Why Biotech faces the same       destiny as music industry                    @pietervboheemen            #CeBiTec CLIB GC...
Out with the old, in with the…22-3-2013     CLIB GC Symposium, Bielefeld, Germany   2
Social and Open Science22-3-2013    CLIB GC Symposium, Bielefeld, Germany   3
New momentum in science            What happens to the knowledge you create?               www.thecostofknowledge.com22-3-...
New momentum in policy                   Is Western Society tired of science?   Who needs science now that we have Dr. Goo...
New momentum in business            Forcing Big Pharma to get even                bigger is not a strategy22-3-2013       ...
A comparison in innovationComputers                           Biology     – 1980                                – 1980    ...
New momentum in society                                           Genomics                       HealthAnno 2013 society i...
DIYBio: Hardware                                          GoGoFugeOpenPCR.org                              BioCurious – DI...
DIYBio: Education                                                   Foo Camper’s Guide to Biological EngineeringDutch DIYB...
DIYBio: ScienceBrmlab (Prague) – Cognition experiments                                                               Kathe...
DIYBio: communities                                            BiologiGaragen22-3-2013    CLIB GC Symposium, Bielefeld, Ge...
DIYBio: Lab spaces                                                               GenSpace, New YorkLa Paillasse, Paris    ...
Waag Society Amsterdam22-3-2013    CLIB GC Symposium, Bielefeld, Germany   14
Strong DIYBio tradition22-3-2013     CLIB GC Symposium, Bielefeld, Germany   15
DIYBio in GermanyHannoverGEN                                                       BioTinkering, Berlin               Gree...
Why is IP important?                             2010 iGEM FinalistTU Delft iGEM Team 2010 – http://2010.igem.org/Team:TU_...
iGEM Parts Registry License            http://creativecommons.org/licenses/by/3.0/22-3-2013      CLIB GC Symposium, Bielef...
iGEM Parts Registry License            • Open Source = Open?             Note: You must have an iGEM account and be a memb...
New Registry on the RiseDIYBio Europe Kick Off Meeting – Paris, December 2012  22-3-2013                    CLIB GC Sympos...
How did DIYBio start            Amplino?            Dutch DIYBio Meetup, The Hague22-3-2013      CLIB GC Symposium, Bielef...
First shoe box PCR                                                                             Thermocycler               ...
Rapid Prototyping            Early Amplino Prototype22-3-2013       CLIB GC Symposium, Bielefeld, Germany   23
DIY environment            Bill and Melinda Gates Foundation – Flickr stream22-3-2013       CLIB GC Symposium, Bielefeld, ...
Grand Challenge, Big ImpactLack of adequate diagnostics: who is right?• Feachem, R. G. A. et al. Lancet (2010)• Roll Back ...
Current bio innovation modelTop DownInnovation-High risk-Big investments-Low output                             PatentOld ...
The problem with patents            • Limited use on global scale               – Especially developing world            •...
Glimpse of the future            Imagine:            • Information and designs are              freely available & easily ...
Information interpretation       Amplino Cloud Application - Crowsourcing disease surveillence22-3-2013                   ...
Award winning vision22-3-2013    CLIB GC Symposium, Bielefeld, Germany   30
Crossroad                                                                        2    Current knowledge society           ...
Concluding remarks                         • #1: IP law must maximize benefit to                           society        ...
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Why Biotech faces the same destiny as music industry

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Presented at CeBiTec CLIB GC symposium, Bielefeld on March 11, 2013

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Why Biotech faces the same destiny as music industry

  1. 1. Why Biotech faces the same destiny as music industry @pietervboheemen #CeBiTec CLIB GC symposium, Bielefeld22-3-2013 1
  2. 2. Out with the old, in with the…22-3-2013 CLIB GC Symposium, Bielefeld, Germany 2
  3. 3. Social and Open Science22-3-2013 CLIB GC Symposium, Bielefeld, Germany 3
  4. 4. New momentum in science What happens to the knowledge you create? www.thecostofknowledge.com22-3-2013 CLIB GC Symposium, Bielefeld, Germany 4
  5. 5. New momentum in policy Is Western Society tired of science? Who needs science now that we have Dr. Google?Knowledge, networks and nations – The Royal Society (2011) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 5
  6. 6. New momentum in business Forcing Big Pharma to get even bigger is not a strategy22-3-2013 CLIB GC Symposium, Bielefeld, Germany 6
  7. 7. A comparison in innovationComputers Biology – 1980 – 1980 – 2010 – 201022-3-2013 CLIB GC Symposium, Bielefeld, Germany 7
  8. 8. New momentum in society Genomics HealthAnno 2013 society is:-Post industrial Science Diagnostics-Networked Discovery-Knowledge based-International-Open Home brewing SynBio-Empowered Ecology Biology DIY Design Bio Microbiology Citizen Science Bioremediation Open Standards Workshops Education Self Teaching 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 8
  9. 9. DIYBio: Hardware GoGoFugeOpenPCR.org BioCurious – DIY Bio Printer 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 9
  10. 10. DIYBio: Education Foo Camper’s Guide to Biological EngineeringDutch DIYBio meetups and workshops - Gingko Bioworks 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 10
  11. 11. DIYBio: ScienceBrmlab (Prague) – Cognition experiments Katherine Aull, MIT, 2009MyDaughters DNA 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 11
  12. 12. DIYBio: communities BiologiGaragen22-3-2013 CLIB GC Symposium, Bielefeld, Germany 12
  13. 13. DIYBio: Lab spaces GenSpace, New YorkLa Paillasse, Paris Waag Society, AmsterdamIndieBiotech, Cork 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 13
  14. 14. Waag Society Amsterdam22-3-2013 CLIB GC Symposium, Bielefeld, Germany 14
  15. 15. Strong DIYBio tradition22-3-2013 CLIB GC Symposium, Bielefeld, Germany 15
  16. 16. DIYBio in GermanyHannoverGEN BioTinkering, Berlin GreenPeace.de 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 16
  17. 17. Why is IP important? 2010 iGEM FinalistTU Delft iGEM Team 2010 – http://2010.igem.org/Team:TU_Delft 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 17
  18. 18. iGEM Parts Registry License http://creativecommons.org/licenses/by/3.0/22-3-2013 CLIB GC Symposium, Bielefeld, Germany 18
  19. 19. iGEM Parts Registry License • Open Source = Open? Note: You must have an iGEM account and be a member of a current iGEM team or lab group in order to obtain parts from the Registry. If you would like to become an iGEM lab see igem.org to join. http://partsregistry.org/Help:Requesting_Parts http://igem.org/Lab_Registration_Handbook I can’t get my biobricks!?!22-3-2013 CLIB GC Symposium, Bielefeld, Germany 19
  20. 20. New Registry on the RiseDIYBio Europe Kick Off Meeting – Paris, December 2012 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 20
  21. 21. How did DIYBio start Amplino? Dutch DIYBio Meetup, The Hague22-3-2013 CLIB GC Symposium, Bielefeld, Germany 21
  22. 22. First shoe box PCR Thermocycler 100 90 80 70 Temperature (C) 60 50 40 30 20 10 0First Airplino Prototype 0 100 200 300 400 500 Time (sec) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 22
  23. 23. Rapid Prototyping Early Amplino Prototype22-3-2013 CLIB GC Symposium, Bielefeld, Germany 23
  24. 24. DIY environment Bill and Melinda Gates Foundation – Flickr stream22-3-2013 CLIB GC Symposium, Bielefeld, Germany 24
  25. 25. Grand Challenge, Big ImpactLack of adequate diagnostics: who is right?• Feachem, R. G. A. et al. Lancet (2010)• Roll Back Malaria Progress & Impact Series:Report 8 (WHO, 2011) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 25
  26. 26. Current bio innovation modelTop DownInnovation-High risk-Big investments-Low output PatentOld world is basedon informationmonopoly Steinmetz and Spack BMC Neurology (2009) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 26
  27. 27. The problem with patents • Limited use on global scale – Especially developing world • First to invent or First to file? • Business models based on patent trolling • Product life cycles are decreasing • Costs (time, money, energy)22-3-2013 CLIB GC Symposium, Bielefeld, Germany 27
  28. 28. Glimpse of the future Imagine: • Information and designs are freely available & easily shared • Fabrication is decentralized • Science is democratized, f.e. DIY diagnostics Copyleft biopiracy is on the rise22-3-2013 CLIB GC Symposium, Bielefeld, Germany 28
  29. 29. Information interpretation Amplino Cloud Application - Crowsourcing disease surveillence22-3-2013 CLIB GC Symposium, Bielefeld, Germany 29
  30. 30. Award winning vision22-3-2013 CLIB GC Symposium, Bielefeld, Germany 30
  31. 31. Crossroad 2 Current knowledge society Keep calm & carry on 1 3Backing winners, or challengers … or even losers?22-3-2013 CLIB GC Symposium, Bielefeld, Germany 31
  32. 32. Concluding remarks • #1: IP law must maximize benefit to society • Sharing is caring • Openness is good for science, society and business • Protect what you share – Always check the license of the journal or database you submit to. Look for Creative Commons or similar Share Alike licenses • Collaboration leads to innovation@pietervboheemen@amplino • Openness demands new businesswww.amplino.com modelspieter.van.boheemen@amplino.com 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 32

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