FOR WEBSITE-- TO BE USED AS A LINK FOR THE
PEDIATRIC DEPARTMENT AND ANY OTHER LAB THAT
WISHES IT SO.
Developmental Origins of Endocrine Dysfunction
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The goal of this N.I.H. supported Training Program is to provide high
with a trainee while discussion
quality research training in one of two major tracks, Basic Science or
data or at a poster session---Do
Clinical Investigation and Epidemiology to pediatricians and basic
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scientists demonstrating a career commitment to academic pediatric
endocrinology and metabolism.
This program is centered in the Division of Pediatric Endocrinology,
Ddepartment of Pediatrics, Endocrine Division, but includes faculty
from other departments that offer an interdisciplinary research
environment for the successful training of young physician-scientist
in the specific area of mechanisms playing a role in the impact of early life events on endocrine
disorders in post-natal life. The program can also support candidates with a Ph.D. degree
seeking further training in endocrinology in a developmental context.
This training grant is a key aspect of the Pediatric Endocrine Subspecialty Training Program.
The Highlights of this Training Program Include:
• Research that uses clinical, cellular/molecular, physiological, and/or behavioral
approaches to tackle integrated questions.
• Research Mentors with expertise in a variety of problems and approaches that come from
• Increasing the breadth of training by including intellectual and technical training from two
mentors that represent the basic and clinical links to the chosen project.
• Coursework tailored to the individualized training needs of the trainee.
For more information, contact the Director or Associate Director of the
Director: Associate Director:
Delia M. Vazquez, M.D. Vasantha Padmanabham, Ph.D.
Associate Professor and Pediatric Endocrine Professor and Director of Pediatric
Fellowship Director Endocrine Research
Pediatric Endocrinology Training Program Faculty: Rank, Research Interest and Role
MENTOR AND RESEARCH TRACK RANK RESEARCH INTEREST
Christin Carter-Su, PhD Professor, Molecular and Growth/Diabetes: Growth hormone
Basic Science Track Integrative Physiology receptor structure and signal
William Herman, MD Professor, Internal Medicine, Diabetes: Diabetes, diabetes
Basic Science Track Endocrinology and complications, diabetes and
Clinical Investigation Track Epidemiology, Interim pregnancy, diabetes epidemiology,
Director, Michigan Diabetes managed care and health economics
Research and Training Center
Jeff Horowitz, PhD Assistant Professor, Division Obesity/Diabetes/Energy
Basic Science Track of Kinesiology Metabolism: regulation of fat and
Josephine Kasa-Vubu, MS, MD Assistant Professor, Obesity/Reproduction: Hormonal
Clinical Investigation Track Department of Pediatrics & regulation and insulin resistance in
Comm Diseases, Pediatric adolescent girls.
Theresa Lee, PhD Professor, Psychology & Behavior/Reproduction/Stress:
Basic Science Track Neuroscience Regulation of adult sex behavior by
prenatal exposure to excess sex
Ram Menon, MD Professor, Pediatrics & Comm Growth/Diabetes/Reproduction:
Basic Science Track Diseases & Physiology, Growth hormone action, regulation of
Director, Pediatric Endocrine gene transcription, and role of growth
Division and Molecular & factors in germ cell function.
Martin Myers Jr., MD, Ph.D. Assistant Professor Obesity/Diabetes:
Basic Science Track Internal Medicine and Type 2 diabetes, energy balance,
Physiology insulin, leptin
Vasantha Padmanabhan, PhD Professor, Pediatrics & Comm Reproduction/Growth:
Diseases, Obstetrics and Understanding the fetal origin of
Basic Science Track Gynecology, and Molecular & pubertal and adult reproductive and
Clinical Investigation Track Integrative Physiology metabolic disorders and the impact of
native steroids and estrogenic
environmental pollutants in
programming such defects.
Jessica Schwartz, PhD Professor, Molecular and Growth: Mechanisms for regulation
Basic Science Track Integrative Physiology; of gene expression by growth factors
Director, Cellular and
Molecular Biology Training
Robert Thompson, PhD Assistant Professor, Obesity/Reproduction: Modulation
Basic Science Track Psychiatry and Reproductive of processes leading to successful
Science and unsuccessful reproduction,
regulation lipid metabolism.
Delia M. Vazquez, MD Associate Professor, Stress/Growth/Behavior: Molecular
Basic Science Track Pediatrics & Comm Diseases, brain mechanisms underlying long-
Clinical Investigation Track Pediatric Endocrinology term consequences of stress in
Division, and Psychiatry; growing organisms & Consequences
Research Associate of prenatal and postnatal stress in
Professor, Center for Human infants and children
Growth and Development
Jon Kar Zubieta, MD, PhD Associate Professor, Stress Regulatory Mechanisms
Clinical Investigation Track Departments of Psychiatry, Examination of neurotransmitter
Radiology and Mental Health systems and neuronal nuclei involved
Research Institute in the stress response and emotional
regulation in humans with PET and
The Department of Pediatrics Division of Endocrinology provides an exciting and vigorous research setting for
faculty to perform the most advanced research aimed at understanding the pathophysiology of pubertal and adult
endocrine, behavioral, growth and reproductive disorders. The Faculty employ a wide array of integrative
molecular, cellular, physiologic and clinical approaches to explore fundamental questions relating to growth and
differentiation of tissues and the genes and signaling pathways involved in organ function and dysfunction. Both
animal and clinical models are effectively employed to gain an understanding of the origin and pathophysiology of
pediatric and adult endocrine diseases and develop strategies to prevent or manage diseases. Faculty with both
basic and clinical science research interests interact amongst themselves and with various members of the
University faculty to provide exciting preclinical, translational and clinical research opportunities. An NIH funded
Postdoctoral Research Training Program in Pediatric Endocrinology and Diabetes supported by 10
established investigators from 9 different departments at the University of Michigan facilitates high quality research
training for both pediatricians and basic scientists demonstrating a career commitment to academic pediatric
endocrinology and metabolism. The individual pediatric endocrinology faculty and their research areas are:
Department’s Web site
Delia M. Vazquez, M.D.
Developmental Origins of Endocrine Dysfunction
A Ppostdoctoral positions are is available to study mechanisms leading to Developmental Origins of Endocrine
Dysfunction. The candidate can choose among several targeted areas of pediatric endocrine research – growth,
metabolic syndrome, reproduction, and stress and behavior. Each research area is sponsored by one of 10
established investigators from 9 different departments at the University of Michigan who are exploring possible
mechanisms of endocrine dysfunction at a cellular and molecular, physiological, behavioral and/or clinical level in a
Qualifications: Applicants must hold a Ph.D. in physiology, bioengineering, cell and molecular biology, or a related
field from an accredited program. The position is funded by a recent training award from NIH-NIDDK. U.S.
citizenship or permanent resident status is necessary due to training grant requirements.
For further information visit our website at -------and contact individual investigators based on your research
interest. Please provide a CV, three letters of reference (or contact information), and a detailed cover letter
describing research experience, interests, and short and long term career goals.
Post-Doctoral Opportunity Advertisement
Another Version for Web site—which is too wordy….
Developmental Origins of Endocrine Dysfunction
This new postdoctoral research training program in Pediatric Endocrinology and Diabetes at the University of
Michigan has two main goals: 1) to provide high quality research training in one of two major tracks, Basic
Science or Clinical Investigation and Epidemiology to pediatricians and basic scientists demonstrating a career
commitment to academic pediatric endocrinology and metabolism, and 2) to provide an interdisciplinary research
environment for the successful training of young physician-scientist in the specific area of mechanisms playing a
role in the impact of early life events on endocrine disorders in post-natal life. The Pediatric Endocrinology
Training Program (PETP) will provide 2 years of intensive postdoctoral research training for M.D. and Ph.D.
trainees in an individualized and closely-mentored research training program designed to best fit each trainee’s
skills and interests. For the physician-scientist, this program will be integrated with the ongoing ACGME approved
fellowship program to include a one year intensive training in clinical pediatric endocrinology, which will be funded
with non-NIH monies. In order to provide outstanding mentorship for the trainees, the PETP will be actively
supported by 10 established investigators from 9 different departments at the University of Michigan, all with
extensive research and mentoring experience within their respective areas of expertise. Each trainee will be
mentored by a clinical/basic dyad of mentors to provide strong footing on hypothesis-driven translational research,
centering on developmental origin of endocrine diseases. The trainee will choose among several targeted areas of
pediatric endocrine research – growth, metabolic syndrome, reproduction, and stress and behavior. These areas
are chosen because of the established strengths of other University of Michigan research programs and
participating investigators in the PETP (see PETP Faculty, below). The overarching goal is to foster academic
careers that will improve children's health and thereby, the health of the population in the United States.