RxFx
David J. Paulsen
We all have different needs.
Finding the right Rx is costly in terms
of both time and comfort.
RxFx
Data Source
• openFDA database:
– 3 million records self- or physician-reported
entries from around the world
– more than ...
Data Cleaning
– reduced ~320k drug listings to ~90k
• grep & python pattern replacement, n-gram similarity
– reduced openF...
David J. Paulsen
Development of
Risky Decision Making
Duke University
Center for Cognitive
Neuroscience
University of Pitt...
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  • Hi. My name is David and I’m going to tell you about RxFx.
  • RxFx aims to provide people with recommendations that are personally tailored to the side effects they are most wanting to avoid.
  • Slides

    1. 1. RxFx David J. Paulsen
    2. 2. We all have different needs.
    3. 3. Finding the right Rx is costly in terms of both time and comfort.
    4. 4. RxFx
    5. 5. Data Source • openFDA database: – 3 million records self- or physician-reported entries from around the world – more than 320k drug listings – 16k side effect listings – 6.1 million side effects by indication – 13k indications (e.g. depression)
    6. 6. Data Cleaning – reduced ~320k drug listings to ~90k • grep & python pattern replacement, n-gram similarity – reduced openFDA data set to tables listing the proportion of patients experiencing • side effect f with drug x for indication y. where ϖ = inverse of rank ordering preferences 1-k and ρi,k = probabilities of side effects 1-k for drug i Recommendation =
    7. 7. David J. Paulsen Development of Risky Decision Making Duke University Center for Cognitive Neuroscience University of Pittsburgh Medical Center

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