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First, I would like to thank my parents who
supported me through all my life and are
always there for me when I need them.
I also wish to acknowledge Dr. Yoshikuni
Nagamine, who supervised me, and gave me the opportunity to develop my scientific
thinking and skills in his lab. While he offered scientific freedom, he was always available for discussions. I greatly appreciate that.
Thanks also to Prof. Gerhard Christofori and Prof. Fred Meins, the two other members of my thesis committee, for the advice they gave me during the committee meeting and for the time they will still have to invest to read and evaluate this thesis.
My special thanks go to Joshi Venugopal,
from whom I could learn a lot in many aspects of life and who became a close friend of mine. His critical and logical thinking inspired me in several things. I really appreciate the time we spent together.
I also want to acknowledge Malgorzata
Kiesielow for our fruitful collaboration and for
teaching me siRNA transfections.
In addition, I wish to thank my former and
current lab members Faisal, Hoanh, Fumiko,
Kacka, Sandra and Stephane. I always
enjoined working and spending some free time
with all of you.
Further, I want to acknowledge the technical
staff at the FMI who were always friendly and
helpful and made the scientific life at the FMI
much easier and productive. Thanks go to all
of the FMI members (especially from the
Hynes laboratory) and to all of those, who
provided me with scientific material: François
Lehembre, Kurt Ballmer, Tony Pawson, Peter
E. Shaw and Jerrold Olefsky. My thanks also
go to Pat King and Sara Oakley for critical
reading of my manuscripts.
My heartiest gratitude goes to Boris
Bartholdy who always supported me
scientifically with all of his skills and privately
with all of his love.