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Actinomycosis

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  • 1. Actinomycetes www.freelivedoctor.com
  • 2. Actinomycetes (order)
    • Three genera
    • Actinomyces species
    • Nocardia species
    • Streptomyces species
    www.freelivedoctor.com
  • 3. Gram Positive Filamentous Bacteria www.freelivedoctor.com GENUS OXYGEN GRANULE ACIDFAST Mycobacteria aerobe no yes Actinomyces ANAEROBE YES no Nocardia aerobe sometime PARTIALLY Streptomyces aerobe YES no
  • 4. www.freelivedoctor.com
  • 5. Actinomycosis A chronic suppurative and granulomatous disease of the cervico-facial, thoracic or abdominal areas www.freelivedoctor.com
  • 6. Actinomycosis www.freelivedoctor.com
  • 7. Ecological Niche Actinomyces Endogenous (man and animals) www.freelivedoctor.com
  • 8. www.freelivedoctor.com
  • 9. CLINICAL SPECIMENS Actinomyces
    • Pus
    www.freelivedoctor.com
  • 10. Sulphur granules www.freelivedoctor.com
  • 11. www.freelivedoctor.com
  • 12. Drug of Choice
    • Penicillin
    • (large doses)
    www.freelivedoctor.com
  • 13. Serological Test
    • None available
    www.freelivedoctor.com
  • 14. www.freelivedoctor.com
  • 15. Nocardiosis
    • Subcutaneous infections, pulmonary infections, and brain abscesses
    www.freelivedoctor.com
  • 16. Ecological Association Soil Endogenous ? www.freelivedoctor.com
  • 17. Geographic Distribution
    • World wide
    www.freelivedoctor.com
  • 18. Nocardiosis
    • N. asteroides – Pulmonary
    • N. brasiliensis - Abscesses
    www.freelivedoctor.com
  • 19. www.freelivedoctor.com
  • 20. www.freelivedoctor.com
  • 21. Clinical Specimens
    • Sputum
    • Pus
    • Biopsy tissue
    www.freelivedoctor.com
  • 22. www.freelivedoctor.com
  • 23. Serological Test
    • None available
    www.freelivedoctor.com
  • 24. Drug of Choice Sulfamethoxazole-Trimethoprim www.freelivedoctor.com
  • 25. STREPTOMYCOSIS Streptomyces species www.freelivedoctor.com
  • 26. Mycetoma
    • Streptomyces species
    www.freelivedoctor.com
  • 27. Ecological Association Soil www.freelivedoctor.com
  • 28. www.freelivedoctor.com
  • 29. Streptomyces may invade bone www.freelivedoctor.com
  • 30. Clinical specimens Pus Biopsy material www.freelivedoctor.com
  • 31. www.freelivedoctor.com
  • 32. www.freelivedoctor.com
  • 33. Serological Test None available www.freelivedoctor.com
  • 34. Treatment
    • Surgical debridement
    • Sulfa drugs
    • Amphotericin B
    www.freelivedoctor.com
  • 35. www.freelivedoctor.com

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