George P. Chrousos, MD


                           CURRICULUM VITAE




I.     Biographical Information                  ...
George P. Chrousos, M.D.




I.     BIOGRAPHICAL INFORMATION

NAME:                                   George P. Chrousos, ...
George P. Chrousos, M.D.


      2.    1975 Educational Council for Foreign Medical Graduates (ECFMG); Standard Certificat...
George P. Chrousos, M.D.


       16.   1999 June     Professor of Pediatrics, Athens University Medical School (elected)
...
George P. Chrousos, M.D.


            1997   The J. Lester Gabrilove Lecture, Mount Sinai Medical School, New York, NY,
 ...
George P. Chrousos, M.D.


      Memorial Endowment Committee, Mortimer B. Lipsett Memorial Fund, The Endocrine Society, B...
George P. Chrousos, M.D.


      Editor-in-Chief, Neuroimmunomodulation (2002- 2006)
      Endocrinology Consultant, Stedm...
George P. Chrousos, M.D.




                           George P. Chrousos, MD


                                PUBLICATI...
George P. Chrousos, M.D.


A.      ORIGINAL ARTICLES

1.      Musliner T., Chrousos G.P., Amos H. (1977) Transport Enhance...
George P. Chrousos, M.D.


        Corticotropin Releasing Factor on the Anterior Pituitary Function of Stalk-Sectioned Cy...
George P. Chrousos, M.D.


31.     Pugeat M., Chrousos G.P., Nisula B., Loriaux D.L., Brandon D.D., Lipsett M.B. (1984) Pl...
George P. Chrousos, M.D.


        Arginine Vasopressin (AVP) Secretion Following the Antiglucocorticoid RU 486: Dose-resp...
George P. Chrousos, M.D.


59.     Weiss S.R.B., Post R.M., Gold P.W., Chrousos G.P., Sullivan T.L., Walker D., Pert A. (1...
George P. Chrousos, M.D.



73.      A., Pickar D., Doran A., Wolkowitz O., Gallucci W., Chrousos G.P., Gold P.W. (1986) N...
George P. Chrousos, M.D.


        Pharmacokinetic Properties of the Antiglucocorticoid and Antiprogesterone Steroid of RU...
George P. Chrousos, M.D.


101.    Berrettini W.H., Nurnberger J.I. Jr., Zerbe R.L., Gold P.W., Chrousos G.P., Tomai T. (1...
George P. Chrousos, M.D.


        G.B. Jr., Loriaux D.L. (1988) Gadolinium DPTA Enhanced MR Imaging of ACTH-Secreting
   ...
George P. Chrousos, M.D.


        Rat. Endocrinology 125: 1067-1073.

131.    Calogero A., Gallucci W.T., Chrousos G.P., ...
George P. Chrousos, M.D.


        of the "Peripheral" Benzodiazepine Receptor System to Hypothalamic pituitary-adrenal Fu...
George P. Chrousos, M.D.


        Hormone Secretion In Vitro is Stimulated by Interleukin-1 in an Eicosanoid-dependent Ma...
George P. Chrousos, M.D.


        (1992) Effects of Carbamazepine on Pituitary-adrenal Function in Healthy Volunteers. J....
George P. Chrousos, M.D.


186.    Marini J.C., Bordenick S., Heavner G., Rose S., Hintz R., Rosenfeld R., Chrousos G.P. (...
George P. Chrousos, M.D.


        P.W. (1992) Central Hypothyroidism is Associated with Advanced Age in Male Fischer 344/...
George P. Chrousos, M.D.


        Pituitary-Adrenal Axis of Black and White Women. J. Clin. Endocrinol. Metabol. 77:536-5...
George P. Chrousos, M.D.


        190:59-64.

228.    Zeiger M.A., Fraker D.L., Pass H.I., Nieman L.K., Cutler G.B. Jr., ...
George P. Chrousos, M.D.


        (1994) Local Secretion of Corticotropin Releasing Hormone by Enterochromafin Cells in H...
George P. Chrousos, M.D.


255.    Bernadini R., Chiarenza A., Kamilaris T.C., Renaud N., Lempereur L., Demitrack M., Gold...
George P. Chrousos, M.D.


268.    Karalis K., Crofford L., Wilder R.L., Chrousos G.P. (1995) Glucocorticoid and/or Glucoc...
George P. Chrousos, M.D.


        Kindreds and Linkage to the Short Arm of Chromosome 2. J. Clin. Invest. 97:699-705.

28...
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
George P. Chrousos, MD
Upcoming SlideShare
Loading in …5
×

George P. Chrousos, MD

3,743
-1

Published on

0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
3,743
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
9
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide

George P. Chrousos, MD

  1. 1. George P. Chrousos, MD CURRICULUM VITAE I. Biographical Information p. 2 II. Academic Honors and Awards p. 3 III. Membership in Professional and Scientific Organizations p. 5 IV. Membership in Committees - Editorial Boards - Society Boards p. 5
  2. 2. George P. Chrousos, M.D. I. BIOGRAPHICAL INFORMATION NAME: George P. Chrousos, M.D. PRESENT ADDRESS: Aiolou 12 Athens, Greece 15 342 DATE AND PLACE OF BIRTH: July 18, 1951; Patras, Greece CITIZENSHIP: United States, Greece DEGREES: M.D., Athens University, Faculty of Medicine, Athens, Greece, 1975 Sc.D., Athens University, Athens, Greece, 1977 Doctor Honoris Causa, Liege University, Liege, Belgium, 2003 Doctor Honoris Causa, Universita Politechnica delle Marche, Ancona, Italy 2006 BOARD CERTIFICATION: American Board of Pediatrics, 1980 American Board of Pediatric Endocrinology, 1980 Greek Specialty Title in Pediatrics, 1980 Greek Specialty Title in Endocrinology, 1981 POSITIONS HELD: Senior Investigator Developmental Endocrinology Branch (1981 - 1989) National Institute of Child Health and Human Development, NIH Chief, Pediatric Endocrinology Section Developmental Endocrinology Branch (1989 - 1999) National Institute of Child Health and Human Development, NIH Chief, Pediatric and Reproductive Endocrinology Branch (1999-2001), National Institute of Child Health and Human Development, NIH Professor and Chairman, First Department of Pediatrics, Athens University Medical School (2001- ) POSTGRADUATE TRAINING 1975-1980 1. 1975-1976 Research Fellow, Laboratory of Microbiology and Immunology, Athens University, Athens, Greece. 2. 1975-1976 Resident, First Department of Internal Medicine, Athens University, Faculty of Medicine, Athens, Greece. 3. 1976-1978 Resident, Department of Pediatrics, New York University Medical Center, New York, NY. 4. 1978-1981 Clinical Associate, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, NIH, Bethesda, Maryland. CERTIFICATION AND LICENSURE 1. 1975 License to practice Medicine in Athens, Greece 2
  3. 3. George P. Chrousos, M.D. 2. 1975 Educational Council for Foreign Medical Graduates (ECFMG); Standard Certificate. 3. 1977 Federation of State Licensure Examination (FLEX). License to practice in Massachusetts, Maryland, Virginia and District of Columbia. ADMINISTRATIVE DUTIES • Director, NICHD/Georgetown University Training Program in Pediatric Endocrinology (1988-2002) • Chairman, Medicine and Physiology Department, Foundation for the Advanced Education in the Sciences at the National Institutes of Health (1990-2002) • Chairman, Selection Committee and Acting General Director, Foundation for Biomedical Research (IIBEAA), Athens Academy of Sciences and Letters, Athens, Greece (2001-2002) • Director, Division of Maternal and Child Health, and Member, Board of Directors, Athens University Medical School, Athens, Greece (2004-2005, 2007-) • Director, Division of Endocrinology, Metabolism and Diabetes, Evgenidion Hospital, Athens University Medical School, Athens, Greece (2005- date) II. ACADEMIC HONORS AND AWARDS 1. 1969-1975 "Scholarship of Excellence" awarded by the State Scholarship Institution, Ministry of Education, Greek Government. 2. 1972-1975 Scholarship "A. Papadakis", Athens University, Athens, Greece. 3. 1975 M.D. Degree summa cum laude, Athens, University, Faculty of Medicine, Athens, Greece. 4. 1977 Doctorate Diploma, "Excellent." Athens University, Athens, Greece. 5. 1981-1983 Clinical Assistant Professor of Pediatrics 1983-1985 Clinical Associate Professor of Pediatrics 1985-Date Clinical Professor of Pediatrics, Georgetown University Medical School, Washington, D.C. 6. 1987 June The "Richard E. Weitzman Memorial Award," awarded by the U.S. Endocrine Society "for outstanding research achievements in the fields of endocrinology and metabolism". 7. 1990-Date Adjunct Professor of Physiology and Biophysics, Georgetown University Medical School, Washington, D.C. 8. 1990 Expert Testimony to 101st US Congress 9. 1991 May The "Galen Award", Hellenic American Society for the Health Sciences, Washington, D.C. 10. 1991 July Honorary Faculty, Keio University School of Medicine, Tokyo, Japan 11. 1992 June Superior Service Award, U.S. Public Health Service, "for pioneering studies on the regulation of hypothalamic-pituitary-adrenal axis function, leading to new insights into the pathophysiology of adrenal diseases and novel diagnostic strategies". 12. 1993 October Honorary Faculty, Parma University, Parma, Italy 13. 1997 June The 1997 Endocrine Society Clinical Investigator Award, “for major achievements in clinical investigation”. 14. 1997 July The 1997 Hans Selye Award, Hans Selye Foundation, Montreal, Canada, “for outstanding contributions to stress research.” 15. 1999 June First Prize, 1999 Pharmacia-Upjohn International Award for Excellence in Published Clinical Research awarded by the US Endocrine Society. 3
  4. 4. George P. Chrousos, M.D. 16. 1999 June Professor of Pediatrics, Athens University Medical School (elected) 17. 1999 October The 1999 Novera Herbert Spector Award, International Society for Neuroimmunomodulation, Lugano, Switzerland “for significant contributions in both leadership and research in neuroimmunomodulaton.” 18. 1999 October Certificate of Commendation, American Academy of Pediatrics “for important contributions made to the mission and goals of the Academy and to the children.” 19. 2000 Sept. The 2000 Henning Andersen Prize, European Society for Pediatric Endocrinology, Brussels, Belgium 20. 2000 Nov. Mastership Award, American College of Endocrinology, “for distinction as a role model and as a contributor to the Art and Science of Endocrinology.” 21. 2001 August Certificate of Recognition, Howard Hughes Medical Institute, Teachers and Students Internship Program, Bethesda MD 22. 2001 Nov ISI Highly Cited Researcher in Clinical Medicine, ISI, Philadelphia, Pa. www.ISIhighlycited.com 23. 2001 Nov. Fellow, Japan Health Sciences Foundation, Tokyo, Japan 24. 2002 April Clinical Endocrinology Trust Professor 2002, Sir Edward Sharpey-Schafer Medal, British Endocrine Societies, for “major contributions to Endocrinology and Metabolism” 25. 2003 March Doctor Honoris Causa, University of Liege, Liege, Belgium 26. 2004 July Lifetime Achievement Award, International Society for Psycho-Neuro-Endocrinology, Glasgow, UK for “outstanding scholarship and path-breaking contributions to Psychoneuroendocrinology”. 27. 2004 Dec Distinguished Physician Award, Hellenic Medical Society of New York 28. 2005 April Mastership Award, American College of Physicians, “for significant contributions to the Art and Science of Medicine” 29. 2006 May Doctor Honoris Causa, Universita Politechnica delle Marche, Ancona, Italy 30. 2006 June ISI Highly Cited Researcher in Biochemistry and Biology, ISI, Philadelphia, Pa. www.ISIhighlycited.com 31. 2006 Dec The 2006 Gentle Giant Award, Pituitary Network Association, Rancho Mirage, Ca. “for exceptional services above and beyond in the study of pituitary diseases” 32. 2007 April The 2007 Henning Andersen Prize, European Society for Pediatric Endocrinology, Helsinki, Finland 33. 2007 June Symposium on Cortisol Secretion Abnormalities Honoring Dr. George P. Chrousos Horm Metab Res. 2007 Jun; 39(6): 401-3. III. SELECTED NAMED LECTURES 1989 Beth Israel Seminar in Medicine, Harvard University Medical School, Boston, MA; 1989 Israel Macher Memorial Lecture, Albert Einstein College of Medicine, New York, NY; 1990 Christos Choremis Memorial Lecture, Hellenic Pediatric Society Annual Meeting, Thessaloniki, Greece; 1991 Ira Rosenthal Lecture in Pediatrics, University of Illinois, Chicago, IL; 1994 Beth Israel Seminar in Medicine, Harvard University Medical School, Boston, MA; 1994 Millie Schembechler Memorial Conference on Adrenal Cancer, University of Michigan, Ann Arbor, MI; 1995 Mark Dodge Memorial Lecture, University of Kansas and University of Missouri at Kansas City, MO; 1996 Robert Vine Memorial Lecture, Australasian Pediatric Endocrinology Group Annual Meeting, Adelaide, Australia; 1997 Clinical Investigator Lecture, Endocrine Society, Minneapolis, MN; 1997 Hans Selye Memorial Lecture, International Congress of Stress, Budapest, Hungary; 4
  5. 5. George P. Chrousos, M.D. 1997 The J. Lester Gabrilove Lecture, Mount Sinai Medical School, New York, NY, 1998 The Novum Lecture, Karolinska Institute, Huddinge, Sweden, 1998 The 1998 Dennis Ikkos Memorial Lecture, Hellenic Endocrine Society, Athens, Greece. 1999 The 1999 Novera Herbert Spector Lecture, Fourth International Congress of the International Society for Neuroimmunomodulation, Lugano, Switzerland. 1999 The 1999 Novartis Lecture, Canadian Society of Endocrinology and Metabolism, Ottawa, Canada 2000 The 2000 Nicholas Zervas Distinguished Lecture in Neuroendocrinology, Harvard University Medical School, Boston, Massachusetts. 2001 The 2001 George Merikas Memorial Lecture in Medicine, The University of Athens Medical School, Athens, Greece 2001 Commencement Address, The University of Patras Medical School, Patras, Greece 2002 The 2002 Visiting Professor Lecture, British Endocrine Societies, Harrogate, England 2002 The 2002 Keith Harrisson Memorial Lecture, The Endocrine Society of Australia, Adelaide, Australia 2003 The 2003 Dennis Ikkos Memorial Lecture, Hellenic Endocrine Society, Thessaloniki, Greece 2003. Distinguished Lecturer in Stress Biology, Children’s Hospital of Philadelphia, University of Pennsylvania 2006. The 2006 Dennis Ikkos Memorial Lecture, Hellenic Endocrine Society, Athens, Greece 2007. Calouste Gulbenkian Foundation Lecture on “Stress, Inflammation and Well-being”, Lisbon, Portugal 2007. Megaron plus lecture on “Genes, Brain, Stress, and Evolution”, Athens, Greece VI. MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC ORGANIZATIONS American Society for Clinical Investigation (Elected 1989) Association of American Physicians (Inducted 1995) The Society for Pediatric Research (Elected 1985) The American Pediatric Society (Elected 1992) The Endocrine Society Lawson Wilkins Society for Pediatric Endocrinology The Society for Neuroscience American Federation for Clinical Research American Academy of Pediatrics (Fellow) American College of Physicians (Fellow, elected Master 2004) New York Academy of Sciences American Diabetes Association International Brain Research Organization International Society for Psychoneuroendocrinology Molecular Medicine Society (Fellow) European Society for Clinical Investigation (Elected 1995) American College of Endocrinology (Fellow; Master, Elected 2000) European Society for Pediatric Endocrinology (Corresponding Member, Elected 1997) Association of Program Directors in Endocrinology and Metabolism (1998-2002) Fellow, The World Innovation Foundation (2004-) V. MEMBERSHIP IN COMMITTEES - EDITORIAL BOARDS-SOCIETY BOARDS Medical Record Committee (Chairman), Clinical Center, NIH (1990-1997) Pediatric Care Committee, Clinical Center, NIH Clinical Research Review Board, NICHD, NIH NIH Graduate Medical Education Committee 5
  6. 6. George P. Chrousos, M.D. Memorial Endowment Committee, Mortimer B. Lipsett Memorial Fund, The Endocrine Society, Bethesda, Maryland (1984) Education Committee, The Endocrine Society, Bethesda, MD (1990-1993) Editorial Board, Neuro-Endocrin-Immunology (1987-1990) Editorial Board, Journal of Clinical Endocrinology and Metabolism (1992-1995) Editorial Board, NeuroImmunoModulation (1993-2002) Fogarty International Scholars Advisory Panel (1994-present) Editorial Board, Hellenic Medical Journal (1995-present) Consultant, Task Force on SES and Health (1995) and Mind-Body Network (1997, 2001), John and Catherine McArthur Foundation Editorial Board, Endocrinology and Metabolism (1995-1998) Scientific Advisory Board, Institute for Hormone and Fertility Research, University of Hamburg, Germany (1995-present) Editorial Board, Stress (1995-present) Board of Directors, Second World Congress on Stress, Melbourne, Australia 1998 Editorial Review Panel, "Panic, Anxiety, and Stress Disorders" (C.E. Koop, Chairman), Time Life Medical (1995-1997) Editorial Board, Molecular Psychiatry (1995-present) International Advisory Board, Arquivos Brasileiros de Endocrinologia e Metabologia (1996-present) Editorial Board, Metabolism, Clinical and Experimental (1996-present) Editorial Board, Endocrinology (1997- 2000) Medical Advisory Board, Cushing's Support and Research Foundation, Inc. (1996-Present) Public Health/Governmental Affairs Committee (Co-Chair), Pituitary Tumor Network Association (1995- Present) Scientific Advisory Board (Co-Chair), National Adrenal Diseases Foundation, Inc. (1996-Present) Practice Guidelines Subcommittee, American Academy of Asthma, Allergy and Immunology (1997-Present) Editorial Board, Endocrine (1997- ) Committee on Classification of Corticotropin-Releasing Factor Receptors, International Union of Pharmacology (NC-IUPHAR) (1996-1998 ) Basic and Clinical Endocrinology Interest Group at the National Institutes of Health, Co-Chair (1997- ) Advisory Council, Klinefelter Syndrome Association of Canada (1998 - ) Editorial Board, Experimental and Clinical Rheumatology (1998 - ) Editorial Board, Trends in Endocrinology and Metabolism (1998 - ) Editorial Board, Iatriki (1998 - 2000) Editorial Board, Journal of Clinical Endocrinology and Metabolism (1999 - 2002) Board of Directors, International Society for the Investigation of Stress (1999- ) Editorial Board, Encyclopedia of Endocrine Disorders, Academic Press (1999- ) Editorial Board, Endocrine Practice (1999- ) Expert Consultant, Workgroup on Stress and Pre-Term Delivery, Centers for Disease Control, Atlanta, GA. (1999- ) Founding Member and Member of the Board, Association for Patient-Oriented Research (1999- 2002) National Aeronautics and Space Administration (NASA) Life Sciences Standing Panel, Chair (12/1/1999- 11/30/2002) Editorial Board, Current Drug Targets-Immune, Endocrine Metabolic Disorders (CDT-IEMD), (2000- ) Editor-in-Chief, On-line Textbook, Pediatric Endocrinology, www.eMedicine.com Associate Editor, On-line Textbook, Endocrinology and Metabolism, www.endotext.org Special Advisory Committee (Member), Endocrine Journal, The Japan Endocrine Society (2000- ) Editorial Board, Reviews in Endocrine and Metabolic Disorders (2000- ) Board of Directors, Pituitary Network Association (2000- ) Associate Editor, Hormones, Greek Endocrine Society (2001- ) Vice President, Hellenic Society of Pediatric and Adolescent Endocrinology (2001-2006) President, International Society for NeuroImmunoModulation (2002-2005) Editorial Board, Journal of Endocrinological Investigation (2002- ) International Board, The National Institute of Stress Evaluation and Management (2002- ) 6
  7. 7. George P. Chrousos, M.D. Editor-in-Chief, Neuroimmunomodulation (2002- 2006) Endocrinology Consultant, Stedman’s Medical Dictionary (2002- ) Advisory Committee on Science and Technology, Greek Orthodox Archidiocese of America (2002- ) Consensus Statement, Congenital Adrenal Hyperplasia, Lawson Wilkins Pediatric Endocrine Society and European Society for Pediatric Endocrinology, Boston (2002) Board of Counselors, The Suffering Child (2003-) (www.thesufferingchild.net) Consensus Statement on Cushing Syndrome (2002), International Symposium on Cushing Syndrome, Ancona, Italy Consensus Statement on Adrenocortical Carcinoma (2003), International Schembechler Conference on Adrenocortical Carcinoma, University of Michigan, Ann Arbor, Michigan Scientific American, Greek Edition, Scientific Advisory Board (2003- ) Scientific Advisory Board, Research Center of Intensive and Thoracic Medicine, Athens, Greece (2003-) Metabolism Network, Society for Women’s Health, Washington, DC (2003-) Associate Editor, The Encyclopedia of Stress (2004-) Associate Editor, Adolescent Gynecology, Reproduction and Menopause (2004- ) Editorial Board, American Journal of Medicine (2005- ) Editorial Board, Gender Medicine (2005-) Adrenal Insufficiency Task Force, American College of Critical Care Medicine (2005- ) Member of the Council, European Society for Clinical Investigation (2005- ) Member, MEDINE, Medical Education in Europe (2005-) President, Hellenic Society of Pediatric and Adolescent Endocrinology (2006-) President, Hellenic College of Pediatrics (2006-) President Elect, European Society for Clinical Investigation (2008-) Editorial Board, The Journal of Neuroendocrinology (2007-) 7
  8. 8. George P. Chrousos, M.D. George P. Chrousos, MD PUBLICATIONS A. ORIGINAL ARTICLES p. 9-52 B. CHAPTERS, REVIEWS, EDITORIALS p. 52-82 C. BOOKS p. 82-83 8
  9. 9. George P. Chrousos, M.D. A. ORIGINAL ARTICLES 1. Musliner T., Chrousos G.P., Amos H. (1977) Transport Enhancement and Reversal: Glucose and 3-0- Methylglucose. J. Cell. Physiology 91: 155-168. 2. Chrousos G.P., Barnes K.M., Sauer M.A., Loriaux D.L., Cutler G.B. Jr. (1980) 1,9(11)-11- Deoxycortisol: An Improved Antiglucocorticoid. Endocrinology 107: 472-477. 3. Chrousos G.P., Loriaux D.L., Sherins R., Cutler G.B. Jr. (1981) Unilateral Testicular Enlargement Resulting from Inapparent 21-Hydroxylase Deficiency. J. Urol. 126: 127-128. 4. Chrousos G.P., Poplack D., Kostolich M., Wiede C., Oliff A., Brown T., Bercu B. (1981) Hypothalamic- Adenohypophyseal Function in the Rhesus Monkey: A Primate Model. J. Med. Primatol. 10(2): 61-71. 125 5. Chrousos G.P., Wachsclicht-Rodbard H., Adams A., Roth J., Cornblath M. (1981) Increased I- Insulin Specific Binding in Hypoglycemic Infants and Children. Ped. Res. 15: 1345-1347. 6. Wishnick M.M., Valenti Q., Doyle E.F., Balian A., Genieser N., Chrousos G.P. (1982) Churg-Strauss Syndrome: Development of Cardiomyopathy during Corticosteroid Treatment. Am. J. Dis. Child. 136: 339-344. 7. Chrousos G.P., Peck G., Gross E., Cutler G.B. Jr., Loriaux D.L. (1982) Adrenal Function in Women with Idiopathic Acne, J. Invest. Dermatol. 78 (6): 468-471. 8. Chrousos G.P., Loriaux D.L., Mann D., Cutler G.B. Jr. (1982) Late-onset 21-hydroxylase deficiency is an allelic variant of congenital adrenal hyperplasia characterized by attenuated clinical expression and different HLA haplotypes associates. Horm. Res. 16: 193-200. 9. Chrousos G.P., Brown T., Bercu B. (1982) Pharmacologic Effects of Melatonin on Hypothalamic- Adenohypophyseal Function in the Nonhuman Primate. Neuroendocrinology 34: 343-346. 10. Chrousos G.P., Renquist D., Brandon D., Barnard D., Fowler D., Loriaux D.L., Lipsett M.B. (1982) The Squirrel Monkey: Receptor-mediated End-organ Resistance to Progesterone? J. Clin. Endocrinol. Metab. 55: 364-368. 11. Chrousos G.P., Renquist D., Brandon D., Eil C., Pugeat M., Vigersky R., Cutler G.B., Loriaux D.L., Lipsett M.B. (1982) Glucocorticoid Resistance and Primate Evolution: Receptor-mediated Mechanisms. Proc. Natl. Acad. Sci. 179: 2036-2040. 12. Chrousos G.P., Loriaux D.L., Mann D.L., Cutler G.B. Jr. (1982) Late-onset 21-Hydroxylase Deficiency Mimicking Polycystic Ovarian Disease: An Allelic Variant of Congenital Virilizing Adrenal Hyperplasia with a Milder Enzymatic Defect. Ann. In. Med. 96: 143-148. 13. Chrousos G.P., Poplack D., Brown T., O'Neil D., Schwade J., Bercu B. (1982) Effects of Cranial Radiation on Hypothalamic-Anterior Pituitary Function: Abnormal Growth Hormone Secretory Dynamics. J. Clin. Endocrinol. Metab. 54: 1135-1139. 14. Chrousos G.P., Vingerhoeds A., Brandon D., Pugeat M., Eil C., Loriaux D.L., Lipsett M.B. (1982) Primary Cortisol Resistance in Man: A Glucocorticoid Receptor-mediated Disease. J. Clin. Invest. 69: 1261-1269. 15. Cassorla F., Albertson B., Chrousos G.P., Booth J., Renquist D., Lipsett M.B., Loriaux D.L. (1982) The Mechanism of Hypercortisolemia in the Squirrel Monkey. Endocrinology 111: 448-451. 16. Schulte H.M., Chrousos G.P., Oldfield R., Gold P., Cutler G.B. Jr., Loriaux D.L. (1982) The effects of 9
  10. 10. George P. Chrousos, M.D. Corticotropin Releasing Factor on the Anterior Pituitary Function of Stalk-Sectioned Cynomolgus Macaques. Dose Response of Cortisol Secretion. J. Clin. Endocrinol. Metab. 55: 810-812. 17. Schulte H.M., Chrousos G.P., Gold P., Philips J., Cutler G.B. Jr., Loriaux D.L. (1982) Metabolic Clearance Rate and Plasma Half-life of Radioiodinated Corticotropin Releasing Factor in a Nonhuman Primate. J. Clin. Endocrinol. Metab. 55: 1023-1025. 18. Chrousos G.P., Sauer M.A., Cutler G.B. Jr., Loriaux D.L. (1982) 1-11-Oxa-11-deoxycortisol: A New Antiglucocorticoid with Activity in vivo. Steroids 40: 425-431. 19. Healy D.L., Hodgen G.D., Schulte H.M., Chrousos G.P., Loriaux D.L., Nicholas R.H., Goldstein H.L. (1983) The Thymus-adrenal Connection: Thymosin Has Corticotropin Releasing Activity in Primates. Science 222: 1353-1355. 20. Chrousos G.P., Vingerhoeds A.C.M., Loriaux D.L., Lipsett M.B. (1983) Primary Cortisol Resistance: A Family Study. J. Clin. Endocrinol. Metab. 56: 1243-1245. 21. Healy D.L., Chrousos G.P., Schulte H.M., Williams R.F., Baulieu E.E., Gold P.W., Hodgen G.D. (1983) Pituitary and Adrenal Responses to the Anti-progesterone and Antiglucocorticoid Steroid RU 486 in Primates. J. Clin. Endocrinol. Metab. 57: 863-865. 22. Jacobowitz D.M., Schulte H.M., Chrousos G.P., Loriaux D.L. (1983) Localization of GRF-like Immunoreactive Neurons in the Rat Brain. Peptides 4: 521-524. 23. Pugeat M., Rocle B., Chrousos G.P., Dunn J., Lipsett M.B., Nisula B.C. (1984) Plasma Testosterone Transport and Primate Evolution. J. Steroid Biochem. 20: 473-478. 24. Schulte H.M., Chrousos G.P., Gold P.W., Oldfield E.H., Cutler G.B. Jr., Loriaux D.L. (1984) Corticotropin Releasing Factor: Pharmacokinetics in Man. J. Clin. Endocrinol. Metab. 58: 192-196. 25. Doppman J.L., Oldfield E.H., Krudy A.G., Chrousos G.P., Schulte H.M., Loriaux D.L., Schaaf M. (1984) Anatomic and Technical Considerations of the Inferior Petrosal Sinus Sampling for Cushing's Disease. Radiology. 150: 999-103. 26. Almeida O.F.X., Schulte H.M., Rittmaster R.S., Chrousos G.P., Loriaux D.L., Merriam G.R. (1984) Potency and Specificity of a Growth Releasing Factor in a Primate and in Vitro. J. Clin. Endocrinol. Metab. 58: 309-312. 27. Chrousos G.P., Brandon D., Tomita M., Renquist D., Hogan W., Loriaux D.L., Lipsett M.B. (1984) Estrogen and Progesterone Receptors in a Progesterone "Resistant" New World Primate. J. Clin. Endocrinol. Metab. 58: 516-520. 28. Chrousos G.P., Schulte H.M., Oldfield E.H., Gold P.W., Cutler G.B. Jr., Loriaux D.L. (1984) The Corticotropin Releasing Factor Stimulation Test: An Aid in the Differential Diagnosis of Cushing's Syndrome. N. Engl. J. Med. 310: 622-627. 29. Schulte H.M., Chrousos G.P., Avgerinos P., Gold P.W., Oldfield E.H., Cutler G.B. Jr., Loriaux D.L. (1984) The Corticotropin Releasing Factor Stimulation Test: a Possible Aid in the Evaluation of Adrenal Insufficiency. J. Clin. Endocrinol. Metab. 58: 1064-1067. 30. Chrousos G.P., Loriaux D.L., Brandon D., Hogan W., Renquist D., Johnson E., Lipsett M.B. (1984) Adaptation of the Mineralocorticoid Target Tissues to the High Circulation Cortisol and Progesterone Plasma Levels in the Squirrel Monkey. Endocrinology 115: 25-32. 10
  11. 11. George P. Chrousos, M.D. 31. Pugeat M., Chrousos G.P., Nisula B., Loriaux D.L., Brandon D.D., Lipsett M.B. (1984) Plasma Cortisol Transport and Primate Evolution. Endocrinology 115: 357-361. 32. Rock J., Oldfield E.H., Schulte H.M., Gold P.W., Kornblith P.L., Loriaux D.L., Chrousos G.P., (1984) Corticotropin Releasing Factor Administered into the Ventricular CSF Stimulates the Pituitary-adrenal Axis. Brain Res. 323: 376-368. 33. Crawley J.N., Ninan P.T., Pickar D., Chrousos G.P., Linnoila M., Scolnick, Paul S.M. (1984) Neuropharmacological Antagonism of the beta-Carboline-induced "Anxiety" Response in Rhesus Monkeys. J. Neuroscience 5: 477-485. 34. Winterer J., Chrousos G.P., Cassorla F., Loriaux D.L. (1984) Acquired Refractoriness to Growth Hormone in a Patient with Isolated Growth Hormone Deficiency: Growth Hormone and Plasma Somatomedin C Response to High Dose Growth Hormone Therapy. J. Pediatrics, 104: 908-911. 35. Schuermeyer T.H., Avgerinos P.C., Gold P.W., Cutler G.B. Jr., Loriaux D.L., Chrousos G.P. (1984) Human Corticotropin Releasing Factor in Man. Pharmacokinetic Properties and Dose-response of Plasma ACTH and Cortisol Secretion. J. Clin. Endocrinol. Metab. 59: 1103-1108. 36. Udelsman R., Bacher J., Galluci W., Gold P.W., Morin M.L., Renquist D., Loriaux D.L., Chrousos G.P. (1984) Hemodynamic and Endocrine Parameters in the Anesthetized Cynomolgus Monkey: A Primate Model. J. Med. Primatol. 13: 327-337. 37. Chrousos Antonakou G., Levine Ross J., Chrousos G.P., Chu F.C., Kenigsberg D., Cutler G.B. Jr., Loriaux D.L. (1984) Ocular Findings in Turner Syndrome. A Prospective Study. Ophthalmology 91: 926-928. 38. Tomita M., Chrousos G.P., Brandon D.D., Ben-Or S., Foster C., DeVougn L., Taylor S.J., Loriaux D.L., Lipsett M.B. (1985) Glucocorticoid Receptors in Epstein-Barr Virus-transformed Human Lymphocytes. Hormone Metabol. Res. 17: 674-678. 39. Oldfield E.H., Chrousos G.P., Schulte H.M., Rock J.P., Poplack D.G., Gold P.W., Culter G.B. Jr., Kornblith P.L., Loriaux D.L. (1985) Active Clearance of Corticotropin-Releasing Factor from the Cerebrospinal Fluid. Neuroendocrinology 40: 84-87. 40. Evans M.I., Chrousos G.P., Mann D.L., Larsen J.W., McCluskey J., Green I., Loriaux D.L., Overpeck J., Fletcher J., Schulman J. (1985) Attempted Prevention of Abnormal Genital Masculinization in Suspected Congenital Adrenal Hyperplasia by Adrenocortical Suppression in Utero. JAMA 253:1015- 1020. 41. Schulte H.M., Chrousos G.P., Oldfield E.H., Gold P.W., Cutler G.B. Jr., Loriaux D.L. (1985) Corticotropin Releasing Factor Administration in Normal Men: Pituitary and Adrenal Responses in the Morning and Evening. Horm. Res. 21: 69-74. 42. Winterer J., Chrousos G.P., Loriaux D.L., Cutler G.B. Jr. (1985) The Adrenal Suppressive Effect of Hydrocortisone in Congenital Adrenal Hyperplasia is not Affected by Varying the Dose Schedule. J. Pediatrics 106: 137-142. 43. Schuermeyer T.H., Gold P.W., Galluci W.T., Tomai T.P., Cutler G.B. Jr., Loriaux D.L., Chrousos G.P. (1985) Effects and Pharmacokinetic Properties of the rat/human Corticotropin Releasing Factor (r/h CRF) in Rhesus Monkeys. Endocrinology 117: 300-306. 44. Schutt-Aine J., Young M.A., Pescovitz O.H., Chrousos G.P., Marx S.J. (1985) Hypoparathyroidism: a Possible Cause of Rickets. J. Pediatrics. 106: 255-259. 45. Healy D.L., Chrousos G.P., Schulte H.M., Gold P.W., Hodgen G.D. (1985) Increased ACTH, Cortisol and 11
  12. 12. George P. Chrousos, M.D. Arginine Vasopressin (AVP) Secretion Following the Antiglucocorticoid RU 486: Dose-response Relationships. J. Clin. Endocrinol. Metab. 60: 1-4. 46. Oldfield E.H., Chrousos G.P., Schulte H.M., Loriaux D.L., Schaaf M., Doppman J. (1985) Preoperative Lateralization of ACTH Secreting Pituitary Microadenomas by Bilateral and Simultaneous Inferior Petrosal Sinus Sampling: N. Engl. J. Med. 312: 100-103. 47. Rittmaster R.S., Cutler G.B. Jr., Sobel D.O., Koppelman M.C.S., Loriaux D.L., Chrousos G.P. (1985) Morphine Inhibits the Pituitary-adrenal Response to Ovine Corticotropin Releasing Factor in Normal Subjects. J.Clin. Endocrinol Metab 60: 891-895. 48. Schuermeyer T.H., Tsokos G.C., Avgerinos P.C., Loriaux D.L., Balow J.E., Chrousos G.P. (1985) Pituitary-adrenal Responsiveness to Corticotropin-releasing Hormone in Patients Receiving Chronic, Alternate-day Glucocorticoid Therapy. J. Clin. Endocrinol. Metab. 61: 22-27. 49. Schulte H.M., Chrousos G.P., Gold P.W., Booth J.D., Oldfield E.H., Culter G.B. Jr., Loriaux D.L. (1985) Continuous Administration of Corticotropin Releasing Hormone in Normal Volunteers: Physiological and Pathophysiological Implications. J. Clin. Invest. 75: 1781-1785. 50. Susman E., Nottelman F., Inoff G., Dorn L., Loriaux D.L. Cutler G.B. Jr., Chrousos G.P. (1985) The Relation of Hormonal Level and Physical Development and Social-emotional Behavior in Young Adolescents. J. Youth and Adolescence. 14: 245-264. 51. Rose S., Schulte H.M., Rauch A., White B., Hill S., Chandra R., Randolf J., Loriaux D.L., Chrousos G.P. (1985) Testicular Dysgenesis and Mixed Gonadal Dysgenesis: Biochemical Characterization and Management of a Typical Case. J. Ped. Endocrinol. 1: 123-128. 52. Berrettini H.W., Nurnberger J., Gold P.W., Chretien M., Chrousos G.P., Chan J.S.D., Goldin L.R., Gerson E. (1985) Neuropeptides in the Human Cerebrospinal Fluid. Life Sciences 37: 1265-1270. 53. Udelsman R., Harwood J., Millan M., Chrousos G.P., Catt K.J., Aguilera G. (1985) Functional Receptors for Corticotropin Releasing Factor in the Primate Peripheral Sympathetic System. Nature 319: 147-150. 54. Berrettini W.H., Nurnberger J.I., Chan J.S., Chrousos G.P., Gaspar L., Gold P.W., Seidah N.G., Simmons- Alling S., Goldin L.R., Chretien M., Gershon E.S. (1985) Proopiomelanocortin-related Peptides in Cerebrospinal Fluid: A Study of Manic Depressive Disorder. Psychiatry Res. 16: 287-302. 55. Nieman L.K., Chrousos G.P., Kellner C., Spitz I., Nisula B., Cutler G.B. Jr., Merriam G.R., Bardin C.W., Loriaux D.L. (1985) Successful Treatment of Cushing's Syndrome with the Glucocorticoid Antagonist RU 486. J. Clin. Endocrinol. Metab. 61: 536-540. 56. Gold P.W., Loriaux D.L., Roy A., Kling M.A., Calabrese J.R., Kellner C.H., Nieman L.K., Post R.M., Pickar D., Gallucci W., Avgerinos P., Paul S., Oldfield E.H., Cutler G.B. Jr., Chrousos G.P. (1986) Responses to Corticotropin Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease: Pathophysiologic and Diagnostic Implications. N. Engl. J. Med. 314: 1329-35. 57. Rose S.R., Chrousos G.P., Cornblath M., Sidbury J. (1986) Oral Starch in the Management of Post- operative Nesidioblastosis. J. Pediatrics 108: 97-100. 58. Tomita M., Brandon D., Chrousos G.P., Vingerhoeds A.C.M., Foster C.M., Loriaux D.L., Lipsett M.B. (1986) Characterization of Glucocorticoid Receptors from Epstein-Barr Virus-transformed Lymphocytes from Glucocorticoid Resistant Patients and a New World Primate. J. Clin. Endocrinol. Metab. 62: 1145- 1154. 12
  13. 13. George P. Chrousos, M.D. 59. Weiss S.R.B., Post R.M., Gold P.W., Chrousos G.P., Sullivan T.L., Walker D., Pert A. (1986) CRF- induced Seizures and Behavior: Interaction with Amygdala Kindling. Brain Res. 372: 345-351. 60. Levine Ross J., Schulte H.M., Gallucci W.T., Cutler G.B. Jr., Loriaux D.L., Chrousos G.P. (1986) Ovine Corticotropin Releasing Hormone Stimulation Test in Normal Children. J. Clin. Endocrinol. Metab. 62: 390-392. 61. Schiebinger R., Chrousos G.P., Cutler G.B., Loriaux D.L. (1986) The Effect of Serum Prolactin on Plasma Adrenal Androgens and the Production and Metabolic Clearance Rate of Dehydroepiandrosterone Sulfate in Normal and Hyperprolactinemic Subjects. J. Clin. Endocrinol. Metab. 62: 202-209. 62. Gold P.W., Gwirtzman H., Avgerinos P., Nieman L.K., Gallucci W.T., Kaye W., Jimerson D., Ebert M., Rittmaster R., Loriaux D.L., Chrousos G.P. (1986) Abnormal Hypothalamic-pituitary-Adrenal Function in Anorexia Nervosa: Pathophysiologic Mechanisms in Underweight and Weight-corrected Patients. N. Engl. J. Med. 314: 1335-42. 63. Avgerinos P.C., Schuermeyer T., Gold P.W., Loriaux D.L., Cutler G.B. Jr., Chrousos G.P. (1986) Pulsatile Administration of Human Corticotropin Releasing Hormone in Patients with Secondary Adrenal Insufficiency: Restoration of the Normal Cortisol Secretory Pattern. J. Clin. Endocrinol. Metab. 62: 816- 821. 64. Rosner W., Pugeat M., Chrousos G.P., Khan M.S. (1986) Steroid Binding Proteins in Primate Plasma. Endocrinology. 118: 513-517. 65. Pavlov E.P., Harman M.S., Chrousos G.P., Loriaux D.L., Blackman M.R. (1986) Responses of Plasma Adrenocorticotropin (ACTH), Cortisol, and Dehydroepiandrosterone to Ovine Corticotropin Releasing Hormone in Healthy Aging Men. J. Clin. Endocrinol. Metab. 62: 767-772. 66. Oldfield E.H., Schulte H.M., Chrousos G.P., Gold P.W., Benker G., Peterson R.E., Cutler G.B. Jr., Loriaux D.L. (1986) Corticotropin Releasing Factor Stimulates ACTH Secretion in Nelson's Syndrome. J. Clin. Endocrinol. Metab. 62: 1020-1026. 67. Udelsman R., Gallucci W.T., Ramp J., Goldstein D.S., Lipford R., Norton J.A., Loriaux D.L., Chrousos G.P. (1986) Adaptation during Surgical Stress: A Reevaluation of the Role of Glucocorticoids. J. Clin. Invest. 77: 1377-1381. 68. Roy-Byrne P.P., Uhde T.W., Post R.M., Gallucci W., Chrousos G.P., Gold P.W. (1986) The CRH Stimulation Test in Patients with Panic Disorder. Am. J. Psychiatry, 143: 396-399. 69. Roy A., Gold P.W., Pickar D., Wolkowitz O.M., Chrousos G.P., Paul S.M. (1986) Pre- and Post- dexamethasone Plasma ACTH Levels in Depressed Patients and Normal Controls. J. Affective Dis. 10: 95- 99. 70. Udelsman R., Bacher J., Gallucci P.W., Gold P.W., Renquist D., Loriaux D.L., Chrousos G.P. (1986) Hemodynamic Effects of Human Corticotropin-releasing Factor (hCRF) in a Nonhuman Primate. Peptides 7: 465-471. 71. Munabi A., Feuillan P., Staton R., Rodbard D., Chrousos G.P., Anderson R.E., Strober M.D., Loriaux D.L., Cutler G.B. Jr. (1986) Adrenal Steroid Responses to Continuous Intravenous ACTH Infusion Compared to Bolus Injection. J. Clin. Endocrinol. Metab. 63: 1036-1040. 72. Nieman L.K., Chrousos G.P., Oldfield E.H., Avgerinos P.C., Cutler G.B. Jr., Loriaux D.L. (1986) The Ovine CRH Stimulation Test and the Dexamethasone Suppression Test in the Differential Diagnosis of Cushing's Syndrome. Ann. Int. Med. 105: 862-867. 13
  14. 14. George P. Chrousos, M.D. 73. A., Pickar D., Doran A., Wolkowitz O., Gallucci W., Chrousos G.P., Gold P.W. (1986) Normal ACTH and cortisol Responses to Corticotropin Releasing Hormone in Schizophrenia. Am. J. Psychiatry 143: 1393-1397. 74. Saris S.C., Patronas N.J., Doppman J.L., Loriaux D.L., Cutler G.B. Jr., Nieman L.K., Chrousos G.P., Oldfield E. (1986) Pituitary CT Scanning in Cushing's Syndrome. Radiology 162: 775-777. 75. Doppman J.L., Oldfield E.H., Chrousos G.P., Nieman L.K., Udelsman R., Cutler G.B. Jr., Loriaux D.L. (1986) Rebound Thymic Hyperplasia Following Treatment of Cushing's Syndrome. Am. J. Radiology 147: 1145-1147. 76. Feuillan P., Poth M., Reilly W., Bright G., Loriaux D.L., Chrousos G.P. (1986) Ketokonazole Treatment of Type Autoimmune Polyglandular Syndrome: Effects on Pituitary-adrenal Axis. J. Pediatrics, 109: 363- 366. 77. Nottelman E.D., Susman E.J., Dorn L.D., Inoff G.E., Loriaux D.L., Cutler G.B., Chrousos G.P. (1987) Developmental Processes in Early Adolescence: Relations among Chronological Age, Pubertal Stage, Height, Weight, and Serum Levels of Gonadotropins, Sex Steroids and Adrenal Androgens. J. Adol. Health Care 8: 35-48. 78. Susman E., Inoff G., Nottelman E., Dorn L., Loriaux D.L., Chrousos G.P. (1987) Hormones, Emotional Disposition and Aggression Attributes in Early Adolescents. Child Development 58: 1114-1134. 79. Rittmaster R.S., Cutler G.B. Jr., Brandon D., Gold P.W., Loriaux D.L., Chrousos G.P. (1987) The Effects of Endogenous Vasopressin on ACTH and Cortisol Secretion in Man. J. Clin. Endocrinol. Metab. 64: 371- 376. 80. Laue L., Hoeg J.M., Barnes K., Loriaux D.L., Chrousos G.P. (1987) The Effect of Mevinolin on Steroidogenesis in Patients with Defects in the LDL Receptor Pathway. J. Clin. Endocrinol. Metab. 64: 531-535. 81. Kaye W.H., Gwirtsman H.E., George D.T., Ebert M., Jimerson D., Tomai T., Chrousos G.P., Gold P.W. (1987) Elevated Cerebro-spinal Fluid Levels of Immunoreactive Corticotropin Releasing Hormone in Anorexia Nervosa: Relation to State of Nutrition, Adrenal Function and Intensity of Depression. J. Clin. Endocrinol. Metab. 64: 203-208. 82. Nieman L.K., Choate T., Chrousos G.P., Healy D., Spitz I., Merriam G.R., Bardin C.W., Loriaux D.L. (1987) Progesterone Antagonist RU 486: A Potential New Contraceptive Agent. N. Engl. J. Med. 316: 187-191. 83. Nottelman E.D., Susman E.J., Dorn L.D., Inoff E.G., Loriaux D.L., Cutler G.B., Chrousos G.P. (1987) Developmental Processes in American Early Adolescents: Relations Between Adolescent Adjustment and Chronological Age, Pubertal Stage and Puberty-related Hormone Levels. J. Pediatrics 110: 473-480. 84. Udelsman R., Norton J., Jelenich S., Goldstein D., Linehan W.M., Loriaux D.L., Chrousos G.P. (1987) Responses of the Hypothalamic-pituitary-adrenal and Renin-angiotensin Axis and the sympathetic System during Controlled Surgical and Anesthesia Stress. J. Clin. Endocrinol. Metab. 64: 986-994. 85. Feuillan P., Stein C.A., LaRocca R., Lipford N., Raffeld M., Renquist D., Meyers C.E., Chrousos G.P. (1987) Effects of Suramin on the Function and Structure of the Adrenal Cortex in the Cynomolgus Monkey. J. Clin. Endocrinol. Metab. 65: 153-158. 86. Kawai S., Nieman L.K., Brandon D.D., Udelsman R., Loriaux D.L., Chrousos G.P. (1987) 14
  15. 15. George P. Chrousos, M.D. Pharmacokinetic Properties of the Antiglucocorticoid and Antiprogesterone Steroid of RU 486 in Man. J. Exp. Pharmacol. Ther. 241: 401-406. 87. Luger A., Deuster P., Kyle S.B., Gallucci W.T., Montgomery L.C., Gold P.W., Loriaux D.L., Chrousos G.P. (1987) Acute Hypothalamic-pituitary-adrenal Responses to the Stress of Treadmill Exercise: Physiologic Adaptations to Physical Training. N. Engl. J. Med. 316: 1309-1315. 88. Doppman J.L., Loughlin T., Miller D.L., Pass V.J., Chrousos G.P., Cutler G.B. Jr., Oldfield E.H., Loriaux D.L. (1987) Identification of ACTH Producing Intrathoracic Tumors by Measuring ACTH Levels on Aspirated Specimens. Radiology 163: 501-503. 89. Risin Counts D., Hirsch Pescovitz O., Barnes K.M., Chrousos G.P., Sherins R.J., Comite F., Loriaux D.L., Cutler G.B. (1987) Dissociation of Adrenarche and Gonadarche in Precocious Puberty and in Hypogonadotropic Hypogonadism J. Clin. Endocrinol. Metab. 64: 1174-1178. 90. Udelsman R., Goldstein D., Loriaux D.L., Chrousos G.P. (1987) Catecholamine-glucocorticoid Interactions during Surgical Stress. J. Sur. Res. 43: 539-545. 91. May C., Rapoport S.J., Cutler N.R., Chrousos G.P., Tomai T.P., Gold P.W. (1987) CSF Concentrations of Corticotropin Releasing Hormone and Corticotropin Are Reduced in Patients with Alzheimer's Disease. Neurology 37: 535-538. 92. Roy A., Pickar D., Linnoila M., Chrousos G.P., Gold P.W. (1987) Cerebrospinal Fluid Corticotropin Releasing Hormone in Depression: Relationship to Noradrenergic Function. Psychiatry Res. 20: 229-237. 93. Avgerinos P.C., Cutler G.B. Jr., Tsokos G.C., Gold P.W., Feuillan P., Gallucci W.T., Pillemer S.R., Loriaux D.L., Chrousos G.P. (1987) Dissociation between Cortisol and Adrenal Androgen Secretion in Patients Receiving Alternate Day Prednisone Therapy. J. Clin. Endocrinol. Metab. 65: 24-29. 94. Roy A., Pickar D., Paul S., Doran A., Chrousos G.P., Gold P.W (1987) CSF Corticotropin Releasing Hormone in Depressed Patients and Normal Control Subjects. Am. J. Psychiatry 114: 641-645. 95. Luger A., Calogero A., Kalogeras K., Gallucci W., Gold P.W., Loriaux D.L., Chrousos G.P. (1987) Interaction of Epidermal Growth Factor with the Hypothalamic-pituitary Adrenal Axis: Potential Physiologic Relevance. J. Clin. Endocrinol. Metab. 66: 334-337. 96. Laue L., Chrousos G.P., Loriaux D.L., Nieman L.K., Munson P., Schaison G. (1987) RU 486 Suppresses the Plasma ACTH Response to Ovine Corticotropin-releasing Hormone. J. Clin. Endocrinol. Metab. 66: 290-293. 97. Grino M., Chrousos G.P., Margioris A. (1987) The Corticotropin Releasing Factor Gene is Expressed in the Human Term Placenta. Biol. Bioph. Res. Com 148: 1208-1214. 98. Doppman J.L., Miller D.L., Dwyer A.J., Loughlin T., Nieman L., Cutler G.B., Chrousos G.P., Oldfield E., Loriaux D.L. (1987) Macronodular Adrenal Hyperplasia in Cushing's Disease. Radiology 166: 347-352. 99. Avgerinos P.C., Chrousos G.P., Nieman L.K., Oldfield E.H., Loriaux D.L., Cutler G.B. (1987) The Corticotropin Releasing Hormone Test in the Postoperative Evaluation of Patients with Cushing's Syndrome. J. Clin. Endocrinol. Metab. 65: 906-913. 100. Balis F.M., Lester C.M., Chrousos G.P., Heideman R.L., Poplack D.G. (1987) Differences in Cerebrospinal Fluid Penetration of Corticosteroids: Possible Relationship to Prevention of Meningeal Leukemia. J Clin Oncol 5: 202-207. 15
  16. 16. George P. Chrousos, M.D. 101. Berrettini W.H., Nurnberger J.I. Jr., Zerbe R.L., Gold P.W., Chrousos G.P., Tomai T. (1987) CSF Neuropeptides in Euthymic Bipolar Patients and Controls. Br. J. Psychiatry 150:208-212. 102. Roy A., Gallucci W., Linnoila M., Chrousos G.P., Gold P.W. (1988) The CRH Stimulation Test in Bereaved Subjects with and without Accompanying Depression. Psych. Res. 25:145-156. 103. Albertson B., Brandon D.D., Chrousos G.P., Loriaux D.L. (1988) Adrenal 11-Hydroxylase Activity in a Hypercortisolemic New World Primate: Adaptive Intra-adrenal Changes. Steroids 49: 497-505. 104. Inoff-Germain G., Snyder Arnold G., Nottelmann E.D., Susman E.J., Cutler G.B. Jr., Chrousos G.P. (1988) Relations between Hormone Levels and Observational Measures of Aggressive Behavior of Young Adolescents in Family Interactions. Dev. Psychol. 24: 129-139. 105. Laue L., Hoeg J., Barnes K., Levine Ross J., Loriaux D.L., Chrousos G.P. (1988) Abnormal Growth Hormone Secretory Dynamics in Children with Familial Hypercholesterolemia. Hormone Res. 938:1-6. 106. Calogero A.E., Bernardini R., Gallucci W.T., Saoutis C., Gold P.W., Chrousos G.P. (1988) Cholinergic Stimulation of Rat Hypothalamic Corticotropin Releasing Hormone in Vitro. Neuroendocrinology 47: 303- 308. 107. Giuffre K., Udelsman R., Listwak S., Chrousos G.P. (1988) Effects of Immune Neutralization of CRH, ACTH, and Endorphin in the Surgically Stressed Rat. Endocrinology 122: 306-310. 108. Feuillan P., Pang S., Avgerinos P., Schuermeyer T., Chrousos G.P. (1988) Adaptation of the Hypothalamic-pituitary-adrenal Axis in Patients with Partial (Late-onset) 21-Hydroxylase Deficiency. J. Clin. Endocrinol. Metab. 67: 154-160. 109. Margioris A., Grino M., Protos P., Gold P.W., Chrousos G.P. (1988) Corticotropin Releasing Hormone and Oxytocin Stimulate the Secretion of Immunoreactive alpha-MSH, beta-Endorphin and ACTH from the Human Placenta In Vitro. J. Clin. Endocrinol. Metab. 66: 922-926. 110. Laue L., Kawai S., Brandon D., Knazek R., Loriaux D.L., Chrousos G.P. (1988) Receptor-Mediated Effects of Glucocorticoids on Inflammation: Enhancement of the Inflammatory Response with a Glucocorticoid Antagonist. J. Steroid Biochem. 29: 591-598. 111. Luger A., Deuster P., Kyle S.B., Gallucci W.T., Montgomery L.C., Loriaux D.L., Chrousos G.P. (1988) Renin-angiotensin Responses during Treadmill Exercise. Hormone Res. 30: 5-9. 112. Laue, L., Gallucci, W., Loriaux, D.L., Udelsman, R., Chrousos G.P. (1988) The Antiglucocorticoid and Antiprogestin Steroid RU 486: Its Glucocorticoid Agonist Effect is Inadequate to Prevent Adrenal Insufficiency in Primates. J. Clin. Endocrinol Metab. 67: 602-606. 113. Calogero A.E., Gallucci W.T., Chrousos G.P., Gold P.W. (1988) Interaction between Gabaergic Neurotransmission and Rat Hypothalamic Corticotropin Releasing Hormone Secretion In Vitro. Brain Res. 463: 28-36. 114. Calogero A.E., Gallucci W.T., Chrousos G.P., Gold P.W. (1988) Effect of the Catecholamines Upon Rat Hypothalamic Corticotropin Releasing Hormone Secretion In Vitro: Clinical Implications. J. Clin. Invest. 82: 839-846. 115. Calogero A., Gallucci W.T., Gold P.W., Chrousos G.P. (1988) Multiple Regulatory Feedback Loops on Hypothalamic Corticotropin Releasing Hormone Secretion. J. Clin. Invest. 82: 767-774. 116. Doppman J.L., Frank J.A., Dwyer A.J., Oldfield E.H., Miller D.L., Nieman L.K., Chrousos G.P., Cutler 16
  17. 17. George P. Chrousos, M.D. G.B. Jr., Loriaux D.L. (1988) Gadolinium DPTA Enhanced MR Imaging of ACTH-Secreting Microadenomas of the Pituitary Gland. J. Comp. Assist. Tom. 12: 728-735. 117. Laue L., Peacock J., Gallucci W.T., Brandon D.D., Cutler G.B. Jr., Loriaux D.L., Chrousos G.P., Norton J.A. (1988) Glucocorticoid Receptor-mediated Effects on Rat Fibrosarcoma Growth. Cancer Res. 48: 2703-2706. 118. Deuster P., Chrousos G.P., Luger A., Kyle S.B., Gallucci W.T., Montgomery L.C., Loriaux D.L. (1989) Sympathetic System Responses to the Stress of Treadmill Exercise. Physiologic Adaptations to Physical Training. Metabolism 38: 141-148. 119. Calogero A.E., Bernardini R., Margioris A.N., Gallucci W.T., Munson P.J., Tamarkin L., Tomai T.P., Brody L., Gold P.W., Chrousos G.P. (1989) Serotonin Stimulates Rat Hypothalamic Corticotropin Releasing Hormone Secretion In Vitro. Peptides 10: 189-210. 120. Kawai S., Brandon D., Loriaux D.L., Chrousos G.P. (1989) Interaction of RU 486, A Glucocorticoid and Progesterone Antagonist, with Human Circulating Mononuclear Leukocytes. Am. J. Med. Sci. 296: 167- 171. 121. Friedman R.B., Oldfield E.H., Nieman L.K., Chrousos G.P., Doppman J.L., Cutler G.B. Jr., Loriaux D.L. (1989) Repeat Transsphenoidal Surgery in Cushing's Disease. J. Neurosurg. 71: 520-527. 122. Margioris A., Koukoulis G., Grino M., Chrousos G.P. (1989) In Vitro Perifused Rat Testis Fragments Secrete beta-Endorphin and Dynorphin: Effect of Opioids on Testosterone Secretion. Biol. Reprod. 40: 776-784. 123. Perry R.R., Nieman L.K., Cutler G.B. Jr., Chrousos G.P., Loriaux D.L., Doppman J.L., Travis W.D., Norton J.A. (1989) Primary Adrenal Causes of Cushing's Syndrome: Diagnosis and Surgical Management. Ann. Surg. 210: 59-68. 124. Sternberg E., Hill J.M., Chrousos G.P., Kamilaris T., Listwak S., Gold P.W., Wilder R.L. (1989) Inflammatory mediator-induced Hypothalamic-pituitary-adrenal Axis Activation is Defective in Streptococcal Cell Wall Arthritis - susceptible Lewis Rats. Proc. Natl. Acad. Sci. USA 86: 2374-2378. 125. Gomez M.T., Chrousos G.P. (1989) Periodic Cushing's Syndrome in a Short Boy: Usefulness of the Ovine CRH Test. J. Pediatr. 115: 270-273. 126. Linder B., Feuillan P., Chrousos G.P. (1989) Alternate-day Prednisone Therapy in Congenital Adrenal Hyperplasia: Adrenal Androgen Suppression and Normal Growth. J Clin. Endocrinol. Metab. 69:91-195. 127. Bagdy G., Calogero A., Chrousos G.P., Szemeredi K. (1989) Delayed Effects of Chronic Cortisol Treatment on Brain and Plasma Concentrations of Corticotropin (ACTH) and beta-Endorphin. Brain Res. 489: 216-222. 128. Sternberg E.M., Young W.S. Jr., Bernardini R., Calogero A., Chrousos G.P., Gold P.W., Wilder R.L. (1989) A Central Nervous Defect in the Stress Response is Associated with Susceptibility to Streptococcal Cell Wall Arthritis in Lewis Rats. Proc. Natl. Acad. Sci. 86: 4771-4775. 129. Bernardini R., Chiarenza A., Calogero A.E., Gold P.W., Chrousos G.P. (1989) Arachidonic Acid Metabolites Modulate Rat Hypothalamic Corticotropin Releasing Hormone Secretion in Vitro. Neuroendocrinology 50: 708-715 130. Bernardini R., Calogero A.E., Ehlich Y.H., Brucke T., Chrousos G.P., Gold P.W. (1989). The Alkyl- ether Phospholipid Platelet-activating Factor is a Stimulator of the Hypothalamic-pituitary-adrenal Axis in the 17
  18. 18. George P. Chrousos, M.D. Rat. Endocrinology 125: 1067-1073. 131. Calogero A., Gallucci W.T., Chrousos G.P., Gold P.W. (1989) Cocaine Stimulates Rat Hypothalamic Corticotropin Releasing Hormone Secretion in Vitro. Brain Res. 505: 7-11. 132. Doppman J.L., Pass H.I. Nieman L., Cutler G.B. Jr., Chrousos G.P., Loriaux D.L. (1989) Failure of Bronchial Lavage to Select Elevated Levels of ACTH in Patients with ACTH-Producing Bronchial Carcinoids. J. Clin. Endocrinol. Metab. 69: 1302-1304. 133. Travis W.D., Tsokos M., Doppman J.L., Nieman L., Chrousos G.P., Cutler G.B., Loriaux D.L., Norton J.A. (1989) Primary Pigmented Nodular Adrenocortical Disease: A Light and Electron Microscopic Study of Eight Cases. Am. J. Surg. Pathol. 13: 921-930. 134. Calogero A., Kamilaris T., Gomez M.T., Johnson E.O., Tartaglia E., Gold P.W., Chrousos G.P. (1989) The Muscarinic Cholinergic Agonist Arecoline Stimulates the Rat Hypothalamic-pituitary-adrenal Axis Through a Centrally-mediated Corticotropin-releasing Hormone Mechanism. Endocrinology 125: 2445- 2453. 135. Doppman J.L., Travis W.D., Nieman L.K., Miller D.L., Pass H.I., Chang R., Cutler G.B. Jr., Chrousos G.P., Norton J.A., Ziessman H.A., Oldfield E.H., Loriaux D.L.v(1989) Cushing's Syndrome Due to Primary Pigmented Nodular Adrenocortical Disease: Findings at CT and MR Imaging. Radiology 172(2):415-420. 136. Doppman J.L., Nieman L.K., Miller D.L., Pass H.I., Chung R., Cutler G., Schauf M., Chrousos G.P., Norton J.A., Zirrsman H.A., Oldfield E.H., Loriaux D.L. (1989) Ectopic Adrenocorticotropin Hormone Syndrome: Localization Studies in 28 Patients. Radiology 172: 115-124. 137. Nieman L.K., Cutler G.B. Jr., Oldfield E.O., Loriaux D.L., Chrousos G.P. (1989) The Ovine Corticotropin Releasing Hormone Stimulation Test is Superior to the Human Cortico- tropin Releasing Hormone Test for the Detection of Cushing's Disease. J. Clin. Endocrinol. Metab. 69: 165-169. 138. Marx S.J., Jones G., Weinstein R.J., Chrousos G.P., Renquist D. (1989) Vitamin D and Mineral Metalbolism in New World and Old World Primates: A Novel State with Hyperphosphatetic Osteomalacia in Aotus trivirgatus. J. Olin. Endocrinol. Metab. 69:1282-1290 139. Pass H.I., Doppman J.L., Nieman L., Stovroff M., Veto J., Norton J.A., Travis W., Chrousos G.P., Cutler G.B. Jr. (1990) Management of the Ectopic ACTH Syndrome Due to Thoracic Carcinoids. Ann Thorac- Surg 50: 52-57. 140. Calogero A., Kling M.A., Gallucci W.T., Bernardini R., Chrousos G.P. and P.W. Gold (1990) Procaine and Lidocaine Stimulate Corticotropin Releasing hormone Secretion by Explanted Rat Hypothalami through a Sodium Conductance Independent Mechanism. Horm. Metab. Res. 22: 1-4. 141. Dorn L., Susman E.J., Nottelmann E.D., Inoff-Germain G., Chrousos G.P. (1990) Perceptions of Puberty: Adolescent, Parent, and Health Care Personnel Ratings of Pubertal Stage. Develop. Psych. 26: 322-329. 142. Gazdar A.F., LaRocca R.V., Chen T.R., Triche T.J., Myers C.E., Chrousos G.P., Brennan M.R., Stein C.A., Oie H.K. (1990) Establishment and Characterization of a Human Adrenocortical Carcinoma Cell Line That Expresses Multiple Pathways of Steroid Biosynthesis. Cancer Res. 50: 5488-5496. 143. Rabin D., Johnson E., Brandon D., Liapi C., Chrousos G.P. (1990) Glucocorticoids Inhibit Estradiol- induced Uterine Growth: Possible Role of Estrogen Receptors. Biol. Reprod. 42: 74-80. 144. Calogero A.E., Kamilaris T.C., Bernardini R., Johnson E.O., Chrousos G.P., Gold P.W. (1990) Relevance 18
  19. 19. George P. Chrousos, M.D. of the "Peripheral" Benzodiazepine Receptor System to Hypothalamic pituitary-adrenal Function: Physiological and Clinical Implications. J. Pharmacol Exp. Therap. 253: 729-737. 145. Margioris A., Brockmann G., Bohler H., Grino M., Vamvakopoulos N., Chrousos G.P. (1990) Expression and Localization of Growth Hormone - Releasing Hormone mRNA in Rat Placenta: In Vitro Secretion and Regulation of Its Peptide Product. Endocrinology 126: 151-158. 146. Malozowski S., Muzzo S., Burrows R., Leiva L., Loriaux L., Chrousos G.P., Winterer J., Cassorla F. (1990) The Hypothalamic-pituitary-adrenal Axis in Infantile Malnutrition. Clin. Endocrinol. 32:461-465. 147. Calogero A.E., Bagdy G., Szemereti, Tartaglia M.E., Gold P.W., Chrousos G.P. (1990) Mechanisms of Serotonin Agonist-induced Activation of the Hypothalamic-pituitary-adrenal Axis in the Rat. Endocrinology 126: 1888-1894. 148. Margioris A.N., Brockmann G., Kalogeras K., Fjellestad-Paulsen A., Stratakis C.A., Vamvakopoulos N., Chrousos G.P. (1990) Effect of Hypertonic Saline Infusion on the Levels of Immunoreactive Dynorphin in Extracted Human Plasma. J. Clin. Endocrinol. Metab. 71: 298-304. 149. Bernardini R., Kamilaris T.C., Calogero A.E., Johnson E.O., Gold P.W., Chrousos G.P. (1990) Interactions Between Tumor Necrosis Factor-, Hypothalamic Corticotropin-Releasing Hormone and Adrenocorticotropin Secretion in the Rat. Endocrinology 126: 2876-81. 150. Calogero A., Kamilaris T., Johnson E.O., Tartaglia M., Chrousos G.P. (1990) Recovery of the Rat Hypothalamic-pituitary-adrenal Axis after Prolonged Treatment with Dexamethasone. Endocrinology 127: 1574-1579. 151. Vamvakopoulos N., Karl M., Mayol V., Margioris A., Chrousos G.P. (1990) Structural Analysis of the Regulatory Region of the Human Corticotropin Releasing Hormone Gene. FEBS Lett 267:1-5. 152. Kalogeras K.T., Calogero A.E., Kuribayashi T., Khan I., Gallucci W.T., Kling M.A., Chrousos G.P., Gold P.W. (1990) In vitro and In vivo Effects of the Triazolobenzodiazepine Alprazolam on Hypothalamic- pituitary-adrenal Function: Pharmacologic and Clinical Implications. J Clin Endocrinol Metab, 70: 1462- 1471. 153. Rabin D., Schmidt P., Campbell G., Gold P.W., Jensvold M., Rubinow D., Chrousos G.P. (1990) Hypothalamic-pituitary-adrenal Function in Patients with the Premenstrual Syndrome. J. Clin. Endocrinol. Metab. 71: 1158-1162. 154. Doherty J.M., Nieman L.K., Cutler G.B., Chrousos G.P., Norton J. (1990) Time to Recovery of the Hypothalamic Pituitary-Adrenal Axis Following Curative Resection of Adrenal Tumors in Patients with Cushing's Syndrome. Surgery 108:1085-90. 155. Hurley D., Accilli D., Stratakis C., Karl M., Vamvakopoulos N., Rorer E., Constantine K., Taylor S., Chrousos G.P. (1991) Mutation of the Glucocorticoid Receptor Gene in Familial Glucocortcoid Resistance. J Clin Invest 87:680-686. 156. Laue L., Lotze M.T., Chrousos G.P., Barnes K., Loriaux D.L., Fleisher T.A. (1990) Effects of the Glucocorticoid Antagonist RU 486 in Man: Toxicity, Immunological and Hormonal Aspects. J. Clin. Endocrinol. Metab. 71:1474-1480. 157. Gomez M.T., Malozowski S, Winterer J., Chrousos G.P. (1991) Urinary Free Cortisol Values in Normal Children and Adolescents. J. Pediatrics 118:256-258. 158. Bernardini R., Calogero A., Mauceri, Chrousos G.P. (1990) Rat Hypothalamic Corticotropin Releasing 19
  20. 20. George P. Chrousos, M.D. Hormone Secretion In Vitro is Stimulated by Interleukin-1 in an Eicosanoid-dependent Manner. Life Sciences 47:1601-7. 159. Bagdy G., Calogero A., Szemeredi K., Gomez M.T., Sved A.F., Murphy D.L., Chrousos G.P., Gold P.W. (1990) -Endorphin Responses to Different Serotonin Agonists: Involvement of Corticotropin Releasing Hormone, Vasopressin and Direct Pituitary Action. Brain Res. 537(1-2):227-32. 160. Bagdy G., Calogero A., Szemeredi K., Chrousos G.P., Gold P.W. (1990) effects of Cortisol Treatment on Brain and Adrenal Cortcotropin Releasing Hormone Content. Regulat. Peptides 31:83-92. 161. Doppman J.L., Nieman L.K., Travis W.D., Miller D.L., Cutler G.B., Chrousos G.P. Norton J.A. (1991) CT and MR Imaging of Massive Macronodular Adrenocortical Disease: A Rare Cause of Autonomous Primary Adrenal Hypercortisolism. J. Comp. Asst. Tom. 15:773-779. 162. Bagdy G., Chrousos G.P., Calogero A. (1991) Circadian Patterns of Plasma Corticotropin, - Endorphin, Corticosterone and Prolactin after Immunoneutralization of Corticotropin-releasing Hormone. Neuroendocrinology 53:573-578. 163. Vanderpool J., Rosenthal N., Chrousos G.P., Wehr T., Skewerer R., Kasper S., Gold P.W. (1991) Evidence for Hypothalamic CRH Deficiency in Patients with Seasonal Affective Disorder. J. Clin. Endocrinol. Metab. 72:1382-1387. 164. Doppman J., Pass H., Nieman L.K., Findling J., Dwyer A., Feuerstein I., Ling A., Travis W., Cutler G.B., Chrousos G.P., Loriaux D.L. (1991) Magnetic Resonance Imaging for Detection of ACTH- producing Bronchial Carcinoid Tumors, Am. J. Roentgen. 156:39-43. 165. Johnson E.O., Kamilaris T.C., Carter S., Gold P.W., Chrousos G.P.. (1991) Environmental Stress and Reproductive Success in the Common Marmoset (Callithrix jacchus jacchus) Am. J. Primatol 25:191- 201 (1991). 166. Kling M.A., Doran A., Rubinow D.R., Roy A., Post R.M., Chrousos G.P., Gold P.W. (1991) CSF Levels of CRH, ACTH, and SRIF in Cushing's Syndrome, Major Depression, and Normal Volunteers: Physiological and Pathophysiological Interrelationships. J. Clin. Endocrinol. Metab. 72:260-271. 167. Laue L., Peck G., Gallucci W.T., Loriaux D.L., Chrousos G.P. (1991) Adrenal Androgen Secretion in Postadolescent Cystic Acne: Increased Adrenocortical Function without Hypersensitivity to ACTH. J. Clin. Endocrinol. Metab. 73:380-384. 168. Calogero A.E., Liapi C., Chrousos G.P. (1991) Hypothalamic and Suprahypothalamic Effects of Prolonged treatment with the Glucocorticoid Type II Receptor Agonist Dexamethasone in the Rat. J. Endocrinol. Invest. 14:277-286. 169. Smoak B., Deuster P., Rabin D., Chrousos G.P. (1991) Corticotropin-Releasing Hormone is Not the Sole Factor Mediating Exercise-induced ACTH Release in Humans. J. Clin. Endocrinol. Metab. 72:302-306. 170. Sombolos K., Kapetanos G., Kalogeras K.T., Christodoulou A., Chrousos G.P., Symeonidis P. (1991) Effect on Atrial Natriuretic Peptide by Bracing in Scoliosis. Boston Brace Removal Studied in 10 cases. Acta Orthop Scand. 62:379-82. 171. Waltman C., Blackman M.R., Chrousos G.P., Riemann C., Harman S.M. (1991) Spontaneous and Glucocorticoid-inhibited Adrenocorticotropic Hormone and Cortisol Secretion Are Similar in Healthy Young and Old Men. J. Clin. Endocrinol. Metab. 73:495-502. 172. Perini G.I., Dervinsky O., Hauser P., Gallucci W.T., Theodore W., Chrousos G.P., Gold P.W., Kling M.A. 20
  21. 21. George P. Chrousos, M.D. (1992) Effects of Carbamazepine on Pituitary-adrenal Function in Healthy Volunteers. J. Clin. Endocrinol. Metab. 74:406-412. 173. Travis W.D., Linnoila R., Tsokos M., Hitchcock C., Cutler G., Nieman L., Chrousos G.P., Pass H., Doppman J. (1991) Neuroendocrine Tumors of the Lung with Proposed Criteria for Large Cell Neuroendocrine Carcinoma: An Ultrastructural, Immunochemical, and Flow Cytometric Study of 35 Cases. Amer. J. Surg. Path. 15:529-553. 174. Demitrack M., Dale J., Straus S., Laue L., Listwak S., Kruesi M., Chrousos G.P., Gold P.W. (1991) Evidence of Impaired Activation of the Hypothalamic-pituitary-adrenal Axis in Patients with Chronic Fatigue Syndrome. J. Clin. Endocrinol. Metab. 73:1224-1234. 175. Karalis C., Sano H., Redwine J., Listwak S., Wilder R., Chrousos G.P. (1991) Autocrine or Paracrine Inflammatory Actions of Corticotropin Releasing Hormone In Vivo. Science 254:421-423. 176. Friedman T.C., Thomas P.M., Fleisher T.A., Feuillan P., Parker R.I., Cassorla F., Chrousos G.P. (1991) Frequent Occurrence of Asplenism and Cholelithiasis in Patients with Autoimmune Polyglandular Disease Type I. Amer. J. Med. 91:625-630. 177. Oldfield E.H., Doppman J., Nieman L.K., Chrousos G.P., Miller D.L., Katz D.A., Cutler G.B., Loriaux D.L. (1991) Petrosal Sinus Sampling with and without Corticotropin Releasing Hormone in Patients with Cushing's Syndrome. N. Engl. J. Med. 325:897-905. 178. Susman E.J., Dorn L.D., Chrousos G.P. (1991) Negative Affect and Hormone Levels in Young Adolescents: Concurrent and Predictive Perspectives. J. Youth Adolesc. 20:167-190. 179. Calogero A., Sternberg E., Bagdy G., Smith G., Bernardini R., Aksentijevich S., Wilder R.L., Gold P.W., Chrousos G.P. (1992) Neurotransmitter-induced Hypothalamic-pituitary-adrenal Axis Responsiveness is Defective in Inflammatory Disease-Susceptible Lewis Rats: In vivo and In vitro Studies Suggesting Globally Defective Hypothalamic CRH Secretion. Neuroendocrinology. 55:600-608. 180. Calogero A.E., Norton J.A., Sheppard B.C., Listwak S.J., Cromack D.T., Wally R., Jensen R.T., Chrousos G.P. (1992) Pulsatile Activation of the Hypothalamic - pituitary - adrenal Axis during Major Surgery. Metabolism 41:839-845. 181. Aksentijevich S., Whitfield Jr H.J., Young III W.S., Wilder R.L., Chrousos G.P., Gold P.W., Sternberg E.M. (1992) Arthritis-susceptible Lewis Rats Fail to Emerge from the Stress Non-responsive period. Dev. Brain Res. 65:115-118. 182. Flack M.R., Oldfield E.H., Cutler G.B., Zweig M.H., Melley J.D., Chrousos G.P., Loriaux D.L., Nieman L.K. (1992) The Use of Urine Free Cortisol in the High Dose Dexamethasome Suppression Test for the Differential Diagnosis of Cushing's Syndrome. Ann. Int. Med. 116:211-217. 183. Kamilaris T., Johnson E., Calogero A.E., Kalogeras K., Bernardini R., Chrousos G.P., Gold P.W. (1992) Cholecystokinin-octapeptide Stimulates Hypothalamic-pituitary-adrenal Function in Rats: Role of Corticotropin-releasing Hormone. Endocrinology 130:1764-1784. 184. Calogero A.E., Kamilaris T.C., Johnson E.O., P.W., Chrousos G.P., (1992) "Peripheral" Benzodiazepine receptor Ligands Stimulate Prolactin Release in the Rat. J. Neuroendocrinology 2:745-750. 185. Luger A., Watschinger B., Deuster P., Svoboda T., Clodi M., Chrousos G.P. (1992) Plasma Growth Hormone and Prolactin Responses to Graded Levels of Acute Exercise and to a Lactate Infusion. Neuroendocrinology 56:112-117. 21
  22. 22. George P. Chrousos, M.D. 186. Marini J.C., Bordenick S., Heavner G., Rose S., Hintz R., Rosenfeld R., Chrousos G.P. (1993). The Growth Hormone and Somatomedin Axis In Short Children with Osteogenesis Imperfecta. J. Clin. Endocrinol. Metab. 76:251-256. 187. Vamvakopoulos N., Mayol V., Margioris N., Chrousos G.P. (1992) Lack of Dexamethasone Modulation of mRNAs involved in the Glucocorticoid Signal Transduction Pathway in Two Cell Systems. Steroids 57:1-6. 188. Cash J.M., Crofford L.J., Gallucci W.T., Sternberg E.M., Gold P.W., Chrousos G.P. and Wilder R.L. (1992) Pituitary-adrenal Axis Responsiveness to Ovine CRH in Patients with Rheumatoid Arthritis Treated with Low-dose Prednisone. J. Rheumatol. 19:1692-6. 189. Deuster P.A., Singh A., Hofmann A., Moses F.M., Chrousos G.P.. (1992) Hormonal Responses to Ingesting Water or a Carbohydrate Beverage During a 2h Run. Med. Sci. Sport Exerc. 24:72-79. 190. Burnet P., Meffor I.N., Smith C.C., Chrousos G.P., Gold P.W., Sternberg E.M. (1992) Hippocampal [3H]- 8-hydroxy-2,3-(diphenylalanine)-tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. J. Neurochemistry 59:1062-1070. 191. Sternberg E.M., Glowa J., Smith M.A., Calogero A.E., Listwak S.J., Aksentijevich S., Chrousos G.P., Wilder R.L., and Gold P.W. (1992) Corticotropin Releasing Hormone Related Behavioral and Neuroendocrine Responses to Stress in Lewis and Fischer Rats. Brain Res. 570:54-60. 192. Roy M.S., Roy A., Gallucci W.T., Collier B., Young K., Kamilaris T.C., Chrousos G.P. (1993) The Ovine Corticotropin Releasing Hormone Test in Type I Diabetic Patients and Controls: Suggestion of Mild Chronic Hypercortisolism. Metabolism 42:696-700. 193. Patchev V., Kalogeras K., Zelazowski P., Wilder R.L., Chrousos G.P. (1992). Increased Plasma Concentrations and Hypothalamic Content and In Vitro Release of Arginine-Vasopressin in Inflammatory Disease-prone, Hypothalamic CRH-deficient Lewis Rats. Endocrinology 131:1453-1457. 194. Kling A., Rubinow D.R., Doran A.R., Roy A., Davis C.L., Calabrese J.R., Nieman L.K., Post R.M., Chrousos G.P., Gold P.W. (1993) Cerebrospinal Fluid Immunoreactive Somatostatin Concentrations in Patients with Cushing's Disease and Major Depression: Relationship to Indices of Corticotropin-Releasing Hormone and Cortisol Secretion. Neuroendocrinology 57:79-88. 195. Chikanza I.C., Petrou P., Chrousos G.P., Kingsley G., and Panayi G. (1992) Detective Hypothalamic Response to Immune/Inflammatory Stimuli in Patients with Rheumatoid Arthritis. Arthritis and Rheumatism 35:1281-1288. 196. Karl M., Lamberts S.W., Detera-Wadleigh S., Encio I.J., Stratakis C.A., Hurley D.M., Accili D., Chrousos G.P. (1993) Familial Glucocorticoid Resistance Caused by a Splice Site Deletion in the Human Glucocorticoid Receptor Gene. J. Clin. Endocrinol. Metab. 76:683-89. 197. Crofford L.J., Sano H., Karalis K., Webster E.L., Goldmuntz E.A., Chrousos G.P., Wilder R.L. (1992) Local Secretion of Corticotropin Releasing Hormone in the Joints of Lewis Rats with Inflammatory Arthritis. J. Clin. Invest. 90:2555-2564. 198. Doppman J.L., Pass H.I., Nieman L.K., Miller D.L., Chang R., Cutler G.B., Chrousos G.P., Jaffe G.S., Norton J.A. (1992) Corticotropin-secreting Carcinoid Tumors of the Thymus: Diagnostic Unreliability of Thymic Venous Sampling. Radiology 184:71-74. 199. Cizza G., Brady L., Calogero A., Bagdy G., Lynn A.B., Kling M.A., Blackman M.R., Chrousos G. P., Gold 22
  23. 23. George P. Chrousos, M.D. P.W. (1992) Central Hypothyroidism is Associated with Advanced Age in Male Fischer 344/N Rats: In Vivo and In Vitro Studies. Endocrinology 131:2672-2680. 200. Smith C.C., Hauser E., Renaud N.K., Leff A., Aksentijevich S., Chrousos G.P., Wilder R.L., Gold P.W., Sternberg E.M. (1992) Increased Hypothalamic 3H-Flunitrazepam Binding in Hypothalamic- Pituitary- Adrenal Axis Hyporesponsive Rats. Brain Res 569:295-299. 201. Zelitch Yanovski S., Yanovski J.A., Gwirtsman H.E., Bernat A., Gold P.W., and Chrousos, G.P. (1993) Normal Dexamethasone Suppression in Obese Binge and Non-binge Eaters with Rapid Weight Loss. J. Clin. Endocrinol. Metab. 76:675-79. 202. Yanovski J.A., Cutler G.B., Chrousos, G.P., Nieman L.K. (1993) Corticotropin-releasing Hormone stimulation following low-dose dexamethasone administration: A new test to distinguish Cushings syndrome from Pseudo-Cushings states. JAMA 269:2232-38. 203. Zelazowski P., Smith M.A., Gold P.W., Chrousos G.P., Wilder R.L., Sternberg E.M. (1992) In Vitro Regulation of Pituitary ACTH Secretion in Inflammatory Disease Susceptible Lewis and Inflammatory Disease Resistant Fischer Rats. Neuroendocrinology 56:474-482. 204. Bouzas E.A., Mastorakos G., Chrousos G.P., Kaiser-Kupfer M.I. (1993) Lisch Nodules in Cushing Disease. Archives Ophthalmol. 111:439-40. 205. Swain M.G., Patchev V., Vergalla T., Chrousos G.P., Jones E.A. (1993) Suppression of Hypothalamic- pituitary-adrenal Axis Responsiveness to Stess in a Rat Model of Acute Cholestasis. J. Clin. Invest. 91:1903-1908. 206. Cizza G., Kvetnansky R., Tartaglia M.E., Blackman M.R., Chrousos G.P., Gold P.W. (1993) Immobilization Stress Rapidly Decreases Hypothalamic Corticotropin Releasing Hormone Secretion in Vitro in the male 344/N Fischer Rat. Life Sciences 53:233-240. 207. Crofford L.J., Sano H., Karalis K., Friedman T.C., Epps H.R., Remmers E.F., Mathern P., Chrousos G.P., Wilder R.L. (1993) Corticotropin-releasing Hormone in Synovial Fluids and Tissues of Patients with Rheumatoid Arthritis and Osteoarthritis. J. Immunology 151:1-10. 208. Chikanza I.C., Petrou P., Chrousos G.P., Kingsley G., Panayi G.S. (1993) Excessive and Dysregulated Secretion of Prolactin in Rheumatoid Arthritis: Immunopathogenetic and Therapeutic Implications. Br. J. Rheumatol. 32:445-448. 209. Gomez M.T., Magiakou M.A., Mastorakos G., Chrousos, G.P. (1993) The Pituitary Corticotroph is not the Rate Limiting Step in the Postoperative Recovery of the Hypothalamic-pituitary-adrenal Axis in Patients with Cushing's Syndrome. J. Clin. Endocrinol. Metab. 77:173-77. 210. Vamvakopoulos N.C., Chrousos G.P. (1993) Regulated Activity of the Distal Promoter-like Element of the Human Corticotropin-Releasing Hormone Gene and Secondary Structural Features of its Corresponding Transcripts. Mol. Cell. Endocrinol. 94:73-78. 211. Mastorakos G., Webster E.L., Friedman T.C., Chrousos G.P. (1993) Immunoreactive Corticotropin Releasing Hormone (CRH) and its Binding Sites in the Rat Ovary. J. Clin. Invest. 92:961-968. 212. Vamvakopoulos N.C., Fukuhara K., Patchev V.K., Chrousos G.P. (1993) Effect of Single and Repeated Immobilization Stress on the Heat Shock Protein (HSP) 70/90 System in the Rat: Glucocorticoid- Independent, Reversible Reduction of HSP90 in the Liver and Spleen. Neuroendocrinology 57:1057-1065. 213. Yanovski J.A., Yanovski S.Z., Gold P.W., Chrousos G.P., (1993) Differences in the Hypothalamic- 23
  24. 24. George P. Chrousos, M.D. Pituitary-Adrenal Axis of Black and White Women. J. Clin. Endocrinol. Metabol. 77:536-541. 214. Yanovski J.A., Cutler G.B., Doppman J.L., Miller D.L., Chrousos G.P., Oldfield E.H., Nieman L.K. (1993) The Limited Ability of Inferior Petrosal Sinus Sampling with Corticotropin-Releasing Hormone in Distinguishing Cushing Disease from Pseudo-Cushing States or Normal Physiology. J. Clin. Endocrinology. Metab. 77:503-509. 215. Vamvakopoulos N.C., Chrousos G.P., Griffin C.A., Hawkins A.L., Lee C., Jabs E.W. (1993) Mapping the Intron-containing Human hsp 90 (hspCAL4) Gene to Chromosome 14G32. Cytogenet Cell Gen. 64:224- 226. 216. Bouzas E.A., Scott M.H., Mastorakos S.G., Gold P.W., Chrousos G.P., Kaiser-Kupfer M.I. (1993) Central Serous Chorioretinopathy in Endogenous Hypercortisolism. Arch. Ophthalmol. 111:1229-33. 217. Vamvakopoulos N.C., Chrousos G.P. (1993) Evidence of Direct Estrogen Regulation of Human Corticotropin Releasing Hormone Gene Expression: Potential Implications for the Sexual Dimorphism of the Stress Response and Immune/Inflammatory Reaction. J. Clin. Invest. 92:1896-1902. 218. Patchev V.K., Mastorakos G., Brady L.S., Redwine J., Wilder R.L., and Chrousos G.P. (1993) Increased Arginine Vasopressin Secretion May Participate in the Enhanced Susceptibility of Lewis Rats to Inflammatory Disease. Neuroendocrinology. 58:106-110. 219. Reincke M., Karl M., Travis W., Chrousos G.P. (1993) No Evidence for Oncogenic Mutations in Guanine Nucleotide Binding Proteins of Human Adrenocortical Neoplasms. J. Clin. Endocrin. Metabol. 77:1419- 1422. 220. Tsigos C., Arai K., Hung W., Chrousos G.P. (1993) Hereditary Isolated Glucocorticoid Deficiency is Associated with Abnormalilties of the Adrenocorticotropin Receptor Gene. J. Clin. Invest. 92:2461-2485. 221. Vamvakopoulos N.C., Durkin S., Nierman W., Chrousos G.P. (1993) Mapping the Human Adrenocorticotropin Hormone (ACTHR) Gene to the Small Arm of Chromosome 18 (18p. 11.21- pter.) Genomics 18:454-455. 222. Gallucci W.T., Baum A., Laue L., Rabin D.S., Chrousos G.P., Gold P.W., Kling M.A. (1993) Sex Differences in Sensitivity of the Hypothalamic-Pituitary Adrenal Axis. Health Psychology 12:420-425. 223. Mastorakos G., Chrousos G.P., Weber J. (1993) Recombinant Interleukin 6 Activates the Hypothalamic- Pituitary-Adrenal Axis in Humans. J. Clin. Endocrinol. Metab. 27:1690-1694. 224. Reincke M., Allolio B., Petzke F., Heppner C., Mbulamberi D., Winklemann W., Chrousos G.P. (1993) Thyroid Dysfunction in African Trypanosomiasis: Evidence for Cytokine-Mediated Hypothyroidism. Clin. Endocrinol. 39:455-461. 225. Nieman L.K., Oldfield E.H., Wesley R., Chrousos G.P., Loriaux D.L., Cutler G.B. Jr., (1993) A simplified Morning Ovine Corticotropin-Releasing Hormone Stimulation Test for the Differential Diagnosis of ACTH-dependent Cushing's Syndrome. J. Clin. Endocrinol. Metab.77:1308-1312. 226. Reincke M. Allolio B., Arlt W., Heppner C., Petcke F., Mbulamberi D., Siekman L., Vollmer D., Winkleman W., Chrousos G.P. (1994) Impairment of Adrenocortical Function Associated with Increased Plasma Tumor Necrosis Factor-alpha and Interleukin-6 Concentrations in African Trypanosomiasis. NeuroImmunoModulation 1:14-22. 227. Doppman J., Nieman L.K., Cutler G.B. Jr., Chrousos G.P., Fraker D.L., Norton J.A., Jensen R.T. (1994) Adrenocorticotropin Hormone-Secreting Islet Cell Tumors: Are They Always Malignant? Radiology 24
  25. 25. George P. Chrousos, M.D. 190:59-64. 228. Zeiger M.A., Fraker D.L., Pass H.I., Nieman L.K., Cutler G.B. Jr., Chrousos G.P., Norton J.A. (1993) Effective Reversibility of the Signs and Symptoms of Hypercorticosolism by Bilateral Adrenalectomy. Surgery 114:1138-43. 229. Bouzas E.A., Mastorakos G., Friedman T.C., Scott M.H., Chrousos G.P., Kaiser-Kupfer M.I. (1993) Posterior Subcapsular Cataract in Endogenous Cushing Syndrome: An Uncommon Manifestation. Invest. Ophthalmol. Vis. Sci. 34:3497-3500. 230. Magiakou M.A., Mastorakos G., Gomez M.T., Rose S.R., Chrousos G.P. (1994) Suppressed Spontaneous and Stimulated Growth Hormone Secretion in Patients with Cushing Disease Before and After Surgical Cure. J. Clin. Endocrinol. Metab. 78:131-137. 231. Zelazowski P., Patchev V.K., Zelazowski E.B., Chrousos G.P., Gold P.W., Sternberg E.M. (1993) Release of Hypothalamic Corticotropin-Releasing Hormone and Arginine Vasopressin by Interleukin-1 and -MSH: Studies in Rats with Different Susceptibility to Inflammatory Disease. Brain Res. 631:22-26. 232. Ram Z., Nieman L.K., Cutler G.B. Jr., Chrousos G.P., Doppman J., Oldfield E.H. (1994) Early Repeat Surgery for Persistent Cushing's Disease. J. Neurosurg. 80:37-45. 233. Patchev V.K., Karalis K., Chrousos G.P. (1994) Effect of Excitatory Amino Acid Transmitters on Hypothalamic Corticotropin-Releasing Hormone (CRH) and Arginine Vasopressin Release: Implications for Pituitary-Adrenal Regulation. Brain Res. 633:312-316. 234. Vamvakopoulos N.C., Chrousos G.P. (1993) Structural Organization of the 5' Flanking Region of the Human Corticotropin Releasing Hormone Gene. J DNA Sequencing and Mapping 4:197-206. 235. DeBellis M., Chrousos G.P., Dorn L., Burke L., Helmers K., Kling M.A., Trickett P.K., Putnam F.W. (1994) Hypothalamic-Pituitary-Adrenal Axis Dysregulation in Sexually Abused Girls. J. Clin Endocrinol. Metab. 78:249-255. 236. Kling M., Demitrack M., Whitfield H. Jr., Kalogeras K., Listwak S., DeBellis M., Chrousos G.P., Gold P.W., Brandt H. (1993) Effects of the Glucocorticoid Antagonist RU 486 on Pituitary-Adrenal Function in Patients with Anorexia Nervosa and Healthy Volunteers: Enhancement of Plasma ACTH and Cortisol Secretion in Underweight Patients. Neuroendocrinol. 57:1082-1091. 237. Reincke M., Karl M., Travis W., Mastorakos G., Allolio B., Linehan M.H., Chrousos G.P., (1994) P53 Mutations in Human Adrenocortical Neoplasms: Immunohistochemical and Molecular Studies. J. Clin. Endocrinol. Metab. 78:790-794. 238. Cizza G., Kalogeras A.E., Brady L.S., Bagdy G., Bergamini E., Blackman M.R., Chrousos G.P., Gold P.W. (1994) Male 344 Fischer Rats Show a Progressive Central Impairment of the Hypothalamic-Pituitary- Adrenal-Axis with Advancing Age. Endocrinology 134:1611-1620. 239. Friedman T.C., Garcia-Borreguero D., Hardwick D., Akuete C.N., Stambuk M.K., Dorn G.B.Jr., Nieman L.K., Chrousos G.P. (1994) Diurnal Rhythm of Plasma Delta Sleep-Inducing Peptide in Humans: Evidence for Positive Correlation with Body Temperature and Negative Correlation with REM Slow Wave Sleep. J. Clin. Endocrin. & Metab. 78:1085-1089. 240. Karalis K., Mastorakos G., Chrousos G.P., Tolis G. (1994) Somatostatin Analogs Suppress the Inflammatory Reaction In Vivo. J. Clin. Invest. 93:2000-2006. 241. Kawatito Y., Sano H., Kawata M., Yuri K., Yamamura Y., Kato H., Chrousos G.P., Wilder R.L., Kondo M. 25
  26. 26. George P. Chrousos, M.D. (1994) Local Secretion of Corticotropin Releasing Hormone by Enterochromafin Cells in Human Colon. Gastroenterology 106:859-65. 242. Magiakou M.A., Mastorakos G., Oldfield E.H., Gomez M.T., Doppman J.L., Cutler G.B. Jr., Nieman L.K., Chrousos G.P. (1994) Cushing Syndrome in Children and Adolescents: Presentation, Diagnosis and Therapy. N. Engl. J. Med. 331:629-36. 243. Auchus R.J., Mastorakos G., Friedman T.C., Chrousos G.P. (1994) Corticotropin-Releasing Hormone Production by a Small Cell Carcinoma in a Patient with ACTH-dependent Cushing Syndrome. J. Endocrinol. Invest. 17:447-452. 244. Petrides J.S., Mueller G.P., Kalogeras K.T., Chrousos G.P., Gold P.W., Deuster P.A. (1994) Exercise- induced Activation of the Hypothalamic-Pituitary-Adrenal Axis: Marked Differences in the Sensitivity to Glucocorticoid Suppression. J. Clin. Endocrinol. Metab. 79:377-383. 245. Riddick L., Chrousos G.P., Jeffries S., Pang S. (1994) Comparison of Adrenocorticotropin and Adrenal Steroid Response to Corticotropin Releasing Hormone Versus Metyrapone Testing in Patients with Hypopituitarism. Pediatric Research 36:215-220. 246. Scopa C.D., Mastorakos M., Friedman T.C., Melachrinou M.C., Merino M.J., Chrousos G.P. (1994) Presence of Immunoreactive Corticotropin Releasing Hormone (CRH) in Thyroid Lesions. Am. J. Pathology 145:1159-1167. 247. Michelson D., Stone L., Galliven E., Magiakou M.A., Chrousos G.P., Sternberg E.M., Gold P.W. (1994) Multiple Sclerosis is Associated with Alterations in Hypothalamic-Pituitary-Adrenal Function. J. Clin. Endocrinol. Metab. 79:848-853. 248. Arai K., Tsigos C., Suzuki Y., Irony I., Karl M., Listwak S., Chrousos G.P. (1994) Physiological and Molecular Aspects of Mineralocorticoid Receptor Action in Pseudohypoaldosteronism: A Responsiveness Test and Therapy. J. Clin. Endocrinol. Metab. 79:1019-1023. 249. Mastorakos G., Scopa C., Friedman T., Vryonidou A., Kattis D., Phenekos K., Chrousos G.P. (1994) Presence of Immunoreactive Corticotropin Releasing Hormone in Normal and Polycystic Human Ovaries. J. Clin. Endocrinol. Metab. 79:934-939. 250. Mastorakos G., Weber J.S., Magiakou M.A., Gunn H., Chrousos G.P. (1994) Hypothalamic-Pituitary- Adrenal Axis Activation and Stimulation of Systemic Vasopressin Secretion by Recombinant Interleukin 6 in Humans: Potential Implications for the Syndrome of Inappropriate Vasopressin Secretion. J. Clin. Endocrinol. Metab. 79:1191-1197. 251. Magiakou M.A., Mastorakos G., Chrousos G.P. (1994) Final Stature in Patients with Endogenous Cushing Syndrome. J. Clin. Endocrinol. Metab. 79:1082-1085. 252. Patchev V.K., Brady L.S., Karl M., Chrousos G.P. (1994) Gene Expression of hsp90 and Glucocorticoid Receptors in the Brain: Evidence for Coordinate Regulation by Adrenal Steroid Levels In Vivo. Cell. Mol. Endocrinol. 103:57-64. 253. Stratakis C.A., Chrousos, G.P. (1994) Capillaritis (Purpura Simplex) Associated with Use of Aminoglutethimide in Cushing's Syndrome. Am. J. Hospital Pharmacy 51:2589-2591. 254. Beuschlein F., Reincke M., Karl M., Travis W.D., Jaursch-Hancke C., Abdelhamid S., Chrousos G.P., Allolio B. (1994) Clonal Composition of Human Adrenocortical Neoplasms. Cancer Research 54:4927- 4932. 26
  27. 27. George P. Chrousos, M.D. 255. Bernadini R., Chiarenza A., Kamilaris T.C., Renaud N., Lempereur L., Demitrack M., Gold P.W., Chrousos, G.P. (1994) In Vivo and In Vitro Effects of Arginine-Vasopressin Receptor Antagonists on the Hypothalamic-Pituitary-Adrenal Axis in the Rat. Neuroendocrinology 60:503-508. 256. Friedman T., Garcia D.B., Hardwick D., Akuete C., Doppman J., Dorn L., Barker C., Chrousos G.P. (1994) Decreased Delta Sleep and Plasma Delta Sleep-Inducing Peptide Immunoreactivity in Patients with Cushing Syndrome. Neuroendocrinology 60:626-634. 257. Crofford L.J., Pillemer S.R., Kalogeras K.T., Cash J.M., Michelson D., Kling M.A., Sternberg E.M., Gold P.W., Chrousos G.P., Wilder R.L. (1994) Hypothalamic-Pituitary-Adrenal-Axis Perturbation in Patients with Fibromyalgia. Arthritis and Rheumatism 37:1583-1592. 258. Michelson D., Chrousos G.P., Gold P.W. (1994) Type I Glucocorticoid Receptor Blockade Does Not Affect Baseline or Ovine Corticotropin-Releasing Hormone-Stimulated Adrenocorticotropic Hormone and Cortisol Secretion. NeuroImmunoModulation 1:274-277. 259. Mastorakos G., Cizza G., Kvetnansky R., Bergamini E., Blackman M.R., Gold P.W., Chrousos G.P. (1995) Aging and Acute Stress Decrease Corticotropin Releasing Hormone in the Ovary of the Fischer 344/N Rat. Life Sciences 56:1065-1071. 260. Latronico A.C., Reincke M., Mendonca B.B., Arai K., Mora P., Allolio B., Wajchenberg B.L., Chrousos, G.P., Tsigos C. (1995) No Evidence for Oncogenic Mutations in the Adrenocorticotropin Receptor (ACTH-R) Gene in Human Adrenocortical Neoplasms. J. Clin. Endocrinol. Metab. 80:875-877. 261. Arai K., Tsigos C., Suzuki Y., Listwak S., Zachman K., Zangeneh F., Rapaport R., Chanoine J.P., Chrousos G.P. (1995) No Apparent Mineralocorticoid Receptor Defect in a Series of Sporadic Cases of Pseudohypoaldosteronism. J. Clin. Endocrinol. Metab. 80:814-817. 262. Cizza G., Pacak K., Kvetnansky R., Palkovits M., Goldstein D.S., Brady L.S., Fukuhara K., Bergamini E., Kopin I.J., Blackman M.R., Chrousos G.P., Gold P.W. (1995) Decreased Stress Responsivity of the Central and Peripheral Catecholaminergic Systems in the Aged 344/N Fischer Rat. J. Clin. Invest. 95:1217-1224. 263. Heinrichs C., Deschepper J., Tsigos C., Drews R., Collu R., Dugardeyn C., Goyens P., Ghanem G.E., Bosson D., Chrousos G.P., Van Vliet G. (1995) Familial Adrenocorticotropin Unresponsiveness Associated with Alacrima and Achalasia: Biochemical and Molecular Studies in Two Siblings with Clinical Heterogeneity. European J. Peds. 154:191-196. 264. Bamberger C.M., Bamberger A.M., De Castro M., Chrousos G.P. (1995) Glucocorticoid Receptor- Beta, a Potential Endogenous Inhibitor of Glucocorticoid Action in Humans. J. Clin. Invest. 95:2435-2441. 265. Tsigos C., Arai K., Latronico A-C, DiGeorge A., Rapaport R., Chrousos G.P. (1995) A Novel Mutation of the Adrenocorticotropin Receptor (ACTH-R) Gene in a Family with the Syndrome of Isolated Glucocorticoid Deficiency but No ACTH-R Abnormalities in Two Families with Triple A Syndrome. J. Clin. Endocrinol. Metab. 80:2186-2189. 266. Mastorakos G., Patchev V.K., Chader G.J., Chrousos G.P., Gaudet S.J. (1995) Differences in arylakylamine N-Acetyltransferase Activity Between Inflammatory Disease-Susceptible Lewis and - Resistant Fischer Rats. Neuroendocrinology 62:71-78. 267. Doppman J.L., Nieman L.K., Chang R., Yanovski J.A., Cutler G.B. Jr., Chrousos G.P., Oldfield E.H. (1995) Selective Venous Sampling from the Cavernous Sinuses is not a More Reliable Technique than Sampling from the Inferior Petrosal Sinuses in Cushing Syndrome. J. Clin. Endocrinol. Metab. 80:2485- 2489. 27
  28. 28. George P. Chrousos, M.D. 268. Karalis K., Crofford L., Wilder R.L., Chrousos G.P. (1995) Glucocorticoid and/or Glucocorticoid Antagonist Effects in Inflammatory Disease-Susceptible Lewis and -Resistant Fischer Rats. Endocrinology 136:3107-3112. 269. Karalis K., Mastorakos G., Sano H., Davis C., Wilder R.L., Chrousos G.P. (1995) Somatostatin May Participate in the Antiinflammatory Actions of Glucocorticoids. Endocrinology 136:4133-4138. 270. Pacak K., McCarty R, Palkovitz M., Cizza G., Kopin I.J., Goldstein D., Chrousos G.P. (1995) Decreased Central and Peripheral Catecholaminergic Activation in Obese Zucker Rats. Endocrinology 136:4360- 4367. 271. Mastorakos G., Bouzas E., Caspi R., Friedman T., Chrousos G.P. (1995) Immune Corticotropin Releasing Hormone (CRH) is Present in the Eyes of and Promotes Experimental Autoimmune Uveoretinitis (EAU) in Rodents. Endocrinology 136:4650-4658. 272. Stratakis C.A., Mitsiadis N.S., Sun D., Chrousos G.P., O'Connell A. (1995) Recurring Oral Giant Cell Lesion in X-Linked Hypophosphatemic Rickets: Clinical Manifestation of Occult Hyperparathyroidism? J. Pediatrics 127:444-446. 273. Vgontzas A.N., Friedman T.C., Chrousos G.P., Bixler E.O., Vela-Bueno A., Kales A. (1995) Delta Sleep- Inducing Peptide in Normal Humans and in Patients with Sleep Apnea and Narcolepsy. Peptides 16:1153- 1156. 274. Dorn L.D., Burgess E.S., Dubbert B., Kling M., Gold P.W., Chrousos G.P. (1995) Psychopathology in Patients with Endogenous Cushing Syndrome: "Atypical" or "Melancholic" Features. Clin. Endocrinol. (Oxf.) 43:433-442. 275. Cizza G., Gold P.W., Chrousos G.P. (1995) The Stress-Induced Inhibition of the Hypothalamic- Pituitary- Thyroid Axis is Attenuated in the Aged Fischer 344/N Male Rat. Neuroendocrinology 62:506-13. 276. Theoharides T.C., Spanos C., Pang Z., Alferes L., Ligris K., Letourneau R., Rozniecki J.J., Webster E., Chrousos G.P. (1995) Stress-Induced Intracranial Mast Cell Degranulation. A Corticotropin-Releasing Hormone-Mediated Effect. Endocrinology 136:5745-50. 277. Yanovski J.A., Yanovski S.Z., Harrington L., Gold P., Chrousos G.P. (1995) Differences in the Hypothalamic-Pituitary-Adrenal Axis of Black and White Men. Hormone Research 44:208-212. 278. Chen H., Doppman J.L., Chrousos G.P., Norton J.A., Nieman L.K., Udelsman R. (1995) ACTH- Secreting Pheochromocytomas: The Exception to the Rule. Surgery 118:988-995. 279. Yu K.C., Alexander H.R., Ziessman H.A., Norton J.A., Buell J.F., Nieman L.K., Cutler Jr G.B., Chrousos G.P., Fraker D.L. (1995) The Role of Pre-Operative Iodocholesterol Scintiscanning in Patients Undergoing Adrenalectomy for Cushing's Syndrome. Surgery 118:981-987. 280. Amikura K., Alexander R.H., Norton J.A., Doppman J.L., Jensen R.T., Nieman L.K., Cutler G.B., Chrousos G.P., Fraker D.L. (1995) The Role of Surgery in Management of ACTH-Producing Islet Cell Tumors of the Pancreas. Surgery 118:1125-1130. 281. Kawahito Y., Sano H., Mukai S., Asai K., Kimura S., Yamamura Y., Kato H., Chrousos G.P., Wilder R.L., Kondo M. (1995) Corticotropin Releasing Hormone in Colonic Mucosa in Patients with Ulcerative Colitis. GUT 37:544-551. 282. Stratakis C.A., Carney A., Ping J., Papanicolaou D.A., Karl M., Kastner D.L., Pras E., Chrousos G.P. (1996) Carney Complex, a Familial Multiple Neoplasia and Lentiginosis Syndrome: Analysis of 11 28
  29. 29. George P. Chrousos, M.D. Kindreds and Linkage to the Short Arm of Chromosome 2. J. Clin. Invest. 97:699-705. 283. Karl M., Von Wichert G., Kempter E., Katz D.A., Reincke M., Monig H., Ali I.U., Stratakis C.A., Oldfield E.H., Chrousos G.P., Schulte H.M. (1996) Nelson's Syndrome Associated with a Somatic Frame Shift Mutation in the Glucocorticoid Receptor Gene. J. Clin. Endocrinol. Metab. 81:124-129. 284. Ghizzoni L., Mastorakos G., Vottero A., Magiakou M.A., Chrousos G.P., Bernasconi S. (1996) Spontaneous Cortisol and Growth Hormone Secretion Interactions in Patients with Nonclassic 21- Hydroxylase Deficiency (NCCAH) and Control Children. J. Clin. Endocrinol. Metab. 81:482-487. 285. Latronico A.C., Anasti J., Arnhold I.J.P., Rapaport R., Mendonca B.B., Bloise W., de Castro M., Tsigos G., Chrousos G.P. (1996) Testicular and Ovarian Resistance to Luteinizing Hormone Caused by Homozygous Inactivating Mutations of the Luteinizing Hormone Receptor Gene. N. Engl. J. Med. 334:507-512. 286. Johnson E.O., Decker L., Gold P.W., Chrousos G.P. (1996) Distribution of Hippocampal Mineralocorticoid and Glucocorticoid Receptor mRNA in a Glucocorticoid Resistant Nonhuman Primate. Steroids 61:69-73. 287. Petzke F., Heppner C., Mbulamberi D., Winkelmann W., Chrousos G.P., Allolio B., Reincke M. (1996) Hypogonadism in Rhodesian Sleeping Sickness: Evidence for Acute and Chronic Dysfunction of the Hypothalamic-Pituitary-Gonadal Axis. Fertility and Sterility 65:68-75. 288. Mastorakos G., Scopa C.D., Kao L.C., Vryonidou A., Friedman T.C., Kattis D., Phenekos C., Rabin D., Chrousos G.P. (1996) Presence of Immunoreactive Corticotropin Releasing-Hormone (CRH) in Human Endometrium. J. Clin. Endocrinol. Metab. 81:1046-1050. 289. Dorn L.D., Burgess E.S., Dichek H.L., Putnam F., Chrousos G.P., Gold P.W. (1996) Thyroid Hormone Concentrations in Depressed and Non-Depressed Adolescents: Group Differences and Behavioral Relations. J. Am. Acad. Child Adolesc. Psychiatry 35:299-306. 290. Leong, G.M., Mercado-Asis, L.B., Reynolds, J.C., Oldfield, E.H., Chrousos, G.P. (1996) The Effect of Cushing Disease on Bone Mineral Density, Body Composition, Growth and Puberty: A Report of an Identical Adolescent Twin Pair. J. Clin. Endocrinol. Metab. 81:1905-1911. 291. Magiakou, M.A., Mastorakos, G., Rabin, D., Dubbert, B., Gold, P.W., Chrousos, G.P. (1996) Hypothalamic Corticotropin Releasing Hormone Suppression during the Postpartum Period: Implications for the Increase of Psychiatric Manifestations during this Time. J. Clin. Endocrinol. Metab. 81:1912-1917. 292. Karl M., Saviolakis G.A., Gravanis A., Chrousos G.P., Margioris A.N. (1996) The PC 12 Rat Pheochromocytoma Cell Line Expresses the Prodynorphin Gene and Secretes the 8 kdalton Dynorphin Product. Regulatory Peptides 61:99-104. 293. Magiakou M.A., Mastorakos G., Rabin D., Margioris A.N., Dubbert B., Calogero A.E., Tsigos C., Munson P.J., Chrousos, G.P. (1996) The Maternal Hypothalamic-Pituitary-Adrenal Axis in Third Trimester Human Pregnancy. Clin. Endocrinol. (Oxf.) 44:419-428. 294. Kalogeras K.T., Nieman L.K., Friedman T.C., Dopppman J.L., Cutler G.B. Jr., Chrousos G.P., Wilder R.L., Gold P.W., Yanovski J.A. (1996) Inferior Petrosal Sinus Sampling in Normal Human Subjects Reveals a Unilateral Corticotropin-Releasing Hormone-Induced Arginine Vasopressin Release Associated with Ipsilateral Adrenal Corticotropin Secretion. J. Clin. Invest. 97:2045-2050 295. Johnson E.O., Kamilaris T.C., Calogero A.E., Gold P.W., Chrousos G.P. (1996) Effects of Early Parenting on Growth and Development in a Small Primate. Pediatric Research 39:999-1005. 29

×