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Chi ham ip-workshop_databases_demo_chile



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  • 1. Tutorial on Using Selected Patent Databases Cecilia Chi-Ham Director Science & Technology University of California, Davis, CA Tel: 530 754 6717 |
  • 2. Products may contain different patented parts and processes
  • 3. Freedom to Operate Source: ESA
  • 4. Forms of IP  Inventions and Know-  Plant Breeders how rights (Plant patents,  Patents and patent PVP) applications (territory and  Tangible property for specified period) (MTA)  Trade Secrets  Germplasm  Copyright  Cell lines  Corporate Identity  Transgenic mice  Domain names  Plasmids  Trademark i.e. Trademarks in Agriculture
  • 5. When to Conduct an FTO Search  FTO Search is a dynamic on-going analysis  Should be conducted as EARLY as possible in the research planning stages Ag-biotech Industry Intellectual Idea Property Research and Launch Development Regulatory 0-15 years ?? years Academia/Humanitarian Project Intellectual Idea Research and Property Re- Launch Development Regulatory Design
  • 6. Choosing an IP Database  Database content  Patent Collections  Geographical Coverage  Coverage (time-frame)  How frequently is the data uploaded  Search parameters  Keyword, citation, DNA sequence  DNA or Protein sequences  Size of the target technology—short peptides, PCR primers?  Drug targets  Methodologies or protocols  Output of data  Does the program allow you to export data? o Important when one needs to manipulate data o Format to export -- excel/access databases  Can you save, share the data?  Analytical tools
  • 7. Patent Database  Free  USPTO (Free and $ portals) o Patent Application Information Retrieval (PAIR): o Patents/applications o Patent assignment  European Patent Office  Google Patent  CAMBIA Patent Lens  NCBI:PubMed  Latipat  WIPO Directory of Int’l Offices:  PVP:  US TradeMark:  Subscription/fee based  GenomeQuest  Delphion Explore other Databases and Resources
  • 8. Class Demo 1: Trademark
  • 9.
  • 10. Class Demo 2: PVP
  • 11. Demonstration Task: Search for Plant Variety Protected in US 1. Peppers 2. bin/npgs/html/ Also can order database from UPOV website:
  • 12. PVP  IP rights granted to breeders of sexually propagated (seeds) or tuber-propagated plants  UPOV International Union for Protection of New Varieties of Plants  Ratified in 1968 with conventions in 1972, 1978, & 1991.  Protection timeframe:  20 yrs herbaceous  25 trees  Country specific  Requirements:  Distinct  Uniform  Stable
  • 13. bin/npgs/html/
  • 14. Pick most recent filings: 2004----2009
  • 15.
  • 16. Class Demo 1: NCBI
  • 17. NCBI: National Center for Biotechnology Information Useful for scientific and patent landscapes Demonstration Task: Identify patents related to Tomato E8 promoter to drive expression of a target gene (i.e. oral vaccine) in ripening fruit tissue 1. Identify DNA sequence for FTO Target Tomato Fruit E8 Promoter 2. Conduct preliminary DNA search using NCBI’s Patent Database
  • 18. Class Demo: Searching for Patents using NCBI Patent Database Tomato E8 Tissue Specific Promoter
  • 19. NCBI: National Center for Biotechnology Information Step 1. Go To: Step 2. Select Nucleotide Step 3. Search for: Tomato E8 Promoter Goal: Identify DNA sequence for FTO Target Tomato Fruit E8 Promoter
  • 20. Step 4. Select DQ317599: Lycopersicon esculentum ethylene- responsive fruit ripening (E8) gene, promoter and 5' flanking Step 5. Select Blast Sequences
  • 21. Step 6. Enter Tomato E8 promoter DNA sequence or its accession number DQ317599 DQ317599 Step 7. Select the Patent Sequences Databases Consider other parameters: i.e. word size, query subrange, data output etc.
  • 22. Step 11. Select Patent 5859330
  • 23. Step 12. Select Patent 5859330 Connects to USPTO
  • 24. Class Demo 2: Key Word Search
  • 25. Demonstration Task: IP search on Tomato E8 Promoter using Keyword and filtering based on Geography and Date of Publication 1. Using keywords search for related patents using PIPRA’s IP Database 2. Filter Features
  • 26. Class Demo: Searching for Patents using NCBI Patent Database Tomato E8 Tissue Specific Promoter
  • 27. More Options
  • 28. Geography US Tomato E8 Promoter In full text Search
  • 29. 696 IP Results
  • 30. E8 earliest Publication 1988 Last pub on promoter 1992 17-20 year patent life term 1976 1993
  • 31. Filtered from 696 records to 6 record BEFORE Publication.
  • 32. Class Demo 3: Family Tree IP in specific geographies
  • 33. Demonstration Task: IP search relevant in geographies where research will be performed: USA (research) G E Crop grown in Mexico Export Markets: Japan 1. Search for Family Tree 2. Find Status of Patents
  • 34. Patent Claims Promoter (CaMV35S) NPTII Kan Res A chimeric plant-expressible gene, said gene comprising in the 5' to 3' direction:  (a) a promoter region derived from a gene that is naturally expressed in a plant cell and that is capable of effecting mRNA transcription in the selected plant cell to be transfonned, operably linked to  (b) a structural DNA sequence encoding a polypeptide that permits the selection of transformed plant cells containing said chimeric gene by rendering said transformed plant cells resistant to an amount of an antibiotic that would be toxic to non-transformed plant cells, operably linked to  (c) a non-translated region of a gene naturally expressed in plant cells, said region encoding a signal sequence for polyadenylation of mRNA. Promoter Antibiotic Res
  • 35. Identify Potential Road Blocks Antibiotic selection of transgenic plants: GEOGRAPHICAL Australian World German Where will the research be done? What Countries will the products and its Japanese derivatives be marketed? US European US US
  • 36. Enter Patent US 6174724
  • 37. USA (research) G E Crop grown in Mexico Export Markets: Japan Japan IP Expired
  • 38. Reference Materials Chapter 14: Freedom to Operate and Risk Management: Chapter 14.3 How and Where to Search for IP Information on the World Wide Web: The “Tricks of the Trade” and an Annotated Listing of Web resources Chapter 14.2 Kowalski. Freedom to Operate: The Preparation Chapter 14.4 Fenton, Chi-Ham, and Boettiger. Freedom to Operate: The Law Firm’s Approach and Role Krattiger, Mahoney, Nelsen, Thomson, Bennett, Satyanarayana, Graff, Fernandez, and Kowalski. 2007. Intellectual Property Management in Health an Agricultural Innovation: a Handbook of Best Practices.
  • 39. Patent Database  Free  USPTO (Free and $ portals) o Patent Application Information Retrieval (PAIR): o Patents/applications o Patent assignment  European Patent Office  Google Patent  PIPRA Ag-IP  CAMBIA Patent Lens  NCBI:PubMed  Subscription/fee based  GenomeQuest  Delphion  MCAM  Others: Westlaw, Lexis, STN, etc. Explore other Databases and Resources
  • 40. Your Turn— Class Exercise
  • 41.  Divide into group of ~4:  Pick a key word or DNA sequence related to your research  See what kind of patents are being filed.  Are other people working in the same technology space  Is there a lot of patenting in this space  What countries are the technologies patented in  Who else is working in the same area  Select a plant variety  See who else is filing PVPs  Similar varieties  Summarize your results; share with the group