Published on

Published in: Technology, Health & Medicine
  • Be the first to comment

  • Be the first to like this

No Downloads
Total views
On SlideShare
From Embeds
Number of Embeds
Embeds 0
No embeds

No notes for slide


  1. 1. 1 Publikationsverzeichnis PD Dr. Andreas Barthel 1. Jarry H, Dietrich M, Barthel A, Giesler A, Wuttke W: In vivo demonstration of a paracrine, inhibitory action of Met-enkephalin on adrenomedullary catecholamine release in the rat. Endocrinology 125: 624-629 (1989) (Impact factor: 4.8) 2. Nickel W, Huber LA, Kahn RA, Kipper N, Barthel A, Fasshauer D, Söling HD: ADP ribosylation factor and a 14-kD polypeptide are associated with heparan sulfate-carrying post-trans-Golgi network secretory vesicles in rat hepatocytes. J Cell Biol. 125: 721-732 (1994) (Impact factor: 14.0) 3. Nickel W, Kipper N, Barthel A, Kahn RA, Fasshauer D, Söling HD: ARF and VAPP14: two proteins involved in the delivery of heparan sulfate proteoglycan from the trans-Golgi network to the plasma membrane. Ann NY Acad Sci. 733: 344-356 (1994) (Impact factor: 1.4) 4. Barthel A, Nickel W. Tonko C, Söling HD: Sorting and budding of constitutive secretory vesicles in hepatocytes and hepatoma cells. Adv Enzyme Regul. 35, 283-292 (1995). (Impact factor: 2.3) 5. Barthel A, Leonhardt U, Stöckmann F, Ramadori G: Individual therapeutic procedure in metastatic carcinoid of the small intestine. Leber Magen Darm 26, 164-169 (1996) (Impact factor: 0.3) 6. Barthel A, Kohn AD, Luo Y, Roth RA: A constitutively active version of the Ser/Thr kinase Akt induces production of the ob gene product, leptin, in 3T3- L1 adipocytes. Endocrinology 138, 3559-3562 (1997) (Impact factor: 4.8) 7. Barthel A, Nakatani K, Dandekar AA, Roth RA: Protein kinase C modulates the insulin-stimulated increase in Akt1 and Akt3 activity in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 243, 509-513 (1998) (Impact factor: 3.1) 8. Kohn AD, Barthel A, Kovacina KS, Boge A, Wallach B, Summers SA, Birnbaum MJ, Scott PH, Lawrence JC Jr, Roth RA: Construction and characterization of a conditionally active version of the serine/threonine kinase Akt. J Biol Chem. 273, 11937-11943 (1998) (Impact factor: 7.4) 9. Dandekar AA, Wallach BJ, Barthel A, Roth RA: Comparison of the signaling abilities of the cytoplasmic domains of the insulin receptor and the insulin receptor-related receptor in 3T3-L1 adipocytes. Endocrinology 139, 3578- 3584 (1998) (Impact factor: 4.8)
  2. 2. 2 10. Liao J, Barthel A, Nakatani K, Roth RA: Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene. J Biol Chem. 273, 27320-27324 (1998) (Impact factor: 7.4) 11. Barthel A, Okino ST, Liao J, Nakatani K, Li J, Whitlock JP Jr, Roth RA: Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1. J Biol Chem. 274, 20281-20286 (1999) (Impact factor: 7.4) 12. Nakatani K, Thompson DA, Barthel A, Sakaue H, Liu W, Weigel RJ, Roth RA: Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem. 274, 21528-21532 (1999) (Impact factor: 7.4) 13. von der Crone S*, Deppe C*, Barthel A*, Sasson S, Joost HG, Schürmann A. Glucose deprivation induces Akt-dependent synthesis and incorporation of GLUT1, but not of GLUT4, into the plasma membrane of 3T3-L1 adipocytes. Eur J Cell Biol. 79: 943-949 (2000) (Impact factor: 2.8) *Der Beitrag der markierten Autoren ist gleichwertig 14. Woods YL, Rena G, Morrice N, Barthel A, Becker W, Guo S, Unterman TG, Cohen P: The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site. Biochem J. 355:597- 607 (2001) (Impact factor: 4.3) 15. Schmoll D, Grempler R, Barthel A, Joost HG, Walther R: Phorbol ester- induced activation of mitogen-activated protein kinase/extracellular-signal- regulated kinase kinase and extracellular-signal-regulated protein kinase decreases glucose-6-phosphatase gene expression. Biochem J. 357: 867- 873 (2001) (Impact factor: 4.3) 16. Barthel A, Schmoll D, Krüger KD, Bahrenberg G, Walther R, Roth RA, Joost HG: Differential regulation of endogenous glucose-6-phosphatase and phosphoenol-pyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. Biochem Biophys Res Commun. 285: 897-902 (2001) (Impact factor: 3.1) 17. Barthel A, Krüger KD, Roth RA, Joost HG: Concentration-dependent stimulatory and inhibitory effect of troglitazone on insulin-induced fatty acid synthase expression and protein kinase B activity in 3T3-L1 adipocytes. Naunyn Schmiedebergs Arch Pharmacol. 365:290-295 (2002) (Impact factor: 2.9)
  3. 3. 3 18. Bahrenberg G, Behrmann I, Barthel A, Hekermann P, Heinrich PC, Joost HG, Becker W: Identification of the critical sequence elements in the cytoplasmic domain of leptin receptor isoforms required for JAK/STAT activation by receptor heterodimers. Mol Endocrinol. 16:859-872 (2002) (Impact factor: 6.3) 19. Barthel A, Schmoll D, Krüger KD, Roth RA, Joost HG: Regulation of the forkhead transcription factor FKHR (FOXO1a) by glucose starvation and AICAR, an activator of AMP-activated protein kinase. Endocrinology 143:3183-3186 (2002) (Impact factor: 4.8) 20. Barthel A, Orth HM, Krüger KD, Schmoll D, Joost HG: Construction and characterization of a conditionally active construct of the insulin-regulated forkhead transcription factor FKHR. Exp Clin Endocrinol Diabetes 110:304- 309 (2002) (Impact factor: 1.4) 21. von Groote-Bidlingmaier F, Schmoll D, Orth HM, Joost HG, Becker W, Barthel A: DYRK1 is a coactivator of FKHR (FOXO1a)-dependent glucose-6- phosphatase gene expression. Biochem Biophys Res Commun. 300:764- 749 (2003) (Impact factor: 3.1). 22. Kortylewski M, Feld F, Krüger KD, Bahrenberg G, Roth RA, Joost HG, Heinrich PC, Behrmann I, Barthel A: Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism. J Biol Chem. 278:5242-5249 (2003) (Impact factor: 7.4). 23. Barthel A, Joost, HG: Insulin receptor. In: Offermanns S, Rosenthal W (eds.), Encyclopedic Reference of Molecular Pharmacology. Springer Verlag New York-Berlin-Heidelberg. (2003). 24. Leder S, Czajkowska H, Mänz B, de Graaf K, Barthel A, Joost HG, Becker W: Alternative splicing variants of the protein kinase DYRK1B exhibit distinct patterns of expression and functional properties. Biochem J. 372:881-888 (2003) (Impact factor: 4.6). 25. Barthel A, Scherbaum WA, Bornstein SR: Novel aspects in the mechanisms of steroid diabetes and the regulation of hepatic glucose production by insulin and steroids. Med Klin. 98:283-286 (2003) (Impact factor: 0.3). 26. Barthel A, Schmoll D: Novel concepts in insulin regulation of hepatic gluconeogenesis. Am J Physiol Endocrinol Metab. 285:E685-E692 (2003) (Impact factor: 3.3). 27. Ehrhart-Bornstein M, Lamounier-Zepter V, Schraven A, Langenbach J, Willenberg, HS, Barthel A, Hauner H, McCann SM, Scherbaum WA, Bornstein SR: Human adipocytes secrete mineralocorticoid releasing factors. Proc Natl Acad Sci USA. 100:14211-14216 (2003) (Impact factor: 10.7).
  4. 4. 4 28. Orth HM, Krüger KD, Schmoll D, Grempler R, Scherbaum WA, Joost HG, Bornstein SR, Barthel A: Regulation of endogenous glucose-6-phosphatase gene expression by protein kinase B (PKB) and the forkhead transcription factor FKHR (FOXO1a) in hepatoma cells. Reg Peptides 121:19-24 (2004) (Impact factor: 3.1). 29. Grempler R, Kienitz A, Werner T, Meyer M, Barthel A, Ailett F, Sutherland C, Walther R, Schmoll D: Tumor necrosis factor alpha decreases glucose-6- phosphatase gene expression by the activation of nuclear factor kappaB. Biochem J. 382:471-479 (2004) (Impact factor: 4.6). 30. Kortylewski MT, Barthel A: STAT-3 and the liver: a new STATion on our way to understand diabetes? Hepatology 40:1008-1010 (2004) (Impact factor: 9.8). 31. Bornstein SR, Zacharowski P, Schumann RR, Barthel A, Nguyen T, Papewalis C, Rettori V, McCann SM, Schulze-Osthoff K, Scherbaum WA, Tarnow J, Zacharowski K: Impaired adrenal stress response in Toll-like receptor 2 deficient mice. Proc Natl Acad Sci USA. 47:16695-16700 (2004) (Impact factor: 10.7). 32. Barthel A, Bornstein SR: Images in clinical medicine. Obstructive lingual thyroid. N Engl J Med. 352:e1 (2005) (Impact factor: 38.6). 33. Schinner S, Barthel A, Dellas C, Grzeskowiak R, Sharma SK, Oetjen E, Blume R, Knepel W: Protein Kinase B activity is sufficient to mimic the effect of insulin on glucagon gene transcription. J Biol Chem. 280:7369-7376 (2005) (Impact factor 6.4). 34. Barthel A, Herzig S, Müller HW, Harborth J, Bornstein SR: RNA interference- based strategies for metabolic syndrome treatment. Horm Metab Res. 37:59- 62 (2005) (Impact factor 1.9). 35. Barthel A, Klotz LO: PI 3-kinase signalling in the cellular stress response. Biol Chem. 386:207-216 (2005) (Impact factor 3.6). 36. Barthel A, Schmoll D, Unterman TG: FoxO proteins in insulin action and metabolism. Trends Endocrinol Metab. 16:183-189 (2005) (Impact factor 9.1). 37. Schinner S, Scherbaum WA, Bornstein SR, Barthel A: Molecular mechanisms of insulin resistance. Diabet Med. 22:674–682 (2005) (Impact factor 2.6).
  5. 5. 5 38. Korenblum W, Barthel A, Licinio J, Wong ML, Wolf OT, Kirschbaum C, Bornstein SR: Elevated cortisol levels and increased rates of diabetes and mood symptoms in Soviet Union-born Jewish immigrants to Germany. Mol Psychiatry 10:974-5 (2005) (Impact factor 6.9). 39. Grempler R, Gunther S, Steffensen KR, Nilsson M, Barthel A, Schmoll D, Walther R. Evidence for an indirect transcriptional regulation of glucose-6- phosphatase gene expression by liver X receptors. Biochem Biophys Res Commun. 338:981-986 (2005) (Impact factor 2.9). 40. Barthel A, Herzig S, Schmoll D: Forkhead proteins and regulation of hepatic gene expression. In: Friedman JE (ed): New transcription factors and their roles in diabetes and its therapy. Advances in Molecular and Cellular Endocrinology, 189-212, Elsevier (2006). Buchbeitrag 41. Walter P, Kampkötter A, Eckers A, Barthel A, Schmoll D, Sies H Klotz LO: Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions. Arch Biochem Biophys. 454:107-113 (2006) (Impact factor 3.2). 42. Barthel A, Walter P, Kampkötter A, Klotz LO: Regulation of PI 3-kinase dependent signalling mechanisms by copper and zinc. Arch Biochem Biophys. (2007) (Impact factor 3.2). 43. Walter P, Barthel A, Steinbrenner H, Klotz LO: Selenoprotein P expression is stimulated by Foxo1a transcription factor in human hepatoma cells. (eingereicht - 2006).