Open Drug Discovery Teams

Open DrugDiscovery Teams (ODDT) http://slidesha.re/xzGhFH

A New Challenge Mid January Pistoia Alliance ask for volunteers to present in a Dragon’s Den scenario Feb 8th at the RSC Ideas that will transform Pharma R&D in 2014 So my natural response was :“If I am going to take part I want to create something real” http://bit.ly/wImJtHhttp://pistoiaalliance.org/

Could an app transform R&D ? Tuberculosis Kills 1.6-1.7m/yr (~1 every 8 seconds) equivalent to malaria No new drugs in over 40 yrs Pipeline is thin and weak BMGF & NIH do not coordinate TB efforts, not mandating open data. > 7000 rare diseases e.g. Jill Wood started a foundation, raises money, awareness, funds ground breaking research happening globally. She is in a race against time – what can we do to translate ideas from bench to patient faster? How can we help parents and families ?

Inspiration There are many 1000s of diseases and few with cures Science Online 2012 on open notebooks and data overload Flipboard Could we create an appfor science like Flipboard?

http://slidesha.re/why7gg

Within about 10 days Alex Clark Created ODDT to present at the Pistoia meetingFocused on Tuberculosis, Malaria, HIV/AIDS, Huntington’s Disease,Sanfilippo Syndrome, and Green Chemistry as topics in version 1We did not win the competition but had useful feedback – the need toarticulate the value proposition http://slidesha.re/GzVSPr

The Value Proposition The project is intended to bring together open data in a single aggregated collection, and then facilitate forming open research teams around this data Disseminate important information to a highly relevant target audience Network and discover other researchers with complementary interests, and opportunities to collaborate Team members will be able to borrow and reuse a growing collection of existing Open data. The community as a whole can debate, contest or endorse data based on its quality. The app could also be used as a type of “lab notebook” whereby individual researchers share links (URLs) to content and the app aggregates these. http://slidesha.re/weDFLg

Latest Layout9 Panels includes oneon ODDT informationCan use multipleTwitter accountsHere is my icon Stats summary About App

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Exposing rare diseases – creatingcommunities of researchers and sparking discussion My tweets on recent analyses and ideas My Retweets

Coming Soon From idea to appstore in ~2 months Available on appstore since April 12 Future versions will allow user to specify topics Presented at ACS Submitted business plan to ACS GCI  Rewards – badges  Beta version  More ideas that may need funding to cover server etc  - Would you fund us if we posted ODDT on Kickstarter or Petridish.org or IndieGoGo??  Are there sponsors for specific pages or content?

Thank you Alpha testers  Antony J. Williams  Hans De Winter  Chris Swain  Andrew Lang  Carlo Yuvienco  Paul Reinheimer  Michael S. Lajiness  Nancy Connell  Greta Beekhuis  Joe Hupcey III  Freundlich, Joel  Tanya Parrish  Peter Olinga ODDT  Peter CaduffPhoto for San Fillipo Syndrome courtesyof Jill Wood www.jonahsjustbegun.org

More Information Please contact us for further details or suggestions at: aclark@molmatinf.com and ekinssean@yahoo.com You can learn more about the ODDT app at: http://www.scimobileapps.com/index.php? title=Open_Drug_Discovery_TeamsAnd frequent blogs at http://www.collabchem.com and http://cheminf20.org/User guide now available at SlideShare http://slidesha.re/JcDTOsand FigShare http://bit.ly/IjR52V

Open Drug Discovery Teams

by Pistoia Alliance on May 05, 2012

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Open Drug Discovery Teams Presentation Transcript