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Odontogenesis Odontogenesis Presentation Transcript

  • ODONTOGENESISDr. Brian E. Esporlas
  • Stages in the life cycle of atooth1. GrowthPhysiologic processa. Initiationb. Prolifirationc. Histodifferentiationd. Morphodifferentiatione. Apposition2. Calcification3. Eruption4. apposition
  • 3 developmental process beforefunction Grow Calcify Erupt Unlike kidney and heart.. Afte growth .. Function Unlike bone… growth and calcify… function
  • Initiation stage 6th weeks intra uterine life: first sign of tooth development Dental lamina: represent the first sign of tooth development. This is the GERMINAL BAND OF EPITHELIUM
  • Function of dental lamina Initiate the development of the whole deciduous dentition Initiate the development of the succedenuous teeth, by proliferation of bud from enamel organ Initiates the development of the accesional teeth from the distal extention of the dental lamina
  • Vestibular lamina After the dental lamina, the vestibular lamina will arise as another ectodermal thickening, but anterior to the dental lamina. Then this will split to form the vestibular groove the future vestibule.
  • Bud stage At certain point on DL representing the location of 10 manibular and 10 maxillary deciduous teeth cells multiply still more rapidly and form a knob like projections oward the mesoderm Down ward growth creating dental sac, dental papila and dental organ For the mandibular anterior 6th to 7 weeks Max anterior 7th to 7 ½ week Deciduous molars 8th week
  • Cap stage The epithelial bud will continue to proliferate and expand latrally Defferent part of the bud will show unequal growth leading to the formation of a cap stage dental organ( with invagination)
  • 3 layers of cap stage Outer dental epithelium Inner dental epithelium Stellate reticullum (enamel pulp, Filled with mucoid fluid rich in albumin)Star shape cell During late cap stage Stratum intermedium : flat cell between inner dental epithelium and stalate reticulum.
  •  Enamel knot: bud like enlargement , germinal center for the demand of cell growth of tooth Enamel cord: vertical extension of the enamel knot that maintain the cap shape dental organ Enamel naval: attachment of enamel cord to outer dental epithelium
  • Bell stage .Dental lamina 2.Dental sac or follicle 3.Outer dental epithelium 4.Stellate reticulum 5.Inner dental epithelium 6.Dental papilla 7.Enamel cord 8.Enamel navel 9.Blood vessel 10.Enamel niche 11.Successional dental lamina
  • Dental papilla The invaginated part of the dental organ is occupied by condensation of mesenchymal tissues. Peripheral cells ( cuboidal – columnar) differentiates into odontoblast through the stimulation of the cell of the IEE ODONTOBLAST – formtive cell of dentin Central part will be the pulp
  • Membrana preformativa Former basement membrane (separating the dental papilla from the IDE FUTURE dentino enamel junction
  • Tooth germ and dental sac During bell stage, the mesodermal tissue arround the enamel orgarn and the dental papilla differentiates into connective tissue capsule, dental sac. As a resulth 3 tooth germs are developed.a. Dental organ – will give rise to enamel tissueb. Dental papilla – give rise to dentin and pulpc. Dental sac – give rise to cementum, pdl and alveolar bone.
  • Dental organ Give rise to enamel Play an active role in the formation of dentin Play a role in formation of root via HERS or hertwig’s epithelial root sheath. (from the junction of the IDE and ODE) Produces enamel cuticle: last product of ameloblast Remain as epithelial attachment of the neck of the toth after the tooth has erupted
  • histodifferentiation Peripheral cells of the inner dental epithelium differentiates into ameloblast (formative cells of enamel) With the influence of the ameloblast, the formative layer of dentin known as the ODONTOBLAST are formed from the cells of the periphery of the dental papill
  • Morphodifferentiation The shape and form of the crown is determine by the membrana preformativa
  • Fate of dental lamina The remnant should be calcified and be resorbed by osteoclast because it has no function But, some group of epithelial cells may persist to stay (called gland of serres) and differentiates into ENAMEL MASS, SUPERNUMERARY TEETH, TUMORS OR CYST ( ameloblastoma)