About Percy Julian <ul><li>Percy Julian was known as the “soy bean chemist” for his success in making new drugs & chemicals from soy-bean and other plants. </li></ul>
Percy Julian was born in Montgomery, Alabama, on April 11, 1899
College & graduate education U. of Vienna BA (1920) Harvard U. . AM (1923) PhD (1931) DePauw U. .
Ph.D. University of Vienna, 1934 At Vienna Percy found his lifelong interest in the synthesis of nature’s complex molecules K.T. Finley
Synthesis of physostigmine In 1934 at DePauw University Percy Julian synthesized physostigmine from the amino acid, tryptophan.
Dr.Julian’s inventions from soy bean protein <ul><li>Latex paints (Glidden’s Speed Satin) </li></ul><ul><li>Fire-fighting foam (AeroFoam) </li></ul><ul><li>Water-resistant paper coatings </li></ul>Soy beans Encyclopedia Britannica, 1999
AeroFoam fire extinguisher International Fire Service Training Association, 1992 How Foam Works <ul><li>Separates </li></ul><ul><li>Smothers </li></ul><ul><li>Cools </li></ul><ul><li>Suppresses </li></ul>
Extraction of soy bean sterols <ul><li>Solid alcohols for synthesis of: </li></ul><ul><ul><li>progesterone </li></ul></ul><ul><ul><li>testosterone </li></ul></ul><ul><ul><li>cortisone </li></ul></ul>
Sex hormones from soy beans Courtesy of Dr. Hutcheon, 1999 OH O H 3 C O CH O Progesterone Testosterone
Synthesis of cortisone <ul><li>Dr. Julian is known for his synthesis of cortisone which is used to fight arthritis & other ailments of the connective tissues. </li></ul>
Julian process for synthesis of cortisone Diosgenin 16-dehydropregnenolone Compound S Cortisone Hydrocortisone Julian process LC Mills, 1965
Julian Laboratories in Franklin Park Photo courtesy of Jennings Miller
Honors & awards <ul><li>Elected to National Academy of Sciences in 1973 </li></ul><ul><li>Spingarn Award of NAACP in 1947 </li></ul><ul><li>Procter Prize in Chemistry by Sigma Xi in 1974. </li></ul>Photo at Sigma Xi Awards Ceremony
Percy Julian Centennial 1999 <ul><li>Faith Julian, Vernon Jarrett, & Percy Julian, Jr. at Percy Julian Centennial on April 11, 1999. </li></ul><ul><li>Photo by Lee Balgemann </li></ul>
Finale <ul><li>Percy Lavon Julian was born in 1899 & he died in 1975. </li></ul><ul><li>He was one of our greatest chemists. </li></ul><ul><li>May his legacy live on! </li></ul>
Anand N, Bindra JS, Ranganathan S: Art in Organic Synthesis 2nd ed. New York: Wiley, 1988. Fox MA, Whiresell JK: Organic Chemistry. 2nd ed. Boston: Jones & Bartlett, 1997. Julian PL, Cole JW, et al. Sterols XIII. Chemistry of the adrenal cortex steroids. Recent Progress in Hormone Research , Vol vi, 1951. Witkop, Bernard: Percy Lavon Julian: April 11, 1899-April 19, 1974. (sic). In: Biographical Memoirs of the National Academy of Sciences . Vol. 52. Washington, 1980. References. 1. 2. 3. 4. .
Acknowledgements Section on Computer Science Oak Park & River Forest High School Oak Park, Illinois Earl Austria Mary Confray-Polk Duncan Hutcheon Joan Kotas Tom McCoy Jennings Miller Norbert Teclaw Donald Vogl