Reid RubsamenHIV/TB CLINICAL RESEARCHDURBAN
PheZulu Safari ParkZulu Hut       Zulu Tribe Performers
Caprisa Research and Treatment ClinicParallel work on TB and HIV
Tour GuidesAyesha KharsanyLulu Nair
Caprisa Clinic Intake Waiting RoomAll charts are electronic
On the RoofN95 respirator required for clinic tour
Neighborhood Across the StreetAmbulance driver training school
Caprisa Clinic PlacardsEducation      Facility Safety
Sample CollectionTB screening is primarily via sputum collection. PPD not useful in patients over five yearsold because of...
Counseling AreaLay counselors enroll patients in VOICE trial.
Counseling Session For VOICE TrialVaginal gel with anti-viral agents. >30% signal in 600 patient Phase IIb with peri-coita...
Study RegistrationFingerprint scanner eliminates possibility of co-enrollment (which was a problem with theVOICE Phase IIb...
Fingerprint AcquisitionFingerprint Scanner   Reid’s Thumbprint
Clinic-Based Data ManagementData-FAX system used.All HPP data sent toSHARPClinic has read-onlyaccess to OCRtranslated CRFs...
Clinical Trial ManagementAudits by NIH and Quintiles
Caprisa ClinicOperations Infrastructure   Clinic Video
The Medical SchoolMain Entrance
Medical School NeighborhoodLooking East   Looking West
Medical School Facility - HHMRIHoward Hughes Medical Research Institute under construction. P3 lab will be included forTB ...
Medical School Facility FocusHIV and TBFacility Directory   Detail
Medical School FacilityCaprisa Offices
Medical School FacilityReid and Salim Abdool Karim   Slim’s Office Entrance
Medical School FacilityNews clipping display   Bruce walker detail
Medical School FacilityBruce walker   Lab corridor
HIV Pathogenesis ProgrammeHPP Entity Poster   HPP Process Outline
Flow CytometryClinical FACS 4 wavelength FACS machineExpanded wavelength research FACS in same facility
All Positive Samples Frozen
Medical School Facility
Parallel TB ResearchStudy in-progress isevaluating the optimaltiming of co-delivery ofanti infective and antiviral agents ...
HPP Enabled StudiesSystematic tracking of patient cohorts in various HIV infection states allows for wide rangeof hypothes...
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Durban slides

  1. 1. Reid RubsamenHIV/TB CLINICAL RESEARCHDURBAN
  2. 2. PheZulu Safari ParkZulu Hut Zulu Tribe Performers
  3. 3. Caprisa Research and Treatment ClinicParallel work on TB and HIV
  4. 4. Tour GuidesAyesha KharsanyLulu Nair
  5. 5. Caprisa Clinic Intake Waiting RoomAll charts are electronic
  6. 6. On the RoofN95 respirator required for clinic tour
  7. 7. Neighborhood Across the StreetAmbulance driver training school
  8. 8. Caprisa Clinic PlacardsEducation Facility Safety
  9. 9. Sample CollectionTB screening is primarily via sputum collection. PPD not useful in patients over five yearsold because of prevalence of BCG vaccination.
  10. 10. Counseling AreaLay counselors enroll patients in VOICE trial.
  11. 11. Counseling Session For VOICE TrialVaginal gel with anti-viral agents. >30% signal in 600 patient Phase IIb with peri-coitaladministration. Sponsor wants daily dosing in Phase III. Quintiles is overseeing the PhaseIII study for Conrad Pharmaceuticals.
  12. 12. Study RegistrationFingerprint scanner eliminates possibility of co-enrollment (which was a problem with theVOICE Phase IIb trial).
  13. 13. Fingerprint AcquisitionFingerprint Scanner Reid’s Thumbprint
  14. 14. Clinic-Based Data ManagementData-FAX system used.All HPP data sent toSHARPClinic has read-onlyaccess to OCRtranslated CRFs for QCFingerprint scannereliminates possibility ofunauthorized co-enrollment
  15. 15. Clinical Trial ManagementAudits by NIH and Quintiles
  16. 16. Caprisa ClinicOperations Infrastructure Clinic Video
  17. 17. The Medical SchoolMain Entrance
  18. 18. Medical School NeighborhoodLooking East Looking West
  19. 19. Medical School Facility - HHMRIHoward Hughes Medical Research Institute under construction. P3 lab will be included forTB research.
  20. 20. Medical School Facility FocusHIV and TBFacility Directory Detail
  21. 21. Medical School FacilityCaprisa Offices
  22. 22. Medical School FacilityReid and Salim Abdool Karim Slim’s Office Entrance
  23. 23. Medical School FacilityNews clipping display Bruce walker detail
  24. 24. Medical School FacilityBruce walker Lab corridor
  25. 25. HIV Pathogenesis ProgrammeHPP Entity Poster HPP Process Outline
  26. 26. Flow CytometryClinical FACS 4 wavelength FACS machineExpanded wavelength research FACS in same facility
  27. 27. All Positive Samples Frozen
  28. 28. Medical School Facility
  29. 29. Parallel TB ResearchStudy in-progress isevaluating the optimaltiming of co-delivery ofanti infective and antiviral agents in patientsinfected with HIV andTB
  30. 30. HPP Enabled StudiesSystematic tracking of patient cohorts in various HIV infection states allows for wide rangeof hypothesis testing

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