Appetite stimulant and

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Appetite stimulant and

  1. 2. Energy intake > Energy expenditure stored as adipose Appetite Satiety Absorption Metabolic rate Thermogenesis Physical action
  2. 3. Genetic Factors Energy expenditure ↓ Environmental Factors Energy intake ↑ Neuroendocrine regulation OBESITY <ul><li>Psycological aspect </li></ul><ul><li>Cultural & Socioeconomic aspects </li></ul><ul><li>Hormones </li></ul><ul><li>Neurotransmitter </li></ul><ul><li>Enzymes </li></ul><ul><li>Receptors </li></ul><ul><li>Total caloric content </li></ul><ul><li>Composition of the diet </li></ul><ul><li>Resting metabolic rate </li></ul><ul><li>Thermo genesis </li></ul><ul><li>Physical activity </li></ul>
  3. 5. Central NPY Cocaine Agouti related peptide Amphetamine Dopamine Histamine Noradrenaline Peripheral Gherlin Leptin Dynorphin Insulin

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