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  • Hi. My name is David and I’m going to tell you about RxFx.
  • RxFx aims to provide people with recommendations that are personally tailored to the side effects they are most wanting to avoid.
  • Transcript

    • 1. RxFx David J. Paulsen
    • 2. We all have different needs.
    • 3. Finding the right Rx is costly in terms of both time and comfort.
    • 4. RxFx
    • 5. Data Source • openFDA database: – 3 million records self- or physician-reported entries from around the world – more than 320k drug listings – 16k side effect listings – 6.1 million side effects by indication – 13k indications (e.g. depression)
    • 6. Data Cleaning – reduced ~320k drug listings to ~90k • grep & python pattern replacement, n-gram similarity – reduced openFDA data set to tables listing the proportion of patients experiencing • side effect f with drug x for indication y. where ϖ = inverse of rank ordering preferences 1-k and ρi,k = probabilities of side effects 1-k for drug i Recommendation =
    • 7. David J. Paulsen Development of Risky Decision Making Duke University Center for Cognitive Neuroscience University of Pittsburgh Medical Center

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