Introducing Anodyne® Therapy

www.rapidhealing.com.au Introducing Anodyne Professional System Model 480 8 Pads Home System Model 120 4 Pads Mobile System OTG Back 1 Wrap Pad Anodyne® Therapy Systems

Monochromatic Single wavelength of light (890nm) Absorbed by hemoglobin Infrared Invisible to the human eye Penetrates the body by approximately 5 cm Energy 780 mw power per therapy pad Photo energy – not thermal Flexible Therapy Pads Maximizes efficacy and ease of use www.rapidhealing.com.au Introducing Anodyne What is Anodyne ® Technology? M onochromatic I nfra R ed E nergy (MIRE™)

Monochromatic

Single wavelength of light (890nm)

Absorbed by hemoglobin

Infrared

Invisible to the human eye

Penetrates the body by approximately 5 cm

Energy

780 mw power per therapy pad

Photo energy – not thermal

Flexible Therapy Pads

Maximizes efficacy and ease of use

IR is absorbed by hemoglobin and endothelial cells. Resultant photo-dissociation of NO from hemoglobin www.rapidhealing.com.au Introducing Anodyne Hypothesis of MIRE™

www.rapidhealing.com.au Introducing Anodyne Level of energy emitted with Anodyne vs. a Respond Laser (veterinary medicine for wound healing). Light does not have to be lased to penetrate the skin. Penetration of light through the hand. Notice how the veins absorb the light Anodyne Delivers Pulsed Photon Energy – not thermal energy – 780 mw per therapy pad Anodyne Pulsed Photon Energy Penetrates the Body

www.rapidhealing.com.au Introducing Anodyne Improved Microcirculation as s hown by Moore Scanning Laser Doppler Image after 20 minute treatment with Anodyne® Therapy compared with placebo (warmth) Baseline image Placebo 40% Increase MIRE™ 400% Increase Improved Microcirculation

www.rapidhealing.com.au Introducing Anodyne Improved Microcirculation as s hown by Moore Scanning Laser Doppler Image after 20 minute treatment with Anodyne® Therapy Improved Microcirculation Heel – 32x perfusion increase Sacral – 13x perfusion increase Knee – 20x perfusion increase

Vascular Neural Wound healing Anti-inflammatory Anti-bacterial Anti-viral Bone formation Pain relief www.rapidhealing.com.au Introducing Anodyne Vascular Effects of Nitric Oxide Dilates existing blood vessels (arterioles, venules, and lymphatics) Increases capillary (nutritional) flow Increases antibiotic efficacy Angiogenesis…grows new blood vessels Decreases edema/swelling/inflammation Increased venous evacuation Increased lymphatic motility Reduces platelet aggregation Nitric Oxide Has Many Positive Effects

Vascular

Neural

Wound healing

Anti-inflammatory

Anti-bacterial

Anti-viral

Bone formation

Pain relief

Vascular Effects of Nitric Oxide

Dilates existing blood vessels (arterioles, venules, and lymphatics)

Increases capillary (nutritional) flow

Increases antibiotic efficacy

Angiogenesis…grows new blood vessels

Decreases edema/swelling/inflammation

Increased venous evacuation

Increased lymphatic motility

Reduces platelet aggregation

If therapeutic objectives are to: Increase circulation Reduce inflammation Decrease edema (swelling) Enhance soft tissue remodeling Increase osteoblastic proliferation Reduce pain Increase sensation Far more effective than hot/cold packs, ultrasound, nerve stimulation www.rapidhealing.com.au Introducing Anodyne Indications for Use

If therapeutic objectives are to:

Increase circulation

Reduce inflammation

Decrease edema (swelling)

Enhance soft tissue remodeling

Increase osteoblastic proliferation

Reduce pain

Increase sensation

Far more effective than hot/cold packs, ultrasound, nerve stimulation

Inflammation/Infection Bursitis Osteoarthritis Tendonitis Plantar Fasciitis Lateral Epicondylitis Neuritis Synovitis Bell’s Palsy Cellulitis Osteomyelitis (IV Antibiotics)* Range of Motion Deficits Frozen Shoulder Contractures Orthopedic Non-Union/Jones Fractures Degenerative Disc Chronic Wounds Venous, Pressure Ulcers (Arterial) www.rapidhealing.com.au Case Studies Pain Neuralgia Fibromyalgia Neuropathic Pain Ischemic Pain Chronic Pelvic Pain Nerve Entrapments TMJ Carpal Tunnel Syndrome Tarsal Tunnel Swelling Edema Lymphedema Sprains and Strains Post-Operative Reduce Swelling and Pain Speed Healing Reduce Adhesions/Scarring * Depends on involvement Summary of Responsive Conditions

Inflammation/Infection

Bursitis

Osteoarthritis

Tendonitis

Plantar Fasciitis

Lateral Epicondylitis

Neuritis

Synovitis

Bell’s Palsy

Cellulitis

Osteomyelitis (IV Antibiotics)*

Range of Motion Deficits

Frozen Shoulder

Contractures

Orthopedic

Non-Union/Jones Fractures

Degenerative Disc

Chronic Wounds

Venous, Pressure Ulcers (Arterial)

Pain

Neuralgia

Fibromyalgia

Neuropathic Pain

Ischemic Pain

Chronic Pelvic Pain

Nerve Entrapments

TMJ

Carpal Tunnel Syndrome

Tarsal Tunnel

Swelling

Edema

Lymphedema

Sprains and Strains

Post-Operative

Reduce Swelling and Pain

Speed Healing

Reduce Adhesions/Scarring

Diabetes is a vascular disease Retinopathy Nephropathy Peripheral Neuropathy Autonomic Neuropathy (Gastroparesis; Silent Heart Attacks) Coronary Artery Disease Diabetic Patients Don’t Have Enough NO Reduced production of NO What little NO is produced is bound tightly to hemoglobin (HgA1c) Glucose destroys NO Therefore More vascular disease More pain (neuropathic; ischemic) More non-healing wounds www.rapidhealing.com.au Introducing Anodyne All symptoms that Anodyne® Therapy is scientifically proven to provide relief for! Why is Anodyne® Therapy Good For Diabetics?

Diabetes is a vascular disease

Retinopathy

Nephropathy

Peripheral Neuropathy

Autonomic Neuropathy (Gastroparesis; Silent Heart Attacks)

Coronary Artery Disease

Diabetic Patients Don’t Have Enough NO

Reduced production of NO

What little NO is produced is bound tightly to hemoglobin (HgA1c)

Glucose destroys NO

Therefore

More vascular disease

More pain (neuropathic; ischemic)

More non-healing wounds

Increased tensile strength of healed tissue Wounds don’t break down DPN ulcers don't reappear Reduced post-op complications Keloid scarring Dehiscence Infection rates Reduced post-operative pain Decreased edema Patients ambulating/back in shoes faster Faster return of range of motion www.rapidhealing.com.au Introducing Anodyne Observations over 10+ Years of Use in USA

Increased tensile strength of healed tissue

Wounds don’t break down

DPN ulcers don't reappear

Reduced post-op complications

Keloid scarring

Dehiscence

Infection rates

Reduced post-operative pain

Decreased edema

Patients ambulating/back in shoes faster

Faster return of range of motion