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<ul><li>THE WONDERFUL MOLECULE OF LIFE </li></ul>Shape of DNA What is DNA? Information in DNA Replication Summary What is ...
<ul><li>THE WONDERFUL MOLECULE OF LIFE </li></ul>Activities Videos Additional Info Previous Main Page Next Icon key
What is DNA? <ul><li>DNA is often called the blueprint of life. </li></ul><ul><li>In simple terms, DNA contains the instru...
<ul><li>Our genes are on our chromosomes. </li></ul><ul><li>Chromosomes are made up of a DNA. </li></ul>What is DNA?
The Shape of DNA <ul><li>DNA is a very long polymer. </li></ul><ul><li>The basic shape is like a twisted ladder or zipper....
The Structure of DNA <ul><li>The DNA double helix has two strands twisted together. </li></ul><ul><li>The backbone of the ...
<ul><li>DNA has four different nitrogen bases  </li></ul><ul><ul><li>Cytosine (C) Thymine (T) Adenine (A) Guanine (G) </li...
The Structure of DNA <ul><ul><li>Adenine and Thymine always join together </li></ul></ul><ul><ul><ul><li>A =  T </li></ul>...
Information in DNA <ul><li>Deoxyribonucleic Acid (DNA), is genetic material of all cellular organisms.  </li></ul><ul><li>...
DNA Replication <ul><li>The DNA molecule produces  2 IDENTICAL new complementary strands following the rules of base pairi...
<ul><li>DNA can “unzip” itself and RNA nucleotides match up to the DNA strand. </li></ul><ul><li>Both DNA & RNA are formed...
What is RNA? <ul><li>DNA contains the information for making proteins, but it does not make protein.  </li></ul><ul><li>Th...
Messenger RNA (mRNA) The Genetic Blueprint <ul><li>Messenger RNA is a copy of the genetic information that was transcribed...
DNA Transcription <ul><li>Transcription makes messenger RNA (mRNA) to carry the code for proteins out of the nucleus to th...
DNA vs mRNA <ul><li>DNA has deoxyribose, mRNA has ribose;  </li></ul><ul><li>DNA has 2 strands, mRNA has one strand;  </li...
Ribosomal RNA (rRNA) The Protein Factories <ul><li>Most of the RNA in cells is associated with small cellular structures k...
DNA Translation <ul><li>Translation assures that the right amino acids are joined together by peptides to form the correct...
Transfer RNA (tRNA) The Amino Acid Suppliers <ul><li>Transfer RNA is part of the process of translation. It brings the ami...
Summary <ul><li>Standard Powerpoint presentations work very well when they are being presented at the front of the room.  ...
© Mark E. Damon - All Rights Reserved Welcome to Jeopardy!
© Mark E. Damon - All Rights Reserved Round 1 0 0 0
© Mark E. Damon - All Rights Reserved Watson and Crick The Genetic Alphabet What are my chances? Inheritance Patterns G-ne...
© Mark E. Damon - All Rights Reserved $100 Watson and Crick's most famous discovery.
© Mark E. Damon - All Rights Reserved $100 What is the structure of DNA? Scores
© Mark E. Damon - All Rights Reserved $200 The country where Watson and Crick made their discovery.
© Mark E. Damon - All Rights Reserved $200 What is England?  Scores
© Mark E. Damon - All Rights Reserved $300 The term used to describe the structure of DNA.
© Mark E. Damon - All Rights Reserved $300 What is the double helix?  Scores
© Mark E. Damon - All Rights Reserved $400 The year Watson and Crick made their famous discovery.
© Mark E. Damon - All Rights Reserved $400 What is 1953? Scores
© Mark E. Damon - All Rights Reserved $500 The woman whose work Watson and Crick built upon to decipher the structure of D...
© Mark E. Damon - All Rights Reserved $500 Who is Rosalind Franklin? Scores
© Mark E. Damon - All Rights Reserved $100 Breast cancer susceptibility genes.
© Mark E. Damon - All Rights Reserved $100 What are BRCA1/2? Scores
© Mark E. Damon - All Rights Reserved $200 In DNA base-pairing, guanine binds with this nucleotide base?
© Mark E. Damon - All Rights Reserved $200 What is cytosine? Scores
© Mark E. Damon - All Rights Reserved $300 Guanine-cytosine base pairs involve this many hydrogen bonds.
© Mark E. Damon - All Rights Reserved $300 What is three? Scores
© Mark E. Damon - All Rights Reserved Daily Double
© Mark E. Damon - All Rights Reserved $400 FISH is an acronym for this cytogenetic technique.
© Mark E. Damon - All Rights Reserved $400 What is fluorescence in situ hybridization? Scores
© Mark E. Damon - All Rights Reserved $500 CAG repeat expansions cause diseases such as Huntington’s disease.  CAG codes f...
© Mark E. Damon - All Rights Reserved $500 What is glutamine? Scores
© Mark E. Damon - All Rights Reserved $100 The chance that my child will have a recessive disorder if both my husband and ...
© Mark E. Damon - All Rights Reserved $100 What is 25% or 1 in 4? Scores
© Mark E. Damon - All Rights Reserved $200 The risk that the son of a woman who carries an X-linked recessive disorder wil...
© Mark E. Damon - All Rights Reserved $200 What is 50% or 1/2? Scores
© Mark E. Damon - All Rights Reserved $300 Joey’s grandfather died of Huntington’s disease (an autosomal dominant disorder...
© Mark E. Damon - All Rights Reserved $300 What is 25% or 1 in 4?  (A ½  chance his mother inherited the at-risk allele, a...
© Mark E. Damon - All Rights Reserved $400 The carrier frequency of Cystic Fibrosis in the North American Caucasian popula...
© Mark E. Damon - All Rights Reserved $400 What is 1/25?  Scores
© Mark E. Damon - All Rights Reserved $500 Cindy and Tom have 2 boys with Duchenne’s Muscular Dystrophy.  The chance that ...
© Mark E. Damon - All Rights Reserved $500 What is nearly 0%?  Scores
© Mark E. Damon - All Rights Reserved $100 Consanguinity may be an indicator of this type of inheritance.
© Mark E. Damon - All Rights Reserved $100 What is recessive inheritance? Scores
© Mark E. Damon - All Rights Reserved $200 A type of inheritance that necessitates the disease presenting mainly in males.
© Mark E. Damon - All Rights Reserved $200 What is X-linked recessive inheritance? Scores
© Mark E. Damon - All Rights Reserved $300 A type of disease that can be inherited by both boys and girls, but only from t...
© Mark E. Damon - All Rights Reserved $300 What is a mitochondrial disorder? Scores
© Mark E. Damon - All Rights Reserved $400 This type of inheritance is involved in diseases such as sporadic cancer.
© Mark E. Damon - All Rights Reserved $400 What is multifactorial inheritance? Scores
© Mark E. Damon - All Rights Reserved $500 Huntington’s disease follows which pattern of inheritance?
© Mark E. Damon - All Rights Reserved $500 What is autosomal dominant inheritance? Scores
© Mark E. Damon - All Rights Reserved $100 Exons and introns are the main parts of these.
© Mark E. Damon - All Rights Reserved $100 What are genes? Scores
© Mark E. Damon - All Rights Reserved $200 A term for all of the genes and associated DNA found in human cells.
© Mark E. Damon - All Rights Reserved $200 What is the human genome? Scores
© Mark E. Damon - All Rights Reserved $300 A laboratory method used to visualize the results of a PCR reaction.
© Mark E. Damon - All Rights Reserved $300 What is gel electrophoresis? Scores
© Mark E. Damon - All Rights Reserved $400 One quarter of our DNA comes from each of these relatives.
© Mark E. Damon - All Rights Reserved $400 Who are our grandparents? Scores
© Mark E. Damon - All Rights Reserved $500 A genetics professional responsible for providing information on inherited diso...
© Mark E. Damon - All Rights Reserved $500 Who is a genetic counselor? Scores
© Mark E. Damon - All Rights Reserved $100
© Mark E. Damon - All Rights Reserved $100 What is a karyotype? Scores
© Mark E. Damon - All Rights Reserved $200
© Mark E. Damon - All Rights Reserved $200 What is a pedigree? Scores
© Mark E. Damon - All Rights Reserved $300
© Mark E. Damon - All Rights Reserved $300 What is amniocentesis? Scores
© Mark E. Damon - All Rights Reserved $400
© Mark E. Damon - All Rights Reserved $400 What is SKY? Scores
© Mark E. Damon - All Rights Reserved $500
© Mark E. Damon - All Rights Reserved $500 Who are Watson and Crick? Scores
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Transcript of "DNA"

  1. 1. <ul><li>THE WONDERFUL MOLECULE OF LIFE </li></ul>Shape of DNA What is DNA? Information in DNA Replication Summary What is RNA? Transcription Translation Jeopardy
  2. 2. <ul><li>THE WONDERFUL MOLECULE OF LIFE </li></ul>Activities Videos Additional Info Previous Main Page Next Icon key
  3. 3. What is DNA? <ul><li>DNA is often called the blueprint of life. </li></ul><ul><li>In simple terms, DNA contains the instructions for making proteins within the cell. </li></ul>Click here for a closer look
  4. 4. <ul><li>Our genes are on our chromosomes. </li></ul><ul><li>Chromosomes are made up of a DNA. </li></ul>What is DNA?
  5. 5. The Shape of DNA <ul><li>DNA is a very long polymer. </li></ul><ul><li>The basic shape is like a twisted ladder or zipper. </li></ul><ul><li>This is called a double helix. </li></ul><ul><li>The structure of DNA was discovered by James Watson & Francis Crick </li></ul>WATSON & CRICK
  6. 6. The Structure of DNA <ul><li>The DNA double helix has two strands twisted together. </li></ul><ul><li>The backbone of the molecule is alternating phosphate and deoxyribose, a sugar, parts. </li></ul><ul><li>The teeth are nitrogenous bases. </li></ul>Click here for a closer look
  7. 7. <ul><li>DNA has four different nitrogen bases </li></ul><ul><ul><li>Cytosine (C) Thymine (T) Adenine (A) Guanine (G) </li></ul></ul><ul><li>The bases attract each other because of hydrogen bonds. </li></ul><ul><li>Hydrogen bonds are weak but there are millions and millions of them in a single molecule of DNA. </li></ul>
  8. 8. The Structure of DNA <ul><ul><li>Adenine and Thymine always join together </li></ul></ul><ul><ul><ul><li>A = T </li></ul></ul></ul><ul><ul><li>Cytosine and Guanine always join together </li></ul></ul><ul><ul><ul><li>C = G </li></ul></ul></ul>
  9. 9. Information in DNA <ul><li>Deoxyribonucleic Acid (DNA), is genetic material of all cellular organisms. </li></ul><ul><li>DNA carries the information needed to direct protein synthesis and replication. </li></ul><ul><li>Protein synthesis is the production of the proteins needed by the cell for its activities and development. </li></ul>
  10. 10. DNA Replication <ul><li>The DNA molecule produces 2 IDENTICAL new complementary strands following the rules of base pairing: </li></ul><ul><ul><li>A-T, G-C </li></ul></ul><ul><li>Each strand of the original DNA serves as a template for the new strand </li></ul>As cells grow and divide the cell must make more DNA to carry out the functions of the cell.
  11. 11. <ul><li>DNA can “unzip” itself and RNA nucleotides match up to the DNA strand. </li></ul><ul><li>Both DNA & RNA are formed from NUCLEOTIDES and are called NUCLEIC acids. </li></ul>
  12. 12. What is RNA? <ul><li>DNA contains the information for making proteins, but it does not make protein. </li></ul><ul><li>There are 3 forms of RNA that are responsible for using the information stored in DNA to make protein. </li></ul><ul><ul><li>mRNA rRNA tRNA </li></ul></ul>DNA RNA
  13. 13. Messenger RNA (mRNA) The Genetic Blueprint <ul><li>Messenger RNA is a copy of the genetic information that was transcribed from the cell’s DNA. </li></ul><ul><li>It is like a ‘blueprint’ of the genetic information and is brought to the ribosome and translated into protein with the help of tRNA. </li></ul>
  14. 14. DNA Transcription <ul><li>Transcription makes messenger RNA (mRNA) to carry the code for proteins out of the nucleus to the ribosomes in the cytoplasm. </li></ul><ul><li>RNA polymerase binds to DNA, separates the strands, then uses one strand as a template to assemble mRNA. </li></ul>
  15. 15. DNA vs mRNA <ul><li>DNA has deoxyribose, mRNA has ribose; </li></ul><ul><li>DNA has 2 strands, mRNA has one strand; </li></ul><ul><li>DNA has thymine, mRNA has uracil. </li></ul>
  16. 16. Ribosomal RNA (rRNA) The Protein Factories <ul><li>Most of the RNA in cells is associated with small cellular structures known as ribosomes, the protein factories of the cells. </li></ul><ul><li>Ribosomes are the site of Translation , where mRNA arrives with genetic instructions for building proteins from amino acid monomers brought by tRNA. </li></ul>
  17. 17. DNA Translation <ul><li>Translation assures that the right amino acids are joined together by peptides to form the correct protein. </li></ul><ul><li>The cell uses information from mRNA to produce proteins. </li></ul>
  18. 18. Transfer RNA (tRNA) The Amino Acid Suppliers <ul><li>Transfer RNA is part of the process of translation. It brings the amino acid coded for by mRNA, and these amino acids are joined together to form proteins. </li></ul>
  19. 19. Summary <ul><li>Standard Powerpoint presentations work very well when they are being presented at the front of the room. Standard Powerpoint presentations are designed to run from the first slide to the last. My Powerpoint presentation takes a slightly different approach to the standard presentation. I designed this presentation to be used by a presenter or as an interactive learning aid for students to use on their own. This presentation allows the students to skip back and fourth between topics to check things that they did not quite understand the first time around. With this presentation the student can jump past stuff that they already know and go directly to the topic that interest them. I achieved this effect by creating hyperlinks that were designed to look like buttons. I also, added hyperlinks to different websites that contain review activities, additional information, and video clips that will allow the learner to gain a greater understanding about the topic. </li></ul>
  20. 20. © Mark E. Damon - All Rights Reserved Welcome to Jeopardy!
  21. 21. © Mark E. Damon - All Rights Reserved Round 1 0 0 0
  22. 22. © Mark E. Damon - All Rights Reserved Watson and Crick The Genetic Alphabet What are my chances? Inheritance Patterns G-netics Genetic Photo Gallery $100 $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500 $500 Scores
  23. 23. © Mark E. Damon - All Rights Reserved $100 Watson and Crick's most famous discovery.
  24. 24. © Mark E. Damon - All Rights Reserved $100 What is the structure of DNA? Scores
  25. 25. © Mark E. Damon - All Rights Reserved $200 The country where Watson and Crick made their discovery.
  26. 26. © Mark E. Damon - All Rights Reserved $200 What is England? Scores
  27. 27. © Mark E. Damon - All Rights Reserved $300 The term used to describe the structure of DNA.
  28. 28. © Mark E. Damon - All Rights Reserved $300 What is the double helix? Scores
  29. 29. © Mark E. Damon - All Rights Reserved $400 The year Watson and Crick made their famous discovery.
  30. 30. © Mark E. Damon - All Rights Reserved $400 What is 1953? Scores
  31. 31. © Mark E. Damon - All Rights Reserved $500 The woman whose work Watson and Crick built upon to decipher the structure of DNA.
  32. 32. © Mark E. Damon - All Rights Reserved $500 Who is Rosalind Franklin? Scores
  33. 33. © Mark E. Damon - All Rights Reserved $100 Breast cancer susceptibility genes.
  34. 34. © Mark E. Damon - All Rights Reserved $100 What are BRCA1/2? Scores
  35. 35. © Mark E. Damon - All Rights Reserved $200 In DNA base-pairing, guanine binds with this nucleotide base?
  36. 36. © Mark E. Damon - All Rights Reserved $200 What is cytosine? Scores
  37. 37. © Mark E. Damon - All Rights Reserved $300 Guanine-cytosine base pairs involve this many hydrogen bonds.
  38. 38. © Mark E. Damon - All Rights Reserved $300 What is three? Scores
  39. 39. © Mark E. Damon - All Rights Reserved Daily Double
  40. 40. © Mark E. Damon - All Rights Reserved $400 FISH is an acronym for this cytogenetic technique.
  41. 41. © Mark E. Damon - All Rights Reserved $400 What is fluorescence in situ hybridization? Scores
  42. 42. © Mark E. Damon - All Rights Reserved $500 CAG repeat expansions cause diseases such as Huntington’s disease. CAG codes for this amino acid.
  43. 43. © Mark E. Damon - All Rights Reserved $500 What is glutamine? Scores
  44. 44. © Mark E. Damon - All Rights Reserved $100 The chance that my child will have a recessive disorder if both my husband and I carry the disease allele for the same disorder.
  45. 45. © Mark E. Damon - All Rights Reserved $100 What is 25% or 1 in 4? Scores
  46. 46. © Mark E. Damon - All Rights Reserved $200 The risk that the son of a woman who carries an X-linked recessive disorder will have the disorder.
  47. 47. © Mark E. Damon - All Rights Reserved $200 What is 50% or 1/2? Scores
  48. 48. © Mark E. Damon - All Rights Reserved $300 Joey’s grandfather died of Huntington’s disease (an autosomal dominant disorder). The chance that Joey will also have the disease.
  49. 49. © Mark E. Damon - All Rights Reserved $300 What is 25% or 1 in 4? (A ½ chance his mother inherited the at-risk allele, and ½ chance Joey inherited the at risk allele) Scores
  50. 50. © Mark E. Damon - All Rights Reserved $400 The carrier frequency of Cystic Fibrosis in the North American Caucasian population?
  51. 51. © Mark E. Damon - All Rights Reserved $400 What is 1/25? Scores
  52. 52. © Mark E. Damon - All Rights Reserved $500 Cindy and Tom have 2 boys with Duchenne’s Muscular Dystrophy. The chance that the baby girl that Cindy is currently carrying will also have DMD (an X-linked recessive disorder)?
  53. 53. © Mark E. Damon - All Rights Reserved $500 What is nearly 0%? Scores
  54. 54. © Mark E. Damon - All Rights Reserved $100 Consanguinity may be an indicator of this type of inheritance.
  55. 55. © Mark E. Damon - All Rights Reserved $100 What is recessive inheritance? Scores
  56. 56. © Mark E. Damon - All Rights Reserved $200 A type of inheritance that necessitates the disease presenting mainly in males.
  57. 57. © Mark E. Damon - All Rights Reserved $200 What is X-linked recessive inheritance? Scores
  58. 58. © Mark E. Damon - All Rights Reserved $300 A type of disease that can be inherited by both boys and girls, but only from their mother?
  59. 59. © Mark E. Damon - All Rights Reserved $300 What is a mitochondrial disorder? Scores
  60. 60. © Mark E. Damon - All Rights Reserved $400 This type of inheritance is involved in diseases such as sporadic cancer.
  61. 61. © Mark E. Damon - All Rights Reserved $400 What is multifactorial inheritance? Scores
  62. 62. © Mark E. Damon - All Rights Reserved $500 Huntington’s disease follows which pattern of inheritance?
  63. 63. © Mark E. Damon - All Rights Reserved $500 What is autosomal dominant inheritance? Scores
  64. 64. © Mark E. Damon - All Rights Reserved $100 Exons and introns are the main parts of these.
  65. 65. © Mark E. Damon - All Rights Reserved $100 What are genes? Scores
  66. 66. © Mark E. Damon - All Rights Reserved $200 A term for all of the genes and associated DNA found in human cells.
  67. 67. © Mark E. Damon - All Rights Reserved $200 What is the human genome? Scores
  68. 68. © Mark E. Damon - All Rights Reserved $300 A laboratory method used to visualize the results of a PCR reaction.
  69. 69. © Mark E. Damon - All Rights Reserved $300 What is gel electrophoresis? Scores
  70. 70. © Mark E. Damon - All Rights Reserved $400 One quarter of our DNA comes from each of these relatives.
  71. 71. © Mark E. Damon - All Rights Reserved $400 Who are our grandparents? Scores
  72. 72. © Mark E. Damon - All Rights Reserved $500 A genetics professional responsible for providing information on inherited disorders, assessing risk, and interpreting genetics test results.
  73. 73. © Mark E. Damon - All Rights Reserved $500 Who is a genetic counselor? Scores
  74. 74. © Mark E. Damon - All Rights Reserved $100
  75. 75. © Mark E. Damon - All Rights Reserved $100 What is a karyotype? Scores
  76. 76. © Mark E. Damon - All Rights Reserved $200
  77. 77. © Mark E. Damon - All Rights Reserved $200 What is a pedigree? Scores
  78. 78. © Mark E. Damon - All Rights Reserved $300
  79. 79. © Mark E. Damon - All Rights Reserved $300 What is amniocentesis? Scores
  80. 80. © Mark E. Damon - All Rights Reserved $400
  81. 81. © Mark E. Damon - All Rights Reserved $400 What is SKY? Scores
  82. 82. © Mark E. Damon - All Rights Reserved $500
  83. 83. © Mark E. Damon - All Rights Reserved $500 Who are Watson and Crick? Scores
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