TexRAD Pulmonary Cancer

Pulmonary Disorders 1 Pulmonary Disorders Clinical Evidence – Investigative Radiology 2008 [1] 5 6 6 7 8 3D volume rendered coronal, left and right sagittal views of (A) airway lung (fine) texture, (B) vascular lung (coarse) texture, and (C) the fusion of airway and vascular lung texture (intensity- and gradient-based) in a patient with no pulmonary disorders. 1 2 3 4

Pulmonary Disorders 2 Pulmonary Disorders Clinical Evidence – Investigative Radiology 2008 [1] 5 6 6 7 8 3D volume rendered coronal, left and right sagittal views of (A) airway lung (fine) texture, (B) vascular lung (coarse) texture, and (C) the fusion of airway and vascular lung texture (intensity- and gradient-based) in a patient with only pulmonary embolism. 1 2 3 4

Pulmonary Disorders 3 Pulmonary Disorders Clinical Evidence – Investigative Radiology 2008 [1] 5 6 6 7 8 3D volume rendered coronal, left and right sagittal views of (A) airway lung (fine) texture, (B) vascular lung (coarse) texture, and (C) the fusion of airway and vascular lung texture (intensity- and gradient-based) in a patient with pulmonary embolism and emphysema. 1 2 3 4

Pulmonary Disorders 4 Pulmonary Disorders Clinical Evidence – Investigative Radiology 2008 [1] The best distinction between emphysematous and non-emphysematous lung was observed for filtered fine airway texture quantified as MGI The best distinction between normal and patients with pulmonary disorders was observed for filtered coarse vascular texture quantified as entropy and uniformity A progressive percentage change from normal was observed for coarse vascular texture within PE and emphysematous lung Airway and vascular texture metrics demonstrated postural gradient consistent with known physiology 5 6 6 7 8 1 2 3 4

References - Pulmonary

PULMONARY DISORDER

1. Ganeshan B, Miles KA, Young RCD, Chatwin CR. Three-dimensional selective-scale texture analysis of computed tomography pulmonary angiograms. Invest Radiol. 2008; 43(6):382-94.