
  • Unicellular Organism
  • Functions of the Blood
    • homeostasis
    • respiratory function
    • nutritive function
    • excretory function
    • transport internal secretions
    • helps maintain acid-base balance
    • maintenance of water and electrolyte imbalance and in regulation of colloid and total osmotic pressure
    • immunity to disease and protect the body against bacteria
    • regulation of the body temperature
  • Composition of the Blood
    • Plasma
    • Formed Elements
  • Plasma
    • Water
    • Plasma proteins
    • Blood sugar
    • Lipids
    • Inorganic salts
    • Special Plasma Substances
    • Gases
  • Water
    • 91-92%
  • Plasma Proteins
    • liver
    • albumin, globulin, fibrinogen, and prothrombin
    • Function
      • maintenance of water balance
      • Imparts a viscosity to the blood
      • sources of antibodies
      • blood clotting
      • maintain acid-base balance
  • Blood Sugar
    • glucose
    • source of energy
  • Lipids
    • neutral fats, cholesterol, and phospholipids
    • supply energy or stored as fat
  • Inorganic Salts
    • Calcium ions and the Sodium ions
    • Salt ions (chlorides, bicarbonates, phosphates, sulfates) Electrolytes (sodium, calcium, potassium, and magnesium)
    • Calcium ions and phosphates
    • Iodides and Iron
  • Special Plasma Substances
    • hormones
    • enzymes
    • clotting elements
    • antibodies
    • urea
    • uric acid
    • creatinine
  • Gases
    • oxygen
    • carbon dioxide
    • nitrogen
  • Formed Elements
    • Red Cell or Erythrocytes
    • WBC or Leucocytes
    • Blood Platelets or Thombocytes
  • Red Blood Cell
    • Description
    • Normal Values
    • Red Cell Production
    • Red Blood Cell Destruction
    • Osmotic Fragility
    • Function of Erythrocytes
  • Description
    • biconcave discs, 2µm thick 8 μ m in diameter
    • deformable (PGE 1 , PGE 2 )
    • carry hemoglobin in circulation
      • 1 liter- 3ml of dissolved O 2
      • hemoglobin can transport 70 times this amount
      • 20 ml of O 2 = 100ml of blood
    • non- nucleated
  •  
  •  
  •  
  • Normal Values
    • Men 5-6 x 10 12 /L of blood
    • Women 4-5 x 10 12 /L of blood
    • Infants 6.5 x 10 12 /L of blood
    • Hemoglobin
      • 120- 150g/L (female)
      • 140-170g/L (male)
    • Erythrocyte (Hct)
      • 0.38- 0.48 (female)
      • 0.40- 0.50 (male)
  • Red Cell Production
    • yolk sac of the embryo
      • few weeks
    • liver, spleen, lymph node
      • middle trimester
    • bone marrow of skull, vertebrae, ribs, sternum
      • later part of pregnancy
  • Erythropoiesis Hemocytoblast basophil erythroblast polychromatophil erythroblast normoblast reticulocyte erythrocytes
  • FeedBack Control
    • inhibited
      • supernormal level
    • stimulated
      • anemia
      • hypoxemia
    • controlled
      • erythropoetin
  • Hypoxemia kidney liver REF Globulin Erythropoietin Stem cells Erythrocytes
  • Red Blood Cell Destruction
    • Life span
      • 120 days
    • Destruction
      • 2.5M/sec
      • 1% of red cells/day
    • Spleen
    • Mechanical and Chemical stresses
      • friction
  • Osmotic Fragility
    • hypertonic solution
    • hypotonic solution
    • isotonic solution
    • Fragility Index
      • 0.45-0.38% NaCL
      • 0.36- 0.30% NaCl
  • Primary Function of Erythrocytes
    • transport hemoglobin
      • carries oxygen
      • carbon dioxide
  • White Blood Cell
    • Description
    • Classes of Leucocytes
    • Normal Values
    • Origin
    • Life span
    • Function of Leucocytes
  • Description
    • nucleated
  •  
  • Classes of Leucocytes
    • non-granular
      • lymphocytes
      • monocytes
    • granular
      • neutrophils
      • basophils
      • eosinophils
  • Normal Values
    • WBC 5-10 x 10 9 /L of blood
    • basophils 0.005
    • eosinophils 0.02-0.04
    • stabs 0.02 – 0.04
    • segmenters 0.45- 0.65
    • lymphocytes 0.20- 0.35
    • monocytes 0.02- 0.06
  • Origin
    • granular
      • red bone marrow
    • non- granular
      • lymphatic tissue (lymph nodes, tonsils, payer’s patches, spleen and thymus)
  • Life span
    • Granulocytes
      • two weeks
    • Large lymphocytes
      • 2-3 days
    • small ones
      • 100-200 days
  • Function of Leucocytes
    • Neutrophils
      • phagocytic
    • Lymphocytes
      • non phagocytes
        • immune reactions
        • antibodies
        • tissue transplant
    • Monocytes
      • phagocytic
      • combating chronic infection
  • Monocytes arrive at the site of infection few organelles form these organelles small granules rough endoplasmic reticulum ribosomes synthesize enzymes used to digest material ingested by monocytes
  • Eosinophils
      • phagocytic
      • allergic reaction
    Antibody react with antigen inactivate it eosinophil gets rid of inactivated complex
  • Basophils
      • heparin
      • phagocytes
  • Blood Platelets
    • Description
    • Normal Values
    • Origin
    • Life span
    • Functions
  • Description
    • small
    • colorless bodies
    • 2-4 microns in diameter
  • Normal Values
    • 200-400 x 10 9 /L
    • thrombocytopenia
  • Origin
    • megakaryocytes
  •  
  • Life Span
    • 4-5 days
  • Function
    • white thrombus or a platelet plug
    • thromboplastin  essential for blood coagulation
    • Serotonin
    • Helps in clot retraction
  • Platelet Aggregation
    • occurs before clotting
    • agglutination on platelets depend on several factors:
      • rate of flow
      • size of the blood vessel
      • character of the vessel wall
      • presence of ADP
  • P A ADP Acts as local hormone Cause rapid platelet aggregation Calcium Platelet Adhere +
  •  
  • Thank You! For Not Listening