Az 1924/2006/EK rendelet szerint élelmiszereknek gyógyhatás nem tulajdonítható!Disclaimer: MentalFitol™ products are not intended to diagnose, treat, cure or prevent any disease.
Pharmacoidea Ltd. The Company: a biotech SME founded in 2006 Szeged Hungary 2006, Szeged, CEO: Tamas Letoha, MD, PhD Mission: To bring safe and innovative therapeutics against diseases with unmet medical needs• Team: selected from forward thinking scientists interested to translate basic science results rapidly into innovative therapeutics therapeutics, incorporating high added value by rational drug design and food engineering• Laboratory: based at the Biological Research Center of the Hungarian Academy of Sciences (www.brc.hu)
„Let food be thy medicine” medicine” Major change in consumer’s demands: optimal diet can prevent 25-70% of lifestyle-related diseases → awareness of the benefits of healthy eating Development of value-added functional food products p p – the global market of functional food industry will reach 176.7 billion USD in 2013 with a compound annual growth rate of 7 4%7.4% – developed with scientific tools of the 21st century, food products capable of specific elimination of causative targets of endemic diseases will conquer international food markets
Protein aggregation diseases– Degenerative diseases based on pathological aggregation of misfolded proteins • Alzheimers disease ( 10% prevalence at the age of 65 years Alzheimer s and 50% at the age of 85 or above) • Parkinsons disease ( 0.37% of the whole population ) • Type II diabetes (150 million cases worldwide in 2002 ) • Age-related macular degeneration ( 2% of the population g g p p aged 50 and 30% of the population aged 75 years or more )– Common molecular pattern– Presently incurable, prevention is the only option– Aim: development of functional food products containing scientifically validated agents
Protein aggregates (plaques) β-amyloid ( (Alzheimer) ) α-synuclein (Parkinson) amylin(Type II Diabetes) drusen (AMD) ( )
Plaque depositionBrain → Alzheimer Parkinson Alzheimer,Pancreas → Type II DiabetesEye (retina) → AMD Plaque in the brain Plaque deposition -> neuronal death -> dementia
Plaque Busters q High-throughput bioassays + transgenic animal models +in silico modeling and docking algorithms + structure-activity relationships structure activity a molecular library of new chemical entities l l lib f h i l titi – like thorough molecular lancets, plaque busters can specifically recognize and eliminate pathological protein aggregates/plaques (see figure below)Healthy brain Alzheimer brain Alzheimer brain + Plaque Busters
MentalFitol™ MentalFitol Molecular biology/pharmacology + bioinformatics + clinics A mix of health preserving botanical agents developed with state-of-the-art drug p g discovery approaches Compounds has been validated from bench to bedside clinical studies in Alzheimer’s disease (Disclaimer: MentalFitol™ food products are not intended to diagnose, treat, cure or prevent any disease.)
MentalFitol™ food family MentalFitol Great variety from the internationally acknowledged Co’s Co s of the PharmacoFood Cluster (~1 billion € turnover/year) Bakery, pastry, dairy, meat products, matzo, pasta, pizza, sauces, vega food etc. g MentalFitol™ functional food products offer the pleasure of eating while delivering scientifically validated health health- preserving bioactive compounds, thus contributing to the improvement of life quality f l i t f lif lit for large costumer populations t l ti ,,, (Disclaimer: MentalFitol™ food products are not intended to diagnose, treat, cure or prevent any disease.)
”One Bite Fits All!” One All!sausages ready-made meat matzo pasta
ContactTamás Letoha, MD, PhD á Chief Executive Officer (CEO)Address: Körös sor 50, 6753 Szeged, HungaryPhone: +36(30)257-7393E-mail: firstname.lastname@example.orgHomepage: www.pharmacoidea.eu o epage p a aco dea eu
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