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Morepen api

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  • 1. - API - Product List S. No. Product Innovator’s Product Details DMF status Brand Name 1 Aliskiren Hemifumerate Tekturna Renin inhibitor -- 2 Atorvastatin Calcium Amorphous Lipitor Chloesterol Lowering USDMF, EDMF 3 Atorvastatin Calcium Crystalline Lipitor Chloesterol Lowering USDMF, EDMF 4 Desloratadine Clarinex Antihistaminic USDMF, EDMF 5 Eletriptan hydrobromide Relpax Antimigraine -- 6 Ezetimibe Zetia Antihyperlipoproteinemic -- 7 Fexofenadine Hydrochloride Allegra Antihistaminic EDMF 8 Linezolid Zyvox Antibacterial Tech. Package 9 Loratadine Claritin Antihistaminic USDMF, CEP 10 Montelukast Sodium Singulair Antiasthmatic EDMF 11 Paracetamol Tylenol Antipyretic Tech Package 12 Pioglitazone Hydrochloride Actos Antidiabetic USDMF, EDMF 13 Prasugrel Effient Platelet inhibitor -- 14 Rosuvastatin Calcium Crestor Antihyperlipoproteinemic;HM -- G CoAReductase Inhibitor 15 Telmisartan Micardis Antihypertensive Tech. Pacakage 16 Valsartan Tereg Antihypertensive, -- Biphenyltetrazole derivatives 17 Voglibose Basen Antidiabetic Under developmentNote: The above products are not for sale where the Patents are applicable & still valid. Intermediates-Product List S. No. Product Chemical Name of Intermediate Intermediate CAS No. Code 1 Montelukast Methyl-[E]-3-[3-[2-(7-chloro-2-quinolinyl) ethenyl] MTN6 149968-11-6 phenyl]-3-oxo-propyl]benzoate Methyl-[E]-2-[3S-[3-[2-(7-chloro-2-quinolinyl) ethenyl] MT7 181139-72-0
  • 2. phenyl] -3-hydroxy propyl] benzoate [(S)-(E)]-2-[3-[3-[2-(7-chloro-2-quinolinyl) ethenyl] phenyl] MT8 142569-70-8 -3-hydroxypropyl]-phenyl-2-propanol 1-(hydroxymethyl)cyclopropyl acetonitrile MTS2 152922-71-9 1-(Mercaptomethyl) cyclopropane acetic acid MTS4 162515-68-6 (1-mercaptomethyl) cyclopropane methyl acetate MTS5 152922-73-12 Loratadine 2-Cyano-3-(3-chlorophenethyl)pyridine L5 31255-57-9 8-Chloro-10, 11-dihydro-4-aza-5H-dibenzo (a, d) L7 31251-41-9 cycloheptan-5-one (1-Methyl-4-piperidinyl)[3-(2-3-chlorophenyl)ethyl-2- LN8 130642-50-1 pyridinyl] methanone hydrochloride 11-(N-Methyl-4-piperidinyl)-8-chloro-11-hydroxy- 6,11- L8 38089-93-9 dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine 11-(N-Methyl-4-piperidinylidene)-8-chloro-6,11- L9 / LH9 38092-89-6 dihydro-5H-benzo(5,6)cyclohepta (1,2-b) pyridine3 Fexofenadine 4-(cyclopropylcarbonyl)-α,α-dimethyl benzene acetic acid D8 162096-54-0 2-(4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1- D10 or FD3 154477-55-1 oxobutyl)phenyl)-2,2-dimethylacetic acid methyl ester4 Carvedilol 4-(2,3-Epoxypropoxy)carbazole CD3 51997-51-45 Lamotrigine 2-(2,3-Dichlorophenyl)-2-(guanidinyamino)acetonitrile LMG01 84689-20-36 Pioglitazone (±)5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4- PG4 105355-26-8 thiazolidinone 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4- PGN3 144809-28-9 thiazolidinedione7 Telmisartan 2n-Propyl-4-methyl-6-(1-methyl benzimidazole-2-yl)- TL06 152628-02-9 benzimidazole8 Risperidone 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H- RB03 93076-03-0 pyrido[1,2-a]pyrimidin-4-one hydrochloride 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole RA04 84163-13-3 hydrochloride9 Linezolid (R)-N-[[3-[3-fluoro-4-morphonilyl]phenyl]-2-oxo-5- LZ04 168828-82-8 oxazolidinyl]methanol (R)-N-[[3-[3-fluoro-4-morphonilyl]phenyl]-2-oxo-5- LZ06 168828-84-0 oxazolidinyl]azide (R)-N-[[3-[3-fluoro-4-morphonilyl]phenyl]-2-oxo-5- LZ07A Not Available oxazolidinyl] methyl amine10 Atorvastatin 4-Fluoro-Alpha-[2-methyl-1-oxopropyl]-Gamma-oxo-N- AT-3 125971-96-2 Beta-diphenyl benzene Butanamide (4R-Cis)-1,1-Dimethylethyl-6-cyanomethyl-2,2- AT-6 125971-96-2 dimethyl-1,3-Dioxane -4-Acetate (4R-Cis)-1,1-Dimethylethyl-6-[2-[2-(4-Fluorophenyl)-5-(1- Isopropyl)-3-phenyl-4-[(Phenylamino)carbonyl]1H- pyrrol-1-yl]Ethyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetate AT-8 125971-95-111 Aliskiren (R)-4-(2-(chloromethyl)-3-methylbutyl) -1-methoxy-2-(3- AL06 324763-39-5 methoxypropoxy)benzene 3-isovaleroyl-4(R)-benzyl-oxazolidin-2-one ALS01 145589-03-312 Rosuvastatin 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N- RT08 147118-37-4 methylsulfonyl) amino]pyrimidinyl-5-yl-carbaldehyde13 Quetiapine Dibenzo[b,f] [1,4]thiazepine-11(10H) one QT02 3159-07-714 Eletriptan 5-Bromo-3-(N-methylpyrrolidin-2(R)–yl methyl)-1H-indole EL03 143322-57-0
  • 3. Note: The above intermediates are not for sales where the Patents are applicable & still valid. Intermediates under DevelopmentS. No. Product Name Stage CAS No. Chemical Name1 Aliskiren ALN01 173336-76-0 4-Bromo-1-methoxy-2(3-methoxypropoxy) benzene ALN07 Not Available (2S,7S)-2-isopropyl-7-{4-methoxy-3-(3- methoxypropoxy)bezyl}-8-methylnonayl-N,N- dimethylformamide ALN08 Not Available (S)-2-[(S)-2-bromo-2-((2R,4S)-4-isopropyl-5-oxo- tetrahydrofuran-2-yl)-ethyl-1-[3-(3-methoxy propoxy)-4- methylphenyl] -3-methylbutyl ester ALN10 Not Available (2S,4S,5S,7S)-5-azido-4-hydroxy-2-isopropy-7-[4- methoxypropoxy)-benzyl]-8-methyl nonanic acid (2- carbamoyl-2-methyl propyl) amide AL10 Not Available 2(S)-(tert-butoxycarbonyl)amino-4(S)-isopropyl-5-(p-tert- butyl-phenyl)-pentanal.2 Ezetimibe EB02 Not Available (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxy pentanoyl]-4- phenyl-1,3- oxazolidin-2-one EB03 Not Available (S)-3-{(R)-2-[(S)-4-(trimethylsilyloxy)-phenyl]-(4- fluorophenylamine)-methyl -4-[2-(4-fluorophenyl)-(1S)- trimethyl silyloxy]-butyric}-4-phenyl-oxazolidine-2-one
  • 4. EB04 Not Available (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3- (4-fluorophenyl)-3-(trimethylsilyloxy) propyl]-4-(4- (trimethylsilyloxy)phenyl)-2-azetidinone EZ04 Not Available (3R,4S)-1-(4-Fluorophenyl)-3-[3-(hydroxy)-3- oxopropyl]-4-(4-benzyloxyphenyl)-2-azetidonone3 Eletriptan EL06 Not Available 5-[2-(Benzene sulfonyl)ethenyl]-3-(1-methyl pyrrolidin-2(R)yl methyl)-1H-indole4 Linezolid LZN04 Not Available (5R)-5-(chloromethyl)-3-[3-fluoro-4-(4- morpholinyl)phenyl]-2-oxazolidinone LZN05 Not Available (S)-N-[[3-[3-Fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5- oxazolidinyl]methyl]pthalamide5 Quetiapine QTS01 13349-82-1 1-[2-(2-Hydroxyethoxy) ethyl]piperazine6 Valsartan -- 195435-23-5 (R)-3-Methyl-2-(N-((2`-(2-trityl -2H-tetrazol-5- yl)biphenyl-4-yl) methyl)pentananamido) butanoic acid OR Trityl valsartan -- 137863-20-8 N-[2`-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl- (L)-valine benzyl ester OR Valsartan benzyl ester7 Ziprasidone Int -I 118289-55-7 5-(2-chloroethyl)-6-chlorooxindole Int - II 144010-02-6 3-(1-Piperazinyl)-1,2- benzisothiazole hydrochlorideNote: The above intermediates are not for sales where the Patents are applicable & still valid.

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