Fiber and glycemia in type 2 diabetes

1,994 views

Published on

This meta-analysis of randomized trials shows that increasing fiber intake has rather clear effect on fasting plasma glucose whereas the effect on HbA1c seems to be less profound

Published in: Health & Medicine
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
1,994
On SlideShare
0
From Embeds
0
Number of Embeds
421
Actions
Shares
0
Downloads
7
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Fiber and glycemia in type 2 diabetes

  1. 1. Post R et al. Dietary Fiber for the Treatment of Type 2 Diabetes Mellitus: A Meta-Analysis J Am Board Fam Med 2011; 25:16-23 http://twitter.com/pronutritionistPage 1
  2. 2. Page 2 Pronutritionist’s background • High intake of fiber is linked to improved cardiovascular outcomes in prospective cohort trials (Mente et al. 2009) • Current dietary guidelines emphasize the role of dietary fiber in the treatment of type diabetes (American diabetes association, 2008) • Exact magnitude of the effect of increased fiber intake, in the context of stable carbohydrate, fat and protein intake, is not known http://twitter.com/pronutritionistPage 2 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  3. 3. Methods (patients) • A metal-analysis of controlled randomized trials • Primary outcomes: – Fasting glucose – HbA1c • Participants: Type 2 diabetics • 15 trials included • On average, observed difference in fiber intake was 18,3 grams/day (40 grams per day) • Follow up: 3-12 weeks • Some trials used fiber supplements, some changed quality of bread or cereals • Both trials using soluble and in-soluble fiber were used http://twitter.com/pronutritionistPage 3 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  4. 4. Results http://twitter.com/pronutritionistPage 4 0,85 mmol/l 0,26 % Fasting blood glucose HbA1c Effect of increased fiber intake (18,3 g/d) vs placebo in T2D Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  5. 5. Pronutritionist’s discussion • This is the first meta-analysis to show the effect of increased fiber intake in the control of type 2 diabetes in randomized setting • The trials included were short. None of trials lasted more than 3 months. More long term data is needed • The meta-analysis supports the benefits of proposed high fiber intake in the current diabetes guidelines • If a diabetic patient is not able to increase use of vegetables, fruit and whole grain, supplementation of fiber is justified according to this meta- analysis • It will be interesting to see if novel approaches to control blood glucose will deliver similar effects, such as meal-time or bed-time vinegar intake (Liatis et al. 2010) http://twitter.com/pronutritionistPage 5 Post R et al. J Nutr. 2011 Dec;141(12):2180-5
  6. 6. Please read the whole paper at J Am Board Fam Med 2011; 25:16-23 http://twitter.com/pronutritionistPage 6
  7. 7. 12/05/14 http://twitter.com/pronutritionist http://www.facebook.com/pronutritionist http://www.pronutritionist.net Reijo Laatikainen, Authorized Nutritionist, MBA, Dietitian http://twitter.com/pronutritionistPage 7 Post R et al. J Nutr. 2011 Dec;141(12):2180-5

×