The Pistoia AllianceStrategy, Progress, Momentum<br />Ramesh Durvasula, PhD<br />Director, MSCO Informatics, Bristol-Myers...
Agenda<br />Industry Drivers<br />The Origins Pistoia Origins<br />The Mission and Strategy of Pistoia<br />The Initiative...
What is Core to your Business? What is Critical?<br />Core?<br />Yes<br />No<br />ExternalizeforBest Practices<br />Focus<...
Pistoia Membership<br />February2011<br />
The Mission of the Pistoia Alliance<br />Lowering the barriers to innovation by improving the interoperability of R&D busi...
Domains of Action<br />
The Focus of Each Domain<br />2010-2013<br />2012-2014<br />Biology<br />Chemistry<br />2012+<br />Scientific Collaboratio...
The Biology Domain<br />The Domain Strategy<br />Sequence Services<br />SESL<br />
Sequence<br />Services<br />Secure integrated multi-domain information services<br />Hosting/<br />integration of private ...
Sequence Services<br />
Sequence Services – the Rationale<br />“It takes all the running you can do, to keep in the same place!”  -- Red Queen<br />
Sequences & Cloud<br />
SESL<br />Semantic Enrichment of Scientific Literature<br />
Try this at your desk….<br />Which diseases are correlated to TCF7L2?<br />Gene/Protein<br />Literature – Full Text<br />L...
Try it again with Pistoia’s SESL….<br /><ul><li>Gene naming/synonyms
Gene Function
Literature statistics
Disease co-occurences
Gene/protein interactions</li></ul>…all in one report from one search<br />HOW?  A standard ontology, data model, query la...
The Deliverables of SESL<br />A Proof-of-Concept to demonstrate feasibility and clarify requirements<br />A functional spe...
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BioITWorldExpo - 2011April - The Pistoia Alliance

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BioITWorldExpo - 2011April - The Pistoia Alliance

  1. 1. The Pistoia AllianceStrategy, Progress, Momentum<br />Ramesh Durvasula, PhD<br />Director, MSCO Informatics, Bristol-Myers Squibb<br />Board Member of Pistoia Alliance<br />BioITWorld Expo, Boston, April 2011<br />
  2. 2. Agenda<br />Industry Drivers<br />The Origins Pistoia Origins<br />The Mission and Strategy of Pistoia<br />The Initiatives of Pistoia<br />
  3. 3. What is Core to your Business? What is Critical?<br />Core?<br />Yes<br />No<br />ExternalizeforBest Practices<br />Focus<br />Staff on Innovation<br />1990<br />Yes<br />Critical?<br />2011<br />No<br />Externalize for Cost Reduction<br />Reduce<br />Non-Value Added Work<br />
  4. 4. Pistoia Membership<br />February2011<br />
  5. 5. The Mission of the Pistoia Alliance<br />Lowering the barriers to innovation by improving the interoperability of R&D business processes….<br />….via pre-competitive collaborations<br />
  6. 6. Domains of Action<br />
  7. 7. The Focus of Each Domain<br />2010-2013<br />2012-2014<br />Biology<br />Chemistry<br />2012+<br />Scientific Collaboration<br />
  8. 8. The Biology Domain<br />The Domain Strategy<br />Sequence Services<br />SESL<br />
  9. 9.
  10. 10. Sequence<br />Services<br />Secure integrated multi-domain information services<br />Hosting/<br />integration of private data<br />ELIXIR<br />EATRIS<br />Security<br />Complexity of Service-Enablement<br />SAGE<br />caBIG<br />Large Scale<br />Analytics<br />…<br />SESL<br />Breadth of Information Integrated (content)<br />Sequences<br />Expression<br />Scientific Literature<br />Biology Domain Roadmap<br />
  11. 11. Sequence Services<br />
  12. 12. Sequence Services – the Rationale<br />“It takes all the running you can do, to keep in the same place!” -- Red Queen<br />
  13. 13. Sequences & Cloud<br />
  14. 14. SESL<br />Semantic Enrichment of Scientific Literature<br />
  15. 15. Try this at your desk….<br />Which diseases are correlated to TCF7L2?<br />Gene/Protein<br />Literature – Full Text<br />Literature - Abstracts<br />Gene expression<br />Inherited diseases<br />
  16. 16. Try it again with Pistoia’s SESL….<br /><ul><li>Gene naming/synonyms
  17. 17. Gene Function
  18. 18. Literature statistics
  19. 19. Disease co-occurences
  20. 20. Gene/protein interactions</li></ul>…all in one report from one search<br />HOW? A standard ontology, data model, query language, report structure, etc.<br />
  21. 21. The Deliverables of SESL<br />A Proof-of-Concept to demonstrate feasibility and clarify requirements<br />A functional specification for query brokering, result filtering, report generation<br />A potential for a new Business Model<br />
  22. 22. A Reality Check: Setting Expectations<br />vs.<br />vs.<br />
  23. 23. Our industry needs a Disruptive Innovation. The Disruption..is Pistoia<br />If you want to go FAST, go alone. <br />If you want to go FAR, go together.<br />
  24. 24. Thank you<br />

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