1. Sugar in the primordial soup The formose reaction and the origin of life
2. Content <ul><li>Life from the Soup </li></ul><ul><li>Proteins versus RNA </li></ul><ul><li>Prebiotic syntheses of amino acids & nucleobases </li></ul><ul><li>Prebiotic synthesis of sugars </li></ul><ul><li>Sugar in space </li></ul><ul><li>Conclusion </li></ul>
3. Life on Earth 4.6 10 9 yrs ago – Formation of Earth 3.5 10 9 yrs ago – Prokaryotic organisms Now 1.2 10 9 yrs ago – Eukaryotic organisms 0.7 10 9 yrs ago – Multicellular organisms Prebiotic
4. What started life? What compounds were present in the beginning? What compounds/reactions are required now?
5. The primordial ”soup” CO 2 N 2 CO SO 2 CH 2 O CH 4 Note: no photosynthesis - no O 2 ! NH 3 HCN CH 3 CN CH 2 CHCN HCCCN NCCN H 2 O
36. Conclusion The basic building blocks of proteins and RNA can be prepared from compounds expected to be present on early Earth. The conditions to make them are incompatible, i.e. they can not be formed under the same reaction conditions and in the same place. The strongest proof that they could have been formed prebiotically is their presence in extraterrestrial matter.