Embase® is a registered trademark of Elsevier BV.
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Presented by Ian Crowlesmith
25 S...
2
• Webinar control panel:
• ‘chat’ for questions or ‘ask a
question’
• minimize option for full screen
view
• Q&A halfway...
3
AGENDA
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. Embase vs MEDLINE
2. Adverse reac...
4
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. E...
5
DEFINITIONS OF ADVERSE EVENTS
ON EMBASE AND MEDLINE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events o...
6
ADVERSE DRUG REACTIONS REPORTED BY FDA
US AND NON-US ORIGIN (2003-2011)
Ian Crowlesmith | 25 September 2013 | Searching ...
7
ADVERSE DRUG REACTIONS: EMBASE VS MEDLINE
BASED ON SUBHEADINGS LINKED TO “CHEMICALS AND DRUGS”
Ian Crowlesmith | 25 Sept...
8
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. E...
9
ADVERSE REACTIONS IN EMBASE
BROWSING EMTREE TO FIND DRUG NAMES
Ian Crowlesmith | 25 September 2013 | Searching for Adver...
10
ADVERSE REACTIONS IN EMBASE
DRUG SEARCH
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
11
ADVERSE REACTIONS IN EMBASE
FILTERED TO LIST INDEXED DRUGS
Ian Crowlesmith | 25 September 2013 | Searching for Adverse ...
12
ADVERSE REACTIONS TO CISPLATIN
FILTERED TO LIST INDEXED DISEASES
Ian Crowlesmith | 25 September 2013 | Searching for Ad...
13
ADVERSE REACTIONS TO CISPLATIN
IN-DEPTH DRUG INDEXING
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Event...
14
ADVERSE REACTIONS TO CISPLATIN
EMBASE VS MEDLINE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on ...
15
OTHER ADVERSE EVENTS IN EMBASE
DRUG TOXICITY (SCOPE NOTE)
Ian Crowlesmith | 25 September 2013 | Searching for Adverse E...
16
ADVERSE EVENTS IN EMBASE
DRUG TOXICITY VS ADVERSE DRUG REACTION
Ian Crowlesmith | 25 September 2013 | Searching for Adv...
17
ADVERSE EVENTS IN EMBASE
ADDITIONAL SEARCH OPTIONS
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events o...
18
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. ...
19
SIDE EFFECTS IN EMTREE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
first 12
of over
10...
20
SEARCHING SIDE EFFECTS ON EMBASE
DISEASE SEARCH
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on E...
21
SEARCHING SIDE EFFECTS ON EMBASE
FILTER TO LIST INDEXED DISEASES
Ian Crowlesmith | 25 September 2013 | Searching for Ad...
22
INDEXING OF SIDE EFFECTS ON EMBASE
SIDE EFFECTS OF CISPLATIN
Ian Crowlesmith | 25 September 2013 | Searching for Advers...
23
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. ...
24
SEARCHING ADVERSE EVENTS USING KEYWORDS
“ADVERSE” AS A KEYWORD
Ian Crowlesmith | 25 September 2013 | Searching for Adve...
25
KEYWORDS FOR SEARCHING ADVERSE EVENTS
REPRESENTATIVE KEYWORDS
Ian Crowlesmith | 25 September 2013 | Searching for Adver...
26
SEARCHING ADVERSE EVENTS USING KEYWORDS
UNIQUE RECORDS RETRIEVED FOR CISPLATIN
Ian Crowlesmith | 25 September 2013 | Se...
27
SEARCHING FOR ADVERSE
EVENTS ON EMBASE
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
1. ...
28
ADVERSE EVENTS FOR MEDICAL DEVICES
REPORTED BY FDA (2004-2008)
Ian Crowlesmith | 25 September 2013 | Searching for Adve...
29
MEDICAL DEVICES ON EMTREE
NEW TREE STRUCTURE (2013)
Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events ...
30
FINDING ADVERSE EVENTS FOR MEDICAL DEVICES
DISEASE SUBHEADING “COMPLICATION”
Ian Crowlesmith | 25 September 2013 | Sear...
31
SEARCHING FOR ADVERSE EVENTS ON DEVICES
USING DISEASE SUBHEADING “COMPLICATION”
Ian Crowlesmith | 25 September 2013 | S...
32
SEARCHING FOR ADVERSE EVENTS ON DEVICES
RECORDS RETRIEVED USING KEYWORDS
Ian Crowlesmith | 25 September 2013 | Searchin...
33
SEARCHING FOR ADVERSE EVENTS ON DEVICES
TYPICAL RECORD FOUND USING KEYWORDS
Ian Crowlesmith | 25 September 2013 | Searc...
34
SEARCHING FOR ADVERSE EVENTS ON EMBASE
SUMMARY
Keyword searches
• Use keywords saved in „hedges‟
(saved searches) or al...
THANK YOU
ANY QUESTIONS?
35
Ian Crowlesmith
Senior Product Manager, Content
Development
i.crowlesmith@elsevier.com
Ian Cro...
36
Please fill in the survey
which will pop up at the
end of the webinar.
Ian Crowlesmith | 25 September 2013 | Searching ...
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Embase: Adverse Drug Reactions - webinar September 25 2013

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Ian Crowlesmith, our Embase expert reviewed the following in this webinar:
- Drugs and adverse drug reaction in Embase vs MEDLINE
- Searching for Adverse events and side effects in Embase
- Using keywords when searching for adverse events
- Adverse events of devices

Published in: Health & Medicine, Technology
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Embase: Adverse Drug Reactions - webinar September 25 2013

  1. 1. Embase® is a registered trademark of Elsevier BV. SEARCHING FOR ADVERSE EVENTS ON EMBASE Presented by Ian Crowlesmith 25 September 2013 i.crowlesmith@elsevier.com Your host: Ann-Marie Roche
  2. 2. 2 • Webinar control panel: • ‘chat’ for questions or ‘ask a question’ • minimize option for full screen view • Q&A halfway and last 10-15 minutes of the webinar NEED TO KNOW
  3. 3. 3 AGENDA Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching side effects 4. Using keywords 5. Adverse events of devices
  4. 4. 4 SEARCHING FOR ADVERSE EVENTS ON EMBASE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching side effects 4. Using keywords 5. Adverse events of devices
  5. 5. 5 DEFINITIONS OF ADVERSE EVENTS ON EMBASE AND MEDLINE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase Embase PubMed / MEDLINEfirst 4 of >100 terms "chemicals and drugs category/adverse effects"[MeSH Terms] NOT ("chemicals and drugs category/toxicity"[MeSH Terms] OR "chemicals and drugs category/poisoning"[MeSH Terms]) Search using: Search using: "chemicals and drugs”/exp/dd_ae only in humans
  6. 6. 6 ADVERSE DRUG REACTIONS REPORTED BY FDA US AND NON-US ORIGIN (2003-2011) Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/Adverse DrugEffects/ucm070441.htm
  7. 7. 7 ADVERSE DRUG REACTIONS: EMBASE VS MEDLINE BASED ON SUBHEADINGS LINKED TO “CHEMICALS AND DRUGS” Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 0 10,000 20,000 30,000 40,000 50,000 1990 1995 2000 2005 2010 Embase MEDLINE Publication year Records per year Embase includes all of MEDLINE Subheadings introduced in Embase (1988) Search strategy for Embase: "chemicals and drugs”/exp/dd_ae
  8. 8. 8 SEARCHING FOR ADVERSE EVENTS ON EMBASE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching for side effects 4. Using keywords 5. Adverse events of devices
  9. 9. 9 ADVERSE REACTIONS IN EMBASE BROWSING EMTREE TO FIND DRUG NAMES Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  10. 10. 10 ADVERSE REACTIONS IN EMBASE DRUG SEARCH Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  11. 11. 11 ADVERSE REACTIONS IN EMBASE FILTERED TO LIST INDEXED DRUGS Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  12. 12. 12 ADVERSE REACTIONS TO CISPLATIN FILTERED TO LIST INDEXED DISEASES Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  13. 13. 13 ADVERSE REACTIONS TO CISPLATIN IN-DEPTH DRUG INDEXING Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  14. 14. 14 ADVERSE REACTIONS TO CISPLATIN EMBASE VS MEDLINE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase Embase
  15. 15. 15 OTHER ADVERSE EVENTS IN EMBASE DRUG TOXICITY (SCOPE NOTE) Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  16. 16. 16 ADVERSE EVENTS IN EMBASE DRUG TOXICITY VS ADVERSE DRUG REACTION Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  17. 17. 17 ADVERSE EVENTS IN EMBASE ADDITIONAL SEARCH OPTIONS Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase This is a conference abstract This is an In-Process record
  18. 18. 18 SEARCHING FOR ADVERSE EVENTS ON EMBASE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching for side effects 4. Using keywords 5. Adverse events of devices
  19. 19. 19 SIDE EFFECTS IN EMTREE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase first 12 of over 100 terms
  20. 20. 20 SEARCHING SIDE EFFECTS ON EMBASE DISEASE SEARCH Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  21. 21. 21 SEARCHING SIDE EFFECTS ON EMBASE FILTER TO LIST INDEXED DISEASES Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  22. 22. 22 INDEXING OF SIDE EFFECTS ON EMBASE SIDE EFFECTS OF CISPLATIN Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  23. 23. 23 SEARCHING FOR ADVERSE EVENTS ON EMBASE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching for side effects 4. Using keywords 5. Adverse events of devices
  24. 24. 24 SEARCHING ADVERSE EVENTS USING KEYWORDS “ADVERSE” AS A KEYWORD Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  25. 25. 25 KEYWORDS FOR SEARCHING ADVERSE EVENTS REPRESENTATIVE KEYWORDS Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  26. 26. 26 SEARCHING ADVERSE EVENTS USING KEYWORDS UNIQUE RECORDS RETRIEVED FOR CISPLATIN Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase This is an In-Process record Outside AE definition for both Embase & MEDLINE
  27. 27. 27 SEARCHING FOR ADVERSE EVENTS ON EMBASE Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase 1. Embase vs MEDLINE 2. Adverse reactions on Embase 3. Searching for side effects 4. Using keywords 5. Adverse events of devices
  28. 28. 28 ADVERSE EVENTS FOR MEDICAL DEVICES REPORTED BY FDA (2004-2008) Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase http://clinicaldevice.typepad.com/cdg_e_conferences/adverse-events-and-effects/
  29. 29. 29 MEDICAL DEVICES ON EMTREE NEW TREE STRUCTURE (2013) Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  30. 30. 30 FINDING ADVERSE EVENTS FOR MEDICAL DEVICES DISEASE SUBHEADING “COMPLICATION” Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  31. 31. 31 SEARCHING FOR ADVERSE EVENTS ON DEVICES USING DISEASE SUBHEADING “COMPLICATION” Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  32. 32. 32 SEARCHING FOR ADVERSE EVENTS ON DEVICES RECORDS RETRIEVED USING KEYWORDS Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  33. 33. 33 SEARCHING FOR ADVERSE EVENTS ON DEVICES TYPICAL RECORD FOUND USING KEYWORDS Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase This record is a conference abstract !
  34. 34. 34 SEARCHING FOR ADVERSE EVENTS ON EMBASE SUMMARY Keyword searches • Use keywords saved in „hedges‟ (saved searches) or alerts. • Useful for Articles-in-Press, In- Process & Conference records. • This will increase sensitivity at the cost of precision. Medical devices • Search adverse effects using disease subheading CO. • Also consider expanding search using keywords. • Over 3000 medical devices are now available in Emtree. Adverse drug reactions • Use drug subheading AE where possible. Focus is on human. • Consider expanding search using keywords. • This will increase sensitivity at the cost of precision. Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  35. 35. THANK YOU ANY QUESTIONS? 35 Ian Crowlesmith Senior Product Manager, Content Development i.crowlesmith@elsevier.com Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase
  36. 36. 36 Please fill in the survey which will pop up at the end of the webinar. Ian Crowlesmith | 25 September 2013 | Searching for Adverse Events on Embase For more information and questions please use the contact details on our online page, where you may also find all training and support materials and our full webinar schedule. Our next Embase webinar is on October 23 and this will be an introduction to Embase for new users. AND FOR MORE INFORMATION …

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