recent advances in antiepileptics

545 views
483 views

Published on

Published in: Health & Medicine
0 Comments
1 Like
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
545
On SlideShare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
81
Comments
0
Likes
1
Embeds 0
No embeds

No notes for slide
  • Despite a half century of significant advances in epilepsy therapy and diagnosGcs, treatment-.‐resistant seizures remain a problem for 1/3rd of paGents
  • This definition implies that a person with a single seizure, or recurrent seizures due to correctable or avoidable circumstances, does not necessarily have epilepsy. Epilepsy refers to a clinical phenomenon rather than a single disease entity,
  • Nmda-N methy D aspartate
  • biochemistry (electrolytes, urea and calcium)
  • Generalized seizure-Absence(Typical Atypical)Tonic clonic,Clonic,Tonic, Atonic, Myoclonic
  • Ketogenic diet-high fat,moderate protein and low carbohydrate
  • Ampa-alpha amino-3-hydroxy-5-methyl-4 isoxazole propionic acid.
  • serious adverse reactions, such as aplastic anaemia and hepatotoxicity due to formation of toxic metabolite, atropaldehyde, were discovered and hampered its use in predisposed patients with felbamate
  • Ampa-alpha amino-3-hydroxy-5-methyl-4isoxazole propionic acid.
  • Mechanism of action are still under investigation.
  • ×