CV_Cook Ian.doc

Cook IJ Updated 07/07/2010 CURRICULUM VITAE IAN JAMES SYDNEY COOKPERSONAL DETAILSDate of Birth: 1st May 1954Nationality: AustralianPRESENT APPOINTMENTS1990 - Senior Staff Specialist in Gastroenterology, Director, Gastrointestinal Motility Service and the St George Swallow Centre The St. George Hospital, Sydney2003 - Professor of Medicine (Conjoint) University of New South WalesAddress: Gastroenterology Department Level 1, Burt Wing St. George Hospital, Kogarah, Sydney, AUSTRALIA 2217 Telephone: +61 2 9113 2817 (work) +61 2 9967 8429 (home) Facsimile: +61 2 9113 3993 Email: I.Cook@unsw.edu.auEDUCATION1960 - 1971 The Scots College, Sydney1972 - 1977 University of Sydney Medical School1981 - 1985 Royal Australasian College of Physicians Trainee in Internal Medicine and GastroenterologyDEGREES AND PROFESSIONAL QUALIFICATIONS1978 MB.BS. (Hons) University of Sydney1985 FRACP (Royal Australasian College of Physicians)1989 MD (University of Sydney) 1

Cook IJ Updated 07/07/2010PROFESSIONAL REGISTRATIONS1978 - NSW Medical Board, (MPO116816)1986 Visa Qualifying Examination, USA1987 - Medical Board, State of Wisconsin, USA (29043-020)PREVIOUS APPOINTMENTS1978 - 1980 Resident Medical Officer Sydney Hospital1981 Gastroenterology Registrar Royal Prince Alfred Hospital, Sydney1982 Gastroenterology Registrar St. George Hospital, Sydney1983 Registrar in Internal Medicine and Cardiology Repatriation General Hospital, Concord, Sydney1984 Gastroenterology Registrar Repatriation General Hospital, Concord, Sydney1985 - 1987 Research Fellow in Gastroenterology McMaster University Medical Centre, Canada1987-1988 Research Fellow, Depts. Radiology and Gastroenterology Medical College of Wisconsin, USA1988 – 1990 Gwendolyn Michell Senior Research Fellow Department of Medicine, University of Adelaide1988 - 1990 Visiting Consultant Gastroenterologist Royal Adelaide Hospital1990 - 1995 Senior Lecturer in Medicine (Conjoint) University of New South Wales1996 - 2003 Associate Professor of Medicine University of New South Wales2003 - Professor of Medicine (Conjoint) University of New South Wales 2

Cook IJ Updated 07/07/2010MEMBERSHIP OF LEARNED SOCIETIES1986 - Gastroenterological Society of Australia1989 - American Gastroenterological Association1990 - 1999 American Motility Society1990 - 2000 Functional Brain-Gut Research Group1991 - International Society for Diseases of the Esophagus1997 - Dysphagia Research Society2002 - O.E.S.O. (Permanent Scientific Committee)COMMITTEES AND BOARDS1988 - 1990 Honorary Secretary, Department of Medicine Committee University of Adelaide1989 - 1990 Convenor, Symposium on Dysphagia, World Congress of Gastroenterology, Sydney, 19901989 - 1990 Organising Committee - Symposium, Pharmacotherapy of Gastrointestinal Motility Disorders. Satellite Meeting of World Congress of Gastroenterology Sydney, 19901991 - 1997 Sydney Gut Club Committee1991 - 1993 St George Hospital Annual GI Symposium Committee1991 - Pharyngo-esophageal Research Committee International Society for Diseases of the Esophagus1992 - 1993 Working Party; preparation patient and GP information booklets (Reflux disease; irritable bowel syndrome). Australian Gastroenterology Institute.1992 - 1994 Organising Committee Australian Gastroenterology Week, Sydney, Gastroenterological Society of Australia1993 - 1995 Chairman, Organising Committee, Clinical Update Meeting, Leura, Gastroenterological Society of Australia1993 - 1996 Scientific Programme Committee, Gastroenterological Society of Australia 3

Cook IJ Updated 07/07/20101993 - 1998 Organising Committee, International Motility Conference, Lorne, International Motility Society.1994 - 1997 NSW Motility Society Organising Committee1996 - 1998 Synergies Committee, St George Hospital.1997 - Medical Appointments Advisory Committee, St George Hospital.1997 Strategic planning committee workshop. Gastroenterological Society of Australia1997 - 1998 Chairman, International Working Party on Intestinal Pressure Wave Analysis, International Motility Society1997 - 1998 Co-chairman, Scientific Program Committee, Dysphagia Research Society1997 - 1998 Scientific Program Committee, Dysphagia Research Society1998 - 2000 Governing Board Member, Dysphagia Research Society2001 Secretary-Treasurer, Dysphagia Research Society2001- 2002 Expert Reference Group; Division of Strategic Policy and Planning, Department of Ageing Disability and Home Care, NSW Health (Informed decision making project for carers and people with special nutritional needs and swallowing problems).2003 - 2004 President, Dysphagia Research Society2003 Chairman, Scientific Program Committee, Dysphagia Research Society2003 - 2005 Rome III Committee (Multinational working party developing criteria for functional GI disorders)2003 - OESO (Organisation mondiale d’Etudes Spécialisées sur les maladies de l’Oesophage) Permanent Scientific Committee2006 - Greater Metropolitan Clinical Taskforce (GMCT) Gastroenterology Executive Committee2006 - DDW Program Evaluation Subcommittee (International Member), Am Gastroent Association2006 - Member, Board of Trustees, St George Medical Research Foundation2007 - Chair, Scientific Advisory Committee, St George Medical Research Foundation 4

Cook IJ Updated 07/07/20102007 - Member, Scientific Programme Committee, International Society of Neurogastroenterology and Motility2007 - Inaugural Board Member, St George Medical Research Foundation2007 - Chairman, Scientific Advisory Committee, St George Medical Research Foundation2009 - 2010 Steering Committee, 10th World Congress, OESO (Organisation mondiale d’Etudes Spécialisées sur les maladies de l’Oesophage), Boston, 2010.INDUSTRY-RELATED ADVISORY BOARDS & EXPERT PANELS1995 - 2002 Gastroenterology Advisory Board, GlaxoWellcome Australia1999 - 2001 Gastroenterology Advisory Board, GlaxoWellcome, Asia Pacific Region1999 - 2001 Gastroenterology Advisory Board; Janssen Pharmaceuticals, Asia Pacific Region2000 Chairman GlaxoWellcome Asia Pacific Advisory Panel2000 - Gastroenterology Advisory Board, AstraZeneca, Australia2000 - 2002 Gastroenterology Advisory Board; Janssen Pharmaceuticals, Australia2000 - 2003 Gastroenterology Advisory Panel, Novartis, AustraliaAWARDS AND DISTINCTIONSUndergraduate1977 Carnation Paediatric Prize, University of Sydney1977 Robert Craig Prize in Surgery, University of SydneyPostgraduate1985 - 1987 University of Sydney Postgraduate Committee in Medicine Medical Foundation Award1985 - 1987 University of Sydney Ethel and Mary Thomas Ewing Scholarship in Medicine1985 Sydney Hospital Norman Rose Travelling Fellowship 5

Cook IJ Updated 07/07/20101985 McMaster University, Ontario Regional Medical Associates Scholarship1988 - 1990 University of Adelaide Gwendolyn Michell Senior Research Fellowship1989 Gastroenterological Society of Australia Young Investigator Award (best research paper, GE Society Scientific Meeting)1989 Glaxo Educational Travel Grant for excellence in research2010 American Gastroenterological Association Masters Award for Outstanding Achievement in Basic or Clinical Digestive SciencesTEACHING EXPERIENCE1985 - 1987 Clinical Tutor, Department of Medicine McMaster University, Canada1988 - 1990 Clinical Tutor and Lecturer, Department of Medicine University of Adelaide1991 - Senior Lecturer (1991-1995), and A/Prof & Prof in Medicine (1996 - ) University of New South WalesPOSTGRADUATE PROGRAMMES1985 McMaster University Postgraduate Program Department of Epidemiology and Biostatistics. Courses in Clinical Epidemiology (MS 721) and Biostatistics (MS 702) in Design, Measurement and Evaluation Program.SERVICES TO MEDICAL JOURNALS1990 - Editorial Board: Dysphagia1995 - 1996 Acting, honorary subeditor, Aust NZ J Med2001- 2003 Editorial Board, Current Therapeutics2005 - 2007 Editorial Board, Neurogastroenterology and Motility 6

Cook IJ Updated 07/07/2010Reviewer for: Alimentary Pharmacology and Therapeutics American Journal of Gastroenterology American Journal of Physiology Australian and New Zealand Journal of Medicine Current Opinion in Gastroenterology Clinical Gastroenterology and Hepatology Dysphagia Digestive Diseases and Sciences Digestion European Journal Gastroenterology and Hepatology Gastroenterology Gut Journal of Gastroenterology and Hepatology Medical Journal of Australia Nature Clinical Practice Gastroenterology & Hepatology Neurogastroenterology and Motility Scandinavian Journal of GastroenterologySUPERVISION OF POSTGRADUATE STUDENTS/FELLOWSPostdoctoral1989 - 1991 Dr. Yoshi Furukawa, Dept. of Surgery, Jikei University, Tokyo1990 - 1991 Dr. Folke Johnsson (Florey Research Fellow, Royal Adelaide Hospital), Dept. of Surgery, Lund University, SwedenPostgraduate (Higher Degree Students)1989 - 1991 Dr. David Shaw (MD student), NH&MRC Postgraduate Scholar1992 - 1994 Dr. Galib Ali (MD awarded 1998), NH&MRC Postgraduate Scholar1995 - 1998 Ms Karen Wallace (MSc awarded April 2001)1995 - 2002 Mr Rohan Williams (MSc converted to PhD; awarded, April 20031996 - 1998 Dr Peter Bampton (MD awarded Dec 2002), NH&MRC Postgraduate Scholar1999 - 2005 Dr Philip Dinning (PhD awarded, Sept 2005)2003 - 2008 Mr Michal Szczesniak (PhD awarded, 2008)2006 - 2009 Dr Harry Chen (PhD awarded 2009)2005 - 2010 Ms Julia MacLean (Co-superviser; PhD submitted 2010)SUPERVISION OF OTHER RESEARCH PERSONNELPostgraduate1995 - 1996 Dr. Tetsuya Kajimoto (Glaxo Gastroenterology Fellow, St George Hospital), Dept. of Surgery, Jikei University, Tokyo2001 Dr Annie Ng, Dept Medicine, St Anne’s, Hong Kong 7

Cook IJ Updated 07/07/2010Research Assistants1988 - 1991 Ms Voula Panagopoulos BSc (Hons)1989 - 1990 Ms Maria Simula BSc (Hons)1991 - 1998 Ms Karen Wallace BSc1992 - 1994 Ms Tina Laundl BSc (Hons)1994 - 1998 Mr Philip Dinning BSc (Hons)1994 - 2002 Mr Rohan Williams BAppSc1994 - 1995 Ms Jenny Phillips RN1995 - 1996 Ms Adrienne Dorian RN1996 - 1997 Ms Elizabeth Donohoo BSc1997 - 1998 Ms Rebecca Jennings BSc1998 - 1998 Ms Connie To BSc1998 - 2000 Ms Julie André BA (Hons) Social Sc2000 - 2001 Ms Tatiana Sourjina Degree in Preventative Medicine (St Petersburg)2001 - 2003 Mr Michael Szczesniak BSc (Hons)2002 - 2003 Ms Anthea Burnett (BSc)2003 - Mr Sergio Fuentealba (BSc)2008 - Ms Linda Hunt (BSc) 8

Cook IJ Updated 07/07/2010ORIGINAL PEER REVIEWED PUBLICATIONS 1. Shulkes A, Boden R, Cook I, Gallagher N, Furness J. Characterization of a pancreatic tumour containing vasoactive intestinal peptide, neurotensin and pancreatic polypeptide. J Clin Endocrinol Metab 1984;58:41-48. 2. Cook IJ, Pavli P, Riley J, Goulston KJ, Dent OF. Gastrointestinal investigation of iron deficiency anaemia. Br Med J 1986;292:1380-1382. 3. Goulston KJ, Cook IJ, Dent OF. How important is rectal bleeding in the diagnosis of bowel cancer and polyps? Lancet 1986;2:261-264. 4. Cook IJ. Determinants of symptoms in the irritable bowel syndrome. Doctoral thesis, University of Sydney, 1987. 5. Cook IJ, Dent J, Shannon S, Collins SM. Measurement of upper esophageal sphincter pressure: effect of acute emotional stress. Gastroenterology 1987;93:526-532. 6. Cook IJ, van Eeden A, Collins SM. Patients with irritable bowel syndrome have greater pain tolerance than normal subjects. Gastroenterology 1987;93:727-733. 7. Cook IJ, Collins SM. The influence of acute mental stress on the frequency and duration of gastroesophageal reflux in normal volunteers. Can J Gastroenterol 1987;1:7-10. 8. Cook IJ, de Carle DJ, Haneman B, Hunt D, Talley NA. The role of brushing cytology in the diagnosis of gastric malignancy? Acta Cytologica 1988;32:461-464. 9. Cook IJ, Reddy SN, Collins SM, Daniel EE. Influence of recording techniques on measurement of canine colonic motility. Dig Dis Sci 1988;32:999-1006. 10. Dodds WJ, Mann KM, Cook IJ, Kahrilas PJ, Stewart ET, Kern MK. Influence of bolus volume on swallow-induced hyoid movement in normal subjects. AJR 1988;150:1307-1309. 11. Shaker R, Cook IJ, Dodds WJ, Hogan WJ. Pressure-flow dynamics of the oral phase of swallowing. Dysphagia 1988;3:79-84. 12. Cook IJ, Dent J, Collins SM. Upper esophageal sphincter tone and reactivity to stress in patients with a history of globus sensation. Dig Dis Sci 1989;34:672-676. 13. Shannon S, Hollingsworth J, Cook I, Collins SM. The effect of Trimebutine on postprandial colonic motor activity in healthy subjects and patients with the irritable bowel syndrome. J Gastroint Motility 1989;1:9-14. 14. Mant A, Bokey EL, Chapuis PH, Killingback M, Hughes W, Koorey SG, Cook IJ, Goulston KJ, Dent OF. Rectal bleeding - Do other symptoms aid in diagnosis? Dis Colon Rectum 1989;32:191-196. 15. Cook IJ, Dodds WJ, Dantas RO, Massey B, Kern MK, Lang JM, Brasseur JG, Hogan WJ. Opening mechanisms of the human upper esophageal sphincter. Am J Physiol 1989;257:G748-G759. 9

Cook IJ Updated 07/07/201016. Cook IJ, Dodds WJ, Dantas RO, Kern MK, Massey BT, Shaker R, Hogan WJ. Timing of videofluoroscopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing. Dysphagia 1989;4:8-15.17. Dodds WJ, Taylor AJ, Stewart ET, Kern MK, Logemann JA, Cook IJ. Tipper and dipper types of oral swallows. AJR 1989;153:1197-1199.18. Cook IJ, Irvine EJ, Campbell D, Shannon S, Reddy SN, Collins SM. Effect of dietary fibre on symptoms and rectosigmoid motility in patients with irritable bowel syndrome: a controlled crossover study. Gastroenterology 1990;98:66-72.19. Dantas RO, Dodds WJ, Massey BT, Shaker R, Cook IJ. Manometric characteristics of glossopalatal sphincter. Dig Dis Sci 1990;35:161-166.20. Dantas RO, Kern MK, Massey BT, Dodds WJ, Kahrilas PJ, Brasseur JG, Cook IJ, Lang IM. Effect of swallowed bolus variables on oral and pharyngeal phases of swallowing. Am J Physiol 1990;258:G675-G681.21. Dantas RO, Cook IJ, Dodds WJ, Kern MK, Lang IM, Brasseur JG. Biomechanics of cricopharyngeal bars. Gastroenterology 1990;99:1269-1274.22. Cook IJ, Jamieson G, Blumbergs P, Shaw D, Dent J. Pathogenie et traitment du diverticule de Zenker. Chirurgie 1990; 116:673-678.23. Lang IM, Dantas RO, Cook IJ, Dodds WJ. Videoradiographic, manometric, and electromyographic analysis of canine upper esophageal sphincter. Am J Physiol 1991;260: G911-G919.24. Cook IJ, Gabb M, Panagopoulos V, Jamieson GG, Dodds WJ, Dent J, Shearman DJ. Pharyngeal (Zenkers) diverticulum is a disorder of upper esophageal sphincter opening. Gastroenterology 1992;103:1229-1235.25. Cook IJ, Blumbergs P, Cash K, Jamieson GG, Shearman DJ. Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenkers) diverticulum. J Gastroenterol Hepatol 1992;7:556-562.26. Cook IJ, Dent J, Collins SM. Influence of caloric labyrinthine stimulation on esophageal motor function. J Gastroint Motility 1993;5:137-141.27. Willing J, Davidson GP, Dent J, Cook IJ. Effect of gastro-oesophageal reflux on upper oesophageal sphincter motility in children. Gut 1993;34:904-910.28. Cook IJ, Weltman MD, Wallace K, Shaw DW, McKay E, Smart RC, Butler SP. Influence of aging on oral-pharyngeal bolus transit and clearance during swallowing: scintigraphic study. Am J Physiol 1994; 266:G972-G977.29. Ali GN, Laundl TM, Wallace KL, Shaw DW, deCarle DJ, Cook IJ. Influence of mucosal receptors on deglutitive regulation of pharyngeal and upper esophageal sphincter function. Am J Physiol 1994; 267; G644-G649. 1 0

Cook IJ Updated 07/07/201030. Furukawa Y, Cook IJ, Panagopoulos V, McEvoy RD, Sharp DJ, Simula M. Relationship between sleep patterns and human colonic motor patterns. Gastroenterology 1994; 107:1372-1381.31. Shaw DW, Cook IJ, Gabb M, Holloway RH, Simula ME, Panagopoulos V, Dent J. Influence of normal aging on oral-pharyngeal and upper esophageal sphincter function during swallowing. Am J Physiol 1995; 268:G389-G396.32. Ali GN, Hunt DR, J Jorgensen, deCarle DJ, Cook IJ. Esophageal achalasia and coexistent upper esophageal sphincter relaxation disorder presenting with airway obstruction. Gastroenterology 1995; 109:1328-1332.33. Ali GN, Wallace KL, Zagami A, deCarle DJ, Cook IJ. Mechanisms of oral-pharyngeal dysphagia in Parkinson’s disease. Gastroenterology 1996; 110(2): 383-392.34. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. Influence of cold stimulation on the normal pharyngeal swallow response. Dysphagia 1996;11:2-8.35. Johnsson F, Shaw D, Gabb M, Dent J, Cook I. Influence of gravity and body position on normal oropharyngeal swallowing. Am J Physiol 1995; 269 (5 pt 1):G653-G658.36. Shaw DW, Cook IJ, Jamieson GG, Gabb M, Simula ME, Dent J. Influence of surgery on deglutitive upper oesophageal sphincter mechanics in Zenkers diverticulum. Gut 1996;38:806-811.37. Clark W, Cook IJ. Spontaneous intramural haematoma of the oesophagus: Radiologic recognition. Australasian Radiology 1996;40(3):269-272.38. Ali GN, Wallace KL, Laundl TM, Hunt DR., de Carle DJ, Cook IJ. Predictors of outcome following cricopharyngeal disruption for pharyngeal dysphagia. Dysphagia 1997;12(3):133-139.39. Ali GN, Cook IJ, Laundl TM, Wallace KL, de Carle DJ. Influence of altered tongue contour and position on deglutitive pharyngeal and UES function. Am J Physiol 1997;273:G1071- G1076.40. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. Basal pressure patterns and reflexive motor responses in the human ileocolonic junction. Am J Physiol 1999;276:G331-G340.41. Williams RB, Ali GN, Wallace KL, Wilson JS, deCarle DJ, Cook IJ Esophagopharyngeal acid regurgitation: Dual pH monitoring criteria for its detection and insights into mechanisms. Gastroenterology 1999;117:1051-1061.42. Williams RB, Ali GN, Hunt DR, Wallace KL, Cook IJ. Cricopharyngeal myotomy does not increase the risk of esophagopharyngeal acid regurgitation. Am J Gastroenterology 1999;94(12):3448-3454.43. Dinning PG, Bampton PA, Kennedy ML, Cook IJ. Relationship between terminal ileal 1 1

Cook IJ Updated 07/07/2010 pressure waves and propagating proximal colonic pressure waves. Am J Physiol. 1999; 277(40): G983-G992.44. Kajimoto T, Dinning, PG, Gibb DB, deCarle DJ, Cook IJ. Neurogenic pathways mediating ascending and descending reflexes at the porcine ileocolonic junction. Neurogastroenterology and Motility 2000; 12:125-134.45. Cook IJ, Furukawa Y, Panagopoulos V, Collins PJ, Dent J. Relationships between spatial patterns of colonic pressure and individual movements of content. Am J Physiol 2000;278:G329 – G341.46. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Spatial and temporal organization of pressure patterns throughout the unprepared colon during spontaneous defaecation. Am J Gastroenterol 2000;95(4):1027-1035.47. Wallace KW, Middleton S, Cook IJ. Development and validation of a self-report symptom inventory to assess the severity of oral-pharyngeal dysphagia. Gastroenterology 2000;118:678-687.48. Hunt DR, Wills VL, Weiss B, Jorgensen JO, de Carle DJ, Cook IJ. Management of esophageal perforation after pneumatic dilatation for achalasia. Journal Gastrointestinal Surgery 2000;4(4):411-415.49. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. Prolonged multi-point recording of colonic manometry in the unprepared human colon – Providing insight into potentially relevant pressure wave parameters. Am J Gastroenterol 2001;96(6):1838-1848.50. Williams RB, Pal A, Brasseur JG, Cook IJ. Space-time pressure structure of the pharyngo- esophageal segment during swallowing. Am J Physiol 2001; 281: G1290-G1300.51. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. The proximal colonic motor response to rectal mechanical and chemical stimulation. Am J Physiol Gastrointest Liver Physiol 2002;282:G443-G449.52. Williams RB, Wallace KL, Ali GN, Cook IJ. Biomechanics of failed deglutitive upper esophageal sphincter relaxation in patients with neurogenic dysphagia. Am J Physiol 2002;283:G16-G26.53. Hui JM, Hunt DR, de Carle DJ, Williams RB, Cook IJ. Esophageal dilatation for post- fundoplication dysphagia: safety, efficacy and predictors of outcome. Am J Gastroenterol 2002; 97(12):2986-2991.54. Williams RB, Grehan MJ, Hersch M, Andre J, Cook IJ. Biomechanics, diagnosis, and treatment outcome of inflammatory myopathy presenting as oropharyngeal dysphagia. Gut 2003;52(4):471-478.55. Shaw DW, Williams RBH, Cook IJ, Wallace KL, Weltman MD, Collins PJ, McKay E, Smart R, Simula ME. Oropharyngeal scintigraphy: a reliable technique for the quantitative evaluation of oral-pharyngeal swallowing. Dysphagia 2004;19(1):36-42. 1 2

Cook IJ Updated 07/07/201056. Pal A, Williams RB, Cook IJ, Brasseur JG. Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow. Am J Physiol 2003; 285:G1037-1048.57. Williams RB, Szczesniak M, Maclean J, Brake HM, Cole IE, Cook IJ. Predictors of outcome in an open label, therapeutic trial of high dose omeprazole in laryngitis. Am J Gastroenterol 2004; 99(5):777-85.58. Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ. Abnormal predefecatory colonic motor patterns define constipation in obstructed defaecation. Gastroenterology 2004; 127:49-58.59. Stanton MP, Hutson JM, Simpson D, Oliver MR, Southwell BR, Dinning PG, Cook IJ, Catto-Smith AG. Colonic manometry via appendicostomy shows reduced frequency, amplitude and length of propagating sequences in children with slow-transit constipation. J Ped Surg 2004;40(7):1138-1145.60. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King D, Cook IJ. Impaired proximal colonic motor response to rectal mechanical and chemical stimulation in obstructed defecation. Dis Col Rectum 2005; 48(9): 1777-1784.61. Logemann JA, Williams RBH, Rademaker A, Pauloski BR, Lazarus CL, Cook IJ. The relationship between observations and measures of oral and pharyngeal residue from videofluorography and scintigraphy. Dysphagia 2005; 20:226-231.62. Dinning PG, Cook IJ. Removal of tonic nitrergic inhibition is a potent stimulus for human colonic propagating sequences. Neurogastroenterol Mot 2006; 18: 37-44.63. Omari T, Rommell N, Sczesniak M, Fuentealba S, Dinning P, Davidson, G, Cook IJ. Assessment of intraluminal impedance for the detection of pharyngeal bolus flow during swallowing in healthy adults. Am J Physiol 2006; 290: G183-G188.64. Dinning PG, McKay E, Cook IJ. Validation of a semi-automated scintigraphic technique for detecting episodic, real time, colonic flow. Neurogastroenterol Mot 2006; 18: 547-555.65. Dinning PG, Fuentealba SE, Kennedy ML, Lubowski DZ, King D, Cook IJ. Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defaecation frequency in patients with slow transit constipation. Colorectal Dis 2007; 9(2): 123-132.66. Lee G, Craig PI, Freiman JS, de Carle DJ, Cook IJ. Intermittent dysphagia for solids associated with a multiringed esophagus: clinical features and response to dilatation. Dysphagia 2007; 22(1): 55-62.67. Dinning PG, Szczesniak, M.M. Cook, IJ. Proximal colonic propagating pressure wave sequences and their relationship with movements of content in the proximal human colon. Neurogastroenterol Motil. 2008 May;20 (5):512-520.68. Szczesniak MM, Rommel N, Dinning P, Fuentealba S, Cook I, Omari T. Optimal criteria for detecting bolus passage across the pharyngo-oesophageal segment during the normal swallow using intraluminal impedance recording. Neurogastroenterol Mot. 2008: 1 3

Cook IJ Updated 07/07/2010 May;20(5):440-447.69. Szczesniak MM, Fuentealba SE, Burnett A, Cook IJ. Differential relaxation and contractile responses of the human upper esophageal sphincter mediated by interplay of mucosal and deep mechanoreceptor activation. Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G982-G988.70. Chen CL, Yi CH, Cook IJ. Differences in oesophageal bolus transit between patients with and without erosive reflux disease. Dig Liver Dis. 2008 May;40(5):348-354.71. Chen CL, Szczesniak MM, Cook IJ. Identification of impaired oesophageal bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia. Neurogastroenterol Motil. 2008;20(9):980-988.72. Chen CL, Szczesniak MM, Cook IJ. Oesophageal bolus transit and clearance by secondary peristalsis in normal individuals. European Journal of Gastroenterology & Hepatology 2008;20(12):1129-1135.73. Dinning PG, Szczesniak MM, Cook IJ. Determinants of postprandial flow across the human ileocecal junction: A combined manometric and scintigraphic study. Neurogastroenterol Motil. 2008 Oct;20(10):1119-26.74. Dinning PG, Szczesniak MM, Cook IJ. Twenty-four hour spatiotemporal pressure mapping of colonic pressure waves provides pathophysiological insight into constipation. Neurogastroenterol Motil. 2008 Sep;20(9):1017-21.75. King S, Catto-Smith AG, Stanton MP, Sutcliffe J, Simpson D, Cook IJ, Dinning PG, Hutson JM, Southwell BR. 24-hour colonic manometry in children with slow transit constipation demonstrates significant reduction in antegrade propagation. Am J Gastroenterol 2008;103:2083-2091.76. Arkwright JW, Blenman NG, Underhill ID, Maunder SA, Szczesniak MM, Dinning PG, Cook IJ. In-vivo demonstration of a high resolution optical fiber manometry catheter for diagnosis of gastrointestinal motility disorders. Optics Express 2009;17(6):4500-4508.77. Chen CL, Szczesniak MM, Cook IJ. Evidence for esophageal visceral hypersensitivity and aberrant symptom referral in patients with globus. Neurogastroenterol Motil 2009;21:1142- e96.78. Dinning PG, Szczesniak MM, Cook IJ. Spatio-temporal analysis reveals aberrant linkage among sequential propagating pressure wave sequences in patients with symptomatically defined obstructed defecation. Neurogastroenterol Motil 2009;21(9):945-e75.79. Arkwright JW, Underhill JW, Maunder SA, Blenman NG, Szczesniak MM, Wiklendt L, Cook IJ, Lubowski DZ, Dinning PG. Design of a high-sensor count fiber optic manometry catheter for in vivo colonic diagnostics. Optics Express 2009;17(25):22423-22431.80. Szczesniak MM, Rommel N, Dinning PG, Fuentealba SE, Cook IJ, Omari T. Intraluminal impedance detects failure of pharyngeal clearance during swallowing: A validation study in adults with dysphagia. Neurogastroenterol Mot. 2009: 21(3):244-52. 1 4

Cook IJ Updated 07/07/2010 81. Dinning PG, Zarate N, Szczesniak MM, Mohammed SD, Preston SR, Fairclough PD, Lunniss PJ, Cook IJ, Scott SM. Bowel preparation affects the amplitude and spatiotemporal organization of colonic propagating sequences. Submitted to Neurogastroenterol Mot. Motility 2010: In press (Accepted 19th Jan 2010). 82. Szczesniak MM, Williams RBH, Brake HM, Maclean JC, Cole IE, Cook IJ. Upregulation of the oesophago-UES relaxation response: a possible pathophysiological mechanism in suspected reflux laryngitis. Neurogastroenterol Mot 2010;22(4):381- 386, e89.ORIGINAL PAPERS IN PREPARATION OR SUBMITTED FOR PUBLICATION 1.Dinning PG, Jones M, Hunt L, Fuentealba S, Kalanter J, King D, Lubowski DZ, Talley NJ,Cook IJ. Cluster analysis identifies a laxative-unresponsive subtype of constipation. (SubmittedNeurogastroent Motil Oct 2009). 2.Dinning PG, Zarate N, Hunt L, Szczesniak MM, Mohammed SD, Preston S, Lubowski DZ,Scott M, Cook IJ. Manometric markers of dysmotility in patients with severe slow transitconstipation. (Submitted to Am J Gastroenterol). 3.Dinning PG, Hunt L. Fuentealba S, Lubowski DZ, Arkwright JA, Cook IJ. Sub-sensory sacralnerve stimulation does not induce colonic propulsive activity.BOOK CHAPTERS 1. Cook IJ. The influence of psychological stress on esophageal motility. In: Bueno L, Collins SM, Junien J. eds. Stress and digestive motility. Paris: John Libbey Eurotext, 1989:71-74. 2. Cook IJ. IBS - irritable mind, irritable gut or both? In: Collins SM, ed. Current issues in the management of irritable bowel syndrome. Montreal: STA Communications, 1989:6-9. 3. Cook IJ. Normal and disordered swallowing: new insights. In: Dent J, ed. Practical issues in gastrointestinal motor disorders. Baillieres Clinical Gastroenterology 1991;5(2):245-267. 4. Ali GN, Cook IJ. Oropharyngeal dysphagia - are there practical means of solving? Treatment? In: Barkin JS, Rogers AI, eds. Difficult decisions in digestive diseases. 2nd ed. St Louis: Mosby, 1994;35-42. 5. Cook IJ. Difficulty swallowing and pain on swallowing. In: Talley N, Martin CJ, eds. Clinical Gastroenterology. Sydney: Maclennan and Petty; 1996;20-36. 6. Cook IJ. Hiccup, sore mouth and bad breath. In: Talley N, Martin CJ, eds. Clinical Gastroenterology. Sydney: Maclennan and Petty; 1996;37-49. 7. Cook IJ. Clinical physiology of colonic motor disorders; constipation, urgency, pain. In Phillips SF, Wingate DL eds. Functional disorders of the gut. London: Churchill Livingstone, 1998;269-297. [ISBN 0-4430-5420-7] 1 5

Cook IJ Updated 07/07/2010 8. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, deCarle DJ, Cook IJ. Progress in the development of a physiological method of colonic manometry. In: Goebell H, Holtmann G, Talley N, eds. Functional Dyspepsia and Irritable Bowel Syndrome. London: Kluwer Academic Publishers, 1998; 119-124. [ISBN 0-7923-8734-1] 9. Cook IJ. Disorders causing oropharyngeal dysphagia. In: Castell DO, Richter J eds. The Esophagus. 3rd ed. Philadelphia: Lippincott Williams and Wilkins, 1999; 165-184. 10. Cook IJ, Brookes, SJ. Motility of the large intestine. In: Feldman M, Friedman LS, and Sleisenger MH. Eds. Sleisenger and Fordtran’s: Gastrointestinal and Liver Disease. 7th Edition. Philadelphia: Saunders, 2002;1679-1692 (ISBN 0-7216-8973-6). 11. Cook IJ. Disorders causing oropharyngeal dysphagia. In: Castell DO, Richter J eds. The Esophagus. 4th ed. Philadelphia: Lippincott Williams and Wilkins, 2004; 196-220 (ISBN 0-7817-4199-8). 12. Cook IJ, Brookes, SJ. Sensory and Motor Function of the Colon. In: Feldman M, Friedman LS, and Brandt LJ, Eds. Sleisenger and Fordtran’s: Gastrointestinal and Liver Disease. 8th Edition. Philadelphia: Saunders; 2006:2111-2126. (ISBN 1-41600245-6). 13. Cook IJ. Difficulty swallowing and pain on swallowing. In: Talley N, Martin CJ, eds. Clinical Gastroenterology. 2nd Edition. Sydney: Churchill Livingstone; 2006:20-35. (ISBN 13:978-0-7295-3774-2). 14. Cook IJ. Hiccup, sore mouth and bad breath. In: Talley N, Martin CJ, eds. Clinical Gastroenterology. 2nd Edition. Sydney: Churchill Livingstone; 2006:36-49. (ISBN 13:978-0-7295-3774-2). 15. Galmiche JP, Clouse RE, Balint A, Cook IJ, Kahrilas PJ, Paterson WG, Smout AJPM. Functional esophageal disorders. In Drossman DA, Corazziari E, Delvaux M, Spiller RC, Talley NJ, Thompson WG, Whitehead WE, eds. Rome III: The functional gastrointestinal disorders. 3rd Edition. Virginia: Degnon Associates, Inc: 2006: 369-418. 16. Cook IJ. Dysphagia and odynophagia. In: Talley NJ, Segal I, Weltman MD, eds Gastroenterology and Hepatology: A clinical handbook. Sydney: Churchill Livingstone; 2007:15-26. (ISBN 978-0-7295-3775-9). 17. Cook IJ, Brookes, SJ, Dinning PG. Sensory and Motor Function of the Colon. In: Feldman M, Friedman LS, and Brandt LJ, Eds. Sleisenger and Fordtran’s: Gastrointestinal and Liver Disease. 9th Edition. Philadelphia: Saunders; 2010:1660-1674. (ISBN: 978-1-4160-6189-2). 18. Cook IJ. Difficulty swallowing and pain on swallowing. In: Talley N ed. Clinical Gastroenterology. 3rd Edition. Sydney: Churchill Livingstone; 2010: In press.INVITED REVIEWS 1 6

Cook IJ Updated 07/07/20101. Cook IJ. Esophageal motor disorders as a cause of dysphagia. Motility 1990;9:11-15.2. Cook IJ. Globus - real or imagined? Gullet 1991;1:68-73.3. Cook IJ. Cricopharyngeal function and dysfunction. Dysphagia 1993;8:244-251.4. Cook IJ. Pharyngeal swallowing mechanisms in health and disease. In: Steadman C, ed. Whats new in Gastroenterology 1993; vol 39.5. Cook IJ. The investigation of dysphagia. Modern Medicine 1994;37(1):46-50.6. Kellow J, Cook IJ, Heap T, Steadman C. Irritable bowel syndrome: Australian Gastroenterology Institute statement. Modern Medicine 1994;37:90-98.7. Cook IJ. Swallowing disorders. Current Therapeutics 1996 (May);81-85.8. Cook IJ. Dysphagia: assessment and treatment. Australian Doctor 1996 (June).9. Cook IJ. Swallowing disorders. New Ethicals 1996;33(12):33-41.10. Cook IJ, de Carle DJ. Gastroesophageal reflux disease: diagnosis. Gastroenterology International 1997;10(3):100-108.11. Cook IJ. Investigative techniques in the assessment of oral-pharyngeal dysphagia. Digestive Diseases 1998;16:125-133.12. Cook IJ, Kahrilas PJ. American Gastroenterological Association medical position statement on management of oropharyngeal dysphagia. Gastroenterology 1999; 116(2):452-454.13. Cook IJ, Kahrilas PJ. American Gastroenterological Association clinical practice guidelines: management of oropharyngeal dysphagia. Gastroenterology 1999;116(2):455-478.14. Cook IJ. Colonic manometry – from research tool to clinical practice. Motility 1999; 47(September) :8-10.15. Cook IJ. Diagnosis and management of cricopharyngeal achalasia and other upper esophageal sphincter opening disorders. Current Gastroenterology Reports 2000;2(3):191-195. (http://dx.doi.org/10.1007/s11894-000-0060-6)16. Cook IJ. Gastro-oesophageal reflux disease management: past, present and future. Australian GI Magazine 2000;17:2-4.17. Cook IJ. Treatment of oropharyngeal dysphagia. Current Treatment Options in Gastroenterology 2003:6 (4): 273-281(ISSN 1092-8472).18. Abeygunasekera S, Cook IJ. Difficult and painful swallowing: a guide for GPs. Medicine Today 2003; 4:33-40.19. Shea-Donohue T, Cook IJ, De Giorgio R, Costa M, Dent J, Grundy D, Sanders KM, 1 7

Cook IJ Updated 07/07/2010 Schemann M, Smith TK, Tonnini M, Brookes SJH. A teaching module on irritable bowel syndrome. Neurogastroenterol Motil 2005: 17 (Suppl.3), 1-22. 20. Costa M, Sanders KM, Schemann M, Smith TK, Cook IJ, de Giorgio R, et al. A teaching module on cellular control of small intestinal motility. Neurogastroenterol Motil 2005;17 Suppl 3:4-19. 21. Shea-Donohue T, Cook IJ, De Giorgio R, Costa M, Dent J, Grundy D, Sanders KM, Schemann M, Smith TK, Tonnini M, Brookes SJH. Education project for pathophysiology of gastrointestinal motility. Neurogastroenterol Motil 2005: 17 (Suppl.3), 1-2. 22. Cook IJ. Biomechanics of the upper esophageal sphincter (UES) – does it influence current management? Otologia Fukuoka 2006;52 (Suppl 1):51-54. 23. Cook IJ. Clinical disorders of the upper esophageal sphincter. In: Goyal and Shaker’s GI Motility Online; Edited by Goyal, RK and Shaker, R Nature Publishing Group; New York, 2006: doi:10.1038/gimo37. 24. Galmiche JP, Clouse RE, Baunt A, Cook IJ, Kahrilas PJ, Paterson WG, Smout AJPM. Functional esophageal disorders. Gastroenterology 2006: 130:1459-65. 25. Cook IJ. Diagnostic evaluation of dysphagia. Nat Clin Pract Gastroenterol Hepatol 2008;5:393-403. 26. Cook IJ. Oropharyngeal dysphagia. In: Talley NJ, Tangalos EG, eds. Gastroenterol Clin N Am; Gastroenterology in the Elderly: Saunders, 2009:38:411-31. 27. Cook IJ, Talley NJ, Benninga MA, Rao SS, Scott SM. Chronic constipation: Overview and challenges. Neurogastroenterol Mot 2009;21(s2):1-8.CONFERENCE PROCEEDINGS1. Cook IJ. Colonic motor disorders. In: Dent J, ed. Pharmacotherapy of gastrointestinal motor disorders. Adelaide, Oct 1990. Sydney: Reed Healthcare Communications, 1991; 51-56.2. Cook IJ. Is the irritable bowel syndrome (IBS) an intestinal motor disorder? Proceedings, bowel motility workshop. Oiso, Japan, Feb 1991. In; Therapeutic Research. Tokyo, Japan, Life Science Publishing Company, 1992;13(1):543-554.3. Cook IJ. Alimentary effects of denervation: contractility after vagotomy. Arnold EP, Meirrilees M (eds), Proceedings, Smooth muscle: basic science applied to clinical medicine. Auckland School of Medicine, March, 1995, 60-63.4. Cook IJ. Is intestinal smooth muscle contractility altered in irritable bowel syndrome? Arnold EP, Meirrilees M (eds), Proceedings, Smooth muscle: basic science applied to clinical medicine.. Auckland School of Medicine, March, 1995, 49-53. 1 8

Cook IJ Updated 07/07/20105. Williams RB, Pal A, Brasseur JG, Cook IJ. Biomechanics of swallowing: Development and application of spatio-temporal maps of multichannel pressure data recorded from the pharyngo-esophageal segment. (Oral presentation, Engineering and Physical Sciences in Medicine 2000 Conference, Newcastle, Australia, November 2000).MISCELLANEOUS PUBLISHED MATERIAL1. Goulston KJ, Cook IJ, Dent OF. How important is rectal bleeding in the diagnosis of bowel cancer and polyps? In: Rogers DE, et al, eds. Abstracted: The Year Book of Medicine. Chicago: Year Book Medical Publishers Inc., 1987;505-507.2. Kellow J, Cook I, Heap T, Steadman C. Irritable bowel syndrome. G.P. & patient information booklets. Australian Gastroenterology Institute 1994.3. Cook IJ. Cricopharyngeal function and dysfunction (Letter). Dysphagia 1994; 9:131.INVITED PAPERS (National and international meetings)1. Cook IJ. Stress and the esophagus. 1st International Workshop on Stress and Digestive Motility. Mont Gabriel, Canada, March 1989.2. Cook IJ. IBS-irritable mind, irritable gut or both? Symposium on Current Management of Irritable Bowel Syndrome. Hamilton, Canada, March 1989.3. Cook IJ. Assessment of oral-pharyngeal dysphagia. Royal Australian College of Surgeons Conference, Melbourne, May 1989.4. Cook IJ. Cricopharyngeal dysphagia - approach to management. Gastroenterological Society of Australia, Perth, May 1989.5. Cook IJ. Oropharyngeal dysphagia - investigation and management. World Congress of Gastroenterology, Sydney, August 1990.6. Cook IJ. Is the irritable bowel syndrome (IBS) a gastrointestinal motility disorder? Keynote Speaker, Bowel Motility Workshop, Oiso, Japan, February 1991.7. Cook IJ. Physiology and pathophysiology of the upper esophageal sphincter and pharynx. Symposium; American Gastroenterological Association Meeting, New Orleans, USA, May 1991.8. Cook IJ. G.I. Motility: a practical perspective. G.E. Society of Australia Motility Workshop, Brisbane, April 1992.9 Cook IJ. Gastrointestinal sensory dysfunction in disease. Symposium on gastrointestinal sensation. Gastroenterological Society of Australia, Brisbane, April 1992.10. Cook IJ. Advanced training in gastroenterology - Whats ideal? Symposium, Gastroenterological Society of Australia, Brisbane, April 1992. 1 9

Cook IJ Updated 07/07/201011. Cook IJ. Gastroesophageal Reflux Disease. Keynote Address. Gastroenterological Society of New Zealand Glaxo Meeting, Waitomo, NZ, April 1993.12. Cook IJ. Physiopathology of Zenker’s Diverticulum; International Symposium on Surgery of the Oesophagus, Universte Catholique de Louvain, Brussels, December 1993.13. Cook IJ. Dysmotility syndromes - oropharyngeal dysphagia. Symposium, Australian Gastroenterology Week, Australian Gastroenterological Society, Sydney, August, 1994.14. Cook IJ. Esophageal afferent dysfunction in pharyngeal syndromes. Symposium: Esophago- pharyngeal interrelationships. Dysphagia Research Society Conference, McLean, Virginia, USA, October 1994.15. Cook IJ. Effects of vagotomy on alimentary smooth muscle contractility. Symposium: Smooth Muscle: Basic Science Applied to Clinical Medicine, Auckland, March, 1995.16. Cook IJ. Smooth muscle contractility in irritable bowel syndrome. Symposium: Smooth Muscle: Basic Science Applied to Clinical Medicine, Auckland, March, 1995.17. Cook IJ. Difficult Dysphagia. Interactive symposium, Clinical Update Conference, Gastroenterological Society of Australia, Leura, April 1995.18. Cook IJ. Gastro-oesophageal reflux - assessing severity. Symposium. Royal Australasian College of Physicians Annual Conference, Canberra, May 1996.19. Cook IJ. Normal and pathophysiological motility of the human colon and ileocolonic junction. Gastrointestinal Motility Workshop, AGW, Gastroenterological Society of Australia, Adelaide, Sept 1996.20. Cook IJ. Principles of oesophageal function testing. Symposium: Practicalities of oesophageal function testing, GENSA Conference, Adelaide, Sept 1996.21. Cook IJ. Gastro-oesophageal reflux disease. National Dysphagia Symposium, Royal Prince Alfred Hospital, Sydney, Sept 1996.22. Cook IJ. Clinical assessment of the upper oesophageal sphincter. National Dysphagia Symposium, Royal Prince Alfred Hospital, Sydney, Sept 1996.23. Cook IJ. Current approaches to the assessment and management of pharyngeal dysphagia. South Carolina Gut Club, Columbia, South Carolina, Oct 1996.24.Cook IJ. State of the Art Lecture: Pharyngeal manometry: research tool or accepted clinical test?Dysphagia Research Society Meeting, Aspen, Colorado, Nov 1996.25.Cook IJ. Symposium: Mechanical aspects of swallowing relating to the pharynx. DysphagiaResearch Society Meeting, Aspen, Colorado, Nov 1996.26.Cook IJ. Working party report: Terminology and analysis of intestinal pressure waves.International Motility Symposium, Lorne, Feb 1998. 2 0

Cook IJ Updated 07/07/201027.Cook IJ. Invited lecturer; University of Southern California, Medical and Surgical Aspects ofEsophageal and Foregut Disorders: Pathophysiology and Treatment. (4 lectures on aspects ofesophageal and pharyngeal dysphagia). Hawaii, Feb 1998.28.Cook IJ. Controversies in the management of gastro-oesophageal reflux disease. Clinical UpdateConference, Gastroenterological Society of Australia, Hamilton Island, March 1998.29. Cook IJ. Pathophysiology of upper esophageal dysfunction. International Society for Diseases of the Esophagus, Montreal, Sept 1998.30. Cook IJ. Management of dysphagia - dilatation. Dysphagia Research Society Conference, New Orleans, Oct 1998.31. Cook IJ. Current concepts in the pathophysiology of disorders of the upper oesophageal sphincter. Scottish Motility Society, Sterling, Scotland, Nov 1998.32. Cook IJ. Pathophysiology of constipation. Janssen Asia Pacific Advisory Board Meeting, Hong Kong, May 1999.33. Cook IJ. Gut Feelings: from organ bath to therapy of IBS. What is the problem: sensory or motor? Australian Gastroenterology Week, Brisbane, Oct 1999.34. Cook IJ. Gut Feelings: from organ bath to therapy of IBS. Current and future pharmacotherapy. Australian Gastroenterology Week, Brisbane, Oct 1999.35. Cook IJ. Small bowel, colon and anorectum: Motor disorders and their diagnosis. International Symposium on Gastrointestinal Motility, Japan Digestive Diseases Week, Hiroshima, Oct 1999.36. Cook IJ. How effective are existing therapies in IBS? Symposium: “IBS, a new era in therapy”. Stuttgart, June 2000.37. Cook IJ. The biomechanics of the upper esophageal sphincter during swallowing. Dysphagia Research Society Conference, Savannah, Georgia, October 2000.38. Cook IJ. New concepts and management approaches for functional constipation. Motility Workshop, Asia Pacific Digestive Week, Sydney, Sept 2001.39. Cook IJ. Difficult dysphagia due to dysmotility. Breakfast session. Asia Pacific Digestive Week, Sydney, Sept 2001.40. Cook IJ. Cough - Is it reflux. Symposium on laryngo-respiratory complications of gastroesophageal reflux disease. Dysphagia Research Society Conference, Albuqurque, USA, Oct 2001.41. Cook IJ. A current classification of esophageal motor dysfunction. Symposium: Clinical syndromes of esophageal motor dysfunction. World Congress of Gastroenterology, Bangkok, Feb 2002. 2 1

Cook IJ Updated 07/07/201042. Cook IJ. Dysphagia and constipation in the patient with CNS disease. Symposium: The motility consultation: how to help the internist. World Congress of Gastroenterology, Bangkok, Feb 2002.43. Cook IJ. Targeting mechanisms underlying constipation. Neurogastroenterology and Motility Workshop, Australian Gastroenterology Week, Adelaide, Oct 2002.44.Cook IJ. Swallowing after stroke. Symposium: Motility in Unusual Places, AustralianGastroenterology Week, Adelaide, Oct 2002.45. Cook IJ. Extra-esophageal manifestations of reflux disease: diagnosis and management. Hong Kong Motility Society. Hong Kong, Nov 2003.46. Cook IJ. Oropharyngeal dysphagia. Symposium: Esophageal Motility Disorders, Second Asian-Pacific Course on Gastrointestinal Motility, Seoul, Korea, Nov 2003.47. Cook IJ. Laryngopharyngeal reflux disease. Symposium: Gastroesophageal Reflux Disease, Second Asian-Pacific Course on Gastrointestinal Motility, Seoul, Korea, Nov 2003.48.Cook IJ. To and fro across the upper oesophageal sphincter. British Society of GastroenterologyConference, Glasgow, March 2004.49. Cook IJ. Biomechanics of the upper esophageal sphincter (UES) – does it influence current management? Annual Meeting, Society of Swallowing and Dysphagia of Society of Swallowing and Dysphagia of Japan, Hamamatsu, Japan, Feb 2005.50. Cook IJ. Symposium; Laryngitis and GERD: “Reflux laryngitis is a hoax.” Digestive Diseases Week, American Gastroenterological Association, Chicago, May 2005.51.Cook IJ. Symposium: Swallowing disorders in the elderly. Idiopathic pharyngeal dysphagia.World Congress of Gastroenterology, Montreal, Sept 2005.52.Cook IJ. Irritable bowel syndrome; pathogenesis and implications for therapy. Varenna GroupWorking Party Presentation. World Congress of Gastroenterology, Montreal, Sept 2005.53.Cook IJ. The pathogenesis of disorders affecting the upper oesophageal sphincter. WorldCongress of the International Society for Diseases of the Oesophagus, Adelaide, February 2006.54.Cook IJ. Extra oesophageal manifestations of gastro-oesophageal reflux. Insights from trials ofmedical therapy. World Congress of the International Society for Diseases of the Oesophagus,Adelaide, February 2006.55.Cook IJ, Shaker R. Oropharyngeal Dysphagia. American Gastroenterology AssociationPostgraduate Course, Digestive Diseases Week, Los Angeles, May 2006.56.Cook IJ. Globus – What causes that sensation? 8th World Congress of O.E.S.O., Avignon, Sept2006.57.Cook IJ. Can activation of peripheral sensory pathways be exploited to treat neuromyogenicdysphagia? 8th World Congress of O.E.S.O., Avignon, Sept 2006. 2 2

Cook IJ Updated 07/07/201058.Cook IJ. An approach to dysphagia. Australian Gastroenterology Week, Adelaide, Oct 2006.59.Cook IJ. Esophageal Manometry and Impedance Testing. Multidisciplinary Workshop onInstrumental Evaluation and Management of Dysphagia; Dysphagia Research Society, Vancouver,March 2007.60.Cook IJ. What does the speech pathologist needs to know about the esophagus? DysphagiaResearch Society, Vancouver, March 2007.61.Cook IJ. The interest of GABA-B agonists in PPI-resistant GERD patients. 9th World Congressof O.E.S.O., Monaco, April 2008.62.Cook IJ. Normal function of the upper oesophageal sphincter and its relationship to high cervicaldysphagia. Symposium: Oesophageal structure and function in health and disease. University ofAdelaide, Sept 2008.63.Cook IJ. Challenges in constipation. Current Perspectives in Chronic Constipation: A scientificand clinical symposium. Queen Mary University of London. London. Feb 2009.64.Cook IJ. Classification, definitions and diagnostic categories of constipation. CurrentPerspectives in Chronic Constipation: A scientific and clinical symposium. Queen Mary Universityof London. London. Feb 2009.65.Cook IJ. Pneumatic dilatation is the optimal therapy for achalasia. Australian GastroenterologyWeek, Sydney, Oct 2009.OTHER INVITED CONTRIBUTIONS TO SCIENTIFIC MEETINGS(National and international) 1. Chairman, Symposium on Reflux Oesophagitis, O.E.S.O. Meeting, Paris, September 1993. 2. Moderator, Symposium, Esophago-pharyngo-laryngeal interrelationships. Dysphagia Research Society Conference, McLean, Virginia, USA, October 1994. 3. Chairman Symposium: “Reflux in the Laparoscopic Era”, Gastroenterological Society of Australia, Perth, Oct, 1995. 4. Chairman, Workshop: Definitions and classification of intestinal pressure waves. International Motility Symposium, Lorne, Feb 1998. 5. Chairman Symposium: Barrett’s Oesophagus, Gastroenterological Society of Australia, Clinical Update Conference, Hamilton Island, March 1998. 6. Chairman Postgraduate Course Symposium: Difficult Constipation, Gastroenterological Society of Australia Annual Conference, Hobart, Oct 2000. 7. Chairman Symposium: Clinical Motility. Neurogastroenterology and Motility Workshop, Australian Gastroenterology Week, Adelaide, Oct 2002. 2 3

Cook IJ Updated 07/07/2010 8. Chairman Symposium: Swallowing disorders in the elderly. World Congress of Gastroenterology, Montreal, Sept 2005 9. Chairman Symposium: Definition of reflux disease. World Congress of the International Society for Diseases of the Oesophagus, Adelaide, February 2006. 10. Moderator: Brain-Foregut Connections; Plenary Session, 8th World Congress of O.E.S.O., Avignon, Sept 2006. 11. Moderator Symposium: The Esophagus. Dysphagia Research Society, Vancouver, March 2007. 12. Chairman Plenary Session: Extra-esophageal manifestations of GERD Clinical evaluation and diagnosis, 9th World Congress of O.E.S.O., Monaco, April 2008. 13. Chairman Topic Forum: Prevention of aspiration in GERD, 9th World Congress of O.E.S.O., Monaco, April 2008.INVITATIONS: VISITING PROFESSORSHIPSMay 2000 Visiting Professor, Northwestern University Medical School, Chicago, USAJun 2001 Visiting Professor, The Canberra Hospital, ACT.OTHER INVITED PRESENTATIONS AT ACADEMIC INSTITUTIONS “Current Approaches to the Assessment of Oral-Pharyngeal Dysphagia”, Gastrointestinal Unit, Westmead Hospital, Sydney, 1991. “Pharyngeal Manometry in Dysphagia”, Gastrointestinal Unit, Royal North Shore Hospital, Sydney, 1992. “Current Concepts in the Irritable Bowel Syndrome”, Medical Grand Rounds, St Vincents Hospital, Sydney, 1992. “Cricopharyngeal Function and Dysfunction”, Gastroenterology Unit, Concord Hospital; May 1993 “Current Research in Dysphagia”; Dysphagia Interest Group, Concord Hospital, Nov 1993. “How Does Aging Influence Swallowing?” Gastrointestinal Unit, Prince of Wales Hospital, November, 1994. “Afferent and efferent mechanisms controlling swallowing”. Neurosciences Centre, Flinders University, Adelaide, August, 1995. “Has pharyngeal manometry come of age?”. South Australian Motility Society, University of 2 4

Cook IJ Updated 07/07/2010Adelaide, August, 1995.“The current place of pharyngeal manometry in clinical practice: Melbourne Gut Club,Melbourne, Oct, 1995.“Approach to difficult dysphagia” Grand Rounds, Princess Alexandra Hospital, Brisbane,June, 1996.“Advances in the understanding human colonic filling, transit and defaecation”.Gastroenterology Department, Royal North Shore Hospital, July 1996.“Reflux oesophagitis”, Surgical training course, Royal Australian College Surgeons, RNSH,Sydney, Feb 1997.“The assessment of dysphagia”. Grand Rounds, Repatriation General Hospital, Concord,May 1998.“Manometry in the evaluation of dysphagia”. Gastroenterology Department, Royal PrinceAlfred Hospital, Sydney, May 1998.“The impact of newer measurement techniques on the understanding of upper esophagealsphincter function and dysfunction.” Seminar, NorthWestern University Medical School,Chicago, May 2000.“New approaches to oral-pharyngeal dysphagia.” Grand Rounds, Nepean Hospital, WesternSydney, June 2000."New dysphagia measurement tools", Symposium, Developmental Disabilities Conference,St George Hospital, Sydney, Nov 2000“Evolving concepts in the pathophysiology of constipation.” Gastroenterology Unit Meeting,Royal Canberra Hospital, June 2001.“Current concepts of the non-gastrointestinal manifestations of reflux disease.” GrandRounds, Royal Canberra Hospital, June 2001.“Dysphagia in the elderly.” Training session, Advanced trainees in GerontologySymposium, St George Hospital, Sept 2001.“Swallowing after stroke.” St George Hospital Annual Symposium, St George Hospital,Nov 2002.“Oropharyngeal dysphagia: diagnostic, management and feeding issues.” FeedingConference – Feeding through life’s stages, St George Hospital, Oct 2006.“The normal function of the upper oesophageal sphincter and its relationship to high cervicaldysphagia and to Zenker’s diverticulum.” Oesophageal Structure and Function in Health andDisease Seminar, University of Adelaide, March 2008.“How to approach the patient with dysphagia.” Grand Rounds. Concord Hospital. May 2 5

Cook IJ Updated 07/07/2010 2008.BOOK REVIEWS1. Read NW. (Ed). Irritable Bowel Syndrome. Blackwell Scientific Publications, Oxford, 1991. Aust NZ J Med 1992;22 (4): 396.2. Kamm M, Lennard-Jones JE. (Eds). Gastrointestinal Transit: Pathophysiology and Pharmacology. Wrightson Biomedical Publishing, Petersfield, Hampshire, 1991. Aust NZ J Med 1992; 22(6): 719.AUDIO-VISUAL WORKS AND EXHIBITIONS1. Cook IJ, Castell DO, Jones B, Castell JA. Clinical symposium: Physiology and pathophysiology of the upper esophageal sphincter. Audio tape recorded at Digestive Diseases Week, New Orleans, 1991. (Timonium, Maryland, Miler-Fenwick, 1991).2. Cook IJ. “Health Issues in the Elderly - management of reflux disease”. Audiotape for GPs, Edition #21, Drivetime Radio Productions, Sydney, August, 1995.3. Cook IJ. “Pathogenesis and Management of Reflux Disease”. Multimedia interactive computer programme for General Practitioners, 1996.PUBLISHED ABSTRACTS1. Boden R, Cook IJ, Stephen M, Gallagher N, Shulkes A. Diarrhoea and hypokalaemia due to a pancreatic tumour secreting neurotensin, VIP and pancreatic polypeptide. Aust NZ J Med 1983;13:316. (Presented Australian Gastroenterological Society, Sydney, Oct 1981).2. Cook IJ, de Carle D, Haneman B, Hunt D, Talley N. The role of routine brush cytology in the diagnosis of gastric lesions. Aust NZ J Med 1983;13:444. (Presented Australian Gastroenterological Society, Perth, May 1983).3. Borody T, Byrnes D, Kamath K, Cook IJ. Atropine suppression test for pancreatic polypeptide secreting tumours. Dig Dis Sci 1983;28:927.4. Cook IJ, Pavli P, Riley JW, Goulston KJ. Is colonic investigation necessary in iron deficient patients with demonstrable upper gastrointestinal pathology? Aust NZ J Med. 1985;15 (Suppl):175. (Presented Australian Gastroenterological Society, Adelaide, October 1984).5. Cook IJ, Pavli P, Riley J, Goulston KJ. Gastrointestinal investigation of iron deficiency anaemia. Gastroenterology 1985;88:1355. (Presented American Gastroenterological Association, New York, May 1985).6. Cook IJ, Reddy SN, Daniel EE, Collins SM. Measurement of colonic motility: Validation and comparison of existing techniques. Gastroenterology 1986;90:1380. (Presented Smooth 2 6

Cook IJ Updated 07/07/2010 Muscle Function Symposium [satellite symposium of XXX Int Congr Int Union of Phys Sciences] Banff, Canada, July 1986).7. Cook IJ, van Eeden A, Collins SM. Irritable bowel syndrome patients have higher cutaneous pain thresholds than normals. Gastroenterology 1986;90:1380. (Presented American Gastroenterological Association, San Francisco, May 1986).8. Cook IJ, Collins SM. Does acute emotional stress influence frequency or duration of gastroesophageal reflux in human subjects? Gastroenterology 1986;90:1380.9. Cook IJ, Dent J, Shannon S, Collins SM. Measurement of upper esophageal sphincter pressure: the effect of stress. Gastroenterology 1986;91:1049. (Oral presentation, American Motility Society, Houston, Texas, October 1986.)10. Cook IJ, Dent J, Shannon S, Silleti C. The effect of stress on upper oesophageal sphincter pressure. Aust NZ J Med 1987;17 (Suppl):129. (Presented Australian Gastroenterological Society, Surfers Paradise, Sept 1986).11. Cook IJ, Dent J, Shannon S, Collins SM. Evidence for central nervous system control of the lower esophageal sphincter from its response to vestibular stimulation. Gastroenterology 1987;92:1353. (Oral presentation American Gastroenterological Association, Chicago, May 1987).12. Cook IJ, Dent J, Collins SM. The influence of stress on symptoms and upper esophageal sphincter pressure in patients with globus sensation. Gastroenterology 1987;92:1354. (Presented American Gastroenterological Association, Chicago, May 1987).13. Anvari M, Dent J, Waterfall WE, Cook IJ, Anvari P. Motor responses of the upper esophageal sphincter to physical straining. Gastroenterology 1987;92:1297.14. Lamping DL, Cook IJ, Beckett CM, Campbell D, Irvine EJ, Collins SM. The relationship between the perception of clinical and experimentally induced pain in patients with irritable bowel syndrome. (Presented American Association of Behavioural Therapists, Boston, November 1987).15 Cook IJ, Irvine EJ, Campbell D, Shannon S, Reddy SN, Collins SM. Effect of dietary fiber on symptoms and colonic motility in patients with IBS: A crossover study. Gastroenterology 1988;94:A77. (Oral presentation American Gastroenterological Association, New Orleans, May 1988).16. Cook IJ, Lamping D, Campbell D, Saxe G, Irvine EJ, Collins SM. Determinants of symptom reports in patients with IBS: Role of psychological disposition and responses to pain. Gastroenterology 1988;94:A77.17. Cook IJ, Massey BT, Dantas RO, Dodds WJ, Hogan WJ. Alterations in oral-pharyngeal deglutition caused by increases in swallowed bolus volume. Gastroenterology 1988;94:A77. (Presented American Gastroenterological Association, New Orleans, May 1988).18. Cook IJ, Dodds WJ, Dantas R, Massey B, Kern M, Hogan WJ. Mechanisms and pressure- flow kinetics of upper esophageal sphincter opening during swallowing. Gastroenterology 2 7

Cook IJ Updated 07/07/2010 1988;94:A76. (Presented American Gastroenterological Association, New Orleans, May 1988).19. Cook IJ, Irvine EJ, Campbell D, Shannon S, Reddy SN, Collins SM. Effect of dietary fibre on symptoms and colonic motility in patients with IBS. Aust NZ J Med 1988;18:412. (Presented Australian Gastroenterological Society, Sydney, May 1988).20. Cook IJ, Lamping D, Campbell D, Saxe G, Irvine EJ, Collins SM. Determinants of symptom reports in patients with IBS: The role of psychological disposition and responses to pain. Aust NZ J Med 1988;18:406. (Presented Australian Gastroenterological Society, Sydney, May 1988).21. Cook IJ, Massey BT, Dantas R, Dodds WJ, Hogan WJ. Alterations in oro-pharyngeal deglutition caused by increases in swallowed bolus volume. Aust NZ J Med 1988;18:400. (Presented Australian Gastroenterological Society, Sydney, May 1988).22. Cook IJ, Dantas R, Dodds WJ, Massey B, Kern M, Hogan WJ. Mechanisms and pressure- flow kinetics of upper oesophageal sphincter opening during swallowing. Aust NZ J Med 1988;18:396. (Presented Australian Gastroenterological Society, Sydney, May 1988).23. Shaker R, Cook IJ, Dodds, WJ, Hogan WJ, Arndorfer RC. Pressure-flow dynamics of the oral phase of swallowing. Gastroenterology 1988;94:A421. (Oral presentation American Gastroenterological Association, New Orleans, May 1988).24. Dantas RO, Massey BT, Kern MK, Cook IJ, Dodds WJ. Effect of bolus volume and viscosity on the pharyngeal phase of swallowing. Gastroenterology 1988;95:861. (American Motility Society, Asilomar, California, October 1988).25. Cook IJ. The influence of psychological stress on esophageal motility. Dig Dis Sci 1989;33:4-82. (Oral presentation: International workshop on stress and digestive motility, Mont Gabriel Canada, March 1989).26. Cook IJ, Shaker R, Dodds WJ, Hogan WJ, Arndorfer RC. Role of mechanical and chemical stimulation of the esophagus in globus sensation. Gastroenterology 1989;96:A99. (Presented American Gastroenterological Association, Washington DC, May 1989).27. Cook IJ, Gabb M, Panagopoulos V, Jamieson GG, Hains JD, Dodds WJ, Dent J, Shearman DJ. Zenkers diverticulum: a defect in upper esophageal sphincter compliance. Gastroenterology 1989;96:A98. (Oral presentation American Gastroenterological Association, Washington DC, May 1989).28. Cook IJ, Blumbergs P, Cash K, Graham S, Jamieson GG, Hains JD, Shearman DJ. Zenkers diverticulum: evidence for a restrictive cricopharyngeal myopathy. Gastroenterology 1989;96:A98. (Oral presentation American Gastroenterological Association, Washington DC, May 1989).29. Cook IJ, Dantas RO, Dodds WJ, Lang IM. Manometric and videoradiographic analysis of cricopharyngeal bars. Gastroenterology 1989;96:A98. (Presented American Gastroenterological Association, Washington DC, May 1989). 2 8

Cook IJ Updated 07/07/201030. Lang IM, Dantas RO, Cook IJ, Dodds WJ. Manometric, videoradiographic, and electromyographic evaluation of upper esophageal sphincter function in the dog. Gastroenterology 1989;96:A286. (Presented American Gastroenterological Association, Washington DC, May 1989).31. Dantas RO, Dodds WJ, Kern MK, Massey BT, Cook IJ. Bolus volume and consistency: Effect on oral and pharyngeal phases of swallowing. Gastroenterology 1989;96:A109. (Presented American Gastroenterological Society, Washington DC, May 1989).32. Cook IJ, Gabb M, Panagopoulos V, Jamieson GG, Hains JD, Dodds WJ, Dent J, Shearman DJ. Zenkers diverticulum: A defect in upper oesophageal sphincter compliance? Aust NZ J Med 1989;19:584. (Presented Australian Gastroenterological Society, Perth, May 1989).33. Cook IJ, Blumbergs P, Cash K, Graham S, Jamieson GG, Hains JD, Shearman DJ. Is dysphagia in Zenkers diverticulum caused by a restrictive myopathy of the cricopharyngeus muscle? Aust NZ J Med 1989;19:585. (Presented Australian Gastroenterological Society, Perth, May 1989).34. Cook IJ, Shaker R, Dodds WJ, Hogan WJ. Globus sensation: role of mechanical and chemical stimulation of the oesophagus. Aust NZ J Med 1989;19:591. (Presented Australian Gastroenterological Society, Perth,May 1989).35. Shaw DW, Cook IJ, Dent J, Simula ME, Panagopoulos V, Gabb M, Shearman DJ. Age influences oropharyngeal and upper esophageal sphincter function during swallowing. Gastroenterology 1990;98:A390. (Oral presentation American Gastroenterological Association, San Antonio, Texas, May 1990).36. Shaw DW, Collins PJ, Simula ME, Cook IJ, Shearman DJ. Oropharyngeal scintigraphy: a reliable technique for the quantitative evaluation of oral-pharyngeal swallowing. Gastroenterology 1990;98:A390. (Presented American Gastroenterological Association, San Antonio, Texas, May 1990).37. Shaw DW, Cook IJ, Simula ME, Jamieson GG, Holloway RH, Gabb M, Dent J. Restoration of normal upper esophageal sphincter compliance following cricopharyngeal myotomy in patients with Zenkers diverticulum. Gastroenterology 1990;95:A122. (Oral presentation American Gastroenterological Association, San Antonio Texas, May 1990).38. Cook IJ, Furukawa Y, Panagopoulos V, Collins PJ, Simula M, Dent J. Correlation between intraluminal pressures and movement of contents in the healthy human colon: A combined manometric and isotope transit study. Gastroenterology 1990;98:A338. (Oral presentation American Gastroenterological Association, San Antonio Texas, May 1990).39. Furukawa Y, Cook IJ, Panagopoulos V, Simula M, McEvoy D, Sweeney J, Shearman D. Regional and diurnal variation in human colonic pressure activity characterised by prolonged pan-colonic manometry. Gastroenterology 1990;98:A352. (Presented American Gastroenterological Association, San Antonio Texas, May 1990).40. Furukawa Y, Cook IJ, Panagopoulos V, Simula ME, McEvoy D, Sweeney J, Shearman D. Regional and diurnal variation on human colonic pressure activity characterised by prolonged pan-colonic manometry. Aust NZ J Med 1990;20:376. (Presented Australian 2 9

Cook IJ Updated 07/07/2010 Gastroenterological Society, Melbourne, May 1990).41. Cook IJ, Furukawa Y, Panagopoulos V, Collins PJ, Simula ME, Dent J. Correlation between intraluminal pressures and movement of contents in the healthy human colon: A combined manometric and isotope transit study. Aust NZ J Med 1990;20:370. (Presented Australian Gastroenterological Society, Melbourne, May 1990).42. Shaw D, Collins PJ, Simula ME, Cook IJ, Shearman DJ. Oropharyngeal scintigraphy: A reliable technique for the quantitative evaluation of oral-pharyngeal swallowing. Aust NZ J Med 1990;20:375. (Presented Australian Gastroenterological Society, Melbourne, May 1990)43. Shaw SW, Cook IJ, Simula M, Jamieson GG, Holloway R, Gabb M, Dent J. Restoration of normal upper oesophageal sphincter compliance following cricopharyngeal myotomy in patients with Zenkers diverticulum. Aust NZ J Med 1990;20:370. (Presented Australian Gastroenterological Society, Melbourne, May 1990).44. Shaw DW, Cook IJ, Simula ME, Panagopoulos V, Gabb M, Shearman DJ. Age influences oropharyngeal and upper oesophageal sphincter function during swallowing. Aust NZ J Med 1990;20:375. (Presented Australian Gastroenterological Society, Melbourne, May 1990).45. Furukawa Y, Cook IJ, Panagopoulos V, McEvoy D, Sharp D, Simula M. Relationships between sleep patterns and human colonic motor patterns. Gastroenterology 1991;100:A443. (Oral presentation American Gastroenterological Association, New Orleans, May 1991.)46. Furukawa Y, Cook IJ, Panagopoulos V, Dent J, Simula M, Sweeny J. The influence of bowel preparation and spontaneous colonic filling on colonic pressures. Gastroenterology 1991; 100:A443.47. Anvari M, Cook I, Dent J, Anvari P, Waterfall WE. Protection of airways from esophagopharyngeal reflux during physical straining. Gastroenterology 1991;100:A415. (Presented American Gastroenterological Association, New Orleans, May 1991).48. Furukawa Y, Cook IJ, Panagopoulos V, Dent J, Simula M, Sweeney J. The influence of bowel preparation and spontaneous colonic filling on colonic pressures. Aust NZ J Med 1991; 21:560. (Presented Australian Gastroenterological Society, Adelaide, May 1991.)49. Furukawa Y, Cook IJ, Panagopoulos V, McEvoy D, Sharp D, Simula M. Relationship between sleep patterns and human colonic motor patterns. Aust NZ J Med 1991;21:573. (Presented Australian Gastroenterological Society, Adelaide, May 1991).50. Johnsson F, Shaw D, Gabb M, Cook IJ. Does body posture or gravity influence oropharyngeal and upper esophageal sphincter function during swallowing? Gastroenterology 1992;102:A464. (Presented American Gastroenterological Association, San Francisco, May 1992).51. Gillespie D, de Carle DJ, Cook IJ, Wallace KL. The mechanism of chest pain in achalasia. Gastroenterology 1992;102:A451. 3 0

Cook IJ Updated 07/07/201052. Weltman MD, Shaw DW, Wallace KL, McKay E, Perabo D, Cook IJ. Normal ageing impairs the efficiency of pharyngeal but not oral emptying during swallowing - a scintigraphic study. Gastroenterology 1992;102:A533. (Presented American Gastroenterological Association, San Francisco, May 1992).53. Weltman MD, Wallace KL, Cook IJ, McKay E, Smart R, de Carle DJ, Butler P. How useful are scintigraphic measures in predicting regional dysfunction in patients with oral- pharyngeal dysphagia? Gastroenterology 1992;102:A533. (Presented Aust & N.Z. Society of Nuclear Medicine, Adelaide, May 1992).54. Weltman MD, Shaw DW, Wallace KL, McKay E, Perabo D. Cook IJ. Normal ageing impairs the efficiency of pharyngeal but not oral emptying during swallowing - A scintigraphic study. J Gastroenterol Hepatol 1992;7:A24. (Presented Gastroenterological Society of Australia, Brisbane, April 1992.)55. Johnsson F, Shaw D, Gabb M, Cook IJ. Does body posture or gravity influence oropharyngeal and upper oesophageal sphincter function during swallowing? J Gastroenterol Hepatol 1992;7:A24. (Presented Gastroenterological Society of Australia, Brisbane, April 1992.)56. Weltman MD, Wallace KL, Cook IJ, McKay E, Smart R, de Carle DJ, Butler P. How useful are scintigraphic measures in predicting regional dysfunction in patients with oral- pharyngeal dysphagia? J Gastroenterol Hepatol 1992;7:A25. (Presented Gastroenterological Society of Australia, Brisbane, April 1992.)57. Ali GN, Laundl TM, Shaw DW, de Carle DJ, Cook IJ. Are Mucosal receptors important in the control of pharyngeal and UES function during swallowing? Gastroenterology 1993;140 (2): A469. (Oral presentation, American Gastroenterological Association, Boston, May 1993.)58. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. Is the pharyngeal swallow response a triggered reflex? Gastroenterology 1993;140 (2): A469.59. Cook IJ, Ali GN, Laundl TM, Wallace KL, de Carle DJ. The influence of mucosal afferent receptors in the control of the oral-pharyngeal swallow. Proceedings OESO conference, 1994. (Oral presentation, OESO meeting, Paris, September 1993).60. Ali GN, Wallace KL, Schwartz R, Zagami A, de Carle DJ, Cook IJ. Oral-pharyngeal dysfunction in patients with Parkinson’s Disease and dysphagia. J Gastroenterol Hepatol 1993;8(5):A26. (Oral presentation Australian Gastroenterology Week, Melbourne, September 1993).61. Ali GN, Laundl TM, Shaw DW, de Carle DJ, Cook IJ. Do mucosal receptors influence the control of pharyngeal UES function during swallowing? J Gastroenterol Hepatol 1993;8(5):A26. (Oral presentation Australian Gastroenterology Week, Melbourne, September 1993).62. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. Is the pharyngeal swallow response a triggered reflex? J Gastroenterol Hepatol 1993;8(5):A26. (Presented Australian Gastroenterology Week, Melbourne, September 1993). 3 1

Cook IJ Updated 07/07/201063. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. Is the pharyngeal swallow response a triggered reflex? Dysphagia 1994;9:pp. (Oral presentation Dysphagia Research Society Second Annual Scientific Meeting October 1993, Wisconsin USA).64. Ali GN, Wallace KL, Laundl TM, Hunt DR, de Carle DJ, Cook IJ. Predictors of symptomatic outcome following cricopharyngeal (CP) disruption (myotomy or dilatation) in pharyngeal dysphagia. Gastroenterology 1994;106(4):A458. (Oral presentation, American Gastroenterological Association, New Orleans, May 1994.)65. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Glenn D, Cook IJ. Influence of oral mechanoreceptors on upper esophageal sphincter (UES) and pharyngeal function during deglutition. Gastroenterology 1994;106(4):A458.66. Ali GN, Wallace KL, Laundl TM, Schwartz A, Zagami A, de Carle DJ, Cook IJ. Oral- pharyngeal dysfunction in patients with Parkinson’s disease and dysphagia. Gastroenterology 1994;106(4):A459. (Oral presentation, American Gastroenterological Association, New Orleans, May 1994.)67. Ali GN, de Carle DJ, Wallace KL, Laundl TM, Cook IJ. The horizontal water swallow test: a simple and accurate bedside diagnostic test for achalasia. Gastroenterology 1994;106(4):A39. (Presented American Gastroenterological Association, New Orleans, May 1994.)68. Lim SK, Jorgensen JO, de Carle DJ, Hunt DR, Wallace KL, Ali GN, Cook IJ. Pneumatic dilatation for achalasia: a review of long term symptomatic outcome. Gastroenterology 1994;106(4):A125. (Presented American Gastroenterological Association, New Orleans, May 1994.)69. Ali GN, Hunt DR, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. A new technique for direct measurement of upper esophageal sphincter (UES) muscle compliance: preliminary results. Gastroenterology 1994;106(4):A458.70. Ali GN, Laundl TM, Wallace KL, de Carle DJ, Glenn D, Cook IJ. Oral mechanoreceptors influence upper oesophageal sphincter (UOS) and pharyngeal function during deglutition. J Gastroenterol Hepatol 1994;9(5):A93. (Presented Gastroenterological Society of Australia, Sydney, September 1994).71. Ali GN, de Carle DJ, Wallace KL, Laundl TM, Cook IJ. The horizontal water swallow test: a simple and accurate bedside diagnostic test for achalasia. J Gastroenterol Hepatol 1994;9(5):A109. (Presented Gastroenterological Society of Australia, Sydney, September 1994).72. Ali GN, Hunt DR, Laundl TM, Wallace KL, de Carle DJ, Cook IJ. A new technique for direct measurement of upper oesophageal sphincter (UOS) muscle compliance: preliminary results. J Gastroenterol Hepatol 1994;9(5):A110. (Presented Gastroenterological Society of Australia, Sydney, September 1994).73. Ali GN, Wallace KL, Laundl TM, Hunt DR, de Carle DJ, Cook IJ. Predictors of symptomatic outcome following cricopharyngeal (CP) disruption in pharyngeal dysphagia. J 3 2

Cook IJ Updated 07/07/2010 Gastroenterol Hepatol 1994;9(5):A110. (Presented Gastroenterological Society of Australia, Sydney, September 1994).74. Ali GN, Wallace KL, Hunt DR, deCarle DJ, Cook IJ. Evidence for a central cause for coexistent failed relaxation of upper and lower esophageal sphincters - a case report. Gastroenterology 1995;108(4):A561.75. Williams RB, Ali GN, Wallace KL, deCarle DJ, Cook IJ. Detection of acid regurgitation with a pharyngeal pH electrode: validation of measurement criteria. Gastroenterology 1995;108(4):A258. (Presented American Gastroenterological Association Meeting, San Diego, May, 1995).76. Ali GN, Wallace KL, deCarle DJ, Cook IJ. Effect of bolus temperature on regulation of upper esophageal sphincter (UES) and pharyngeal function during deglutition. Gastroenterology 1995;108(4):A561.77. Wallace KL, Ali GN, de Carle DJ, Cook IJ.Development and validation of a new self-report inventory to assess severity of oral-pharyngeal dysphagia. Gastroenterology 1995;108(4):A252. (Presented American Gastroenterological Association Meeting, San Diego, May, 1995).78. Williams RB, Ali GN, Wallace KL, deCarle DJ, Cook IJ. Detection of acid regurgitation with a pharyngeal pH electrode: validation of measurement criteria. J Gastroenterol Hepatol 1995;10 (Suppl 2):A31. (Presented Gastroenterological Society of Australia, Perth, Oct 1995).79. Wallace KL, Ali GN, deCarle DJ, Cook IJ. Development and validation of a new self-report inventory to assess severity of oral-pharyngeal dysphagia. J Gastroenterol Hepatol 1995;10 (Suppl 2):A32. (Presented Gastroenterological Society of Australia, Perth, Oct 1995).80. Dinning PG, Cook IJ, Kennedy ML, deCarle DJ, Lubowski DZ. Motor events in the human ileocolonic junction. J Gastroenterol Hepatol 1995;10 (Suppl 2):A51. (Oral presentation, Gastroenterological Society of Australia, Perth, Oct 1995).81. Hope RL, Wallace KL, Gillespie DA, Hunt DR, deCarle DJ, Cook IJ. Relationship between oesophageal diverticula and dysmotility. J Gastroenterol Hepatol 1995;10 (Suppl 2):A53. (Oral presentation, Gastroenterological Society of Australia, Perth, Oct 1995).82. Cook IJ, Dinning PG, Kennedy ML, deCarle DJ, Lubowski DZ.Development of a new technique for the measurement of motor events in the human ileocolonic junction. J Neurogastroenterol Motil 1995;7(4):252. (Oral presentation, International Motility Society Conference, Rome, Nov, 1995).83.Cook IJ, Wallace KL, Ali GN, Zagami AS, Enis JM. Mechanisms of pharyngeal dysphagia inlateral medullary syndrome (LMS). Gastroenterology 1996;110(4):A650. (Oral presentation,American Gastroenterology Association conference, San Francisco, May 1996).84. Dinning PG, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Manometric findings in the unprepared proximal colon in patients with severe obstructed defecation. Gastroenterology 1996;110(4):A657. (Presented, American Gastroenterology Association conference, San 3 3

Cook IJ Updated 07/07/2010 Francisco, May 1996).85. Hope RL, Wallace KL, Gillespie DA, Hunt DR, de Carle DJ, Cook IJ. Relationship between esophageal diverticulum and dysmotility.Gastroenterology 1996;110(4):A681. (Presented, American Gastroenterology Association conference, San Francisco, May 1996).86. Williams RB, Wallace KL, Ali GN, Hunt DR, de Carle DJ, Cook IJ. Does cricopharyngeal myotomy promote oesophago-pharyngeal regurgitation? J Gastroenterol Hepatol 1996;11(Suppl):A89. (Presented at Gastroenterological Society of Australia, Adelaide, Sept 1996).87. Williams RB, Wallace KL, Ali GN, Lovell NH, de Carle DJ, Cook IJ. Intraluminal electromyographic (EMG) recordings from the upper oesophageal sphincter during deglutition; results in normal human subjects. J Gastroenterol Hepatol 1996;11(Suppl):A104. (Presented at Gastroenterological Society of Australia, Adelaide, Sept 1996).88. Dinning PG, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Nasocolonic manometric recordings of the unprepared proximal colon from patients with severe obstructed defaecation. J Gastroenterol Hepatol 1996;11(Suppl):A111. (Presented at Gastroenterological Society of Australia, Adelaide, Sept 1996).89. Kajimoto T, Dinning PG, de Carle DJ, Cook IJ. Neurogenic pathways mediating ileo- sphincteric and colo-sphincteric reflexes in the porcine ileocolonic junction. J Gastroenterol Hepatol 1996;11(Suppl):A111. (Presented at Gastroenterological Society of Australia, Adelaide, Sept 1996).90. Wallace KL, Williams RB, de Carle DJ, Cook IJ. Oral mechanoreceptors in the tongue may regulate temporal relationships in the swallow sequence. J Gastroenterol Hepatol 1996;11(Suppl):A112. (Presented at Gastroenterological Society of Australia, Adelaide, Sept 1996).91. Wallace KL, Cook IJ, Ali GN, Zagami AS, Enis JM. Swallow pathophysiology in lateral medullary syndrome. J Gastroenterol Hepatol 1996;11(Suppl):A122. (Oral presentation, Gastroenterological Society of Australia, Adelaide, Sept 1996).92. Kajimoto T, Dinning PD, Gibb D, de Carle DJ, Cook IJ. Neurogenic pathways mediating ileo and colo-sphincteric reflexes at the porcine ileocolonic junction. Gastroenterology 1997;112(4): A758. (Presented American Gastroenterological Association conference, Washington, May 1997).93. Williams RB, Wallace KL, Ali GN, Lovell HN, de Carle DJ, Cook IJ. Feasibility of intraluminal EMG recordings from the human upper esophageal sphincter (UES): a concurrent manometric, videoradiographic and EMG study of deglutition. Gastroenterology 1997; 112(4):A851. (Presented American Gastroenterological Association conference, Washington, May 1997).94. Bampton PA, Dinning PG, Kennedy ML, de Carle DJ, Lubowski DZ, Cook IJ. The Influence of bowel preparation on the frequency and characteristics of propagating pressure waves in the human colon. Gastroenterology 1997; 112(4):A694. (Presented American 3 4

Cook IJ Updated 07/07/2010 Gastroenterological Association conference, Washington, May 1997).95. Williams RB, Wallace KL, Ali GN, Cook IJ. Upper esophageal sphincter (UES) compliance and opening characteristics in neurogenic dysphagia with failed sphincter relaxation. Gastroenterology 1997;112(4):A852. (Oral presentation, American Gastroenterological Association conference, Washington, May 1997).96. Wallace KL, Leahey D, Hunt DR, de Carle DJ, Cook IJ. Randomised controlled trial of cricopharyngeal myotomy in patients with pharyngeal dysphagia. Gastroenterology 1997; 112(4):A848. (Presented American Gastroenterological Association conference, Washington, May 1997).97. Wallace KL, Williams RB, de Carle DJ, Cook IJ. Bolus Confinement in the oral cavity abolishes volume dependency of deglutitive UES relaxation. Gastroenterology 1997;112(4):A848. (Presented American Gastroenterological Association conference, Washington, May 1997).98. Williams RB, Wallace KL, Ali GN, Hunt DR, de Carle DJ, Cook IJ. Cricopharyngeal myotomy does not increase the risk of esophagopharyngeal acid regurgitation. Gastroenterology 1997;112(4):A331 (Presented American Gastroenterological Association conference, Washington, May 1997).99. Williams RB, Wallace KL, Ali GN, Cook IJ. Biomechanical consequences of failed deglutitive upper oesophageal sphincter (UOS) relaxation in neurogenic dysphagia.J Gastroenterol Hepatol 1997;12(Suppl):A25. (Presented Gastroenterological Society of Australia, Brisbane, Oct 1997).100. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Colonic manometric characteristics of spontaneous defaecation. J Gastroenterol Hepatol 1997;12(Suppl):A36. (Oral presentation, Gastroenterological Society of Australia, Brisbane, Oct 1997).101. Wallace KL, Leahey D, Hunt DR, de Carle DJ, Cook IJ. Cricopharyngeal myotomy in patients with pharyngeal dysphagia - a randomised controlled trial.J Gastroenterol Hepatol 1997;12(Suppl):A38. (Presented Gastroenterological Society of Australia, Brisbane, Oct 1997).102. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Distal ileal motor activity: a trigger of colonic motor events. J Gastroenterol Hepatol 1997;12(Suppl):A44. (Presented Gastroenterological Society of Australia, Brisbane, Oct 1997).103. Dinning PG, Bampton PA, Kennedy ML, Omari T, Lubowski DZ, deCarle DJ, Cook IJ. Prolonged closely spaced multipoint perfusion manometry of the entire unprepared human colon. J Gastroenterol Hepatol 1997;12(Suppl):A105. (Oral presentation at Gastroenterological Society of Australia, Brisbane, Oct 1997).104. Zekry A, Wallace KL, de Carle DJ, Hersch M, Cook IJ. Myasthenia gravis presenting as oral-pharyngeal dysphagia: diagnostic utility of pharyngeal manometry. J Gastroenterol Hepatol 1997;12(Suppl):A90. (Presented Gastroenterological Society of Australia, Brisbane, 3 5

Cook IJ Updated 07/07/2010 Oct 1997).105. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, de Carle DJ, Cook IJ. Manometric characterisation of spontaneous defaecation. Neurogastroenterol Motil 1998;10 (1):A59. (Oral presentation, International Motility Symposium, Lorne, Feb 1998).106. Bampton PA, Dinning PG, Kennedy ML, Omari T, de Carle DJ, Cook IJ. Prolonged multipoint perfusion manometry of the entire unprepared human colon. Neurogastroenterol Motil 1998;10 (1):A60. (Oral presentation, International Motility Symposium, Lorne, Feb 1998).107. Williams RB, Zekry A, Cook IJ. The mechanics of rumination and the role of lower esophageal sphincter (LES) relaxations. Gastroenterology 1998; 114(4):A2911.108. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. High amplitude propagating pressure wave sequences: toward a logical definition. Gastroenterology 1998; 114(4):A2964. (Presented American Gastroenterological Association conference, New Orleans, May 1998)109. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. The manometric correlates of spontaneous defecation in obstructed defecation: evidence for a pancolonic disorder. Gastroenterology 1998; 114(4):A2965. (Presented American Gastroenterological Association conference, New Orleans, May 1998)110. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. Propagating distal ileal motor events: a stimulus for nocturnal colonic propagating sequences. Gastroenterology 1998; 114(4):A3072. (Presented American Gastroenterological Association conference, New Orleans, May 1998)111. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. The colonic meal response: insights from unprepared pancolonic multipoint perfusion manometry. Gastroenterology 1998; 114(4):A3073. (Presented American Gastroenterological Association conference, New Orleans, May 1998)112. Williams RB, Zekry A, Cook IJ. Biomechanics of rumination and the role of LOS relaxation. J Gastroenterol Hepatol 1998;13 (Suppl) A171 (Presented at Australian Gastroenterology Week, Canberra, October 1998)113. Bampton PA, Dinning PG, Kennedy M, Lubowski DZ, deCarle DJ, Cook IJ. Rectal chemoreceptors and mechanoreceptors differentially stimulate pressure patterns in the unprepared proximal colon. Digestion 1998; 59(3)(Supp):670 (Presented, World Congress of Gastroenterology, Vienna, Sept 1998)114. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, deCarle DJ, Cook IJ. The development of a 16 channel extruded silicon nasocolonic manometric assembly. Digestion 1998; 59(3) (Supp):670 (Presented, World Congress of Gastroenterology, Vienna, Sept 1998)115. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. Rectal chemoreceptors and mechanoreceptors differentially stimulate pressure patterns in the unprepared proximal 3 6

Cook IJ Updated 07/07/2010 colon. J Gastroenterol Hepatol 1998; 13 (Suppl):A188. (Oral presentation, Australian Gastroenterology Week, Canberra, October 1998)116. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. High amplitude propagating sequences: a valid subdivision of colonic propagating pressure sequences. J Gastroenterol Hepatol 1998; 13 (Suppl):A153. (Presented, Australian Gastroenterology Week, Canberra, October 1998)117. Bampton PA, Dinning PG, Kennedy ML, Lubowski DZ, Cook IJ. The manometric correlates of spontaneous defaecation in obstructed defaecation suggests a pancolonic disorder. J Gastroenterol Hepatol 1998; 13 (Suppl):A201 (Oral presentation, Australian Gastroenterology Week, Canberra, October 1998)118. Dinning PG,Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. The colonic meal response as recorded by multipoint pancolonic manometry of the unprepared colon. J Gastroenterol Hepatol 1998; 13 (Suppl):A197. (Oral presentation, Australian Gastroenterology Week, Canberra, October 1998)119. Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. Technical advancement in the development of silastic catheters for per nasal colonic manometry. J Gastroenterol Hepatol 1998;13 (Suppl):A196. (Presented, Australian Gastroenterology Week, Canberra, October 1998)120.Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. Periodic rectal motoractivity: is it pancolonic? J Gastroenterol Hepatol 1998;13 (Suppl):A183. (Presented, AustralianGastroenterology Week, Canberra, October 1998).121.Dinning PG, Bampton PA, Cook IJ. Are rectal motor complexes (RTC) unique to the rectum?Neurogastroenterology and Motility 1999;11(4):A259. (Presented 17th International Symposium onGastrointestinal Motility, Bruges, Belgium, September 1999).122.Williams RB, Andre J, Grehan MJ, Hersch M, Cook IJ. Pharyngeal and upper esophagealsphincter (UES) mechanics in myositis-related pharyngeal dysphagia. Neurogastroenterology andMotility 1999;11(4):A301. (Presented 17th International Symposium on Gastrointestinal Motility,Bruges, Belgium, September 1999).123.Bampton PA, Dinning PG, Kennedy ML, Cook IJ. Colonic manometric recording sites - ismore better? J Gastroenterol Hepatol 1999;14(Suppl):A132. (Oral presentation, AustralianGastroenterology Society Conference, Brisbane, Oct 1999).124.Grehan MJ, Williams RB, Hersch M, Andre J, Cook IJ. Diagnosis of and treatment outcome ininflammatory myopathy presenting as oropharyngeal dysphagia. J Gastroenterol Hepatol 1999; 14(Suppl): A136. (Oral presentation, Australian Gastroenterology Society Conference, Brisbane, Oct1999).125.Grehan MJ, Park G, Russell D, Cook IJ, Jones DB, Yeomans N, Howden CW. Misconceptionsof Australian residents and interns about colorectal cancer screening - need for further education. JGastroenterol Hepatol 1999; 14 (Suppl): A177. (Oral presentation, Australian GastroenterologySociety Conference, Brisbane, Oct 1999). 3 7

Cook IJ Updated 07/07/2010126.Williams RB, Andre J, Grehan MJ, Hersch M, Cook IJ. Pharyngeal and upper esophagealsphincter (UES) mechanics in myositis-related pharyngeal dysphagia. J Gastroenterol Hepatol 1999;14 (Suppl): A184. (Presented, Australian Gastroenterology Society Conference, Brisbane, Oct1999).127.Pekin ME, Cook IJ. Schatzki ring: reasons for delay in diagnosis and long term response todilatation. J Gastroenterol Hepatol 1999;14 (Suppl):A196. (Oral presentation, AustralianGastroenterology Society Conference, Brisbane, Oct 1999).128.Williams RB, Cook IJ. Temporal patterns of acidification in oesophago-pharyngeal acidregurgitation: what can they tell us about the underlying mechanisms? J Gastroenterol Hepatol1999;14(Suppl):A200. (Oral presentation, Australian Gastroenterology Society Conference,Brisbane, Oct 1999).129.Hunt DR, Wills VL, Weiss B, Jorgensen JO, de Carle DJ, Cook IJ. The management ofoesophageal perforation after pneumatic dilatation for achalasia. J Gastroenterol Hepatol1999;14(Suppl): A203. (Oral presentation, Australian Gastroenterology Society Conference,Brisbane, Oct 1999)130.Williams RB, Pal A, Brasseur JG, Cook IJ. Isocontour interpolation from high resolutionperfusion manometry applied to the pharyngo-esophageal segment during deglutition.Gastroenterology 2000;118(Suppl):A2127 (Presented, American Gastroenterological Associationmeeting, San Diego, May, 2000).131.Pal A, Williams RB, Cook IJ and Brasseur JG. Intrabolus pressure gradient as a diagnosticmeasure of restricted UES opening Gastroenterology 2000;118(Suppl):A2117 (Presented, AmericanGastroenterological Association meeting, San Diego, May, 2000)132.Grehan MJ, Williams R, Hersch M, Andre J and Cook IJ. Diagnosis of and treatment outcomein inflammatory myopathy presenting as oropharyngeal dysphagia. Gastroenterology2000;118(Suppl):A4768 (Oral presentation, American Gastroenterological Association meeting, SanDiego, May, 2000).133.Pekin ME, Cook IJ. Schatzki ring: reasons for delay in diagnosis and long term response todilatation. Gastroenterology 2000;118(Suppl):A1432. (Presented, American GastroenterologicalAssociation meeting, San Diego, May, 2000).134.Williams RBH, Pal A, Brasseur JG, Cook IJ. Application of high resolution perfusionmanometry and spatio-temporal pressure maps to the pharyngo-esophageal segment in normalswallowing. J Gastroenterol Hepatol 2000:15(Suppl):J10 (Presented, Australian GastroenterologyWeek, Hobart, October 2000)135.Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, Cook IJ. Distribution andcharacteristics of colonic propagating pressure wave sequences in “outlet delay” constipation. JGastroenterol Hepatol 2000:15(Suppl):J27 (Presented, Australian Gastroenterology Week, Hobart,October 2000)136.Williams RBH, Pal A, Brasseur JG, Cook IJ. New insights into diagnosis and biomechanics ofrestrictive upper oesophageal sphincter opening disorders provided by spatio-temporal pressuremaps. J Gastroenterol Hepatol 2000:15(Suppl):J69 (Presented, Australian Gastroenterology Week, 3 8

Cook IJ Updated 07/07/2010Hobart, October 2000)137.Hui JM, Hunt DR, deCarle DJ, Cook IJ. Oesophageal dilatation for post-fundoplicationdysphagia: safety, efficacy and predictors or outcome. J Gastroenterol Hepatol 2000:15(Suppl):J73(Oral presentation, Australian Gastroenterology Week, Hobart, October 2000)138.Dinning PG, Andre J, Bampton PA, Kennedy ML, Lubowski DZ, Cook IJ. Patients withobstructed defaecation lack the normal pre-defaecatory augmentation of colonic propagatingpressure wave sequences. J Gastroenterol Hepatol 2000:15(Suppl):J75 (Presented, AustralianGastroenterology Week, Hobart, October 2000)139.Brasseur JG, Pal A, Williams RB, Cook IJ. Intrabolus pressure gradient localizes pathologicalconstrictions in the upper esophageal sphincter (UES) during flow. Dysphagia 2001:16(2); 149(Oral presentation Dysphagia Research Society Conference, Savannah, USA, October 2000).140.Pal A, Brasseur J, Williams RB, Cook IJ. Application of computer simulation to the evaluationof pathophysiology of the pharyngo-esophageal (PE) segment. Gastroenterology 2001:120(5) Suppl1; A221. (Presented American Gastroenterological Association conference, Atlanta, May 2001).141.Dinning PG, Bampton PA, Andre J, Kennedy ML, Lubowski DZ, King DW, Cook IJ.Constipation due to obstructed defaecation is likely to be a colonic rather than an ano-rectaldisorder. Gastroenterology 2001:120(5)(Suppl1);A751. (Presented American GastroenterologicalAssociation conference, Atlanta, May 2001).142.Williams RB, Cook IJ. Automated feature extraction and classification of pharyngeal pHsignals for the detection of esophagopharyngeal acid regurgitation. Neurogastroenterology andMotility 2001;13(4):442. (Presentation 18th International Symposium on Neurogastroenterology andMotility, Madison, WI USA, Sep 16-20 2001).143.Hui JM , Hunt DR, de Carle DJ, Cook IJ. Esophageal dilatation for post-fundoplicationdysphagia: safety, efficacy and predictors of outcome. Dysphagia, 2002:17(2);177. (Presentation at10th Annual Dysphagia Research Society Meeting, Albuqerque, New Mexico, USA, October 2001).144.Williams RB, Cook IJ. Novel method for automated detection and morphological analysis ofpharyngo-esophageal pH data from ambulatory, 24-hour pH studies. Journal of Gastroenterologyand Hepatology 2001:16; (Suppl) A101.(Asia-Pacific Digestive Week Conference, Sydney,September 2001).145.Williams RB, Cook IJ. Towards optimal detection of oesophagopharyngeal acid regurgitationusing statistical pattern classifiers: preliminary results. Journal of Gastroenterology and Hepatology2001:16;(Suppl);A100. (Presented, Asia-Pacific Digestive Week Conference, Sydney, Sept 2001).146.Ng A, Sourjina T, Williams RB, de Carle DJ, Cook IJ. Does adequacy of oesophageal contrastemptying during routine gastrograffin swallow predict outcome following pneumatic dilatation forachalasia? Journal of Gastroenterology and Hepatology 2001:16;A100. (Oral presentation, Asia-Pacific Digestive Week Conference, Sydney, Sept 2001).147.Dinning PG, McKay E, Smart R, Cook IJ. Motor correlates of caecal filling: a combinedmanometric and scintigraphy study of human ileocolonic transit. Journal of Gastroenterology and 3 9

Cook IJ Updated 07/07/2010Hepatology 2001:16;A99. (Oral presentation, Asia-Pacific Digestive Week Conference, Sydney,Sept 2001).148.Williams R, Cook IJ, Shaker R, Brasseur J. Application of computer simulation to theevaluation of pathophysiology of the pharyngo-esophageal (PE) segment. Dysphagia2002:17(2);177. (Oral presentation, DRS conference, Albuqurque, New Mexico, Oct 2001).149.Williams RB, Cook I. Preliminary observations on the mechanisms of esophago-pharyngealregurgitation in human subjects. Gastroenterology 2002;122(4) A190 (Presented AmericanGastroenterological Association conference, Sans Francisco May 2002).150.Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King D, Cook IJ. Heightened rectalsensory thresholds and blunted recto-colonic motor reflexes implicated in constipation due toobstructed defaecation. Gastroenterology 2002; 122(4) A316 (Presented AmericanGastroenterological Association conference, Sans Francisco May 2002).151.Dinning PG, Cook IJ. The motor correlates of ileocecal transit; a combined manometric andscintigraphic study of the human ileocolonic junction. Gastroenterology 2002; 122(4) A319(Presented American Gastroenterological Association conference, Sans Francisco May 2002).152.Williams RB, Lazarus C, Rademaker A, Pavlovski B, Cook IJ. Scintigraphic validation ofradiographic estimation of oral and pharyngeal clearance on modified barium swallow inoropharyngeal dysphagia. Gastroenterology 2002; 122(4) A359 (Presented AmericanGastroenterological Association conference, Sans Francisco May 2002).153.Williams RB, Cook IJ. Detection of esophagopharyngeal acid regurgitation using dual pHmonitoring: application of statistical classification methodology. Gastroenterology 2002;12(4):A577 (Presented American Gastroenterological Association conference, Sans Francisco May2002).154.Williams RB, Maclean JC, Brake HM, Cole IE, Cook IJ. Predictors of outcome in an open,therapeutic trial of omeprazole in patients with laryngitis. Gastroenterology 2002;122(4): A580(Presented American Gastroenterological Association conference, San Francisco May 2002).155.Williams RB, Maclean JC, Brake HM, Cole IE, Cook IJ. Predictors of outcome in an opentherapeutic trial of omeprazole in patients with laryngitis. J Gastroenterol Hepatol 2002:17;A194(Oral presentation: Australian Gastroenterology Week, Adelaide October 2002 )156.Williams RB, Lazarus C, Rademaker A, Pauloski B, Cook IJ, Logemann JA. Scintigraphicvalidation of radiographic estimation of oral and pharyngeal clearance on modified barium swallowin oropharyngeal dysphagia. J Gastroenterol Hepatol 2002: 17;A192 (Presented AustralianGastroenterology Week, Adelaide October 2002 )157.Williams RB, Szczesniak MM, Cook IJ. Preliminary observations of mechanisms of esophago-pharyngeal acid regurgitation in human subjects. J Gastroenterol Hepatol 2002:17;A193 (PresentedAustralian Gastroenterology Week, Adelaide October 2002 )158.Szczesniak MM, Williams RB, Cook IJ. Activation of distension-induced oesophago-UOSrelaxation response is upregulated in patients with posterior laryngitis. J Gastroenterol Hepatol2002:17;A207 (Oral presentation: Australian Gastroenterology Week, Adelaide October 2002). 4 0

Cook IJ Updated 07/07/2010159.Dinning PG, Cook IJ. Removal of tonic nitrergic inhibition stimulates human ileal and colonicpropagating sequences. Neurogastroenterol Mot 2003;15:591-681:A295. (Oral presentation atInternational Motility Society, Barcelona, Spain).160.Dinning PG, Szczesniak M. Cook IJ. The relationships among caecal filling and ileal andcolonic propagating sequences. Neurogastroenterol Mot 2003;15:591-681:A299. (Oral presentationat International Motility Society, Barcelona, Spain).161.Dinning PG, Bampton PA, Kennedy ML, Lubowski DZ, King D, Cook IJ. The frequency ofretrograde colonic propagating sequences may depend upon colonic loading. NeurogastroenterolMot 2003;15:591-681:A330. (Poster presentation at International Motility Society, Barcelona,Spain).162.Dinning PG, Burnette A, Talley NJ, Lubowski DZ, King DW, Cook IJ. Development andvalidation of a questionnaire for assessing symptom subgroups in severe constipation.Neurogastroenterol Mot 2003;15:591-681:A332.163.Stanton MP, Hutson JM, Simpson D, Oliver MR, Southwell BR, Dinning PG,Cook IJ, Catto-Smith AG. Colonic manometry in children with slow transit constipation shows reduced frequency,amplitude and length of propagating sequences. Gastroenterol 2003; 124(suppl 1):A513.164.Omari T, Rommel N, Szczesniak M, Funentealba S, Dinning PG, Cook IJ. Complexities ofdetection of pharyngeal bolus flow using multichannel intraluminal impedance. Gastroenterology2004; 126:A112. (Oral presentation, American Gastroenterological Association, New Orleans, USA,May 2004)165.Rommel N. Omari T, Szczesniak M, Funentealba S, Dinning PG, Cook IJ. Evaluation ofintraluminal impedance for the assessment of pharyngeal bolus flow during swallowing.Gastroenerol Hepatol. 2004. 19 (supp):A281. (Oral presentation, Australian Gastroenterology Week,Brisbane, Australia, Oct 2004)166.Dinning PG, Fuentealbas S.E, Kennedy ML, Lubowski DZ, Cook IJ. Sacral nerve stimulationinitiates propagating pressure waves throughout the colon in patients with slow transit constipation.Neurogastroenterol Motility 2005; 17 (Supp 2): A76. (Oral presentation, International MotilitySociety, Toulouse, France, July 2005)167.Dinning PG, McKay E, Cook IJ. Validation of a semi-automated scintigraphic technique fordetecting episodic, real time colonic flow. Neurogastroenterol Motility 2005; 17 (Supp 2): A93.(Poster presentation, International Motility Society, Toulouse, France, July 2005)168.King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Lee M, Southwell B, Dinning P, Cook I,Catto-Smith A. Substance P deficiency and colonic motility in paediatric slow transit constipation.Neurogastroenterol Motility 2005; 17 (Supp 2):A78. (Oral presentation (S. King), InternationalMotility Society, Toulouse, France, July 2005)169.King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Lee M, Southwell B, Dinning P, Cook I,Catto-Smith A. The impact of interferential therapy on paediatric slow transit constipation:manometric evidence of success. Neurogastroenterol Motility 2005; 17 (Supp 2): A261. (Posterpresentation, International Motility Society, Toulouse, France, July 2005) 4 1

Cook IJ Updated 07/07/2010170.King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Southwell B, Dinning P, Cook I, Catto-Smith A. 24-hour colonic manometry in paediatric slow transit constipation using a per-appendicostomy approach. Neurogastroenterol Motility 2005; 17 (Supp 2):A260. (Posterpresentation, International Motility Society, Toulouse, France, July 2005)171.Szczesniak MM, Fuentealba SE, Anthea B. Cook IJ. Modulation of distension-induced upperesophageal sphincter (UES) reflexes. Neurogastroenterol Motility 2005; 17 (Supp 2):A36. (Oralpresentation, International Motility Society, Toulouse, France, July 2005)172.Dinning PG, Fuentealba S.E, Kennedy ML, Lubowski DZ, Cook IJ. Stimulation of the sacralnerve S3 induces antegrade propagating sequences throughout the colon in patients with slow transitconstipation. Gastroenterol Hepatol 2005:20 (Suppl): A96 (Oral presentation at the AustralianGastroenterology Week, Brisbane, Australia, Oct 2005)173.Dinning PG, McKay E, Cook IJ. Validating a scintigraphic technique for detecting episodic,real-time colonic flow. Gastroenterol Hepatol 2005; 20 (Suppl):A97 (Poster presentation, AustralianGastroenterology Week, Brisbane, Australia, Oct 2005)174.King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Southwell B, Dinning P, Cook I, Catto-Smith A. 24-hour colonic manometry demonstrates dysmotility in paediatric slow transitconstipation and evidence of improvement following transcutaneous electrical stimulation.Gastroenterol Hepatol 2005; 20 (Suppl):A92. (Oral presentation (S. King), AustralianGastroenterology Week, Brisbane, Australia, Oct 2005)175. Omari T, Arkwright J, Doe S, Szczesniak M, Rommel N, Dinning P, Cook I. Manometry in the 21st Centry: A Novel Fibre Optic Based Technology for Multi-Channel Intraluminal Manometry. Gastroenterology 2006; 130(4)(Suppl2):A577. (Poster of distinction, American Gastroenterological Association, Los Angeles, USA, May 2006)176. Omari T, Szczesniak M, Rommel N, Dinning P, Fuentealba S, Cook I. Intraluminal Impedance Detects Failure of Pharyngeal Bolus Clearance During Swallowing: A Validation Study in Adult Dysphagia Patients. Gastroenterology 2006; 130(4)(Suppl2):A730. (Poster presentation, American Gastroenterological Association, Los Angeles, USA, May 2006)177. Dinning PG, Fuentealba S.E, Kennedy ML, Lubowski DZ, Cook IJ. Sacral nerve stimulation initiates propulsive pressure waves throughout the colon in patients with slow transit constipation. Aust NZ J Surg 2006; 76(Suppl. 1):A14 (Oral presentation (P.Dinning), Royal Australasian College of Surgeons Annual Scientific Congress, Sydney 2006).178. King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Lee M, Southwell B, Dinning P, Cook I, Catto-Smith A. Substance P deficiency and colonic motility in paediatric slow transit constipation. Aust NZ J Surg 2006; 76(Suppl.1):A52 (Poster presentation, Royal Australasian College of Surgeons Annual Scientific Congress, Sydney 2006).179.King S, Hutson J, Stanton M, Simpson D, Sutcliffe J, Lee M, Southwell B, Dinning P, Cook I,Catto-Smith A. The impact of interferential therapy on paediatric slow transit constipation:manometric evidence of success. Aust NZ J Surg 2006; 76(Suppl. 1):A47 (Oral presentation (PDinning), Royal Australasian College of Surgeons Annual Scientific Congress, Sydney 2006). 4 2

Cook IJ Updated 07/07/2010180. McKey P, Dinning PG, Fuentealba S.E, Kennedy ML, Lubowski DZ, Cook IJ Sacral Nerve Stimulation Initiates Propagating Pressure Waves Throughout the Colon in Patients with Slow Transit Constipation. Colorectal Disease. 2006;8(2):22-23. (Oral presentation (P.Dinning), Association of Coloproctology, London, July 2006)181. Dinning PG, Fuentealba S.E, Kennedy ML, Lubowski DZ, Cook IJ. Electrical stimulation of the S3 sacral root increased the frequency of both colonic high amplitude propagating pressure waves and defaecation in patients with slow transit constipation. Colorectal Dis 2006: 8(4): 1-2. (Oral presentation at the European Society of Coloproctology, Lisbon, Portugal, Sept 2006)182Dinning PG, Omari T, Cook IJ. Using combined impedance and manometry in the human ano-rectum to determine the site of origin of the defecating urge. Neurogastroenterol Motil 2006; 18: 690(A79) (Poster presentation at the Joint international society meeting in Neurogastroenterology andGI Motility, Boston, USA, Sept 2006)183. Dinning PG, Omari T, Cook IJ. Determining the site of origin of the defaecatory urge using combined impedance and manometry in the human ano-rectum. Gastroenterol Hep 2006: 21(4): A337 (Oral presentation at the Australian Gastroenterology Week, Adelaide, Australia, Oct 2006)184. Szczesniak M, Rommel N, Dinning P, Fuentealba S, Cook I, Omari T. Validation of intraluminal impedance, a novel non-invasive technique for detection of failure of pharyngeal bolus clearance during swallowing in adults with dysphagia. Gastroenterol Hep 2006: 21(4): A343 (Oral presentation at the Australian Gastroenterology Week, Adelaide, Australia, Oct 2006)185.Szczesniak M, Rommel N, Dinning P, Fuentealba S, Cook I, Omari T. Optimal criteria fordetecting bolus passage across the pharyngeal region with intraluminal impedance recording.Gastroenterol Hep 2006: 21(4): A340 (Poster presentation at the Australian Gastroenterology Week,Adelaide, Australia, Oct 2006)186.Arkwright JW, Doe S, Smith M, Blenman N, Rommel N, Szczesniak MM, Dinning PG, CookIJ, Omari T. The accuracy of fibre optic based manometric sensors for recording of esophagealpressures. Gastroenterology 2007: 132(4 suppl 2): A-25. (Poster presentation at the DigestiveDisease Week, Washington, DC, America, May 2007)187.Dinning PG, Omari T, Cook IJ. Determining the site of origin of the Defaecatory urge usingcombined impedance and manometry in the human ano-rectum. Gastroenterology 2007: 132(4 suppl2): A-21. (Poster presentation at the Digestive Disease Week, Washington, DC, America, May2007)188.Dinning PG, Szczesniak MM, Cook IJ. Twenty-four hour space-time pressure mapping ofcolonic propagating pressure waves: Providing pathophysiological insight into constipation.Neurogastroenterol Mot 2007; 19: 71. (Poster of distinction, at International Motility Society, Jeju,Korea, September 2007)189.Dinning PG, Szczesniak MM, Cook IJ. Aberrant spatio-temporal linkage among sequentialcolonic propagating sequences exists in severe constipation. Neurogastroenterol Mot 2007; 19: 71.(Poster presentation, at International Motility Society, Jeju, Korea, September 2007) 4 3

Cook IJ Updated 07/07/2010190.Dinning PG, Szczesniak MM, Cook IJ. Defining colonic complexes in both health and patientswith severe constipation. Neurogastroenterol Mot 2007; 19: 72. (Poster presentation, at InternationalMotility Society, Jeju, Korea, September 2007)191.Szczesniak M, Rommel N, Dinning P, Fuentealba S, Cook I, Omari T. Optimal criteria fordetecting bolus passage across the pharyngeal region with intraluminal impedance recording.Neurogastroenterol Mot 2007; 19: 54. (Poster presentation, at International Motility Society, Jeju,Korea, September 2007)192.Dinning PG, Szczesniak MM, Cook IJ. Severe constipation demonstrates aberrant spatio-temporal linkage among sequential colonic propagating sequences. Gastroenterol Hep 2007;22(suppl 3): A399. (Oral presentation at the Australian Gastroenterology Week, Perth, Oct 2007)193.Dinning PG, Szczesniak MM, Cook IJ. Frequency of colonic complexes in health and severeconstipation: Defining a new hallmark of colonic dysmotility. Gastroenterol Hep 2007; 22(Suppl3):A397. (Oral presentation at, Australian Gastroenterology Week, Perth, Oct 2007)194.Dinning PG, Szczesniak MM, Cook IJ. Pan-colonic isocontour maps of propagating pressurewave activity: providing pathophysiological insights into constipation. Gastroenterol Hep 2007;22(Suppl 3):A398. (Poster presentation at the Australian Gastroenterology Week, Perth, Oct 2007)195.Szczesniak MM, Fuentealba SE, Cook IJ. Acid sensitisation of Oesophageal mucosal afferents:Implications for symptom perception in patients with Gastro-Oesophageal Reflux Diseases (GORD)and functional heartburn. Gastroenterol Hep 2007; 22(suppl 3):A393. (Oral presentation, AustralianGastroenterology Week, Perth, Oct 2007)196.Elliott TR, Wu P, Fuentealba SE, Szczesniak MM, De Carle DJ, Cook IJ. Long term outcomefollowing pneumatic dilatation for idiopathic achalasia. Gastroenterol Hep 2007; 22(suppl 3):A419.(Oral presentation, Australian Gastroenterology Week, Perth, Oct 2007)197.Dinning PG, Jones M, Fuentealba SE, Talley NJ, Cook IJ. In patients with severe constipation,can we predict delayed colonic transit on the basis of symptoms? Gastroenterology 2008: 134(4suppl 1): A-216. (Presentation at the Digestive Disease Week, San Diego, CA America, May 2008).198.Chen CL, Szczesniak MM, Omari T, Cook IJ. Evidence for esophageal mechanicalhypersensitivity with aberrant viscerosomatic referral in patients with globus. Gastroenterology2008: 134(4 suppl 1): A-560. (Presentation at the Digestive Disease Week, San Diego, CA America,May 2008).199.Chen CL, Szczesniak MM, Omari T, Cook IJ. Identification of impaired bolus transit andclearance by secondary peristalsis in patients with non-obstructive dysphagia. Gastroenterology2008: 134(4 suppl 1): A-716. (Presentation at the Digestive Disease Week, San Diego, CA America,May 2008).200.Elliott TR, Wu PI, Fuentealba SE, Szczesniak MM, de Carle DJ, Cook IJ. Long term outcomefollowing pneumatic dilatation for idiopathic achalasia. Gastroenterology 2008: 134(4)(suppl1):A-727. (Presentation at the Digestive Disease Week, San Diego, CA America, May 2008). 4 4

Cook IJ Updated 07/07/2010201.Dinning PG, Arkwright JW, Szczesniak MM, Fuentealba S, Blenman NG, Underhill ID,Naunder SA, Cook IJ. 72-sensor high-resolution colonic manometry: have we been incorrectlylabelling chronic motor patterns. Gastroenterol Hep 2009; 24(suppl 2):A322. (Presentation atAustralia and New Zealand Medical and Surgical Gastrointestinal Week, Sydney, October 2009).202.Dinning PG, Zarate N, Hunt L, Fuenteabla S, Mohammed SD, Szczesniak MM, Preston SR,Lubowski DZ, Fairclough PD, Lunniss PJ, Scott SM, Cook IJ. Pancolonic manometry demonstratespotential biomarkers of disease in patients with slow transit constipation. Gastroenterol Hep 2009;24(suppl 2):A324. (Presentation at Australia and New Zealand Medical and SurgicalGastrointestinal Week, Sydney, October 2009).203.Dinning PG, Hunt L, Fuentealba SE, Szczesniak MM, Lubowski DZ, Cook IJ. Sacral nervestimulation at sub-sensory levels does not induce colonic propagating pressure waves in patientswith slow transit constipation. Gastroenterol Hep 2009; 24(suppl 2):A325. (Presentation at Australiaand New Zealand Medical and Surgical Gastrointestinal Week, Sydney, October 2009).204.Szczesniak MM, Maclean J, Cotton S, Cook IJ, Perry A. Videomanometric evaluation ofdysphagia following total laryngectomy. Gastroenterol Hep 2009; 24(suppl 2):A343. (Presentationat Australia and New Zealand Medical and Surgical Gastrointestinal Week, Sydney, October 2009).205.Dinning PG, Zarate N, Hunt L, Fuentealba SE, Szczesniak MM, Lutton N, Lubowski DZ,Mohammed SD, Preston S, Scott SM, Cook IJ. Twenty-four hour pan-colonic manometry inpatients with severe slow transit constipation demonstrates diminished propagating pressure waveactivity in the transverse colon. Gastroenterology 2009:136(5); A-222. (Poster presentation,Digestive Diseases Week, Chicago, USA, May 2009).206.Dinning PG, Zarate N, Szczesniak MM, Mohammed SD, Preston S, Scott SM. Cook IJ. Howdoes bowel preparation influence colonic motility and pre-defecatory motor patterns?Gastroenterology 2009:136(5); A-223. (Poster presentation, Digestive Diseases Week, Chicago,USA, May 2009).207.Dinning PG, Arkwright JW, Szczesniak MM, Fuentealba SE, Blenman N, Underhill I, MaunderS, Cook IJ. High-resolution coloic manometry: have we been incorrectly labelling colonic motorpatterns? Gastroenterology 2009:136(5);A-224. (Poster presentation, Digestive Diseases Week,Chicago, USA, May 2009).208.Dinning PG, Jones M, Hunt L, Fuentealba S, Lubowski DZ, Kalantar J, Talley NJ, Cook IJ.Factor analysis identifies subgroups of constipation. Neurogastroenterol Mot 2009; 21(s1): PosterPresentation, A-209, 64. (Poster presentation, at Neurogastroenterology and Motility JointInternational meeting, Chicago, USA, Aug 27-30, 2009).209.Dinning PG, Zarate N, Hunt L Fuentealba S, Szczesniak MM, Lubowski DZ, Mohammed SD,Preston S, Scott SM, Cook IJ. Do Characteristics of low-amplitude, propagating sequences differbetween patients with severe constipation and healthy controls? Neurogastroenterol Mot 2009;21(s1): Poster Presentation, A-102, 35. (Poster presentation, at Neurogastroenterology and MotilityJoint International meeting, Chicago, USA, Aug 27-30, 2009)210.Dinning PG, Zarate N, Szczesniak MM, Mohammed SD, Preston S, Scott SM, Cook IJ.Influence of bowel preparation on the spatiotemporal organization of propagated colonic contractilesequences in healthy control subjects. Neurogastroenterol Mot 2009; 21(s1): Poster Presentation, 4 5

Cook IJ Updated 07/07/2010A-101, 34. (Poster presentation, at Neurogastroenterology and Motility Joint International meeting,Chicago, USA, Aug 2009).211.Dinning PD, Hunt L, Fuentealba S, Lubowski DZ, Cook IJ. Sub-sensory sacral nervestimulation does not induce colonic propagating pressure waves in patients with slow transitconstipation. Neurogastroenterol Mot 2009; Oral Presentation, A-18, 10. (Oral presentation, atNeurogastroenterology and Motility Joint International meeting, Chicago, Aug 2009).212.Arkwright JW, Dinning PG, Underhill ID, Blenman NG, Maunder SA, Szczesniak MM, CookIJ. Closely spaced fibre Bragg grating sensors for detailed measurement of peristalsis in the humangut. OFS-20 2009: (Oral presentation Edinburgh, UK, Oct 2009).213.Dinning PG. Arkwright JW, Szczesniak MM, Fuentealba S, Blenman N, Underhill I, MaunderS, Cook IJ. High resolution colonic manometry provides new insights into the complexities ofperistalsis in the colon – clinical trial results from a 72 element optical fibre manometry catheter.Poster presentation World congress of Gastroenterology. London Nov 2009.214.Dinning PG, Jones M, Hunt L, Lubowski DZ, Kalantar J, Cook IJ. The potential impact oflaxative use on stool form and frequency in patients with slow transit constipation. Gastroenterology2010;138(5 Supp1):S-464. (Oral presentation, Digestive Disease Week, New Orleans, USA, May2010)215. 4 6

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