BEST METHOD FOR MIRACLE




                                                        Introduction
                         ...
In-vitro Fertilization
In 1978 the first baby was born courtesy of the in vitro fertilization
technique developed by Dr. R...
there are too many embryos developing, the patient may forgo the second
hormone injection. Multiple pregnancies largely le...
conclusion that many women arrive at because in the long run it costs less
financially as well as emotionally.
Dr. Glieche...
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Introduction

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Introduction

  1. 1. BEST METHOD FOR MIRACLE Introduction In-vitro Fertilization Ovulation Induction Comparative Study Conclusion Introduction Ideally women want to finish college and be settled in a job earning enough money before they start a family. However, by the time this occurs women are in their mid thirties heading towards forty and decreased fertility. “The biological reality is that a woman’s fertility decreases by about 10 percent from age 31 to 34 and from age 34 to 39 it decreases an additional 40 percent,” according to David Adamson, M.D a reproductive endocrinologist from California. Afterwards, things just continue to deteriorate and the woman needs more than her husband’s help to start a family. As a consequence, the couple has to turn to fertility treatments. There are many variations and selections of these, two of which are ovulation stimulation and in vitro fertilization (IVF). The latter has become the most popular form recently.
  2. 2. In-vitro Fertilization In 1978 the first baby was born courtesy of the in vitro fertilization technique developed by Dr. Robert G. Edwards, a British scientist. Since then there have been a million more such births as the technique has been improved. In vitro fertilization involves fertilizing the egg outside of the body in a petri dish or test tube (hence the term test tube baby) and then re- implanting the fertilized egg into the female. Since not all fertilized eggs attach to the uterine wall, two or more eggs are put into the female to increase the chances of pregnancy. This leads to one of the big disadvantages… that of multiple births. Before, the decision of how many eggs to transfer to the female was left up to the physician but the American Society for Reproductive Medicine (ASRM) recently recommended that no more than three embryos should be placed in a woman under 35 years of age. Ovulation Induction Ovulation induction is an internal method. The woman receives hormone injections that cause eggs to ripen and be released for fertilization. According to a study reported in the New England Journal of Medicine, the doctor then has no control over the number of embryos that result. He tries to determine how many embryos are present by measuring a hormone that maturing eggs release or through the use of ultra sound to detect large follicles. The study proved that these methods of detection weren’t very dependable and that multiple births can still result, especially in women younger than forty. Figure1 shows that as a woman gets older the changes of her getting pregnant is significantly decreased. If
  3. 3. there are too many embryos developing, the patient may forgo the second hormone injection. Multiple pregnancies largely lead to premature births and possible long-term handicap. Figure 1 Odds of a Birth in Relation to the Woman's Age, Number of Eggs Fertilized, and Number of Embryos Transferred. Comparative Study Medical Director of the Center for Human Reproduction in New York; Dr. Norbert Gliecher led the study. It was aimed at finding a way to decrease multiple births. According to the New England Journal report, the doctor and his colleagues examined 3,347 attempts to help 1,494 infertile women over a 2 ½ year span. The group of women was treated with the ovulation induction method and 441 became pregnant. The pregnancies included 88 sets of twins, 22 triplets, 10quadruplets, five quintuplets and two sextuplets. The study concluded that IVF is a better option than the ovulation induction method. Since in vitro fertilization method provides less chance of multiple births, then it should follow that women would select it…not so, because there is the large factor of cost to consider. In vitro fertilization sets the would-be mother back $10,000 on average: a figure quoted in the study. This figure is about three times more than the cost of ovulation induction. On the other hand, women are willing to pay the extra expense. “If it’s a good clinic where the doctor is really achieving successful in vitros, I’d bite the financial bullet and go for the IVF,” said one 30 year-old woman who lost an ovary and tried to get pregnant for over six years. This is the
  4. 4. conclusion that many women arrive at because in the long run it costs less financially as well as emotionally. Dr. Gliecher noted that ovulation stimulation has a 15 percent pregnancy rate and an uncontrollable risk, while IVF has a 40 percent pregnancy rate and absolute control. Consequently, it is small wonder why many women with fertility issues choose IVF. However, age also is a factor; the study group was relatively young. Ovulation induction doesn’t result in as many multiple births in women in their late 30s and older. As stated before, as a woman ages, her fertility decreases therefore she is less likely to have a great chance of getting pregnant. That is, the less the possibility of the woman becoming pregnant, the less likely she will have multiple births from ovulation induction. Conclusion Multiple births have been held up as glamorous but it can be a real nightmare for the woman and prove fatal to many neonates that are often born premature. A woman needs to consider her age when deciding to have children using a fertility method. We see celebrities in their forties having children and we hear about 60 year-olds having a child however we seldom hear about the trials they went through. Furthermore, those individuals only make up about two percent of the population. They are the exception, not the rule. It is important that the woman talks over all the possibilities with her physician if she is intent on having her biological child. Webliography American Society for Reproductive Medicine (ASRM) Common Fertility Procedures New England Journal of Medicine Other Interesting Article on In vitro Fertilization High Rate of Multiple Births Associated With Infertility Treatments Can Be Reduced Fertility Techniques Increase Births ... and Risks Return to top

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