Cave diver
Upcoming SlideShare
Loading in...5

Cave diver



FDA warns the consumers not to purchase Cave diver a herbal product promoted as sexual enhancer.

FDA warns the consumers not to purchase Cave diver a herbal product promoted as sexual enhancer.



Total Views
Views on SlideShare
Embed Views



0 Embeds 0

No embeds


Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
Post Comment
Edit your comment

Cave diver Cave diver Presentation Transcript

  • FDA warns against“Cave Diver”P.Naina MohamedPharmacologist - 
  •    IntroductionThe Food and Drug Administration (FDA) is advising consumers not to purchase or use “Cave Diver,” a product promoted and sold for sexual enhancement on various websites including and in some retail stores, on 10th June 2013.FDA laboratory analysis confirmed that “Cave Diver” contains sildenafil.
  • Possible Mechanism of ActionCave DiverContains SildenafilInhibition of Phosphodiesterase 5 (PDE 5)Inhibition of Breakdown of cGMPIncrease the concentration of cGMP in smooth muscle of corpuscavernosum and penile arteriesSmooth muscle relaxationIncrease the blood flow to corpus cavernosumPenile Erection
  • Interaction with NitratesUndeclared ingredient (Sildenafil)Interact with prescription drugs like nitrates (Nitroglycerin)Excessive dilation of smooth muscle of blood vesselsLower blood pressure to dangerous levelsHypotensionHeart Attack
  • Other InteractionsUndeclared ingredient (Sildenafil)Interacts with Alpha adrenergic blockers, otherantihypertensives or CYP3A4 enzymeinhibitors like Ketoconazole, Erythromycin,RitonavirLower blood pressureHypotension
  • ConclusionFDA warns the Consumers should stop using this productimmediately and throw it away.FDA advises the Consumers who have experienced any negativeside effects should consult a health care professional as soonas possible.FDA announces to the public of a growing trend of dietarysupplements or conventional foods with hidden drugs andchemicals. These products are typically promoted for sexualenhancement, weight loss, and body building, and are oftenrepresented as being “all natural.”FDA claims that they are unable to test and identify all productsmarketed as dietary supplements on the market that havepotentially harmful hidden ingredients.FDA advises the Consumers to exercise caution before purchasingany product in the above categories.
  • References Goodman & Gilmans The Pharmacological Basis ofTherapeutics, 12eLaurence L. Brunton, Bruce A. Chabner, Björn C. Knollmann Harrisons OnlineFeaturing the complete contents of Harrisons Principles ofInternal Medicine, 18eDan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L.Hauser, J. Larry Jameson, Joseph Loscalzo, Eds. Hursts The Heart, 13eValentin Fuster, Richard A. Walsh, Robert A. Harrington Basic & Clinical Pharmacology, 12eBertram G. Katzung, Susan B. Masters, Anthony J. Trevor Clinicians Pocket Reference, 11eLeonard G. Gomella, Steven A. Haist
  • References