ZRANB2

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    ZRANB2 - Presentation Transcript

    1. ZRANB2 — a transcriptional regulator? Richard P. Grant MMB, Sydney Thursday, 11 September 2008 1
    2. Splicing • Splicing ubiquitous in eukaryotes • ~70% human genes are alternatively spliced • Aberrant splicing causes genetic disease, e.g. - DMD - CF Thursday, 11 September 2008 2
    3. Consensus sequences direct splicing Exon 1 Intron 1–2 Exon 2 Thursday, 11 September 2008 3

    + rpg7ssrpg7ss, 2 years ago

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    Talk given at the MRC-LMB, Cambridge on 29 Aug 08

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