Hiv natural origin drugs
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Hiv natural origin drugs Hiv natural origin drugs Presentation Transcript

  • NATURAL TREATMENT FOR AIDS
    Presented by
    Vedasree Reddy.Police
    10T21SO112
    Under
    the Guidance of
    Mrs.SharadhaSrikanth
    M.Pharm
  • Contents:
    Types
    What does AIDS means
    Definition of Immunodeficiency Disorders
    Etiological Agent
    Structure of HIV
    Steps of progression
    Diagnosis
    List of Natural Drugs
    Immune Boosters
    New Discoveries and updates
  • ImmunoDeficiencyDisorder:
    Failure or deficiency of immune system which manifests by occurrence of repeated infections in individuals with immune deficiency diseases.
  • Types:
    • Primary _ Genetic or Developmental abnormalities of immune system
    Ex:Reticular dysgenesis
    • Secondary – Acquired Supression of Immunesystem.
    Ex:AIDS,Infections.
  • AIDS MEANs:
    • Acquired Immuno Deficiency Syndrome
    • An epidemic,transmissible retroviral disease caused by infection with HIV which leads to profound depression of cell mediated immunity.
  • ETIOLOGICAL AGENT:
    • HIV- Human Immuno Deficiency Virus.
    • 2 forms:HIV-1
    • HIV-2
    • A RNA retrovirus.
  • STRUCTURE OF HIV
  • STEPS OF PROGRESSION:
  • DIAGNOSIS:
    • 1.For establising HIV infection:
    a.Antibody Test – ELISA
    Western blot
    b.Direct Detection of HIV
    • 2.Tests for Defects in Immunity
    • 3.Tests for Detection of opportunistic infections
  • Natural drugs
    • BITTERMELON
    • LICORICE
    • ECHINACEA
    • CAT’S CLAW
  • BITTERMELON:Friutsof Momordicacharantia.FAMILY: Cucurbitaceae.
  • Mechanism:
    Proteins-
    • MRK29, may inhibit the activity of HIV-1 reverse transcriptase, an enzyme involved in the replication of the HIV virus.
    • MAP30, which may have anti-HIV effects and that may also improve the efficacy of other anti-viral drugs.
  • Considerations:
    • Short-term use of bitter melon is likely safe, but using it for more than three months may be unsafe.
    • Avoid in bleeding disorder
    • Pregnant or breastfeeding women.
    • Glucose-6-phosphate dehydrogenase deficiency people.
  • Licorice:Licorice root  is the root of plant Glycyrrhizaglabra of family Leguminosae.
  • Mechanism :
    • Glycyrrhizin inhibits HIV replication by
    1.Inhibiting a cellular enzyme(Casein Kinase )
    2.Inhibiting viral adsorption, i.e,binding to the host cell to be infected .
  • Considerations:
    • Pseudoaldosteronism.
    • Pregnant or breastfeeding women should not take licorice.
    • Use of any licorice product is not recommended for longer than 4 - 6 weeks.
     
  • ECHINACEA: flowering plant of genus purpurea of family astraceae.
  • Mechanism:
    • Fat soluble Alkylamides of the flower provide Immunomodulatory effects which act by binding to cannabinoid receptors and thus inhibits tumour necrosis factor-α
  • Considerations:
    • One dose treatment is not effective.
    • Allergic reactions like asthma attack and leucopenia are seen.
    • Use along with hepatotoxic drugs is avoided.
    • Avoided in patients with autoimmune disorders
  • CAT’S CLAW: Climbing stems of Uncaria tomentosa of family Rubiaceae.
  • Mechanism :
    • Quinovic acid has a property of
    • Pronounced enhancement effect on PHAGOCYTOSIS.
    • Increased production of T-lymphocytes.
  • Consideration:
    • Because of abortive effects, it is avoided in pregnant women.
    • Dizziness and Vomiting are seen.
  • immune boosters:
    • Aloe Vera
    • Astragalus
    • Ginkgo
    • Ginger
    • Garlic
    • Olive leaf extract
    • Calendula
    • Green tea
  • New discoveries and updates
  • Conclusion:
    • The remedy for all is –
    “PREVENTION IS BETTER THAN CURE”
    This holds good particularly in case of AIDS as it is a preventable disease.
    Leading a healthy and educative lifestyle can do better with respective AIDS.
    Natural remedy need not be necessarily be a cure but can be an alternative or more preferably a preventive in the case of AIDS.