Why Biotech faces the same destiny as music industry

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Presented at CeBiTec CLIB GC symposium, Bielefeld on March 11, 2013

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Why Biotech faces the same destiny as music industry

  1. 1. Why Biotech faces the same destiny as music industry @pietervboheemen #CeBiTec CLIB GC symposium, Bielefeld22-3-2013 1
  2. 2. Out with the old, in with the…22-3-2013 CLIB GC Symposium, Bielefeld, Germany 2
  3. 3. Social and Open Science22-3-2013 CLIB GC Symposium, Bielefeld, Germany 3
  4. 4. New momentum in science What happens to the knowledge you create? www.thecostofknowledge.com22-3-2013 CLIB GC Symposium, Bielefeld, Germany 4
  5. 5. New momentum in policy Is Western Society tired of science? Who needs science now that we have Dr. Google?Knowledge, networks and nations – The Royal Society (2011) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 5
  6. 6. New momentum in business Forcing Big Pharma to get even bigger is not a strategy22-3-2013 CLIB GC Symposium, Bielefeld, Germany 6
  7. 7. A comparison in innovationComputers Biology – 1980 – 1980 – 2010 – 201022-3-2013 CLIB GC Symposium, Bielefeld, Germany 7
  8. 8. New momentum in society Genomics HealthAnno 2013 society is:-Post industrial Science Diagnostics-Networked Discovery-Knowledge based-International-Open Home brewing SynBio-Empowered Ecology Biology DIY Design Bio Microbiology Citizen Science Bioremediation Open Standards Workshops Education Self Teaching 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 8
  9. 9. DIYBio: Hardware GoGoFugeOpenPCR.org BioCurious – DIY Bio Printer 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 9
  10. 10. DIYBio: Education Foo Camper’s Guide to Biological EngineeringDutch DIYBio meetups and workshops - Gingko Bioworks 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 10
  11. 11. DIYBio: ScienceBrmlab (Prague) – Cognition experiments Katherine Aull, MIT, 2009MyDaughters DNA 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 11
  12. 12. DIYBio: communities BiologiGaragen22-3-2013 CLIB GC Symposium, Bielefeld, Germany 12
  13. 13. DIYBio: Lab spaces GenSpace, New YorkLa Paillasse, Paris Waag Society, AmsterdamIndieBiotech, Cork 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 13
  14. 14. Waag Society Amsterdam22-3-2013 CLIB GC Symposium, Bielefeld, Germany 14
  15. 15. Strong DIYBio tradition22-3-2013 CLIB GC Symposium, Bielefeld, Germany 15
  16. 16. DIYBio in GermanyHannoverGEN BioTinkering, Berlin GreenPeace.de 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 16
  17. 17. Why is IP important? 2010 iGEM FinalistTU Delft iGEM Team 2010 – http://2010.igem.org/Team:TU_Delft 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 17
  18. 18. iGEM Parts Registry License http://creativecommons.org/licenses/by/3.0/22-3-2013 CLIB GC Symposium, Bielefeld, Germany 18
  19. 19. iGEM Parts Registry License • Open Source = Open? Note: You must have an iGEM account and be a member of a current iGEM team or lab group in order to obtain parts from the Registry. If you would like to become an iGEM lab see igem.org to join. http://partsregistry.org/Help:Requesting_Parts http://igem.org/Lab_Registration_Handbook I can’t get my biobricks!?!22-3-2013 CLIB GC Symposium, Bielefeld, Germany 19
  20. 20. New Registry on the RiseDIYBio Europe Kick Off Meeting – Paris, December 2012 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 20
  21. 21. How did DIYBio start Amplino? Dutch DIYBio Meetup, The Hague22-3-2013 CLIB GC Symposium, Bielefeld, Germany 21
  22. 22. First shoe box PCR Thermocycler 100 90 80 70 Temperature (C) 60 50 40 30 20 10 0First Airplino Prototype 0 100 200 300 400 500 Time (sec) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 22
  23. 23. Rapid Prototyping Early Amplino Prototype22-3-2013 CLIB GC Symposium, Bielefeld, Germany 23
  24. 24. DIY environment Bill and Melinda Gates Foundation – Flickr stream22-3-2013 CLIB GC Symposium, Bielefeld, Germany 24
  25. 25. Grand Challenge, Big ImpactLack of adequate diagnostics: who is right?• Feachem, R. G. A. et al. Lancet (2010)• Roll Back Malaria Progress & Impact Series:Report 8 (WHO, 2011) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 25
  26. 26. Current bio innovation modelTop DownInnovation-High risk-Big investments-Low output PatentOld world is basedon informationmonopoly Steinmetz and Spack BMC Neurology (2009) 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 26
  27. 27. The problem with patents • Limited use on global scale – Especially developing world • First to invent or First to file? • Business models based on patent trolling • Product life cycles are decreasing • Costs (time, money, energy)22-3-2013 CLIB GC Symposium, Bielefeld, Germany 27
  28. 28. Glimpse of the future Imagine: • Information and designs are freely available & easily shared • Fabrication is decentralized • Science is democratized, f.e. DIY diagnostics Copyleft biopiracy is on the rise22-3-2013 CLIB GC Symposium, Bielefeld, Germany 28
  29. 29. Information interpretation Amplino Cloud Application - Crowsourcing disease surveillence22-3-2013 CLIB GC Symposium, Bielefeld, Germany 29
  30. 30. Award winning vision22-3-2013 CLIB GC Symposium, Bielefeld, Germany 30
  31. 31. Crossroad 2 Current knowledge society Keep calm & carry on 1 3Backing winners, or challengers … or even losers?22-3-2013 CLIB GC Symposium, Bielefeld, Germany 31
  32. 32. Concluding remarks • #1: IP law must maximize benefit to society • Sharing is caring • Openness is good for science, society and business • Protect what you share – Always check the license of the journal or database you submit to. Look for Creative Commons or similar Share Alike licenses • Collaboration leads to innovation@pietervboheemen@amplino • Openness demands new businesswww.amplino.com modelspieter.van.boheemen@amplino.com 22-3-2013 CLIB GC Symposium, Bielefeld, Germany 32

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