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New cholesterol treatment guidelines 2013

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This update represents the first major guideline revision since the National Cholesterol Education Program released …

This update represents the first major guideline revision since the National Cholesterol Education Program released
its Adult Treatment Panel III report in 2002

Published in: Health & Medicine

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  • 1. New Cholesterol Treatment Guideline2013 ACC-AHA Task Force Practice Guidelines November 12, 2013,
  • 2. Algorithm Patients >21 yr. of age without heart failure (NYHA class II, III, or IV) or end-stage renal disease (undergoing haemodialysis) Screen for cardiovascular risk factors, measure LDL cholesterol Clinical Clinical atherosclerotic atherosclerotic CVD CVD High-intensity statin therapy DM I or II & age of 40–75 yr and LDL 70–189 mg/dl Calculate 10-yr risk of atherosclerotic CVD If risk <7.5%, moderateintensity statin therapy If risk .7.5%, highintensity statin therapy No DM & age of 40– 75 yr & LDL 70–189 mg/dl Calculate 10-yr risk of atherosclerotic CVD LDL ≥ 190 mg/dl High-intensity statin therapy If risk .7.5%, moderate-tohighintensity statin therapy
  • 3. Intensity of statin therapy High-intensity statin therapy Moderate-intensity statin therapy Daily dose lowers LDL cholesterol level by approximately ≥50% on average Recommended: atorvastatin, 40 to 80 mg rosuvastatin, 20 to 40 mg  Daily dose lowers LDL cholesterol level by approximately 30 to <50% on average  Recommended: atorvastatin, 10 to 20 mg; rosuvastatin, 5 to 10 mg; simvastatin,20 to 40 mg; pravastatin, 40 to 80 mg; lovastatin, 40 mg; extended-release fluvastatin,80 mg; fluvastatin, 40 mg twice a day; pitavastatin, 2 to 4 mg
  • 4. 10 Year risk score calculator • http://my.americanheart.org/cvriskcalculator or at http://www.cardiosource.org/
  • 5. Advantage Only Statins Only LDL-Cholesterol
  • 6. Limitation: No Rx for Below 21 Years Above 75 yrs. without atheromatous disease Other risk factor like family Hx of Premature atheromatous disease have not been taken into consideration