Global human growth hormone market 2012   koncept analytics
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Global human growth hormone market 2012 koncept analytics

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The global HGH report discusses the key ongoing trends like licensing agreement, development of needle free injectors and comparison between generic and biosimilar drug versions. On the industry ...

The global HGH report discusses the key ongoing trends like licensing agreement, development of needle free injectors and comparison between generic and biosimilar drug versions. On the industry development front, the current inclination is towards creating innovative therapeutic products with novel properties. Furthermore, the major factors driving the HGH market include rising cancer and CKD/ESRD cases and increasing GNI and healthcare expenditure on worldwide basis. In addition, a few factors posing challenges in front of the HGH industry are the off-label HGH use, associated risks and side effects and the escalating price pressure which, to an extent, are hindering the growth and development of the same.

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Global human growth hormone market 2012   koncept analytics Global human growth hormone market 2012 koncept analytics Presentation Transcript

  • View Report DetailsGlobal Human Growth Hormone Market---------------------------------------------- 2012
  • View Report DetailsExecutive SummaryPituitary - the master gland of human body is responsible for controlling crucial hormonal secretion, which, in turn, regulates other key aspects ofthe body such as temperature, growth, thyroid functioning, urination, and production of other hormones. It is a pea sized gland situated at thebase of brain and is a major component of human body as it expedites the response towards the surrounding environment and settings.Any deformity or damage to the pituitary gland can adversely impact the production and activity level of the above mentioned hormones, therebyaffecting the body work process and stunting the outcomes especially in the case of growth hormone. Marred pituitary function leads to eitherover or under secretion of the somatropin that is the growth hormone. Its over secretion causes disfiguration in the body parts like hands, face,feet, etc. whereas, its deficiency impedes the growth of body parts/whole body, thus leading to disease states like dwarfism or gigantism.It is observed that the growth hormone related problems usually affect children and teenagers, but it is seen to grip adults as well though to alesser extent. The major factors which vitiate the pituitary operations thus impairing the GH role include kidney malfunction, tumors/cancerespecially associated with brain. There are some other unknown causes as well which are termed as idiopathic. Earlier, to deal with thesepredicaments, growth hormone (GH) used to be extracted from the human cadavers but, as time passed and evolution oftechnology/tools/techniques/R&D took place, the extraction of GH also got altered and many novel innovations and discoveries were made in therespective field.Nowadays, many leading companies are heavily involved in the R&D process for devising longer acting and sustained release versions of thesomatropin which are produced using the recombinant technology. The competition prevalent in the respective industry is heating up day by day.The human growth hormone market (HGH) is monopolized by a few players viz. Pfizer, NovoNordisk, Eli Lilly and Roche.The global HGH report also discusses the key ongoing trends like licensing agreement, development of needle free injectors and comparisonbetween generic and biosimilar drug versions. On the industry development front, the current inclination is towards creating innovativetherapeutic products with novel properties. Furthermore, the major factors driving the HGH market include rising cancer and CKD/ESRD casesand increasing GNI and healthcare expenditure on worldwide basis. In addition, a few factors posing challenges in front of the HGH industry arethe off-label HGH use, associated risks and side effects and the escalating price pressure which, to an extent, are hindering the growth anddevelopment of the same.By combining SPSS Inc.’s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of theindustry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base todetermine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictorvariables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests.
  • Growth hormone (GH) is a type of peptide hormone produced by the body, responsible forstimulating cell reproduction, growth and regeneration amongst humans and animals Global HGH Market Share (2010) GHD (Growth Hormone Deficiency), occurs when the GH production is hampered. Any disruption in GH’s endogenous production causes adverse impact on the body processes, like muscle protein production, lipid catabolism, and other direct/indirect functions performed by the hormonal cascade. As of 2010, HGH market included NovoNordisk’s Norditropin, which constituted for around …….% of the global market share, Pfizer’s Genotropin with approximately ……%, followed by Roche’s Nutropin, and Eli Lilly’s Humatrope with ………% and ……..% shares, respectively. The global market for human growth hormone reached approximately US$.........billion based on key drug sales in 2010. Within the defined period of 6 years, this market registered a CAGR of ………% from US$...........billion in 2004 to reach US$........billion in 2010. Global Human Growth Hormone Market (2004-2010) According to IMS Health, in the US, the total sales of Saizen for 2010 and 2011 were approximately US$..... million and US$……….million, respectively. Another rHGH available in the market is manufactured by Pfizer, which it markets as Genotropin. The US sales of Genotropin for 2010 and 2011 were US$........million and US$...........million, respectively.
  • HGH is a protein hormone, naturally occurring, and is synthesized by the pituitary gland, responsible fornormal human growth and development especially among the teenagers and children Global hGH-CTP Market Opportunity (2014E-2020E) With the advent of novel technology in the field of medical sciences, it is now possible to develop rHGH in wet-labs by precisely combining the 191 amino acids which compose the peptide chain of the HGH. The global opportunity for Prolor’s hGH-CTP is projected to be US$......million for the year 2014, which is estimated to be worth US$.........million by 2020, rising at an impressive CAGR of ……….%. The GH market share in volume terms has been continuously Growth Hormone Volume Market share ………. in case of Pfizer, Eli Lilly and Roche thereby registering a modest …….. in all the cases over a ………. year (February 2007-February 2012) period. •Key Trends in the hGH market include: -Strategic Agreements -Inclination towards Needle-Free Injectors -Generic Vs Biosimilar Version of the drugs On the Industry development front, a lot many improved and long acting GH products are being developed and are undergoing clinical trials.
  • Disorders associated with GH depict the underlying lesions of pituitary, hypothalamus or inthe target cells Global HGH Market Forecast (2009-2015E) The global HGH market is forecasted to be US$.......billion in 2012 as compared to US$.......... billion estimated for the year 2011, registering a modest increase of roughly ………%. The same is expected to record a CAGR of about …….% for the period spanning 2010 to 2014 on the back of rising global cancer cases, global ESRD cases and GNI. The market for GH products is most evolved in the regions like Europe, the US and Japan wherein the GH products for use among infants constitute approximately …………% of the total GH demand. The challenges encountered by the industry include unapproved off-label uses of HGH, possible side effects and other associated risks and escalating price pressure. Note: Market attractiveness is inverse of penetration. Low penetration means high attractiveness and vice-versa
  • Table of Contents Tables and Charts 1. Human Growth Hormone List of Charts 1.1 Physiological Effects of Growth Hormone 1.2 GH Secretion Control GH’s Physiological Effect 1.3 GH Deficiency (GHD) GH Secretion Control Global HGH Market Share (2010) 1.3.1 Disease States Global Human Growth Hormone Market (2004-2010) Global hGH-CTP Market Opportunity (2014E-2020E) 1.4 Therapeutic and Other Uses of GH/HGH Market Share of Chemical Drugs and Biologics as per Drug Versions 1.5 Recombinant Human Growth Hormone (rHGH) Number of Cancer Cases Worldwide (2007-2011) Worldwide Patients with End Stage Renal Disease (2005-2011) 2. Global HGH Market Size Global Healthcare Spending (2005-2015E) World Gross National Income (2005-2010) Market Value Growth Hormone Volume Market share (February 2007-February Market Share 2012) Roche’s Revenues by Business Segments (2011) 2.1 HGH-CTP Market Opportunity Model Roche’s Revenues and Net Income, 2007-2011 2.2 SRhGH Market Opportunity Model Novo Nordisk Revenue Share by Business Segments (2011) Novo Nordisk Revenues & Net Income (2008-2011) 3. Market Dynamics Pfizer’s Revenue Share by Business Segments (2011) Pfizer’s Revenues & Net Income (2008-2011) 3.1 Key Trends Eli Lilly’s Revenues by Segment (2011) Eli Lilly’s Revenue and Net Income (2008-2011) 3.1.1 Strategic Agreements Global HGH Market Forecast (2009-2014E) 3.1.2 Inclination towards Needle-Free Injectors 3.1.3 Generic Vs Biosimilar Version of the drugs 3.2 Industry Developments 3.2.1 New Products under Development 3.3 Growth Drivers 3.3.1 Increasing Prevalence of Cancer 3.3.2 Increasing Cases Chronic Kidney Disease (CKD) 3.3.3 Rising Healthcare Expenditure 3.3.4 Increasing Global GNI (Gross National Income)
  • 3.4 Challenges Tables and Charts3.4.1 Unapproved/off-label Uses of HGH List of Tables3.4.2 Possible Side Effects and other Associated Risks3.4.3 Escalating Price Pressure Worldwide Revenues of Marketed hGH Products (2011) hGH-CTP US Market Opportunity Model (2014E-2020E)4. Competitive Landscape hGH-CTP European Market Opportunity Model (2014E-2020E) SRhGH Market Opportunity Model (2013E-2020E)Competitive Overview Annual US Sales of rHGH and InjectorsMarket Share LG Life Sciences Product under Development Sustained-release HGH under Development Worldwide5. Company Profiles Prolor’s Product under Development GH Products Devised by NovoNordisk5.1 Roche Holdings AG Growth Hormone Volume Market share (February 2007-February 2012)Business Overview Dependent & Independent Variables (2006-2011)Financial Overview Correlation MatrixBusiness Strategies Model Summary – Coefficient of DeterminationFocus On Innovative Pharmaceuticals Regression Coefficients OutputLeverage Expertise in Molecular Biology5.2 Novo NordiskBusiness OverviewFinancial OverviewBusiness StrategiesFocus on Hormone TherapyLeadership in Hemophilia Treatment5.3 Pfizer, Inc.Business OverviewFinancial OverviewBusiness StrategiesFocus on GrowthStrategic Acquisitions
  • 5.4 Eli Lilly and CompanyBusiness OverviewFinancial OverviewBusiness StrategiesFocus on Novel Therapeutic MoleculesCapacity Expansion6. Market Outlook6.1 Market Forecast6.2 Forecast Methodology6.2.1 Dependent and Independent Variables6.2.2 Correlation Analysis6.2.3 Regression Analysis
  • Contact Us: View Report DetailsThese are abridged and sanitized sample pages from the comprehensive report on the “Global Human Growth HormoneMarket”. To know more about this report or for any customized research requirement, please contact the following: Koncept Analytics CS-36, Second Floor, Ansal Plaza Vaishali, Ghaziabad, U.P. – 201010 Vikas Gupta T. +91-120-4130959 BD Manager C: +91-9811715635 vikas@konceptanalytics.com www.konceptanalytics.com